FR2635263A1 - Composition of polyunsaturated fatty acids based on eicosapentaenoic and docosahexaenoic acids - Google Patents

Composition of polyunsaturated fatty acids based on eicosapentaenoic and docosahexaenoic acids Download PDF

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Publication number
FR2635263A1
FR2635263A1 FR8910780A FR8910780A FR2635263A1 FR 2635263 A1 FR2635263 A1 FR 2635263A1 FR 8910780 A FR8910780 A FR 8910780A FR 8910780 A FR8910780 A FR 8910780A FR 2635263 A1 FR2635263 A1 FR 2635263A1
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FR
France
Prior art keywords
fatty acids
acids
weight
omega
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8910780A
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English (en)
French (fr)
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FR2635263B1 (cg-RX-API-DMAC7.html
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Norsk Hydro ASA
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Norsk Hydro ASA
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10641979&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2635263(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Norsk Hydro ASA filed Critical Norsk Hydro ASA
Publication of FR2635263A1 publication Critical patent/FR2635263A1/fr
Application granted granted Critical
Publication of FR2635263B1 publication Critical patent/FR2635263B1/fr
Granted legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
FR8910780A 1988-08-11 1989-08-10 Composition of polyunsaturated fatty acids based on eicosapentaenoic and docosahexaenoic acids Granted FR2635263A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888819110A GB8819110D0 (en) 1988-08-11 1988-08-11 Antihypertensive drug & method for production

Publications (2)

Publication Number Publication Date
FR2635263A1 true FR2635263A1 (en) 1990-02-16
FR2635263B1 FR2635263B1 (cg-RX-API-DMAC7.html) 1992-02-14

Family

ID=10641979

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8910780A Granted FR2635263A1 (en) 1988-08-11 1989-08-10 Composition of polyunsaturated fatty acids based on eicosapentaenoic and docosahexaenoic acids

Country Status (24)

Country Link
US (3) US5502077A (cg-RX-API-DMAC7.html)
JP (1) JP2810916B2 (cg-RX-API-DMAC7.html)
KR (1) KR0126286B1 (cg-RX-API-DMAC7.html)
AT (1) AT398779B (cg-RX-API-DMAC7.html)
AU (1) AU616784B2 (cg-RX-API-DMAC7.html)
BE (1) BE1002547A5 (cg-RX-API-DMAC7.html)
CA (1) CA1337548C (cg-RX-API-DMAC7.html)
CH (1) CH680789A5 (cg-RX-API-DMAC7.html)
DE (1) DE3926658C2 (cg-RX-API-DMAC7.html)
DK (1) DK173371B1 (cg-RX-API-DMAC7.html)
ES (1) ES2018384A6 (cg-RX-API-DMAC7.html)
FI (1) FI893805L (cg-RX-API-DMAC7.html)
FR (1) FR2635263A1 (cg-RX-API-DMAC7.html)
GB (2) GB8819110D0 (cg-RX-API-DMAC7.html)
GR (1) GR1000567B (cg-RX-API-DMAC7.html)
HK (1) HK84196A (cg-RX-API-DMAC7.html)
IE (1) IE64524B1 (cg-RX-API-DMAC7.html)
IL (1) IL91275A (cg-RX-API-DMAC7.html)
IT (1) IT1235879B (cg-RX-API-DMAC7.html)
LU (1) LU87570A1 (cg-RX-API-DMAC7.html)
NL (1) NL193459C (cg-RX-API-DMAC7.html)
NZ (1) NZ230022A (cg-RX-API-DMAC7.html)
SE (1) SE504742C2 (cg-RX-API-DMAC7.html)
ZA (1) ZA895512B (cg-RX-API-DMAC7.html)

Cited By (31)

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WO2010028067A1 (en) * 2008-09-02 2010-03-11 Amarin Corporation Plc Pharmaceutical composition comprising eicosapentaenoic acid and nicotinic acid and methods of using same
ITMI20100961A1 (it) * 2010-05-27 2011-11-28 Erredue Spa Miscele ricche in esteri di acidi grassi omega-3, loro composizioni e loro processo di preparazione
US8293728B2 (en) 2009-02-10 2012-10-23 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US8298554B2 (en) 2009-04-29 2012-10-30 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
US8410086B2 (en) 2009-06-15 2013-04-02 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides
US8563608B2 (en) 2009-04-29 2013-10-22 Amarin Pharmaceuticals Ireland Limited Methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
US9603826B2 (en) 2012-06-29 2017-03-28 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US9827219B2 (en) 2012-01-06 2017-11-28 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering levels of high-sensitivity C-reactive protein (HS-CRP) in a subject
US10166209B2 (en) 2013-02-06 2019-01-01 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US10172818B2 (en) 2014-06-16 2019-01-08 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
US10206898B2 (en) 2013-03-14 2019-02-19 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US10292959B2 (en) 2013-10-10 2019-05-21 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
US10493058B2 (en) 2009-09-23 2019-12-03 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
US10537544B2 (en) 2011-11-07 2020-01-21 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
US10668042B2 (en) 2018-09-24 2020-06-02 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of cardiovascular events in a subject
US10888539B2 (en) 2013-09-04 2021-01-12 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US10966951B2 (en) 2017-05-19 2021-04-06 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject having reduced kidney function
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
US11141399B2 (en) 2012-12-31 2021-10-12 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US11179362B2 (en) 2012-11-06 2021-11-23 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US11547710B2 (en) 2013-03-15 2023-01-10 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US11712428B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US11986452B2 (en) 2021-04-21 2024-05-21 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of heart failure
US12427134B2 (en) 2019-11-12 2025-09-30 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of cardiovascular events in a subject with atrial fibrillation and/or atrial flutter

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NZ230022A (en) 1990-10-26
US5656667A (en) 1997-08-12
DK392089D0 (da) 1989-08-10
CH680789A5 (cg-RX-API-DMAC7.html) 1992-11-13
DE3926658C2 (de) 1998-10-15
FI893805A0 (fi) 1989-08-11
GR1000567B (el) 1992-08-26
KR0126286B1 (ko) 1997-12-26
GB8819110D0 (en) 1988-09-14
DK392089A (da) 1990-02-12
IE64524B1 (en) 1995-08-09
KR900002771A (ko) 1990-03-23
FR2635263B1 (cg-RX-API-DMAC7.html) 1992-02-14
NL193459B (nl) 1999-07-01
GB2221843A (en) 1990-02-21
IT8921521A0 (it) 1989-08-11
CA1337548C (en) 1995-11-14
AU616784B2 (en) 1991-11-07
BE1002547A5 (fr) 1991-03-19
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ZA895512B (en) 1990-07-25
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ATA191889A (de) 1994-06-15
GR890100507A (en) 1990-08-22
FI893805A7 (fi) 1990-02-12
US5698594A (en) 1997-12-16
DE3926658A1 (de) 1990-02-15
US5502077A (en) 1996-03-26
LU87570A1 (fr) 1990-01-08
SE8902701D0 (sv) 1989-08-09
AT398779B (de) 1995-01-25
GB8917711D0 (en) 1989-09-20
SE504742C2 (sv) 1997-04-14
ES2018384A6 (es) 1991-04-01
HK84196A (en) 1996-05-24
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NL193459C (nl) 1999-11-02
IT1235879B (it) 1992-11-23
GB2221843B (en) 1992-12-02
JP2810916B2 (ja) 1998-10-15
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IL91275A0 (en) 1990-03-19
FI893805L (fi) 1990-02-12

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