HRP20171425T1 - Derivati oksazolidin-2-on-pirimidina - Google Patents

Derivati oksazolidin-2-on-pirimidina Download PDF

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Publication number
HRP20171425T1
HRP20171425T1 HRP20171425TT HRP20171425T HRP20171425T1 HR P20171425 T1 HRP20171425 T1 HR P20171425T1 HR P20171425T T HRP20171425T T HR P20171425TT HR P20171425 T HRP20171425 T HR P20171425T HR P20171425 T1 HRP20171425 T1 HR P20171425T1
Authority
HR
Croatia
Prior art keywords
alkoxy
trifluoromethyl
amino
oxazolidin
compound according
Prior art date
Application number
HRP20171425TT
Other languages
English (en)
Croatian (hr)
Inventor
Robin Alec Fairhurst
Pascal Furet
Frank Stephan Kalthoff
Andreas Lerchner
Heinrich Rueeger
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HRP20171425T1 publication Critical patent/HRP20171425T1/hr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HRP20171425TT 2012-11-12 2013-11-11 Derivati oksazolidin-2-on-pirimidina HRP20171425T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261725113P 2012-11-12 2012-11-12
PCT/IB2013/060052 WO2014072956A1 (en) 2012-11-12 2013-11-11 Oxazolidin-2-one-pyrimidine derivatives
EP13795867.4A EP2922848B1 (en) 2012-11-12 2013-11-11 Oxazolidin-2-one-pyrimidine derivatives

Publications (1)

Publication Number Publication Date
HRP20171425T1 true HRP20171425T1 (hr) 2017-11-17

Family

ID=49667527

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20171425TT HRP20171425T1 (hr) 2012-11-12 2013-11-11 Derivati oksazolidin-2-on-pirimidina

Country Status (42)

Country Link
US (3) US9296733B2 (enExample)
EP (2) EP3199158B1 (enExample)
JP (1) JP6262245B2 (enExample)
KR (1) KR102153763B1 (enExample)
CN (1) CN104718204B (enExample)
AP (1) AP2015008347A0 (enExample)
AR (1) AR093408A1 (enExample)
AU (1) AU2013343022B2 (enExample)
BR (1) BR112015010136A2 (enExample)
CA (1) CA2890942C (enExample)
CL (1) CL2015001202A1 (enExample)
CO (1) CO7380758A2 (enExample)
CR (1) CR20150248A (enExample)
CU (1) CU24365B1 (enExample)
CY (1) CY1119391T1 (enExample)
DK (1) DK2922848T5 (enExample)
EA (2) EA029714B1 (enExample)
EC (1) ECSP15025093A (enExample)
ES (1) ES2641820T3 (enExample)
HR (1) HRP20171425T1 (enExample)
HU (1) HUE034492T2 (enExample)
IL (1) IL238239A (enExample)
IN (1) IN2015DN02912A (enExample)
JO (1) JO3334B1 (enExample)
LT (1) LT2922848T (enExample)
MA (1) MA38076A1 (enExample)
MX (1) MX363436B (enExample)
MY (1) MY174239A (enExample)
NZ (1) NZ706591A (enExample)
PE (1) PE20151006A1 (enExample)
PH (1) PH12015501053A1 (enExample)
PL (1) PL2922848T3 (enExample)
PT (1) PT2922848T (enExample)
RS (1) RS56336B1 (enExample)
SG (1) SG11201503447QA (enExample)
SI (1) SI2922848T1 (enExample)
TN (1) TN2015000120A1 (enExample)
TW (1) TWI608005B (enExample)
UA (1) UA114001C2 (enExample)
UY (1) UY35128A (enExample)
WO (1) WO2014072956A1 (enExample)
ZA (1) ZA201502175B (enExample)

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JP6026544B2 (ja) 2011-09-27 2016-11-16 ノバルティス アーゲー 変異体idhの阻害剤としての3−ピリミジン−4−イル−オキサゾリジン−2−オン類
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HK1213251A1 (zh) 2013-03-14 2016-06-30 Novartis Ag 作为突变idh抑制剂的3-嘧啶-4-基-恶唑烷-2-酮化合物
KR20180081501A (ko) 2015-09-24 2018-07-16 드렉셀유니버시티 진피 장애를 치료하거나 예방하는 신규한 조성물 및 방법
MX2018014167A (es) 2016-05-18 2019-08-16 Piqur Therapeutics Ag Tratamiento de lesiones de la piel.
WO2017198347A1 (en) * 2016-05-18 2017-11-23 Piqur Therapeutics Ag Treatment of skin lesions
TW201929861A (zh) 2017-11-06 2019-08-01 瑞士商諾華公司 包含㗁唑啶-2-酮-嘧啶衍生物之調配物
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