JP2012524099A5 - - Google Patents
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- Publication number
- JP2012524099A5 JP2012524099A5 JP2012506176A JP2012506176A JP2012524099A5 JP 2012524099 A5 JP2012524099 A5 JP 2012524099A5 JP 2012506176 A JP2012506176 A JP 2012506176A JP 2012506176 A JP2012506176 A JP 2012506176A JP 2012524099 A5 JP2012524099 A5 JP 2012524099A5
- Authority
- JP
- Japan
- Prior art keywords
- psaa
- vaccine
- capsular polysaccharide
- pharmaceutical composition
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229960005486 vaccine Drugs 0.000 claims description 10
- 125000000539 amino acid group Chemical group 0.000 claims description 7
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 claims description 3
- 150000004676 glycans Chemical class 0.000 claims 8
- 229920001282 polysaccharide Polymers 0.000 claims 8
- 239000005017 polysaccharide Substances 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 230000028993 immune response Effects 0.000 claims 4
- 241000947238 Neisseria meningitidis serogroup C Species 0.000 claims 2
- 239000002671 adjuvant Substances 0.000 claims 2
- -1 carrier Substances 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 241000588650 Neisseria meningitidis Species 0.000 claims 1
- 150000001413 amino acids Chemical group 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 230000002163 immunogen Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 108010040473 pneumococcal surface protein A Proteins 0.000 description 2
- 102000018697 Membrane Proteins Human genes 0.000 description 1
- 108010052285 Membrane Proteins Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 101710183389 Pneumolysin Proteins 0.000 description 1
- 101000832034 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) Inactive diphosphatase DCS2 Proteins 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 229960000856 protein c Drugs 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/425,232 US8003112B2 (en) | 2009-04-16 | 2009-04-16 | Meningococcal and pneumococcal conjugate vaccine and method of using same |
| US12/425,232 | 2009-04-16 | ||
| PCT/US2010/031083 WO2010120921A1 (en) | 2009-04-16 | 2010-04-14 | Meningococcal and pneumococcal conjugate vaccine and method of using same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012524099A JP2012524099A (ja) | 2012-10-11 |
| JP2012524099A5 true JP2012524099A5 (enExample) | 2014-11-13 |
| JP5744842B2 JP5744842B2 (ja) | 2015-07-08 |
Family
ID=42981141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012506176A Active JP5744842B2 (ja) | 2009-04-16 | 2010-04-14 | 髄膜炎菌と肺炎球菌との結合型ワクチン及びそれを使用する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8003112B2 (enExample) |
| EP (1) | EP2419130A4 (enExample) |
| JP (1) | JP5744842B2 (enExample) |
| CA (1) | CA2758921C (enExample) |
| WO (1) | WO2010120921A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8003112B2 (en) * | 2009-04-16 | 2011-08-23 | Howard University | Meningococcal and pneumococcal conjugate vaccine and method of using same |
| KR20150020164A (ko) * | 2012-05-15 | 2015-02-25 | 수브하시 브이. 카프레 | 보강제 제형 및 방법 |
| RU2510281C2 (ru) | 2012-06-22 | 2014-03-27 | Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") | ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА |
| US10402608B2 (en) * | 2014-09-12 | 2019-09-03 | Ent. Services Development Corporation Lp | Radio frequency identification card monitor |
| US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| PH12019500672B1 (en) * | 2016-09-30 | 2024-02-23 | Biological E Ltd | Multivalent pneumococcal vaccine compositions comprising polysachharide-protein conjugates |
| EP3562838A2 (en) | 2016-12-28 | 2019-11-06 | Henriques Normark, Birgitta | Microparticles from streptococcus pneumoniae as vaccine antigens |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| CN121548426A (zh) * | 2023-05-22 | 2026-02-17 | Gpn疫苗有限公司 | 修饰的链球菌免疫原和其用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356170A (en) * | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| NZ239643A (en) * | 1990-09-17 | 1996-05-28 | North American Vaccine Inc | Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group. |
| US5849301A (en) * | 1993-09-22 | 1998-12-15 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Producing immunogenic constructs using soluable carbohydrates activated via organic cyanylating reagents |
| US20020054884A1 (en) * | 1995-06-23 | 2002-05-09 | Smithkline Beecham Biologicals, Sa | Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate |
| PT2332581E (pt) * | 2001-01-23 | 2015-10-16 | Sanofi Pasteur Inc | Vacina meningocócica tri- ou tetravalente de conjugados de polissacárido e crm-197 |
| US20030035806A1 (en) * | 2001-05-11 | 2003-02-20 | D'ambra Anello J. | Novel meningitis conjugate vaccine |
| BRPI0410423A (pt) * | 2003-05-07 | 2006-06-06 | Sanofi Pasteur Inc | processo de imunogenicidade melhorada para vacinação meningocócica |
| US8048432B2 (en) * | 2003-08-06 | 2011-11-01 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Polysaccharide-protein conjugate vaccines |
| CA2844154C (en) | 2003-08-06 | 2016-12-20 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Polysaccharide-protein conjugate vaccines |
| US20070065462A1 (en) * | 2005-09-21 | 2007-03-22 | Ryall Robert P | Multivalent meningococcal derivatized polysaccharide-protein conjugates and vaccine |
| US8003112B2 (en) * | 2009-04-16 | 2011-08-23 | Howard University | Meningococcal and pneumococcal conjugate vaccine and method of using same |
-
2009
- 2009-04-16 US US12/425,232 patent/US8003112B2/en active Active
-
2010
- 2010-04-14 JP JP2012506176A patent/JP5744842B2/ja active Active
- 2010-04-14 EP EP10765117.6A patent/EP2419130A4/en not_active Withdrawn
- 2010-04-14 WO PCT/US2010/031083 patent/WO2010120921A1/en not_active Ceased
- 2010-04-14 CA CA2758921A patent/CA2758921C/en active Active
-
2011
- 2011-07-14 US US13/183,303 patent/US20120009213A1/en not_active Abandoned
-
2014
- 2014-11-20 US US14/549,052 patent/US20150182613A1/en not_active Abandoned
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