JP2025128174A5 - - Google Patents
Info
- Publication number
- JP2025128174A5 JP2025128174A5 JP2025087103A JP2025087103A JP2025128174A5 JP 2025128174 A5 JP2025128174 A5 JP 2025128174A5 JP 2025087103 A JP2025087103 A JP 2025087103A JP 2025087103 A JP2025087103 A JP 2025087103A JP 2025128174 A5 JP2025128174 A5 JP 2025128174A5
- Authority
- JP
- Japan
- Prior art keywords
- polysaccharide
- immunogenic composition
- carrier protein
- kda
- conjugate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762555455P | 2017-09-07 | 2017-09-07 | |
| US62/555,455 | 2017-09-07 | ||
| PCT/US2018/049306 WO2019050814A1 (en) | 2017-09-07 | 2018-09-04 | ANTI-PNEUMOCOCCAL POLYSACCHARIDES AND THEIR USE IN IMMUNOGENIC CONJUGATES POLYSACCHARIDE-PROTEIN CARRIER |
| JP2020513530A JP2020533437A (ja) | 2017-09-07 | 2018-09-04 | 肺炎球菌多糖体および免疫原性多糖体−キャリアタンパク質コンジュゲートでのその使用 |
| JP2023096312A JP2023113922A (ja) | 2017-09-07 | 2023-06-12 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023096312A Division JP2023113922A (ja) | 2017-09-07 | 2023-06-12 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025128174A JP2025128174A (ja) | 2025-09-02 |
| JP2025128174A5 true JP2025128174A5 (enExample) | 2025-10-10 |
Family
ID=65635315
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020513530A Pending JP2020533437A (ja) | 2017-09-07 | 2018-09-04 | 肺炎球菌多糖体および免疫原性多糖体−キャリアタンパク質コンジュゲートでのその使用 |
| JP2023096312A Pending JP2023113922A (ja) | 2017-09-07 | 2023-06-12 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
| JP2025087103A Pending JP2025128174A (ja) | 2017-09-07 | 2025-05-26 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020513530A Pending JP2020533437A (ja) | 2017-09-07 | 2018-09-04 | 肺炎球菌多糖体および免疫原性多糖体−キャリアタンパク質コンジュゲートでのその使用 |
| JP2023096312A Pending JP2023113922A (ja) | 2017-09-07 | 2023-06-12 | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (6) | US11491216B2 (enExample) |
| EP (1) | EP3678655A4 (enExample) |
| JP (3) | JP2020533437A (enExample) |
| KR (2) | KR102783492B1 (enExample) |
| CN (2) | CN117736348A (enExample) |
| AU (2) | AU2018328036B2 (enExample) |
| BR (1) | BR112020004396A8 (enExample) |
| CA (1) | CA3074706A1 (enExample) |
| MX (2) | MX2020002559A (enExample) |
| WO (1) | WO2019050814A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3096783T (pt) * | 2014-01-21 | 2021-08-16 | Pfizer | Polissacáridos capsulares de streptococcus pneumoniae e conjugados dos mesmos |
| US11160855B2 (en) * | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| MX2019007910A (es) | 2016-12-30 | 2019-12-05 | Sutrovax Inc | Conjugados de polipeptido-antigeno con aminoacidos no naturales. |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| KR102650073B1 (ko) | 2017-01-31 | 2024-03-20 | 머크 샤프 앤드 돔 엘엘씨 | 스트렙토코커스 뉴모니아 혈청형 19f 유래의 협막 다당류 단백질 접합체의 제조 방법 |
| EP4656208A2 (en) | 2017-01-31 | 2025-12-03 | Merck Sharp & Dohme LLC | Methods for making polysaccharide-protein conjugates |
| US11400162B2 (en) | 2017-02-24 | 2022-08-02 | Merck Sharp & Dohme Llc | Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein |
| US11090374B2 (en) * | 2017-02-24 | 2021-08-17 | Merck Sharp & Dohme Corp. | Enhancing immunogenicity of Streptococcus pneumoniae polysaccharide-protein conjugates |
| US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
| CA3074708A1 (en) * | 2017-09-07 | 2019-03-14 | Merck Sharp & Dohme Corp. | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| US11524076B2 (en) | 2017-09-07 | 2022-12-13 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| CA3074703A1 (en) | 2017-09-07 | 2019-03-14 | Merck Sharp & Dohme Corp. | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| US11491216B2 (en) * | 2017-09-07 | 2022-11-08 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| AU2018328040B2 (en) | 2017-09-07 | 2025-01-16 | Merck Sharp & Dohme Llc | Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein |
| US11389540B2 (en) | 2017-09-07 | 2022-07-19 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| US12257295B2 (en) * | 2017-10-04 | 2025-03-25 | Pogona, LLC | Saccharide-polypeptide conjugate compositions and methods of use thereof |
| KR102686858B1 (ko) | 2017-12-06 | 2024-07-19 | 머크 샤프 앤드 돔 엘엘씨 | 스트렙토코쿠스 뉴모니아에 폴리사카라이드-단백질 접합체를 포함하는 조성물 및 그의 사용 방법 |
| EP3788143B1 (en) | 2018-04-30 | 2023-06-28 | Merck Sharp & Dohme LLC | Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide |
| WO2019212846A1 (en) | 2018-04-30 | 2019-11-07 | Merck Sharp & Dohme Corp. | Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates |
| KR20210005161A (ko) | 2018-04-30 | 2021-01-13 | 머크 샤프 앤드 돔 코포레이션 | 리오스피어로부터 스트렙토코쿠스 뉴모니아에 피막 폴리사카라이드 담체 단백질 접합체를 제조하는 방법 |
| MY206212A (en) | 2018-09-23 | 2024-12-04 | Biological E Ltd | Purified capsular polysaccharides of streptococcus pneumoniae |
| WO2020131763A2 (en) | 2018-12-19 | 2020-06-25 | Merck Sharp & Dohme Corp. | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
| JP2021132644A (ja) * | 2020-02-21 | 2021-09-13 | ファイザー・インク | 糖の精製 |
| WO2022169787A1 (en) * | 2021-02-04 | 2022-08-11 | Merck Sharp & Dohme Llc | Lipid nanoparticle adjuvant composition for pneumococcal conjugate vaccines |
| PE20251701A1 (es) | 2022-11-22 | 2025-07-02 | Pfizer | Composiciones inmunogenas que comprenden antigenos de sacarido capsular conjugados y sus usos |
| KR20250113501A (ko) | 2022-12-01 | 2025-07-25 | 화이자 인코포레이티드 | 폐렴구균 접합체 백신 제형 |
| WO2025057078A1 (en) | 2023-09-14 | 2025-03-20 | Pfizer Inc. | Adjuvanted immunogenic compositions comprising conjugated pneumococcal capsular saccharide antigens and uses thereof |
| WO2025219908A2 (en) | 2024-04-19 | 2025-10-23 | Pfizer Inc. | Media and fermentation methods for polysaccharide production in bacterial cell culture |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2059693C (en) | 1991-01-28 | 2003-08-19 | Peter J. Kniskern | Polysaccharide antigens from streptococcus pneumoniae |
| CA2059692C (en) | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| EP2425856A1 (en) * | 2005-04-08 | 2012-03-07 | Wyeth LLC | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US7955605B2 (en) * | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| DK1976974T3 (da) * | 2005-12-28 | 2014-09-15 | Uab Research Foundation | Pneumokok-serotyper. |
| GB0703369D0 (en) * | 2007-02-21 | 2007-03-28 | Health Prot Agency | Compositions Comprising Capsular Polysaccharides and Their Use as Vaccines |
| EP2323684B1 (en) * | 2008-07-31 | 2014-05-21 | The Government of The United States of America as represented by the Secretary of The Department of Health and Human Services, Centers for Disease | Use of a pneumococcal p4 peptide for enhancing opsonophagocytosis in response to a pathogen |
| TW201136603A (en) | 2010-02-09 | 2011-11-01 | Merck Sharp & Amp Dohme Corp | 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition |
| AU2011262346B2 (en) | 2010-06-04 | 2014-12-11 | Wyeth Llc | Streptococcus pneumoniae vaccine formulations |
| RU2013131795A (ru) * | 2010-12-10 | 2015-01-20 | Мерк Шарп Энд Домэ Корп. | Новые композиции, которые уменьшают вызываемую встряхиванием агрегацию иммуногенных композиций |
| CN104519910B (zh) * | 2012-03-07 | 2017-05-03 | 诺华股份有限公司 | 肺炎链球菌抗原的含佐剂制剂 |
| EP3421051B1 (en) | 2012-08-16 | 2020-05-13 | Pfizer Inc | Glycoconjugation processes and compositions |
| CN103623401A (zh) * | 2012-08-23 | 2014-03-12 | 北京科兴中维生物技术有限公司 | 多价肺炎球菌荚膜多糖-蛋白质共轭组合物及其制备方法 |
| EP3096785B1 (en) * | 2014-01-21 | 2020-09-09 | Pfizer Inc | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| EP3443983B1 (en) * | 2014-02-14 | 2022-07-20 | Pfizer Inc. | Immunogenic glycoprotein conjugates |
| MX378792B (es) * | 2014-08-08 | 2025-03-10 | Glaxosmithkline Biologicals Sa | Células hospederas modificadas y oligosacáridos híbridos para su uso en producción de bioconjugados. |
| CA2988366C (en) * | 2015-06-08 | 2021-12-07 | Serum Institute Of India Private Ltd. | Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof. |
| IL303998A (en) * | 2015-07-21 | 2023-08-01 | Pfizer | Immunogenic preparations containing conjugated capsular sugar antigens, kits containing them and their uses |
| EP3436061A4 (en) | 2016-03-31 | 2019-12-04 | Liffey Biotech Limited | Saccharide-polypeptide-conjugate compositions and methods of use thereof |
| EP3292131B1 (en) * | 2016-04-14 | 2019-05-01 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Improved preparation of vaccines against streptococcus pneumoniae type 3 |
| GB201610599D0 (en) * | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
| DE112016006945T5 (de) * | 2016-06-30 | 2019-03-28 | Ford Global Technologies, Llc | Systeme, verfahren und vorrichtungen für einen rahmenfesten pedaltrittfrequenzsensor |
| KR102650073B1 (ko) | 2017-01-31 | 2024-03-20 | 머크 샤프 앤드 돔 엘엘씨 | 스트렙토코커스 뉴모니아 혈청형 19f 유래의 협막 다당류 단백질 접합체의 제조 방법 |
| EP4656208A2 (en) | 2017-01-31 | 2025-12-03 | Merck Sharp & Dohme LLC | Methods for making polysaccharide-protein conjugates |
| CN110392690B (zh) | 2017-02-24 | 2024-01-30 | 默沙东有限责任公司 | 肺炎球菌缀合物疫苗制剂 |
| US11400162B2 (en) * | 2017-02-24 | 2022-08-02 | Merck Sharp & Dohme Llc | Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein |
| EP3585427A4 (en) | 2017-02-24 | 2020-12-30 | Merck Sharp & Dohme Corp. | METHODS FOR IMPROVING THE FILTRABILITY OF POLYSACCHARIDE CONJUGATE WITH PROTEIN REACTIONS |
| US11090374B2 (en) | 2017-02-24 | 2021-08-17 | Merck Sharp & Dohme Corp. | Enhancing immunogenicity of Streptococcus pneumoniae polysaccharide-protein conjugates |
| US11219680B2 (en) * | 2017-02-24 | 2022-01-11 | Merck Sharp & Dohme Corp. | Polysaccharide-protein conjugates utilizing diphtheria toxin fragment B as a carrier |
| US11739356B2 (en) * | 2017-05-05 | 2023-08-29 | Serum Institute Of India Private Limited | Method for removal of impurities from bacterial capsular polysaccharide based preparations |
| GB201711637D0 (en) * | 2017-07-19 | 2017-08-30 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| GB201711635D0 (en) * | 2017-07-19 | 2017-08-30 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| WO2019036313A1 (en) | 2017-08-16 | 2019-02-21 | Merck Sharp & Dohme Corp. | CONJUGATED PNEUMOCOCCAL VACCINE FORMULATIONS |
| AU2018328040B2 (en) | 2017-09-07 | 2025-01-16 | Merck Sharp & Dohme Llc | Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein |
| US11389540B2 (en) * | 2017-09-07 | 2022-07-19 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| US11491216B2 (en) * | 2017-09-07 | 2022-11-08 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| CA3074708A1 (en) | 2017-09-07 | 2019-03-14 | Merck Sharp & Dohme Corp. | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| CA3074703A1 (en) * | 2017-09-07 | 2019-03-14 | Merck Sharp & Dohme Corp. | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| US11524076B2 (en) * | 2017-09-07 | 2022-12-13 | Merck Sharp & Dohme Llc | Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates |
| KR20200077538A (ko) | 2017-10-25 | 2020-06-30 | 머크 샤프 앤드 돔 코포레이션 | 아주반트 첨가된 백신 |
| KR102686858B1 (ko) * | 2017-12-06 | 2024-07-19 | 머크 샤프 앤드 돔 엘엘씨 | 스트렙토코쿠스 뉴모니아에 폴리사카라이드-단백질 접합체를 포함하는 조성물 및 그의 사용 방법 |
| KR20210005161A (ko) * | 2018-04-30 | 2021-01-13 | 머크 샤프 앤드 돔 코포레이션 | 리오스피어로부터 스트렙토코쿠스 뉴모니아에 피막 폴리사카라이드 담체 단백질 접합체를 제조하는 방법 |
| WO2020131763A2 (en) * | 2018-12-19 | 2020-06-25 | Merck Sharp & Dohme Corp. | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
| CN114364397B (zh) * | 2019-07-18 | 2024-03-29 | 赛特瑞恩股份有限公司 | 含多价肺炎链球菌多糖-蛋白偶联物的免疫原性组合物、药物组合物及其用途 |
| WO2022035816A1 (en) * | 2020-08-10 | 2022-02-17 | Inventprise, Llc | Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f |
-
2018
- 2018-09-04 US US16/645,048 patent/US11491216B2/en active Active
- 2018-09-04 BR BR112020004396A patent/BR112020004396A8/pt unknown
- 2018-09-04 EP EP18854598.2A patent/EP3678655A4/en active Pending
- 2018-09-04 WO PCT/US2018/049306 patent/WO2019050814A1/en not_active Ceased
- 2018-09-04 KR KR1020207009613A patent/KR102783492B1/ko active Active
- 2018-09-04 JP JP2020513530A patent/JP2020533437A/ja active Pending
- 2018-09-04 CN CN202311711412.1A patent/CN117736348A/zh active Pending
- 2018-09-04 AU AU2018328036A patent/AU2018328036B2/en active Active
- 2018-09-04 CN CN201880058250.7A patent/CN111065388A/zh active Pending
- 2018-09-04 CA CA3074706A patent/CA3074706A1/en active Pending
- 2018-09-04 MX MX2020002559A patent/MX2020002559A/es unknown
- 2018-09-04 KR KR1020257008384A patent/KR20250046326A/ko active Pending
-
2020
- 2020-03-05 MX MX2022014850A patent/MX2022014850A/es unknown
-
2022
- 2022-09-22 US US17/934,379 patent/US20230075760A1/en active Pending
- 2022-09-22 US US17/934,396 patent/US20230107713A1/en active Pending
- 2022-09-27 US US17/935,864 patent/US20230041441A1/en active Pending
- 2022-09-27 US US17/935,871 patent/US20230029424A1/en active Pending
- 2022-09-27 US US17/935,856 patent/US20230094548A1/en active Pending
-
2023
- 2023-06-12 JP JP2023096312A patent/JP2023113922A/ja active Pending
-
2024
- 2024-03-06 AU AU2024201479A patent/AU2024201479A1/en active Pending
-
2025
- 2025-05-26 JP JP2025087103A patent/JP2025128174A/ja active Pending
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