PL3570879T3 - Kompozycje immunogenne do zastosowania w szczepionkach przeciw pneumokokom - Google Patents
Kompozycje immunogenne do zastosowania w szczepionkach przeciw pneumokokomInfo
- Publication number
- PL3570879T3 PL3570879T3 PL18701573T PL18701573T PL3570879T3 PL 3570879 T3 PL3570879 T3 PL 3570879T3 PL 18701573 T PL18701573 T PL 18701573T PL 18701573 T PL18701573 T PL 18701573T PL 3570879 T3 PL3570879 T3 PL 3570879T3
- Authority
- PL
- Poland
- Prior art keywords
- immunogenic compositions
- pneumococcal vaccines
- pneumococcal
- vaccines
- immunogenic
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229960001973 pneumococcal vaccines Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762448485P | 2017-01-20 | 2017-01-20 | |
| PCT/IB2018/050084 WO2018134693A1 (en) | 2017-01-20 | 2018-01-05 | Immunogenic compositions for use in pneumococcal vaccines |
| EP18701573.0A EP3570879B1 (en) | 2017-01-20 | 2018-01-05 | Immunogenic compositions for use in pneumococcal vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3570879T3 true PL3570879T3 (pl) | 2022-06-20 |
Family
ID=61028107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18701573T PL3570879T3 (pl) | 2017-01-20 | 2018-01-05 | Kompozycje immunogenne do zastosowania w szczepionkach przeciw pneumokokom |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11413344B2 (pl) |
| EP (1) | EP3570879B1 (pl) |
| JP (1) | JP7120767B2 (pl) |
| KR (1) | KR102459629B1 (pl) |
| CN (1) | CN110198735A (pl) |
| AU (1) | AU2018208844B2 (pl) |
| BR (1) | BR112019014833A2 (pl) |
| DK (1) | DK3570879T3 (pl) |
| ES (1) | ES2911490T3 (pl) |
| HR (1) | HRP20220573T1 (pl) |
| HU (1) | HUE059252T2 (pl) |
| IL (1) | IL268168A (pl) |
| MX (1) | MX392525B (pl) |
| PL (1) | PL3570879T3 (pl) |
| RU (1) | RU2762723C2 (pl) |
| SI (1) | SI3570879T1 (pl) |
| WO (1) | WO2018134693A1 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2710393C2 (ru) * | 2014-01-21 | 2019-12-26 | Пфайзер Инк. | Способ получения иммуногенного конъюгата капсульный полисахарид Streptococcus pneumoniae-белок-носитель |
| TWI756893B (zh) * | 2015-07-21 | 2022-03-01 | 美商輝瑞股份有限公司 | 包含經共軛之莢膜糖抗原的致免疫性組成物、包含該致免疫性組成物之套組及彼等之用途 |
| EP3558363A1 (en) | 2016-12-21 | 2019-10-30 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| MX2019007910A (es) | 2016-12-30 | 2019-12-05 | Sutrovax Inc | Conjugados de polipeptido-antigeno con aminoacidos no naturales. |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| AU2018208844B2 (en) | 2017-01-20 | 2021-02-25 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| KR20190108583A (ko) | 2017-01-31 | 2019-09-24 | 머크 샤프 앤드 돔 코포레이션 | 다당류-단백질 접합체 제조 방법 |
| CA3050120A1 (en) | 2017-02-24 | 2018-08-30 | Merck Sharp & Dohme Corp. | Enhancing immunogenicity of streptococcus pneumoniae polysaccharide-protein conjugates |
| US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
| CN111093649B (zh) | 2017-09-07 | 2023-08-25 | 默沙东有限责任公司 | 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途 |
| CN111065387B (zh) | 2017-09-07 | 2023-08-25 | 默沙东有限责任公司 | 肺炎球菌多糖及其在免疫原性多糖-载体蛋白缀合物中的用途 |
| US11116828B2 (en) | 2017-12-06 | 2021-09-14 | Merck Sharp & Dohme Corp. | Compositions comprising Streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
| US20210252125A1 (en) | 2018-04-30 | 2021-08-19 | Merck Sharp & Dohme Corp. | Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates |
| US11896656B2 (en) | 2018-04-30 | 2024-02-13 | Merck Sharp & Dohme Llc | Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide |
| WO2019212842A1 (en) | 2018-04-30 | 2019-11-07 | Merck Sharp & Dohme Corp. | Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates from lyospheres |
| BR112021011961A8 (pt) | 2018-12-19 | 2023-02-07 | Merck Sharp & Dohme | Composições compreendendo conjugados de polissacarídeo-proteína de streptococcus pneumoniae e métodos de uso dos mesmos |
| CN116322779A (zh) | 2020-09-10 | 2023-06-23 | 联合免疫股份有限公司 | 复合体 |
| WO2022101745A2 (en) | 2020-11-10 | 2022-05-19 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| WO2024241172A2 (en) | 2023-05-19 | 2024-11-28 | Glaxosmithkline Biologicals Sa | Methods for eliciting an immune response to respiratory syncycial virus and streptococcus pneumoniae infection |
Family Cites Families (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4709017A (en) | 1985-06-07 | 1987-11-24 | President And Fellows Of Harvard College | Modified toxic vaccines |
| US4950740A (en) | 1987-03-17 | 1990-08-21 | Cetus Corporation | Recombinant diphtheria vaccines |
| GB8815795D0 (en) | 1988-07-02 | 1988-08-10 | Bkl Extrusions Ltd | Glazing bead |
| NZ230747A (en) | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
| ES2055785T3 (es) | 1989-01-17 | 1994-09-01 | Eniricerche Spa | Peptidos sinteticos y su uso como vehiculos universales para la preparacion de conjugados inmunogenos aptos para el desarrollo de vacunas sinteticas. |
| FI920131A0 (fi) | 1989-07-14 | 1992-01-13 | Praxis Biolog Inc | Cytokin- och hormonbaerare foer konjugatvaccin. |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| DE69113564T2 (de) | 1990-08-13 | 1996-05-30 | American Cyanamid Co | Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff. |
| EP1958646A1 (en) | 1992-02-11 | 2008-08-20 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Dual carrier immunogenic construct |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| EP0643559B1 (en) | 1992-05-06 | 1999-04-14 | The President And Fellows Of Harvard College | Diphtheria toxin receptor-binding region |
| EP0671948B1 (en) | 1992-06-25 | 1997-08-13 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccine composition containing adjuvants |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| ES2231770T3 (es) | 1993-03-05 | 2005-05-16 | Wyeth Holdings Corporation | Nuevos plasmidos para la produccion de proteina crm y toxina difterica. |
| ES2109685T5 (es) | 1993-03-23 | 2005-09-01 | Smithkline Beecham Biologicals S.A. | Composiciones para vacunas que contienen monofosforil-lipido a 3-o-desacilado. |
| NZ274376A (en) | 1993-09-22 | 1997-11-24 | Jackson H M Found Military Med | Activating soluble carbohydrate using cyanylating reagents for the production of immunogenic constructs |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US5917017A (en) | 1994-06-08 | 1999-06-29 | President And Fellows Of Harvard College | Diphtheria toxin vaccines bearing a mutated R domain |
| US6455673B1 (en) | 1994-06-08 | 2002-09-24 | President And Fellows Of Harvard College | Multi-mutant diphtheria toxin vaccines |
| US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| CA2560114A1 (en) | 1994-07-15 | 1996-02-01 | The University Of Iowa Research Foundation | Immunomodulatory oligonucleotides |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| ES2200059T3 (es) | 1995-03-22 | 2004-03-01 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Produccion de construcciones inmunogenicas usando carbohidratos solubles activados mediante reactivos cianilados organicos. |
| GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| AUPO517897A0 (en) | 1997-02-19 | 1997-04-11 | Csl Limited | Chelating immunostimulating complexes |
| EP1039935A4 (en) | 1997-02-28 | 2005-04-27 | Univ Iowa Res Found | USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS |
| US6299881B1 (en) | 1997-03-24 | 2001-10-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts |
| ATE370740T1 (de) | 1997-05-20 | 2007-09-15 | Ottawa Health Research Inst | Verfahren zur herstellung von nukleinsäurekonstrukten |
| GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| DE69838992T2 (de) | 1997-09-05 | 2008-12-24 | Glaxosmithkline Biologicals S.A., Rixensart | Öl-in-Wasser Emulsionen mit Saponinen |
| US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
| CA2323929C (en) | 1998-04-03 | 2004-03-09 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
| WO1999052549A1 (en) | 1998-04-09 | 1999-10-21 | Smithkline Beecham Biologicals S.A. | Adjuvant compositions |
| GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| DK1126876T3 (da) | 1998-10-16 | 2007-07-02 | Glaxosmithkline Biolog Sa | Adjuvanssystemer og vacciner |
| PT1140157E (pt) | 1998-12-21 | 2009-05-06 | Medimmune Inc | Proteínas de streptococcus pneumoniae e fragmentos imunogénicos para vacinas |
| PT2261358E (pt) | 1998-12-23 | 2014-07-30 | Id Biomedical Corp Quebec | Antigénios de streptococcus |
| AUPP807399A0 (en) | 1999-01-08 | 1999-02-04 | Csl Limited | Improved immunogenic lhrh composition and methods relating thereto |
| EP2204186B1 (en) | 1999-02-17 | 2016-04-06 | CSL Limited | Immunogenic complexes and methods relating thereto |
| IL145043A0 (en) | 1999-03-19 | 2002-06-30 | Smithkline Beecham Biolog | Vaccine |
| US6936258B1 (en) | 1999-03-19 | 2005-08-30 | Nabi Biopharmaceuticals | Staphylococcus antigen and vaccine |
| JP2002541808A (ja) | 1999-04-09 | 2002-12-10 | テクラブ, インコーポレイテッド | ポリサッカリド結合体ワクチンのための組換えトキシンaタンパク質キャリア |
| TR200103018T2 (tr) | 1999-04-19 | 2002-02-21 | Beecham Biologicals S.A. Smithkline | İmmünostimülatör oligonükleotid ve saponin içeren katkı bileşikleri. |
| EP1221971A2 (en) | 1999-09-24 | 2002-07-17 | SmithKline Beecham Biologics SA | Use of the combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines |
| CA2383110A1 (en) | 1999-09-24 | 2001-03-29 | Veronique Henderickx | Adjuvant comprising a polyoxyethylene alkyl ether or ester and at least one non-ionic surfactant |
| GB0007432D0 (en) | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Proteins for use as carriers in conjugate vaccines |
| EA006232B1 (ru) | 2000-06-20 | 2005-10-27 | Ай Ди Биомедикал Корпорейшн | Стрептококковые антигены |
| US20030035806A1 (en) | 2001-05-11 | 2003-02-20 | D'ambra Anello J. | Novel meningitis conjugate vaccine |
| CA2492823A1 (en) | 2001-09-14 | 2003-03-27 | Martin F. Bachmann | In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles |
| US7262024B2 (en) | 2001-12-20 | 2007-08-28 | Id Biomedical Corporation | Streptococcus antigens |
| JP4597123B2 (ja) | 2003-03-13 | 2010-12-15 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 細菌性細胞溶解素の精製方法 |
| CA2519511A1 (en) | 2003-03-17 | 2004-09-30 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant and an antigen carrier protein |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| AU2005333126A1 (en) | 2004-07-18 | 2006-12-21 | Csl Limited | Methods and compositions for inducing innate immune responses |
| EP1781325A2 (en) | 2004-07-18 | 2007-05-09 | CSL Limited | Immuno stimulating complex and oligonucleotide formulations for inducing enhanced interferon-gamma responses |
| GB0421083D0 (en) | 2004-09-22 | 2004-10-27 | Glaxosmithkline Biolog Sa | Purification process |
| US7718791B2 (en) | 2005-04-08 | 2010-05-18 | Wyeth Llc | Separation of contaminants from Streptococcus pneumoniae polysaccharide by pH manipulation |
| CN102716480B (zh) | 2005-04-08 | 2023-03-21 | 惠氏有限责任公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物 |
| US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US7955605B2 (en) | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US20070184072A1 (en) | 2005-04-08 | 2007-08-09 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| GB0607088D0 (en) * | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| DK2384765T3 (en) * | 2005-12-22 | 2017-01-09 | Glaxosmithkline Biologicals Sa | Vaccine against Streptococcus pneumoniae. |
| MX2009003730A (es) | 2006-10-10 | 2009-04-22 | Wyeth Corp | Purificacion de polisacaridos de streptococcus pneumoniae tipo 3. |
| SI2436700T1 (sl) | 2007-03-23 | 2018-09-28 | Wyeth Llc | Skrajšan postopek čiščenja za proizvodnjo kapsularnih polisaharidov streptococcusa pneumoniae |
| PL2167121T3 (pl) | 2007-06-26 | 2016-01-29 | Glaxosmithkline Biologicals Sa | Szczepionka zawierająca koniugaty polisacharydu otoczkowego streptococcus pneumoniae |
| NZ595291A (en) | 2009-03-24 | 2013-08-30 | Novartis Ag | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
| WO2010125480A1 (en) | 2009-04-30 | 2010-11-04 | Coley Pharmaceutical Group, Inc. | Pneumococcal vaccine and uses thereof |
| SG10201403702SA (en) | 2009-06-29 | 2014-09-26 | Genocea Biosciences Inc | Vaccines and compositions against streptococcus pneumoniae |
| CN102068690A (zh) * | 2010-12-31 | 2011-05-25 | 北京民海生物科技有限公司 | 多价肺炎球菌荚膜多糖结合疫苗及其制备方法 |
| CA2881420C (en) | 2012-08-16 | 2016-11-15 | Pfizer Inc. | Glycoconjugation processes and compositions |
| FI3363806T3 (fi) | 2012-12-20 | 2023-01-31 | Glykokonjugaatiomenetelmä | |
| CN103495161B (zh) | 2013-10-08 | 2019-06-18 | 江苏康泰生物医学技术有限公司 | 一种多元肺炎球菌荚膜多糖-蛋白质结合物的混合物及其制备方法 |
| US20160324949A1 (en) * | 2014-01-21 | 2016-11-10 | Pfizer Inc. | Streptococcus pneumoniae capsular polysaccharides and conjugates thereof |
| NZ721943A (en) * | 2014-01-21 | 2022-07-01 | Pfizer | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| CN104069504B (zh) | 2014-05-11 | 2019-09-24 | 江苏康泰生物医学技术有限公司 | 一种增强多糖蛋白结合物免疫原性的方法 |
| IL252915B2 (en) | 2015-01-15 | 2024-04-01 | Pfizer | Immunogenic compositions for use in pneumococcal vaccines |
| AU2018208844B2 (en) | 2017-01-20 | 2021-02-25 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
-
2018
- 2018-01-05 AU AU2018208844A patent/AU2018208844B2/en not_active Ceased
- 2018-01-05 PL PL18701573T patent/PL3570879T3/pl unknown
- 2018-01-05 KR KR1020197020691A patent/KR102459629B1/ko active Active
- 2018-01-05 EP EP18701573.0A patent/EP3570879B1/en active Active
- 2018-01-05 RU RU2019122619A patent/RU2762723C2/ru active
- 2018-01-05 HU HUE18701573A patent/HUE059252T2/hu unknown
- 2018-01-05 HR HRP20220573TT patent/HRP20220573T1/hr unknown
- 2018-01-05 BR BR112019014833A patent/BR112019014833A2/pt not_active IP Right Cessation
- 2018-01-05 SI SI201830655T patent/SI3570879T1/sl unknown
- 2018-01-05 WO PCT/IB2018/050084 patent/WO2018134693A1/en not_active Ceased
- 2018-01-05 DK DK18701573.0T patent/DK3570879T3/da active
- 2018-01-05 CN CN201880007697.1A patent/CN110198735A/zh active Pending
- 2018-01-05 MX MX2019008564A patent/MX392525B/es unknown
- 2018-01-05 ES ES18701573T patent/ES2911490T3/es active Active
- 2018-01-05 US US16/478,265 patent/US11413344B2/en active Active
- 2018-01-17 JP JP2018005492A patent/JP7120767B2/ja active Active
-
2019
- 2019-07-18 IL IL268168A patent/IL268168A/en unknown
-
2022
- 2022-07-15 US US17/812,777 patent/US12318438B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US11413344B2 (en) | 2022-08-16 |
| CA3050622A1 (en) | 2018-07-26 |
| RU2019122619A3 (pl) | 2021-02-20 |
| EP3570879B1 (en) | 2022-03-30 |
| AU2018208844B2 (en) | 2021-02-25 |
| JP7120767B2 (ja) | 2022-08-17 |
| BR112019014833A2 (pt) | 2020-04-14 |
| KR102459629B1 (ko) | 2022-10-28 |
| SI3570879T1 (sl) | 2022-06-30 |
| US12318438B2 (en) | 2025-06-03 |
| HUE059252T2 (hu) | 2022-11-28 |
| KR20190097176A (ko) | 2019-08-20 |
| IL268168A (en) | 2019-09-26 |
| ES2911490T3 (es) | 2022-05-19 |
| JP2018115159A (ja) | 2018-07-26 |
| EP3570879A1 (en) | 2019-11-27 |
| RU2762723C2 (ru) | 2021-12-22 |
| MX2019008564A (es) | 2019-09-19 |
| US20190343946A1 (en) | 2019-11-14 |
| MX392525B (es) | 2025-03-12 |
| WO2018134693A1 (en) | 2018-07-26 |
| CN110198735A (zh) | 2019-09-03 |
| US20230190907A1 (en) | 2023-06-22 |
| RU2019122619A (ru) | 2021-02-20 |
| HRP20220573T1 (hr) | 2022-06-10 |
| DK3570879T3 (da) | 2022-04-11 |
| AU2018208844A1 (en) | 2019-07-11 |
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