HUE030028T2 - Antifungális gyógyszerkészítmény - Google Patents

Antifungális gyógyszerkészítmény Download PDF

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Publication number
HUE030028T2
HUE030028T2 HUE08829675A HUE08829675A HUE030028T2 HU E030028 T2 HUE030028 T2 HU E030028T2 HU E08829675 A HUE08829675 A HU E08829675A HU E08829675 A HUE08829675 A HU E08829675A HU E030028 T2 HUE030028 T2 HU E030028T2
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HU
Hungary
Prior art keywords
external use
agent
cellulose
weight
alcohol
Prior art date
Application number
HUE08829675A
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English (en)
Inventor
Takaaki Masuda
Naoto Nishida
Naoko Kobayashi
Hideaki Sasagawa
Original Assignee
Pola Pharma Inc
Nihon Nohyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Pharma Inc, Nihon Nohyaku Co Ltd filed Critical Pola Pharma Inc
Publication of HUE030028T2 publication Critical patent/HUE030028T2/hu

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (6)

    Szabadalmi igsaypoaíök
  1. (1) képlet X-G
    1, Antifungális szer külsöleges alkalmazásra, amely magában foglal: 1) (1} képieíü lulikonazolt; 2) 50 - 95 tömeg % mennyiségben egy alkoholt; 3) 0,1 - 35 tömeg % mennyiségben vizet és/vagy egy anionos felületaktív anyagot; 4} 0,01 ~ 5 tömeg % cellulóz-alapú sűrítő anyagot, ahol a cellulóz-alapú sűrítő anyagot a hidroxí-propil-mettl-cellulóz és a hkiroxi-propíi-eeilulóz közül választjuk; és 5) 1 tömeg % vagy kevesebb gyttlékony oldószert, amely tartalmaz N~?neüí-2-pirtölMöwt és/vagy motü-etil-ketont és nem tartalmaz alkoholt, a külsöleges alkalmazásra szolgáló arürfungális szer teljés tömegére vonatkoztatva,
  2. 2, Az 1, igénypont szerinti anltfúngáíís szer külsöleges alkalmazásra, áltól az: antifungális szer egy-fázlsí? oldat formájú,
  3. 3, Egy készítmény, amely magában foglal: 1) 11) képlett? iuiikonazo.lt; 2) 50 - 95 tömeg % mennyiségben egy alkoholt; 3) 0*1 - 35 tömeg % mennyiségben vizet és/vagy egy aniönos felületaktív anyagot; 4) 0,01 ~ 5 tömeg % cellulóz-alapú sűrítő anyagot, ahol a cellulóz-alapú sűrítő anyagot a hidroxi-propil-metü-celluíoz és a hklroxi-propíbeelltilőz közül választjuk; és 5) 1 tömeg % vagy kevesebb gyúlékony oldószert, amely tartalmaz N-métil-2-pirroiidont es/vagy meiil-eíd-ketont és nem tartalmaz alkoholt, a készítmény teljes tömegére vonaíköz-taiva, alkalmazása egy külsőleges alkalmazásra szolgáló anttihngáiis szer előállítására..
    (i) képlet X-Cl
  4. 4, A 3. iglnyponv szerinti alkalmazás, ahol a készítmény egyfázisú oldat formájú,
  5. 5, A 3. és 4 igénypontok bármelyike szerinti alkalmazás, ahol az antífüngális szer az alábbiak közül választott betegségek kezelésére szolgál: óívar, Candidá-fertőzés, chromophyiosis, és szeborrheás dermaütisz.
  6. 6, Az 5. igénypont szerinti alkalmazás, ahol a betegség szeborrheás dermaütisz.
HUE08829675A 2007-09-05 2008-09-05 Antifungális gyógyszerkészítmény HUE030028T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007229617 2007-09-05

Publications (1)

Publication Number Publication Date
HUE030028T2 true HUE030028T2 (hu) 2017-04-28

Family

ID=40428956

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE08829675A HUE030028T2 (hu) 2007-09-05 2008-09-05 Antifungális gyógyszerkészítmény

Country Status (9)

Country Link
US (2) US9480678B2 (hu)
EP (1) EP2191828B1 (hu)
JP (1) JP5453093B2 (hu)
KR (1) KR20100068271A (hu)
CN (1) CN101808639B (hu)
ES (1) ES2591030T3 (hu)
HU (1) HUE030028T2 (hu)
PL (1) PL2191828T3 (hu)
WO (1) WO2009031644A1 (hu)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ571819A (en) * 2006-03-08 2011-04-29 Nihon Nohyaku Co Ltd External pharmaceutical composition comprising luliconazole and either N-methyl-2-pyrrolidone, propylene carbonate or crotamiton
US8058303B2 (en) * 2006-03-08 2011-11-15 Nihon Nohyaku Co, Ltd Pharmaceutical composition for external use
RU2419429C2 (ru) * 2006-03-08 2011-05-27 Нихон Нохияку Ко.,Лтд. Фармацевтическая композиция для наружного применения
JP5345937B2 (ja) 2007-09-05 2013-11-20 株式会社ポーラファルマ 抗真菌組成物
CN101808637B (zh) 2007-09-05 2013-07-24 宝丽制药股份有限公司 医药组合物
PL2191828T3 (pl) 2007-09-05 2017-02-28 Pola Pharma Inc. Przeciwgrzybicza kompozycja farmaceutyczna
ES2468540T3 (es) * 2009-02-13 2014-06-16 Topica Pharmaceuticals, Inc Formulación antif�ngica
CN102387785B (zh) 2009-04-09 2017-08-25 宝丽制药股份有限公司 抗真菌药物组合物
JP5688406B2 (ja) 2009-04-09 2015-03-25 株式会社ポーラファルマ 抗真菌医薬組成物
CN102481286B (zh) 2009-08-25 2014-02-26 宝丽制药股份有限公司 抗真菌药物组合物
JP5832451B2 (ja) 2010-06-11 2015-12-16 株式会社ポーラファルマ 抗真菌医薬組成物
CN104619703A (zh) 2012-09-14 2015-05-13 宝丽制药股份有限公司 具有结晶习性的晶体以及通过对所述晶体进行加工获得的药物组合物
JP5460797B1 (ja) 2012-09-14 2014-04-02 株式会社ポーラファルマ アミド誘導体及び安定性指標としてのその使用
CN104619704B (zh) 2012-09-14 2017-12-05 宝丽制药股份有限公司 表面自由能用于分化评价晶体的用途，基于表面自由能作为指标评价的晶体，以及通过包含所述晶体制备的药物组合物
US9012484B2 (en) 2012-09-14 2015-04-21 Pola Pharma Inc. Crystal and pharmaceutical preparation containing the same crystal
CN104619320A (zh) 2012-09-14 2015-05-13 宝丽制药股份有限公司 含有卢立康唑的药物组合物
JP5589110B1 (ja) 2013-03-08 2014-09-10 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP5680161B1 (ja) 2013-09-06 2015-03-04 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP5587488B1 (ja) 2013-12-12 2014-09-10 株式会社ポーラファルマ ルリコナゾールを含有する製剤の評価方法及び指標物質
MX2019002047A (es) * 2016-08-29 2019-10-04 F Schanbacher Carl Metodos y composiciones para tratar infecciones fungicas cutaneas.
US11554108B2 (en) 2016-08-29 2023-01-17 Xeropedix, Inc. Methods and compositions for treating cutaneous fungal infections
US10898470B1 (en) 2019-08-13 2021-01-26 Sato Pharmaceutical Co., Ltd. Pharmaceutical composition containing antifungal agent as active ingredient
JP7361004B2 (ja) * 2020-09-08 2023-10-13 信越化学工業株式会社 アルコール組成物の製造方法

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267169A (en) 1978-07-22 1981-05-12 Toko Yakuhin Kogyo Kabushiki Kaisha Novel preparation of clotrimazole
JPS5815909A (ja) 1981-07-22 1983-01-29 Toko Yakuhin Kogyo Kk 抗真菌外用剤
US4636520A (en) 1984-07-16 1987-01-13 Fujisawa Pharmaceutical Co., Ltd. Antifungal composition employing pyrrolnitrin in combination with an imidazole compound
JPH0236572B2 (ja) 1984-11-13 1990-08-17 Hokuriku Pharmaceutical Suteroidoo177monoesuteruganjukuriimuzai
JPS6293227A (ja) 1985-10-19 1987-04-28 Nippon Nohyaku Co Ltd 抗真菌剤
US4764381A (en) 1985-12-06 1988-08-16 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol
JPH0774144B2 (ja) 1986-03-12 1995-08-09 久光製薬株式会社 尿素を含有する皮膚用組成物
US5686489A (en) 1986-12-23 1997-11-11 Tristrata Technology, Inc. Alpha hydroxyacid esters for skin aging
JPH0818983B2 (ja) * 1987-12-08 1996-02-28 塩野義製薬株式会社 水虫治療剤
JPH01242525A (ja) * 1988-03-25 1989-09-27 Nippon Nohyaku Co Ltd 抗真菌外用剤
JPH01246219A (ja) 1988-03-25 1989-10-02 Nippon Nohyaku Co Ltd 抗真菌外用クリーム組成物
JP3030780B2 (ja) 1988-12-29 2000-04-10 日本農薬株式会社 光学活性なケテンジチオアセタール誘導体及びその製造方法
JPH02264723A (ja) 1989-04-06 1990-10-29 Taisho Pharmaceut Co Ltd 抗真菌剤
AU630469B2 (en) 1989-05-26 1992-10-29 Abbott Laboratories Injectable clarithromycin composition
IL97012A0 (en) 1990-01-30 1992-03-29 Gist Brocades Nv Topical preparations for treating human nails
WO1992002615A1 (en) * 1990-08-09 1992-02-20 Genentech, Inc. Serine protease variants having peptide ligase activity
US5340836A (en) 1991-02-19 1994-08-23 Mark S. Reinhard Composition and method for treatment of vaginal yeast infections
FR2673537B1 (fr) 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
JP2555555B2 (ja) 1991-07-03 1996-11-20 武田薬品工業株式会社 抗真菌性外用製剤
JPH0570351A (ja) 1991-09-17 1993-03-23 Lion Corp 医療用製剤
JPH0665076A (ja) 1992-08-19 1994-03-08 Pola Chem Ind Inc 抗真菌外用剤
JPH06199701A (ja) 1992-12-29 1994-07-19 Lion Corp 外用消炎鎮痛剤
JPH06211651A (ja) 1993-01-12 1994-08-02 Hisamitsu Pharmaceut Co Inc 爪白癬治療用組成物
JPH0774144A (ja) 1993-06-29 1995-03-17 Sony Corp プラズマ装置のクリーニング方法
AU678039B2 (en) 1993-07-01 1997-05-15 Astellas Pharma Europe B.V. Stable topical retinoid compositions
DE4337945A1 (de) 1993-11-06 1995-05-11 Labtec Gmbh Pflaster zur Behandlung von Nagelmykosen
JP2860748B2 (ja) 1993-12-24 1999-02-24 エスエス製薬株式会社 安定な酪酸ヒドロコルチゾン含有クリーム剤
JP3803393B2 (ja) 1994-01-12 2006-08-02 久光製薬株式会社 爪白癬治療用組成物
JP3629283B2 (ja) 1994-02-15 2005-03-16 ポーラ化成工業株式会社 皮膚外用剤
JP3081766B2 (ja) 1994-05-06 2000-08-28 東興薬品工業株式会社 角質貯留型抗真菌外用組成物
JP3522832B2 (ja) 1994-06-21 2004-04-26 ポーラ化成工業株式会社 経皮吸収促進剤及び皮膚外用剤
GB9420355D0 (en) 1994-10-10 1994-11-23 Univ Nottingham Preparation of protein microspheres, films and coatings
AU3673195A (en) 1994-10-13 1996-05-06 Hisamitsu Pharmaceutical Co., Inc. External preparation for nail ringworm
SE9502244D0 (sv) 1995-06-20 1995-06-20 Bioglan Ab A composition and a process for the preparation thereof
ZA965745B (en) 1995-07-08 1997-01-27 Nihon Hohyaku Co Ltd Antifungal agent compound therefor process for producing the same and method for using the same
JP3278738B2 (ja) 1995-07-08 2002-04-30 日本農薬株式会社 抗真菌剤
WO1997007794A1 (fr) 1995-08-28 1997-03-06 Showa Yakuhin Kako Co., Ltd. Composition pour anesthesie locale
US5993787A (en) 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
JP4253047B2 (ja) 1996-09-27 2009-04-08 杏林製薬株式会社 被膜形成性抗真菌剤組成物
JPH10226686A (ja) 1996-12-10 1998-08-25 Nippon Nohyaku Co Ltd 光学活性体である（ｒ）−（ｅ）−（４−置換フェニル−１，３−ジチオラン−２−イリデン）−１−イミダゾールアセトニトリル誘導体及び抗真菌剤及びそれらの製造方法
JP4227677B2 (ja) 1996-12-10 2009-02-18 杏林製薬株式会社 被膜形成性抗真菌剤組成物
RU2189982C2 (ru) * 1997-03-31 2002-09-27 Такеда Кемикал Индастриз, Лтд. Азольные соединения, способ их получения, противогрибковая фармацевтическая композиция и способ лечения грибковой инфекции
AU7936198A (en) 1998-07-01 2000-01-24 Lead Chemical Co., Ltd. Ketotifen preparation for percutaneous absorption
US5962536A (en) 1998-07-31 1999-10-05 Komer; Gene Injectable propofol formulations
CA2343284C (en) 1998-09-10 2008-11-18 Ipr-Institute For Pharmaceutical Research Ag Topical application products
JP2000169372A (ja) 1998-09-29 2000-06-20 Takeda Chem Ind Ltd 抗真菌薬組成物
US20040208906A1 (en) 1999-07-12 2004-10-21 Daiichi Suntory Pharma Co., Ltd. Pharmaceutical composition for topical administration
JP2001064206A (ja) 1999-08-30 2001-03-13 Isp Japan Kk 経皮吸収促進組成物
US7074392B1 (en) 2000-03-27 2006-07-11 Taro Pharmaceutical Industries Limited Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections
US6428654B1 (en) 2000-04-05 2002-08-06 Hercules Incorporated Fungicidal method
JP2002114680A (ja) 2000-07-31 2002-04-16 Nippon Nohyaku Co Ltd 抗真菌剤
JP2002193755A (ja) 2000-12-28 2002-07-10 Sansho Seiyaku Co Ltd フケ・カユミ防止頭髪用および洗髪用化粧料
JP2002284702A (ja) 2001-01-19 2002-10-03 Teika Seiyaku Kk 外用抗真菌製剤
KR100423666B1 (ko) 2001-02-07 2004-03-18 보령제약 주식회사 항진균 외용 제제
US6585963B1 (en) 2001-02-15 2003-07-01 Watson Pharmaceuticals, Inc. Nail compositions and methods of administering same
US20030017207A1 (en) 2001-05-01 2003-01-23 Lin Shun Y. Compositions and methods for treating vulvovaginitis and vaginosis
JP2002363070A (ja) 2001-06-06 2002-12-18 Yuutoku Yakuhin Kogyo Kk 経皮吸収貼付剤
CA2459399C (en) 2001-09-04 2009-06-30 Trommsdorff Gmbh & Co. Kg Arzneimittel Plaster for the treatment of dysfunctions and disorders of nails, comprising sertaconazole
JP2003252798A (ja) 2002-02-28 2003-09-10 Shiseido Co Ltd 抗菌ゲル製剤
WO2003105841A1 (ja) 2002-06-18 2003-12-24 ポーラ化成工業株式会社 抗真菌医薬組成物
US6846837B2 (en) 2002-06-21 2005-01-25 Howard I. Maibach Topical administration of basic antifungal compositions to treat fungal infections of the nails
JP4387639B2 (ja) 2002-07-16 2009-12-16 久光製薬株式会社 経皮吸収製剤
RU2329063C2 (ru) 2002-09-05 2008-07-20 Галдерма С.А. Раствор для применения в области ногтей и околоногтевого пространства
ES2532906T5 (es) 2002-10-25 2022-03-23 Foamix Pharmaceuticals Ltd Espuma cosmética y farmacéutica
ES2366273T3 (es) 2003-03-21 2011-10-18 Nexmed Holdings, Inc. Esmalte de uñas antifúngico y procedimiento de utilización.
CA2522028C (en) 2003-04-10 2011-11-01 Neurogesx, Inc. Methods and compositions for administration of trpv1 agonists
JPWO2005000287A1 (ja) 2003-06-25 2006-10-05 久光製薬株式会社 水虫治療用外用剤
JP2005104924A (ja) * 2003-09-30 2005-04-21 Kobayashi Pharmaceut Co Ltd 外用医薬組成物
JP4431369B2 (ja) * 2003-11-21 2010-03-10 久光製薬株式会社 抗真菌エアゾール外用製剤
JP2005203536A (ja) * 2004-01-15 2005-07-28 Matsushita Electric Ind Co Ltd 光送信器
US20080021098A1 (en) * 2004-02-24 2008-01-24 Givaudan Sa Antifungal Compositions
JP4429035B2 (ja) 2004-02-27 2010-03-10 久光製薬株式会社 角質貯留性を高めた外用クリーム製剤
JP3783104B2 (ja) 2004-03-31 2006-06-07 小林製薬株式会社 抗真菌性外用組成物
US7928144B2 (en) 2004-06-15 2011-04-19 Hisamitsu Pharmaceutical Co., Inc. Antiinflammatory and analgesic preparation for external use
JP4690672B2 (ja) 2004-07-20 2011-06-01 岩城製薬株式会社 乳剤性皮膚外用剤
JP3800232B2 (ja) 2004-09-30 2006-07-26 小林製薬株式会社 抗真菌性外用組成物
JP2006306734A (ja) 2005-04-26 2006-11-09 Tsumura & Co 尿素配合外用剤
US9579297B2 (en) 2005-12-28 2017-02-28 Teikoku Seiyaku Co., Ltd. Pharmaceutical composition for application to nail
NZ571819A (en) 2006-03-08 2011-04-29 Nihon Nohyaku Co Ltd External pharmaceutical composition comprising luliconazole and either N-methyl-2-pyrrolidone, propylene carbonate or crotamiton
US8058303B2 (en) 2006-03-08 2011-11-15 Nihon Nohyaku Co, Ltd Pharmaceutical composition for external use
RU2419429C2 (ru) 2006-03-08 2011-05-27 Нихон Нохияку Ко.,Лтд. Фармацевтическая композиция для наружного применения
WO2008075207A2 (en) 2006-04-04 2008-06-26 Foamix Ltd. Anti-infection augmentation foamable compositions and kit and uses thereof
PL2191828T3 (pl) 2007-09-05 2017-02-28 Pola Pharma Inc. Przeciwgrzybicza kompozycja farmaceutyczna
CN101808637B (zh) 2007-09-05 2013-07-24 宝丽制药股份有限公司 医药组合物
JP5345937B2 (ja) 2007-09-05 2013-11-20 株式会社ポーラファルマ 抗真菌組成物
ES2468540T3 (es) 2009-02-13 2014-06-16 Topica Pharmaceuticals, Inc Formulación antif�ngica
CN102387785B (zh) 2009-04-09 2017-08-25 宝丽制药股份有限公司 抗真菌药物组合物
JP5688406B2 (ja) 2009-04-09 2015-03-25 株式会社ポーラファルマ 抗真菌医薬組成物

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PL2191828T3 (pl) 2017-02-28
JP5453093B2 (ja) 2014-03-26
EP2191828B1 (en) 2016-08-10
US20100168200A1 (en) 2010-07-01
CN101808639A (zh) 2010-08-18
EP2191828A1 (en) 2010-06-02
US9480678B2 (en) 2016-11-01
KR20100068271A (ko) 2010-06-22
JPWO2009031644A1 (ja) 2010-12-16
EP2191828A4 (en) 2010-09-15
ES2591030T3 (es) 2016-11-24
WO2009031644A1 (ja) 2009-03-12
CN101808639B (zh) 2012-12-05

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