JP2018516962A5 - - Google Patents

Download PDF

Info

Publication number
JP2018516962A5
JP2018516962A5 JP2017564108A JP2017564108A JP2018516962A5 JP 2018516962 A5 JP2018516962 A5 JP 2018516962A5 JP 2017564108 A JP2017564108 A JP 2017564108A JP 2017564108 A JP2017564108 A JP 2017564108A JP 2018516962 A5 JP2018516962 A5 JP 2018516962A5
Authority
JP
Japan
Prior art keywords
polysaccharide
protein
conjugate
composition
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017564108A
Other languages
English (en)
Japanese (ja)
Other versions
JP7258463B2 (ja
JP2018516962A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2016/053265 external-priority patent/WO2016199003A1/en
Publication of JP2018516962A publication Critical patent/JP2018516962A/ja
Publication of JP2018516962A5 publication Critical patent/JP2018516962A5/ja
Priority to JP2021129726A priority Critical patent/JP2021185152A/ja
Application granted granted Critical
Publication of JP7258463B2 publication Critical patent/JP7258463B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017564108A 2015-06-08 2016-06-03 多糖-タンパク質結合体の吸着およびそれから得られた多価のワクチン製剤を改善するための方法 Active JP7258463B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021129726A JP2021185152A (ja) 2015-06-08 2021-08-06 多糖−タンパク質結合体の吸着およびそれから得られた多価のワクチン製剤を改善するための方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN2185MU2015 2015-06-08
IN2185/MUM/2015 2015-06-08
PCT/IB2016/053265 WO2016199003A1 (en) 2015-06-08 2016-06-03 Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021129726A Division JP2021185152A (ja) 2015-06-08 2021-08-06 多糖−タンパク質結合体の吸着およびそれから得られた多価のワクチン製剤を改善するための方法

Publications (3)

Publication Number Publication Date
JP2018516962A JP2018516962A (ja) 2018-06-28
JP2018516962A5 true JP2018516962A5 (enExample) 2019-07-11
JP7258463B2 JP7258463B2 (ja) 2023-04-17

Family

ID=57503115

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017564108A Active JP7258463B2 (ja) 2015-06-08 2016-06-03 多糖-タンパク質結合体の吸着およびそれから得られた多価のワクチン製剤を改善するための方法
JP2021129726A Pending JP2021185152A (ja) 2015-06-08 2021-08-06 多糖−タンパク質結合体の吸着およびそれから得られた多価のワクチン製剤を改善するための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021129726A Pending JP2021185152A (ja) 2015-06-08 2021-08-06 多糖−タンパク質結合体の吸着およびそれから得られた多価のワクチン製剤を改善するための方法

Country Status (17)

Country Link
US (1) US10729780B2 (enExample)
EP (1) EP3302542A4 (enExample)
JP (2) JP7258463B2 (enExample)
KR (2) KR102876828B1 (enExample)
CN (1) CN107847571A (enExample)
AU (2) AU2016276269B2 (enExample)
CA (1) CA2988366C (enExample)
CO (1) CO2017012628A2 (enExample)
EA (1) EA201792470A1 (enExample)
IL (1) IL256118B (enExample)
MX (1) MX2017015985A (enExample)
MY (1) MY187461A (enExample)
PE (1) PE20180460A1 (enExample)
PH (1) PH12017502244A1 (enExample)
SA (1) SA517390495B1 (enExample)
WO (1) WO2016199003A1 (enExample)
ZA (1) ZA201708325B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102143534B1 (ko) 2015-05-04 2020-08-12 화이자 인코포레이티드 B군 스트렙토코쿠스 폴리사카라이드-단백질 접합체, 접합체를 생산하는 방법, 접합체를 포함하는 면역원성 조성물, 및 그의 용도
US10729780B2 (en) * 2015-06-08 2020-08-04 Serum Institute Of India Private Ltd. Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof
CN106822884B (zh) * 2016-12-28 2021-04-30 北京民海生物科技有限公司 一种多价肺炎球菌荚膜多糖结合疫苗的制备方法
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
IL267709B2 (en) 2016-12-30 2025-04-01 Vaxcyte Inc Polypeptide-antigen conjugates with unnatural amino acids
CN110392690B (zh) * 2017-02-24 2024-01-30 默沙东有限责任公司 肺炎球菌缀合物疫苗制剂
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
CA3074706A1 (en) * 2017-09-07 2019-03-14 Merck Sharp & Dohme Corp. Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates
EP3720483B1 (en) 2017-12-06 2025-11-19 Merck Sharp & Dohme LLC Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
CN108524926B (zh) * 2018-06-29 2021-06-29 康希诺生物股份公司 一种多价肺炎球菌结合疫苗的制剂组合及其应用
GB201818517D0 (en) * 2018-11-13 2018-12-26 Univ Liverpool John Moores Nanoparticles and uses thereof
EP3897705A2 (en) 2018-12-19 2021-10-27 Merck Sharp & Dohme Corp. Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
CA3142692A1 (en) * 2019-06-05 2020-12-10 Merck Sharp & Dohme Corp. An immunogenic serotype 35b pneumococcal polysaccharide-protein conjugate and conjugation process for making the same
US12473379B2 (en) 2019-09-06 2025-11-18 Serum Institute Of India Private Limited Method for obtaining purified bacterial polysaccharides
CN113607939B (zh) * 2021-08-05 2024-10-22 艾美探索者生命科学研发有限公司 肺炎球菌多糖结合疫苗各型结合原液吸附率测定方法
CN115006522B (zh) * 2022-06-16 2025-08-22 北京智飞绿竹生物制药有限公司 一种双价痢疾结合物组合疫苗的制备方法
CA3232076A1 (en) * 2023-04-17 2025-04-14 Serum Institute Of India Private Limited Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2059692C (en) 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
DK1587537T3 (da) * 2003-01-30 2012-07-16 Novartis Ag Injicerbare vacciner mod multiple meningococ-serogrupper
AU2004263135B2 (en) * 2003-08-06 2010-11-25 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Polysaccharide-protein conjugate vaccines
EP1871411A4 (en) * 2005-04-18 2010-07-21 Novartis Vaccines & Diagnostic EXPRESSION OF HEPATITIS B VIRUS SURFACE ANTIGEN FOR VACCINE MANUFACTURE
JP5792920B2 (ja) * 2005-12-22 2015-10-14 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
WO2007071786A2 (en) * 2005-12-23 2007-06-28 Glaxosmithkline Biologicals Sa Conjugate vaccines
TW200806315A (en) * 2006-04-26 2008-02-01 Wyeth Corp Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
EA200901578A1 (ru) * 2007-06-26 2010-08-30 Глаксосмитклайн Байолоджикалс С.А. Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae
TW201136603A (en) 2010-02-09 2011-11-01 Merck Sharp & Amp Dohme Corp 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition
US20130273098A1 (en) * 2010-12-10 2013-10-17 Jeffrey T. Blue Novel formulations which mitigate agitation-induced aggregation of immunogenic compositions
US9198977B2 (en) 2012-01-30 2015-12-01 Serum Institute Of India Ltd. Immunogenic composition
KR102057217B1 (ko) 2012-06-20 2020-01-22 에스케이바이오사이언스 주식회사 다가 폐렴구균 다당류-단백질 접합체 조성물
PT2885007T (pt) * 2012-08-16 2018-12-10 Pfizer Processos e composições de glicoconjugação
CN103893751B (zh) * 2014-03-26 2016-04-20 天津康希诺生物技术有限公司 一种肺炎球菌多糖蛋白缀合疫苗及其制备方法
US10729780B2 (en) * 2015-06-08 2020-08-04 Serum Institute Of India Private Ltd. Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof

Similar Documents

Publication Publication Date Title
JP7258463B2 (ja) 多糖-タンパク質結合体の吸着およびそれから得られた多価のワクチン製剤を改善するための方法
CA3066911C (en) Multivalent conjugate vaccines with bivalent or multivalent conjugate polysaccharides that provide improved immunogenicity and avidity
US8753649B2 (en) Polysaccharide-protein conjugate vaccines
CN103623405B (zh) 多糖-蛋白轭合物疫苗
CA2863178C (en) Immunogenic composition
JP2020533438A5 (enExample)
JP2020533442A5 (enExample)
JP2019513821A5 (enExample)
US20230115072A1 (en) Immunogenic Compositions of Polysaccharide-Protein Pegylated Compounds
MX2012010388A (es) Proceso de conjugacion de polisacaridos bacterianos con proteinas portadoras.
KR20190044663A (ko) 네이세리아 메닌기티디스 백신
CA3201450A1 (en) Bacterial protein carriers and conjugation methods
CN108743936B (zh) 一种细菌多糖结合疫苗及其制备方法与应用
NZ738090B2 (en) Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof
RU2023120100A (ru) Пневмококковые полисахариды и их применение в иммуногенных конъюгатах полисахарид-белок-носитель
RU2020112314A (ru) Пневмококковые полисахариды и их применение в иммуногенных конъюгатах полисахарид-белок-носитель
RU2020112308A (ru) Пневмококковые полисахариды и их применение в иммуногенных конъюгатах полисахарид-белок-носитель