JP2020533442A5 - - Google Patents
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- JP2020533442A5 JP2020533442A5 JP2020513626A JP2020513626A JP2020533442A5 JP 2020533442 A5 JP2020533442 A5 JP 2020533442A5 JP 2020513626 A JP2020513626 A JP 2020513626A JP 2020513626 A JP2020513626 A JP 2020513626A JP 2020533442 A5 JP2020533442 A5 JP 2020533442A5
- Authority
- JP
- Japan
- Prior art keywords
- polysaccharide
- immunogenic composition
- composition according
- protein conjugate
- adjuvant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023009333A JP7519478B2 (ja) | 2017-09-07 | 2023-01-25 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
| JP2024109504A JP2024133653A (ja) | 2017-09-07 | 2024-07-08 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762555479P | 2017-09-07 | 2017-09-07 | |
| US62/555,479 | 2017-09-07 | ||
| PCT/US2018/049309 WO2019050816A1 (en) | 2017-09-07 | 2018-09-04 | ANTI-PNEUMOCOCCAL POLYSACCHARIDES AND THEIR USE IN IMMUNOGENIC CONJUGATES POLYSACCHARIDE-PROTEIN CARRIER |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009333A Division JP7519478B2 (ja) | 2017-09-07 | 2023-01-25 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020533442A JP2020533442A (ja) | 2020-11-19 |
| JP2020533442A5 true JP2020533442A5 (enExample) | 2021-08-19 |
| JP7218358B2 JP7218358B2 (ja) | 2023-02-06 |
Family
ID=65634538
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020513626A Active JP7218358B2 (ja) | 2017-09-07 | 2018-09-04 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
| JP2023009333A Active JP7519478B2 (ja) | 2017-09-07 | 2023-01-25 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
| JP2024109504A Pending JP2024133653A (ja) | 2017-09-07 | 2024-07-08 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023009333A Active JP7519478B2 (ja) | 2017-09-07 | 2023-01-25 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
| JP2024109504A Pending JP2024133653A (ja) | 2017-09-07 | 2024-07-08 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11389540B2 (enExample) |
| EP (1) | EP3678652A4 (enExample) |
| JP (3) | JP7218358B2 (enExample) |
| KR (1) | KR102736151B1 (enExample) |
| CN (2) | CN111065387B (enExample) |
| AU (2) | AU2018328038B2 (enExample) |
| BR (1) | BR112020004502A8 (enExample) |
| CA (1) | CA3074711A1 (enExample) |
| MX (2) | MX394767B (enExample) |
| WO (1) | WO2019050816A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| IL267709B2 (en) | 2016-12-30 | 2025-04-01 | Vaxcyte Inc | Polypeptide-antigen conjugates with unnatural amino acids |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| WO2018144439A1 (en) | 2017-01-31 | 2018-08-09 | Merck Sharp & Dohme Corp. | Methods for making polysaccharide-protein conjugates |
| JP7680185B2 (ja) * | 2017-02-24 | 2025-05-20 | メルク・シャープ・アンド・ドーム・エルエルシー | 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強 |
| US11400162B2 (en) | 2017-02-24 | 2022-08-02 | Merck Sharp & Dohme Llc | Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein |
| WO2019050818A1 (en) | 2017-09-07 | 2019-03-14 | Merck Sharp & Dohme Corp. | METHODS OF FORMULATING PNEUMOCOCCAL POLYSACCHARIDES FOR CONJUGATION TO A CARRIER PROTEIN |
| US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
| US11395849B2 (en) | 2017-09-07 | 2022-07-26 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| CA3074706A1 (en) * | 2017-09-07 | 2019-03-14 | Merck Sharp & Dohme Corp. | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| US11524076B2 (en) | 2017-09-07 | 2022-12-13 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| HUE068482T2 (hu) * | 2017-09-07 | 2025-01-28 | Merck Sharp & Dohme Llc | Pneumococcus-poliszacharidok és azok felhasználása immunogén poliszacharid-hordozóprotein konjugátumokban |
| CN111065387B (zh) | 2017-09-07 | 2023-08-25 | 默沙东有限责任公司 | 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途 |
| EP3691677A4 (en) * | 2017-10-04 | 2021-07-07 | Pogona, Llc | COMPOSITIONS OF SACCHARIDE-POLYPEPTIDE CONJUGATES AND THEIR METHODS OF USE |
| EP3720483B1 (en) | 2017-12-06 | 2025-11-19 | Merck Sharp & Dohme LLC | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
| BR112020015696A2 (pt) | 2018-02-05 | 2020-12-08 | Sanofi Pasteur, Inc. | Composição de conjugado polissacarídeo-proteína pneumocócico multivalente |
| TW202011985A (zh) | 2018-04-18 | 2020-04-01 | 韓商Ｓｋ生物科學股份有限公司 | 肺炎鏈球菌的莢膜多醣類以及其免疫原性接合體 |
| WO2019212846A1 (en) | 2018-04-30 | 2019-11-07 | Merck Sharp & Dohme Corp. | Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates |
| JP7397000B2 (ja) | 2018-04-30 | 2023-12-12 | メルク・シャープ・アンド・ドーム・エルエルシー | 凍結乾燥変異ジフテリア毒素のジメチルスルホキシド中均一溶液を提供する方法 |
| WO2019212842A1 (en) | 2018-04-30 | 2019-11-07 | Merck Sharp & Dohme Corp. | Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates from lyospheres |
| MX2021003358A (es) | 2018-09-23 | 2021-05-27 | Biological E Ltd | Polisacaridos capsulares purificados de streptococcus pneumoniae. |
| EP3897705A2 (en) | 2018-12-19 | 2021-10-27 | Merck Sharp & Dohme Corp. | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
Family Cites Families (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2059693C (en) * | 1991-01-28 | 2003-08-19 | Peter J. Kniskern | Polysaccharide antigens from streptococcus pneumoniae |
| CA2059692C (en) | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| GB0220198D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Modified saccharides,conjugates thereof and their manufacture |
| AU2003901717A0 (en) * | 2003-04-10 | 2003-05-01 | Western Sydney Area Health Service | Identification of streptococcus pneumoniae serotypes |
| GB0313250D0 (en) * | 2003-06-09 | 2003-07-16 | Angeletti P Ist Richerche Bio | Therapeutic agents |
| US20080219960A1 (en) | 2004-12-16 | 2008-09-11 | Masja Nathalie Nierop Groot | Novel Efficient Production Process for Capsular Polysaccharides of Pathogenic Grampositive Bacteria by Heterologous Expression and Secretion of Complex Polysaccharides in Non-Pathogenic, Non-Invasive Gram-Positive Bacteria |
| CA2597489A1 (en) | 2005-02-11 | 2006-08-17 | Ace Biosciences A/S | Surface-located streptococcus pneumoniae polypeptides |
| US7955605B2 (en) | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US20070184072A1 (en) | 2005-04-08 | 2007-08-09 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| IL308456A (en) | 2005-04-08 | 2024-01-01 | Wyeth Llc | A multivalent pneumomuroral protein-polysaccharide conjugate preparation |
| PL1866342T3 (pl) | 2005-04-08 | 2019-04-30 | Wyeth Llc | Oddzielanie zanieczyszczeń od polisacharydu Streptococcus pneumoniae przez manipulację pH |
| US7709001B2 (en) * | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| HUE045482T2 (hu) | 2005-06-27 | 2019-12-30 | Glaxosmithkline Biologicals Sa | Immunogén készítmény |
| JP5792920B2 (ja) | 2005-12-22 | 2015-10-14 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| JP5285431B2 (ja) | 2005-12-28 | 2013-09-11 | ザ ユーエイビー リサーチ ファウンデイション | 肺炎球菌血清型 |
| TW200806315A (en) | 2006-04-26 | 2008-02-01 | Wyeth Corp | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
| US8808707B1 (en) | 2006-05-08 | 2014-08-19 | Wyeth Llc | Pneumococcal dosing regimen |
| CA2665169C (en) | 2006-10-10 | 2017-02-21 | Wyeth | Purification of streptococcus pneumoniae type 3 polysaccharides |
| HUE039169T2 (hu) | 2007-03-23 | 2018-12-28 | Wyeth Llc | Rövidített tisztítási eljárás Streptococcus pneumoniae tok-poliszacharidok elõállítására |
| DK2162546T3 (en) | 2007-05-29 | 2019-01-21 | Uab Res Found | PNEUMOKOK SEROTYPE 6D |
| US8540955B2 (en) | 2007-07-10 | 2013-09-24 | Wyeth Llc | Process for producing aluminum phosphate |
| CA2744588A1 (en) | 2008-11-26 | 2010-06-03 | Glaxo Group Limited | Ligands that bind il-13 |
| EP2385981B1 (en) | 2008-12-18 | 2019-09-04 | Wyeth LLC | Method for controlling streptococcus pneumoniae polysaccharide molecular weight using carbon |
| WO2010080486A2 (en) * | 2008-12-18 | 2010-07-15 | Wyeth Llc | Method for controlling streptococcus pneumoniae serotype 19a polysaccharide molecular weight |
| WO2010088222A2 (en) | 2009-01-27 | 2010-08-05 | World Force Technologies, Llc | A high molecular weight polysaccharide that binds and inhibits virus |
| WO2011041003A2 (en) | 2009-06-22 | 2011-04-07 | Wyeth Llc | Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions |
| US8748123B2 (en) | 2009-12-15 | 2014-06-10 | 73100-Setenta e Tres Mil e Cem, Lda. | Fucose-containing bacterial biopolymer |
| TW201136603A (en) | 2010-02-09 | 2011-11-01 | Merck Sharp & Amp Dohme Corp | 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition |
| EP3626263A1 (en) | 2010-06-04 | 2020-03-25 | Wyeth LLC | Vaccine formulations |
| US20130273098A1 (en) | 2010-12-10 | 2013-10-17 | Jeffrey T. Blue | Novel formulations which mitigate agitation-induced aggregation of immunogenic compositions |
| PL2526951T3 (pl) | 2011-05-27 | 2016-04-29 | Univ Freiburg | Ramno-polisacharyd z kompleksu klonalnego 17 Enterococcus faecium i jego zastosowania |
| KR101675657B1 (ko) | 2012-03-19 | 2016-11-11 | 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. | 탄수화물-당지질 컨쥬게이트 백신 |
| KR102057217B1 (ko) | 2012-06-20 | 2020-01-22 | 에스케이바이오사이언스 주식회사 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
| KR20140075201A (ko) | 2012-12-11 | 2014-06-19 | 에스케이케미칼주식회사 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
| RU2672053C2 (ru) | 2012-12-20 | 2018-11-09 | Пфайзер Инк. | Способ гликоконъюгации |
| BR112016015835B1 (pt) | 2014-01-21 | 2023-12-26 | Pfizer Inc | Processo de preparação de conjugados compreendendo polissacarídeos capsulares de streptococcus pneumoniae |
| IL312327B2 (en) | 2014-01-21 | 2026-02-01 | Pfizer | Immunogenic preparations comprising conjugated capsular saccharide antigens and their uses |
| FI3583947T3 (fi) | 2014-01-21 | 2023-10-12 | Pfizer | Streptococcus pneumoniaen kapselipolysakkaridit ja niiden konjugaatit |
| AR104469A1 (es) | 2014-08-08 | 2017-07-26 | Glycovaxyn Ag | Células huésped modificadas para su uso en producción de bioconjugados |
| PL3244917T3 (pl) | 2015-01-15 | 2023-07-17 | Pfizer Inc. | Kompozycje immunogenne do zastosowania w szczepionkach przeciwko pneumokokom |
| KR102143534B1 (ko) | 2015-05-04 | 2020-08-12 | 화이자 인코포레이티드 | B군 스트렙토코쿠스 폴리사카라이드-단백질 접합체, 접합체를 생산하는 방법, 접합체를 포함하는 면역원성 조성물, 및 그의 용도 |
| KR20250058066A (ko) | 2015-07-21 | 2025-04-29 | 화이자 인코포레이티드 | 접합된 캡슐형 사카라이드 항원을 포함하는 면역원성 조성물, 그를 포함하는 키트 및 그의 용도 |
| IL259404B2 (en) | 2015-11-17 | 2025-08-01 | Pfizer | Media and fermentation methods for producing polysaccharides in bacterial cell culture |
| US10786561B2 (en) | 2015-11-20 | 2020-09-29 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| US11058757B2 (en) | 2016-03-31 | 2021-07-13 | Pogona, LLC | Saccharide-polypeptide conjugate compositions and methods of use thereof |
| EP3493837B1 (en) | 2016-08-05 | 2022-08-31 | Sanofi Pasteur, Inc. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| IL267709B2 (en) | 2016-12-30 | 2025-04-01 | Vaxcyte Inc | Polypeptide-antigen conjugates with unnatural amino acids |
| BR112019014833A2 (pt) | 2017-01-20 | 2020-04-14 | Pfizer | composições imunogênicas para uso em vacinas pneumococais |
| WO2018144439A1 (en) | 2017-01-31 | 2018-08-09 | Merck Sharp & Dohme Corp. | Methods for making polysaccharide-protein conjugates |
| CN110225757A (zh) | 2017-01-31 | 2019-09-10 | 默沙东公司 | 由肺炎链球菌血清型19f生产荚膜多糖蛋白缀合物的方法 |
| JP7680185B2 (ja) | 2017-02-24 | 2025-05-20 | メルク・シャープ・アンド・ドーム・エルエルシー | 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強 |
| CN110392690B (zh) | 2017-02-24 | 2024-01-30 | 默沙东有限责任公司 | 肺炎球菌缀合物疫苗制剂 |
| US20200061542A1 (en) | 2017-02-24 | 2020-02-27 | Merck Sharp & Dohme Corp. | Methods for improving filterability of polysaccharide-protein conjugate reactions |
| WO2019050818A1 (en) | 2017-09-07 | 2019-03-14 | Merck Sharp & Dohme Corp. | METHODS OF FORMULATING PNEUMOCOCCAL POLYSACCHARIDES FOR CONJUGATION TO A CARRIER PROTEIN |
| US11219680B2 (en) | 2017-02-24 | 2022-01-11 | Merck Sharp & Dohme Corp. | Polysaccharide-protein conjugates utilizing diphtheria toxin fragment B as a carrier |
| WO2019036313A1 (en) | 2017-08-16 | 2019-02-21 | Merck Sharp & Dohme Corp. | CONJUGATED PNEUMOCOCCAL VACCINE FORMULATIONS |
| CA3074706A1 (en) | 2017-09-07 | 2019-03-14 | Merck Sharp & Dohme Corp. | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| HUE068482T2 (hu) | 2017-09-07 | 2025-01-28 | Merck Sharp & Dohme Llc | Pneumococcus-poliszacharidok és azok felhasználása immunogén poliszacharid-hordozóprotein konjugátumokban |
| US11395849B2 (en) | 2017-09-07 | 2022-07-26 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| CN111065387B (zh) | 2017-09-07 | 2023-08-25 | 默沙东有限责任公司 | 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途 |
| WO2019083865A1 (en) | 2017-10-25 | 2019-05-02 | Merck Sharp & Dohme Corp. | VACCINES WITH ADJUVANT |
| EP3720483B1 (en) | 2017-12-06 | 2025-11-19 | Merck Sharp & Dohme LLC | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
| WO2019212846A1 (en) | 2018-04-30 | 2019-11-07 | Merck Sharp & Dohme Corp. | Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates |
| JP7397000B2 (ja) | 2018-04-30 | 2023-12-12 | メルク・シャープ・アンド・ドーム・エルエルシー | 凍結乾燥変異ジフテリア毒素のジメチルスルホキシド中均一溶液を提供する方法 |
| WO2019212842A1 (en) | 2018-04-30 | 2019-11-07 | Merck Sharp & Dohme Corp. | Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates from lyospheres |
| EP3801469A4 (en) | 2018-06-07 | 2022-03-09 | Merck Sharp & Dohme Corp. | CRITICAL LYOSPHERE REAGENTS KIT |
| US20220016229A1 (en) | 2018-12-12 | 2022-01-20 | Pfizer Inc. | Immunogenic Multiple Hetero-Antigen Polysaccharide-Protein Conjugates and uses thereof |
| EP3897705A2 (en) | 2018-12-19 | 2021-10-27 | Merck Sharp & Dohme Corp. | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
| US20220184199A1 (en) | 2019-04-10 | 2022-06-16 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof |
| CA3142692A1 (en) | 2019-06-05 | 2020-12-10 | Merck Sharp & Dohme Corp. | An immunogenic serotype 35b pneumococcal polysaccharide-protein conjugate and conjugation process for making the same |
| MX2021014948A (es) | 2019-06-05 | 2022-01-24 | Merck Sharp & Dohme Llc | Metodos de tratamiento de pacientes con una composicion inmunogenica que protege contra el seroripo 29 de s. pneumoniae. |
-
2018
- 2018-09-04 CN CN201880058214.0A patent/CN111065387B/zh active Active
- 2018-09-04 CN CN202311033166.9A patent/CN117018172A/zh active Pending
- 2018-09-04 EP EP18852846.7A patent/EP3678652A4/en active Pending
- 2018-09-04 BR BR112020004502A patent/BR112020004502A8/pt unknown
- 2018-09-04 US US16/645,080 patent/US11389540B2/en active Active
- 2018-09-04 WO PCT/US2018/049309 patent/WO2019050816A1/en not_active Ceased
- 2018-09-04 MX MX2020002556A patent/MX394767B/es unknown
- 2018-09-04 AU AU2018328038A patent/AU2018328038B2/en active Active
- 2018-09-04 JP JP2020513626A patent/JP7218358B2/ja active Active
- 2018-09-04 CA CA3074711A patent/CA3074711A1/en active Pending
- 2018-09-04 KR KR1020207009615A patent/KR102736151B1/ko active Active
-
2020
- 2020-03-05 MX MX2022009928A patent/MX2022009928A/es unknown
-
2022
- 2022-06-24 US US17/848,462 patent/US11964023B2/en active Active
- 2022-06-24 US US17/848,456 patent/US11759523B2/en active Active
-
2023
- 2023-01-25 JP JP2023009333A patent/JP7519478B2/ja active Active
-
2024
- 2024-03-07 AU AU2024201517A patent/AU2024201517B2/en not_active Expired - Fee Related
- 2024-07-08 JP JP2024109504A patent/JP2024133653A/ja active Pending
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