HK1199705A1 - Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof -3- - Google Patents

Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof -3-

Info

Publication number
HK1199705A1
HK1199705A1 HK15100097.5A HK15100097A HK1199705A1 HK 1199705 A1 HK1199705 A1 HK 1199705A1 HK 15100097 A HK15100097 A HK 15100097A HK 1199705 A1 HK1199705 A1 HK 1199705A1
Authority
HK
Hong Kong
Prior art keywords
kynurenine
methods
pharmaceutical compositions
monooxygenase inhibitors
monooxygenase
Prior art date
Application number
HK15100097.5A
Other languages
English (en)
Chinese (zh)
Inventor
Stephen Martin Courtney
Michael Prime
William Mitchell
Christopher John Brown
Paula C De Aguiar Pena
Peter Johnson
Celia Dominguez
Leticia M Toledo-Sherman
Ignacio Munoz
Original Assignee
Chdi Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chdi Foundation Inc filed Critical Chdi Foundation Inc
Publication of HK1199705A1 publication Critical patent/HK1199705A1/xx

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    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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HK15100097.5A 2011-08-30 2015-01-06 Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof -3- HK1199705A1 (en)

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