FR2482967A1 - Nouveaux derives de l'imidazo-rifamycine, leur procede de preparation et leur application en therapeutique - Google Patents

Nouveaux derives de l'imidazo-rifamycine, leur procede de preparation et leur application en therapeutique Download PDF

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Publication number
FR2482967A1
FR2482967A1 FR8110058A FR8110058A FR2482967A1 FR 2482967 A1 FR2482967 A1 FR 2482967A1 FR 8110058 A FR8110058 A FR 8110058A FR 8110058 A FR8110058 A FR 8110058A FR 2482967 A1 FR2482967 A1 FR 2482967A1
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France
Prior art keywords
existent
formula
rifamycin
hydrogen atom
compounds
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Granted
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FR8110058A
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English (en)
French (fr)
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FR2482967B1 (cg-RX-API-DMAC10.html
Inventor
Egidio Marchi
Lauretta Montecchi
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Alfa Farmaceutici SpA
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Alfa Farmaceutici SpA
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Publication of FR2482967A1 publication Critical patent/FR2482967A1/fr
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Granted legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR8110058A 1980-05-22 1981-05-20 Nouveaux derives de l'imidazo-rifamycine, leur procede de preparation et leur application en therapeutique Granted FR2482967A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03429/80A IT1154655B (it) 1980-05-22 1980-05-22 Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Publications (2)

Publication Number Publication Date
FR2482967A1 true FR2482967A1 (fr) 1981-11-27
FR2482967B1 FR2482967B1 (cg-RX-API-DMAC10.html) 1985-03-29

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ID=11107198

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FR8110058A Granted FR2482967A1 (fr) 1980-05-22 1981-05-20 Nouveaux derives de l'imidazo-rifamycine, leur procede de preparation et leur application en therapeutique

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US (1) US4341785A (cg-RX-API-DMAC10.html)
JP (1) JPS5711987A (cg-RX-API-DMAC10.html)
AR (1) AR226212A1 (cg-RX-API-DMAC10.html)
AT (1) AT373599B (cg-RX-API-DMAC10.html)
AU (1) AU537093B2 (cg-RX-API-DMAC10.html)
BE (1) BE888895A (cg-RX-API-DMAC10.html)
CA (1) CA1142518A (cg-RX-API-DMAC10.html)
CH (1) CH648037A5 (cg-RX-API-DMAC10.html)
DE (1) DE3120460A1 (cg-RX-API-DMAC10.html)
DK (1) DK157876C (cg-RX-API-DMAC10.html)
EG (1) EG14891A (cg-RX-API-DMAC10.html)
ES (1) ES8203388A1 (cg-RX-API-DMAC10.html)
FI (1) FI69467C (cg-RX-API-DMAC10.html)
FR (1) FR2482967A1 (cg-RX-API-DMAC10.html)
GB (1) GB2079270B (cg-RX-API-DMAC10.html)
GR (1) GR75640B (cg-RX-API-DMAC10.html)
IE (1) IE51204B1 (cg-RX-API-DMAC10.html)
IT (1) IT1154655B (cg-RX-API-DMAC10.html)
LU (1) LU83376A1 (cg-RX-API-DMAC10.html)
NL (1) NL187022C (cg-RX-API-DMAC10.html)
NO (1) NO155622C (cg-RX-API-DMAC10.html)
PH (2) PH17207A (cg-RX-API-DMAC10.html)
PT (1) PT73064B (cg-RX-API-DMAC10.html)
SE (1) SE453089B (cg-RX-API-DMAC10.html)
ZA (1) ZA813430B (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0161534A3 (en) * 1984-05-15 1987-03-04 Alfa Farmaceutici S.P.A. New process for the synthesis of pyrido-imidazo-refamycins

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AU2002364162A1 (en) * 2001-12-13 2003-06-30 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
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US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US7923553B2 (en) * 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
US7906542B2 (en) * 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
US7902206B2 (en) * 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US7256187B2 (en) * 2004-03-10 2007-08-14 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime derivatives effective against drug-resistant microbes
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ITBO20050123A1 (it) * 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
BRPI0614758A2 (pt) 2005-08-11 2011-04-12 Targanta Therapeutics Inc rifamicinas fosfonadas e usos destas para a prevenção e tratamento de infecções na articulação e osso
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SI2054066T1 (sl) 2006-08-02 2015-08-31 Salix Pharmaceuticals, Inc. Postopki za zdravljenje radiacijskega enteritisa
ITMI20061692A1 (it) 2006-09-05 2008-03-06 Alfa Wassermann Spa Uso di polioli per ottenere forme polimorfe stabili di rifaximina
CA2663776C (en) * 2006-09-22 2016-01-26 Cipla Limited Rifaximin in an amorphous form
US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
US20080161337A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Chronic Prostatitis
ITMI20071241A1 (it) * 2007-06-20 2008-12-21 Solmag S P A Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta
AU2008273699A1 (en) 2007-07-06 2009-01-15 Lupin Limited Pharmaceutical compositions of rifaximin
PT2011486E (pt) 2007-07-06 2012-08-24 Lupin Ltd Composições farmacêuticas de rifaximina
US7709634B2 (en) * 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
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US8486956B2 (en) 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
AU2009219240B2 (en) 2008-02-26 2014-10-16 Salix Pharmaceuticals, Ltd. Methods for treating bowel diseases
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EP2324041A4 (en) 2008-08-13 2012-06-13 Targanta Therapeutics Corp PHOSPHONIZED RIFAMYCINS AND ITS APPLICATION FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS
WO2010035751A1 (ja) 2008-09-26 2010-04-01 あすか製薬株式会社 機能性消化管障害の予防及び／又は治療剤
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KR20190000931A (ko) 2009-10-27 2019-01-03 루핀 리미티드 리팍시민의 고형 분산물
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ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
RU2496475C2 (ru) 2011-10-26 2013-10-27 Александр Васильевич Иващенко Фармацевтическая композиция и набор для лечения бактериальных инфекций
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2426690A2 (fr) * 1978-06-09 1979-12-21 Archifar Lab Chim Farm Composes de rifamycine

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
DE273377C (cg-RX-API-DMAC10.html) *
AT273377B (de) * 1967-03-01 1969-08-11 Lepetit Spa Verfahren zur Herstellung von neuen Rifamycinen
AT344898B (de) * 1975-06-13 1978-08-10 Archifar Ind Chim Trentino Verfahren zur herstellung neuer rifamycin-verbindungen
DK345977A (da) * 1976-09-30 1978-03-31 Archifar Ind Chim Trentino G rifamycinforbindelser og fremgangsmaade til deres fremstillin
CH629212A5 (it) * 1976-10-18 1982-04-15 Erba Farmitalia Procedimento per la preparazione di composti di rifamicina.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2426690A2 (fr) * 1978-06-09 1979-12-21 Archifar Lab Chim Farm Composes de rifamycine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0161534A3 (en) * 1984-05-15 1987-03-04 Alfa Farmaceutici S.P.A. New process for the synthesis of pyrido-imidazo-refamycins

Also Published As

Publication number Publication date
AU7065581A (en) 1981-11-26
NL187022B (nl) 1990-12-03
PH18704A (en) 1985-09-05
ES502906A0 (es) 1982-04-01
GB2079270B (en) 1984-01-18
IT1154655B (it) 1987-01-21
ES8203388A1 (es) 1982-04-01
DK224781A (da) 1981-11-23
GB2079270A (en) 1982-01-20
GR75640B (cg-RX-API-DMAC10.html) 1984-08-02
CH648037A5 (de) 1985-02-28
DK157876B (da) 1990-02-26
NO811731L (no) 1981-11-23
DE3120460A1 (de) 1982-03-11
FI811565L (fi) 1981-11-23
IT8003429A0 (it) 1980-05-22
LU83376A1 (fr) 1981-09-11
DE3120460C2 (cg-RX-API-DMAC10.html) 1990-12-13
FI69467C (fi) 1986-02-10
NL187022C (nl) 1991-05-01
JPS5711987A (en) 1982-01-21
AU537093B2 (en) 1984-06-07
NO155622C (no) 1987-04-29
FR2482967B1 (cg-RX-API-DMAC10.html) 1985-03-29
AR226212A1 (es) 1982-06-15
NL8102290A (nl) 1981-12-16
JPS6123192B2 (cg-RX-API-DMAC10.html) 1986-06-04
IE51204B1 (en) 1986-10-29
PT73064B (en) 1982-07-05
SE8103216L (sv) 1981-11-23
SE453089B (sv) 1988-01-11
IE811139L (en) 1981-11-22
PH17207A (en) 1984-06-19
PT73064A (en) 1981-06-01
BE888895A (fr) 1981-09-16
NO155622B (no) 1987-01-19
ATA222781A (de) 1983-06-15
FI69467B (fi) 1985-10-31
CA1142518A (en) 1983-03-08
EG14891A (en) 1985-12-31
AT373599B (de) 1984-02-10
DK157876C (da) 1990-07-30
ZA813430B (en) 1982-06-30
US4341785A (en) 1982-07-27

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