HRP20160685T1 - Pripravci koji sadrže pneumokokne antigene - Google Patents
Pripravci koji sadrže pneumokokne antigene Download PDFInfo
- Publication number
- HRP20160685T1 HRP20160685T1 HRP20160685TT HRP20160685T HRP20160685T1 HR P20160685 T1 HRP20160685 T1 HR P20160685T1 HR P20160685T T HRP20160685T T HR P20160685TT HR P20160685 T HRP20160685 T HR P20160685T HR P20160685 T1 HRP20160685 T1 HR P20160685T1
- Authority
- HR
- Croatia
- Prior art keywords
- seq
- antigen
- acid sequence
- amino acid
- epitope
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title claims 60
- 102000036639 antigens Human genes 0.000 title claims 60
- 108091007433 antigens Proteins 0.000 title claims 60
- 239000000203 mixture Substances 0.000 title claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 32
- 150000001413 amino acids Chemical class 0.000 claims 25
- 239000012634 fragment Substances 0.000 claims 25
- 229920001184 polypeptide Polymers 0.000 claims 9
- 102000004196 processed proteins & peptides Human genes 0.000 claims 9
- 108090000765 processed proteins & peptides Proteins 0.000 claims 9
- 150000001720 carbohydrates Chemical class 0.000 claims 8
- 230000002163 immunogen Effects 0.000 claims 7
- 241000588650 Neisseria meningitidis Species 0.000 claims 4
- 241000894006 Bacteria Species 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 2
- 241000606768 Haemophilus influenzae Species 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 2
- 101100289918 Streptococcus pneumoniae (strain ATCC BAA-255 / R6) lytB gene Proteins 0.000 claims 2
- 101100312899 Streptococcus pneumoniae (strain ATCC BAA-255 / R6) ply gene Proteins 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 231100000699 Bacterial toxin Toxicity 0.000 claims 1
- 102100037840 Dehydrogenase/reductase SDR family member 2, mitochondrial Human genes 0.000 claims 1
- 241000991587 Enterovirus C Species 0.000 claims 1
- 241000700721 Hepatitis B virus Species 0.000 claims 1
- 201000005702 Pertussis Diseases 0.000 claims 1
- 208000035109 Pneumococcal Infections Diseases 0.000 claims 1
- 101710188053 Protein D Proteins 0.000 claims 1
- 101710132893 Resolvase Proteins 0.000 claims 1
- 239000000688 bacterial toxin Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 229960003983 diphtheria toxoid Drugs 0.000 claims 1
- 231100000676 disease causative agent Toxicity 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 239000011814 protection agent Substances 0.000 claims 1
- 229960000814 tetanus toxoid Drugs 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0714963.6A GB0714963D0 (en) | 2007-08-01 | 2007-08-01 | Compositions comprising antigens |
| US96686607P | 2007-08-29 | 2007-08-29 | |
| EP12197549.4A EP2572726B1 (en) | 2007-08-01 | 2008-08-01 | Compositions comprising pneumococcal antigens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20160685T1 true HRP20160685T1 (hr) | 2016-07-15 |
Family
ID=38529101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20160685TT HRP20160685T1 (hr) | 2007-08-01 | 2016-06-16 | Pripravci koji sadrže pneumokokne antigene |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US20110243976A1 (enExample) |
| EP (2) | EP2572726B1 (enExample) |
| JP (2) | JP2010535025A (enExample) |
| CN (2) | CN104001165B (enExample) |
| AP (1) | AP2010005173A0 (enExample) |
| AU (1) | AU2008281438A1 (enExample) |
| BR (1) | BRPI0813892A2 (enExample) |
| CA (1) | CA2695169A1 (enExample) |
| CO (1) | CO6260103A2 (enExample) |
| CY (1) | CY1117689T1 (enExample) |
| DK (1) | DK2572726T3 (enExample) |
| EA (1) | EA018137B1 (enExample) |
| ES (1) | ES2580957T3 (enExample) |
| GB (1) | GB0714963D0 (enExample) |
| HR (1) | HRP20160685T1 (enExample) |
| HU (1) | HUE029670T2 (enExample) |
| PL (1) | PL2572726T3 (enExample) |
| PT (1) | PT2572726T (enExample) |
| SI (1) | SI2572726T1 (enExample) |
| WO (1) | WO2009016515A2 (enExample) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| HUE045482T2 (hu) | 2005-06-27 | 2019-12-30 | Glaxosmithkline Biologicals Sa | Immunogén készítmény |
| AU2009226949A1 (en) | 2008-03-17 | 2009-09-24 | Intercell Ag | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| ATE523204T1 (de) | 2009-02-16 | 2011-09-15 | Karlsruher Inst Technologie | Cd44v6-peptide als bakterielle infektionsinhibitoren |
| ES2531115T3 (es) * | 2009-06-01 | 2015-03-10 | Novartis Ag | Combinaciones de clados de RrgB neumocócicos |
| JP5931724B2 (ja) | 2009-06-29 | 2016-06-08 | ジェノセア バイオサイエンシーズ， インコーポレイテッド | ＳｔｒｅｐｔｏｃｏｃｃｕｓＰｎｅｕｍｏｎｉａｅに対するワクチンおよび組成物 |
| CN102695523A (zh) * | 2009-09-10 | 2012-09-26 | 诺华有限公司 | 针对呼吸道疾病的组合疫苗 |
| WO2011075822A1 (en) * | 2009-12-22 | 2011-06-30 | Sanofi Pasteur Limited | Immunogenic compositions and related methods |
| JP2013525271A (ja) | 2010-03-12 | 2013-06-20 | チルドレンズ メディカル センター コーポレーション | 免疫原およびそのスクリーニング方法 |
| GB201005625D0 (en) | 2010-04-01 | 2010-05-19 | Novartis Ag | Immunogenic proteins and compositions |
| FI4005592T3 (fi) | 2010-07-06 | 2023-01-13 | Virionin kaltaisia kuljetuspartikkeleita itsereplikoituville rna-molekyyleille | |
| PT3243526T (pt) | 2010-07-06 | 2020-03-04 | Glaxosmithkline Biologicals Sa | Distribuição de arn para despoletar múltiplas vias imunitárias |
| US9770463B2 (en) | 2010-07-06 | 2017-09-26 | Glaxosmithkline Biologicals Sa | Delivery of RNA to different cell types |
| US10487332B2 (en) | 2010-07-06 | 2019-11-26 | Glaxosmithkline Biologicals Sa | Immunisation of large mammals with low doses of RNA |
| CN103153284B (zh) | 2010-07-06 | 2015-11-25 | 诺华股份有限公司 | 含有其pKa值有利于RNA递送的脂质的脂质体 |
| US9192661B2 (en) | 2010-07-06 | 2015-11-24 | Novartis Ag | Delivery of self-replicating RNA using biodegradable polymer particles |
| CA2808975C (en) | 2010-08-23 | 2018-10-30 | Wyeth Llc | Stable formulations of neisseria meningitidis rlp2086 antigens |
| JP5911870B2 (ja) | 2010-08-31 | 2016-04-27 | ノバルティス アーゲー | 免疫原をコードするｒｎａの送達のためのｐｅｇ化リポソーム |
| EP3542789A3 (en) | 2010-08-31 | 2020-01-01 | GlaxoSmithKline Biologicals SA | Lipids suitable for liposomal delivery of protein-coding rna |
| KR101584871B1 (ko) * | 2010-09-10 | 2016-01-22 | 와이어쓰 엘엘씨 | 네이세리아 메닝기티디스 orf2086 항원의 비-지질화된 변이체 |
| KR102266691B1 (ko) | 2010-10-11 | 2021-06-23 | 노파르티스 아게 | 항원 전달 플랫폼 |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| SG10201600435UA (en) * | 2011-01-20 | 2016-02-26 | Genocea Biosciences Inc | Vaccines And Compositions Against Streptococcus Pneumoniae |
| CN107320734A (zh) * | 2011-04-29 | 2017-11-07 | 西莱克塔生物科技公司 | 从合成纳米载体中控制释放免疫抑制剂 |
| RU2632651C2 (ru) | 2011-05-11 | 2017-10-06 | Чилдрен'С Медикал Сентер Корпорейшн | Модифицированный биотин-связывающий белок, слитые белки на его основе и их применение |
| RU2014104090A (ru) | 2011-07-06 | 2015-08-20 | Новартис Аг | Липосомы с эффективным соотношением n:p для доставки молекул phk |
| JP2014522842A (ja) | 2011-07-06 | 2014-09-08 | ノバルティス アーゲー | 免疫原性組み合わせ組成物およびその使用 |
| PT2750707T (pt) | 2011-08-31 | 2019-01-23 | Glaxosmithkline Biologicals Sa | Lipossomas peguilados para distribuição de arn que codifica imunogénio |
| CA2851270C (en) * | 2011-10-05 | 2023-03-14 | The Rockefeller University | Dimeric bacteriophage lysins |
| RU2636350C2 (ru) * | 2011-11-07 | 2017-11-22 | Новартис Аг | МОЛЕКУЛА, СОДЕРЖАЩАЯ SPR0096 и SPR2021 |
| WO2013131983A1 (en) | 2012-03-07 | 2013-09-12 | Novartis Ag | Adjuvanted formulations of streptococcus pneumoniae antigens |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| CA2865745C (en) | 2012-03-09 | 2018-01-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| KR102057217B1 (ko) | 2012-06-20 | 2020-01-22 | 에스케이바이오사이언스 주식회사 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
| AU2013320313B2 (en) | 2012-09-18 | 2018-07-12 | Glaxosmithkline Biologicals Sa | Outer membrane vesicles |
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| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
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| EA201790551A1 (ru) | 2014-09-07 | 2017-07-31 | Селекта Байосайенсиз, Инк. | Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору |
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2007
- 2007-08-01 GB GBGB0714963.6A patent/GB0714963D0/en not_active Ceased
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2008
- 2008-08-01 AU AU2008281438A patent/AU2008281438A1/en not_active Abandoned
- 2008-08-01 CN CN201410192895.3A patent/CN104001165B/zh not_active Expired - Fee Related
- 2008-08-01 WO PCT/IB2008/002866 patent/WO2009016515A2/en not_active Ceased
- 2008-08-01 ES ES12197549.4T patent/ES2580957T3/es active Active
- 2008-08-01 AP AP2010005173A patent/AP2010005173A0/en unknown
- 2008-08-01 PT PT121975494T patent/PT2572726T/pt unknown
- 2008-08-01 JP JP2010518777A patent/JP2010535025A/ja active Pending
- 2008-08-01 PL PL12197549.4T patent/PL2572726T3/pl unknown
- 2008-08-01 EP EP12197549.4A patent/EP2572726B1/en active Active
- 2008-08-01 EP EP08826694A patent/EP2197484A2/en not_active Withdrawn
- 2008-08-01 HU HUE12197549A patent/HUE029670T2/en unknown
- 2008-08-01 CA CA2695169A patent/CA2695169A1/en not_active Abandoned
- 2008-08-01 SI SI200831646A patent/SI2572726T1/sl unknown
- 2008-08-01 DK DK12197549.4T patent/DK2572726T3/en active
- 2008-08-01 BR BRPI0813892A patent/BRPI0813892A2/pt not_active IP Right Cessation
- 2008-08-01 CN CN200880108017A patent/CN101801409A/zh active Pending
- 2008-08-01 US US12/733,010 patent/US20110243976A1/en not_active Abandoned
- 2008-08-01 EA EA201070200A patent/EA018137B1/ru not_active IP Right Cessation
-
2010
- 2010-03-01 CO CO10023973A patent/CO6260103A2/es not_active Application Discontinuation
-
2013
- 2013-11-06 JP JP2013230378A patent/JP5838193B2/ja not_active Expired - Fee Related
-
2014
- 2014-06-06 US US14/298,764 patent/US20140348868A1/en not_active Abandoned
-
2016
- 2016-06-16 HR HRP20160685TT patent/HRP20160685T1/hr unknown
- 2016-06-28 CY CY20161100580T patent/CY1117689T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB0714963D0 (en) | 2007-09-12 |
| EP2572726A1 (en) | 2013-03-27 |
| WO2009016515A3 (en) | 2009-08-13 |
| HUE029670T2 (en) | 2017-03-28 |
| CN104001165B (zh) | 2018-08-14 |
| JP2014034578A (ja) | 2014-02-24 |
| PL2572726T3 (pl) | 2016-12-30 |
| PT2572726T (pt) | 2016-08-05 |
| DK2572726T3 (en) | 2016-07-04 |
| AP2010005173A0 (en) | 2010-02-28 |
| AU2008281438A1 (en) | 2009-02-05 |
| ES2580957T3 (es) | 2016-08-30 |
| EP2572726B1 (en) | 2016-05-04 |
| JP5838193B2 (ja) | 2016-01-06 |
| JP2010535025A (ja) | 2010-11-18 |
| US20140348868A1 (en) | 2014-11-27 |
| EA018137B1 (ru) | 2013-05-30 |
| BRPI0813892A2 (pt) | 2017-05-09 |
| CA2695169A1 (en) | 2009-02-05 |
| CN104001165A (zh) | 2014-08-27 |
| WO2009016515A2 (en) | 2009-02-05 |
| CO6260103A2 (es) | 2011-03-22 |
| CY1117689T1 (el) | 2017-05-17 |
| CN101801409A (zh) | 2010-08-11 |
| SI2572726T1 (sl) | 2016-08-31 |
| US20110243976A1 (en) | 2011-10-06 |
| EA201070200A1 (ru) | 2010-08-30 |
| EP2197484A2 (en) | 2010-06-23 |
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