IT201700091912A1 - Nuove pirido-imidazo rifamicine - Google Patents

Nuove pirido-imidazo rifamicine

Info

Publication number
IT201700091912A1
IT201700091912A1 IT102017000091912A IT201700091912A IT201700091912A1 IT 201700091912 A1 IT201700091912 A1 IT 201700091912A1 IT 102017000091912 A IT102017000091912 A IT 102017000091912A IT 201700091912 A IT201700091912 A IT 201700091912A IT 201700091912 A1 IT201700091912 A1 IT 201700091912A1
Authority
IT
Italy
Prior art keywords
rifamicine
pirido
imidazo
new
new pirido
Prior art date
Application number
IT102017000091912A
Other languages
English (en)
Inventor
Egidio Marchi
Sacchetti Alessandro Lapini
Claudia Ori
Lisa Preti
Original Assignee
Biofer Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biofer Spa filed Critical Biofer Spa
Priority to IT102017000091912A priority Critical patent/IT201700091912A1/it
Priority to HUE18755539A priority patent/HUE054832T2/hu
Priority to EP18755539.6A priority patent/EP3645539B1/en
Priority to MX2019015681A priority patent/MX2019015681A/es
Priority to ES18755539T priority patent/ES2868180T3/es
Priority to PL18755539T priority patent/PL3645539T3/pl
Priority to PCT/IB2018/054645 priority patent/WO2019003076A1/en
Priority to RU2020102511A priority patent/RU2020102511A/ru
Priority to DK18755539.6T priority patent/DK3645539T3/da
Priority to CN201880040449.7A priority patent/CN110770244A/zh
Publication of IT201700091912A1 publication Critical patent/IT201700091912A1/it
Priority to US16/718,634 priority patent/US11028086B2/en
Priority to US17/314,413 priority patent/US20210363143A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
IT102017000091912A 2017-06-26 2017-08-08 Nuove pirido-imidazo rifamicine IT201700091912A1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT102017000091912A IT201700091912A1 (it) 2017-08-08 2017-08-08 Nuove pirido-imidazo rifamicine
PL18755539T PL3645539T3 (pl) 2017-06-26 2018-06-25 Pochodne pirydoimidazoryfamycyny jako środek przeciwbakteryjny
EP18755539.6A EP3645539B1 (en) 2017-06-26 2018-06-25 Pyrido-imidazo rifamycin derivatives as antibacterial agent
MX2019015681A MX2019015681A (es) 2017-06-26 2018-06-25 Derivados de pirido-imidazo rifamicina como agente antibacteriano.
ES18755539T ES2868180T3 (es) 2017-06-26 2018-06-25 Derivados de pirido-imidazo rifamicina como agentes antibacterianos
HUE18755539A HUE054832T2 (hu) 2017-06-26 2018-06-25 Pirido-imidazo rifamicinszármazékok baktériumellenes szerként
PCT/IB2018/054645 WO2019003076A1 (en) 2017-06-26 2018-06-25 PYRIDO-IMIDAZO-RIFAMYCIN DERIVATIVES AS ANTIBACTERIAL AGENT
RU2020102511A RU2020102511A (ru) 2017-06-26 2018-06-25 Соединения пиридо-имидазо рифамицина в качестве антибактериального средства
DK18755539.6T DK3645539T3 (da) 2017-06-26 2018-06-25 Pyrido-imidazo-rifamycin-derivater som antibakterielt middel
CN201880040449.7A CN110770244A (zh) 2017-06-26 2018-06-25 吡啶并咪唑利福霉素衍生物的抗菌剂
US16/718,634 US11028086B2 (en) 2017-06-26 2019-12-18 Pyrido-imidazo rifamycins
US17/314,413 US20210363143A1 (en) 2017-06-26 2021-05-07 Pyrido-imidazo rifamycins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000091912A IT201700091912A1 (it) 2017-08-08 2017-08-08 Nuove pirido-imidazo rifamicine

Publications (1)

Publication Number Publication Date
IT201700091912A1 true IT201700091912A1 (it) 2019-02-08

Family

ID=61006005

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000091912A IT201700091912A1 (it) 2017-06-26 2017-08-08 Nuove pirido-imidazo rifamicine

Country Status (1)

Country Link
IT (1) IT201700091912A1 (it)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341785A (en) * 1980-05-22 1982-07-27 Alfa Farmaceutici S.P.A. Imidazo-rifamycin derivatives with antibacterial utility
WO2006094662A1 (en) * 2005-03-03 2006-09-14 Alfa Wassermann S.P.A. New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341785A (en) * 1980-05-22 1982-07-27 Alfa Farmaceutici S.P.A. Imidazo-rifamycin derivatives with antibacterial utility
WO2006094662A1 (en) * 2005-03-03 2006-09-14 Alfa Wassermann S.P.A. New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MARCHI E ET AL: "4-deoxypyrido[1',2':1,2]imidazo[5,4-c]rifamycin SV derivatives. A new series of semisynthetic rifamycins with high antibacterial activity and low gastroenteric absorption", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 28, no. 7, 1 January 1985 (1985-01-01), pages 960 - 963, XP002554520, ISSN: 0022-2623, [retrieved on 19850701], DOI: 10.1021/JM00145A020 *

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