|
DE59712555D1
(de)
*
|
1996-06-05 |
2006-04-06 |
Roche Diagnostics Gmbh |
Exendin-analoga, verfahren zu deren herstellung und diese enthaltende arzneimittel
|
|
PT966297E
(pt)
*
|
1996-08-08 |
2009-03-18 |
Amylin Pharmaceuticals Inc |
Regulação da motilidade gastrintestinal
|
|
ES2237790T3
(es)
*
|
1996-11-12 |
2005-08-01 |
Novo Nordisk A/S |
Uso de peptidos glp-1.
|
|
JP4798814B2
(ja)
|
1997-01-07 |
2011-10-19 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
食物摂取低減用のエキセンジンおよびそのアゴニストの使用
|
|
US20040022807A1
(en)
*
|
1998-06-05 |
2004-02-05 |
Duft Bradford J |
Methods for treating obesity
|
|
US7910548B2
(en)
*
|
1997-06-06 |
2011-03-22 |
Amylin Pharmaceuticals, Inc. |
Methods for treating obesity
|
|
EP1938831A1
(en)
*
|
1997-08-08 |
2008-07-02 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
ES2293688T5
(es)
*
|
1997-08-08 |
2011-05-04 |
Amylin Pharmaceuticals, Inc. |
Nuevos compuestos análogos de la exendina.
|
|
US7157555B1
(en)
|
1997-08-08 |
2007-01-02 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
AU2006225176B2
(en)
*
|
1997-11-14 |
2009-01-08 |
Amylin Pharmaceuticals, Llc |
Novel exendin agonist compounds
|
|
EP1938830A1
(en)
*
|
1997-11-14 |
2008-07-02 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
BR9814189A
(pt)
*
|
1997-11-14 |
2000-10-03 |
Amylin Pharmaceuticals Inc |
"compostos agonistas da exendina"
|
|
EP1941900A1
(en)
*
|
1997-11-14 |
2008-07-09 |
Amylin Pharmaceuticals, Inc. |
Novel exendin agonist compounds
|
|
US7220721B1
(en)
|
1997-11-14 |
2007-05-22 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist peptides
|
|
US7223725B1
(en)
|
1997-11-14 |
2007-05-29 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
|
BR9815670A
(pt)
*
|
1997-11-14 |
2000-10-17 |
Amylin Pharmaceuticals Inc |
Compostos agonistas de exendina
|
|
AU2003200129B2
(en)
*
|
1997-11-14 |
2006-06-22 |
Amylin Pharmaceuticals, Llc |
Novel Exendin Agonist Compounds
|
|
US6998387B1
(en)
|
1998-03-19 |
2006-02-14 |
Amylin Pharmaceuticals, Inc. |
Human appetite control by glucagon-like peptide receptor binding compounds
|
|
US6284725B1
(en)
*
|
1998-10-08 |
2001-09-04 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 to improve the function of ischemic and reperfused tissue
|
|
US7259136B2
(en)
|
1999-04-30 |
2007-08-21 |
Amylin Pharmaceuticals, Inc. |
Compositions and methods for treating peripheral vascular disease
|
|
US6429197B1
(en)
|
1998-10-08 |
2002-08-06 |
Bionebraska, Inc. |
Metabolic intervention with GLP-1 or its biologically active analogues to improve the function of the ischemic and reperfused brain
|
|
US7399489B2
(en)
|
1999-01-14 |
2008-07-15 |
Amylin Pharmaceuticals, Inc. |
Exendin analog formulations
|
|
US20030087820A1
(en)
*
|
1999-01-14 |
2003-05-08 |
Young Andrew A. |
Novel exendin agonist formulations and methods of administration thereof
|
|
DK1143989T3
(da)
|
1999-01-14 |
2007-04-16 |
Amylin Pharmaceuticals Inc |
Exendiner til glucagonundertrykkelse
|
|
PT1140145E
(pt)
|
1999-01-14 |
2005-11-30 |
Amylin Pharmaceuticals Inc |
Formulacoes novas de agonistas de exendina e metodos para a sua administracao
|
|
US20050272652A1
(en)
|
1999-03-29 |
2005-12-08 |
Gault Victor A |
Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
|
|
JP2002544127A
(ja)
|
1999-04-30 |
2002-12-24 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
修飾されたエキセンジンおよびエキセンジン・アゴニスト
|
|
US6924264B1
(en)
|
1999-04-30 |
2005-08-02 |
Amylin Pharmaceuticals, Inc. |
Modified exendins and exendin agonists
|
|
US20090175821A1
(en)
*
|
1999-05-17 |
2009-07-09 |
Bridon Dominique P |
Modified therapeutic peptides with extended half-lives in vivo
|
|
US6514500B1
(en)
|
1999-10-15 |
2003-02-04 |
Conjuchem, Inc. |
Long lasting synthetic glucagon like peptide {GLP-!}
|
|
US6506724B1
(en)
*
|
1999-06-01 |
2003-01-14 |
Amylin Pharmaceuticals, Inc. |
Use of exendins and agonists thereof for the treatment of gestational diabetes mellitus
|
|
US6528486B1
(en)
|
1999-07-12 |
2003-03-04 |
Zealand Pharma A/S |
Peptide agonists of GLP-1 activity
|
|
EP1076066A1
(en)
*
|
1999-07-12 |
2001-02-14 |
Zealand Pharmaceuticals A/S |
Peptides for lowering blood glucose levels
|
|
ES2227115T5
(es)
*
|
2000-01-10 |
2014-10-30 |
Amylin Pharmaceuticals, Inc. |
Utilización de exendinas y sus agonistas para el tratamiento de la hipertrigliceridemia
|
|
WO2001066135A1
(en)
*
|
2000-03-08 |
2001-09-13 |
Novo Nordisk A/S |
Lowering serum lipids
|
|
US8273713B2
(en)
|
2000-12-14 |
2012-09-25 |
Amylin Pharmaceuticals, Llc |
Methods of treating obesity using PYY[3-36]
|
|
US20090281032A1
(en)
*
|
2001-03-01 |
2009-11-12 |
Peter Raymond Flatt |
Modified CCK peptides
|
|
ATE408414T1
(de)
|
2001-07-31 |
2008-10-15 |
Us Gov Health & Human Serv |
Glp 1 exendin 4 peptidanaloga und deren verwendungen
|
|
GB0121709D0
(en)
*
|
2001-09-07 |
2001-10-31 |
Imp College Innovations Ltd |
Food inhibition agent
|
|
ATE419863T1
(de)
*
|
2001-09-24 |
2009-01-15 |
Imp Innovations Ltd |
Pyy3-36 zur zur reduzierung oder vorbeugung von fettleibigkeit
|
|
AU2002351752A1
(en)
*
|
2001-12-29 |
2003-07-30 |
Novo Nordisk A/S |
Combined use of a glp-1 compound and another drug for treating dyslipidemia
|
|
WO2003057244A2
(en)
*
|
2002-01-08 |
2003-07-17 |
Amylin Pharmaceuticals, Inc. |
Use of amylin agonists to modulate triglycerides
|
|
CA2472882A1
(en)
*
|
2002-01-10 |
2003-07-17 |
Imperial College Innovations Ltd |
Use of pyy and glp-1, or an agonist thereof, for the modification of feeding behaviour
|
|
US8058233B2
(en)
*
|
2002-01-10 |
2011-11-15 |
Oregon Health And Science University |
Modification of feeding behavior using PYY and GLP-1
|
|
US7105489B2
(en)
*
|
2002-01-22 |
2006-09-12 |
Amylin Pharmaceuticals, Inc. |
Methods and compositions for treating polycystic ovary syndrome
|
|
EP1525219B1
(en)
|
2002-07-04 |
2009-05-27 |
Zealand Pharma A/S |
Glp-1 and methods for treating diabetes
|
|
KR20050083713A
(ko)
|
2002-10-02 |
2005-08-26 |
질랜드 파마 에이/에스 |
안정화된 엑센딘-4 화합물
|
|
WO2004035754A2
(en)
*
|
2002-10-17 |
2004-04-29 |
Alkermes Controlled Therapeutics, Inc. Ii |
Microencapsulation and sustained release of biologically active polypeptides
|
|
JP2006506386A
(ja)
*
|
2002-10-22 |
2006-02-23 |
ワラタ ファーマシューティカルズ, インコーポレイテッド |
糖尿病の処置
|
|
WO2004050115A2
(en)
*
|
2002-12-03 |
2004-06-17 |
Novo Nordisk A/S |
Combination treatment using exendin-4 and thiazolidinediones
|
|
JP2006520747A
(ja)
*
|
2002-12-11 |
2006-09-14 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
多嚢胞性卵巣症候群を治療するための方法および組成物
|
|
US7790681B2
(en)
|
2002-12-17 |
2010-09-07 |
Amylin Pharmaceuticals, Inc. |
Treatment of cardiac arrhythmias with GLP-1 receptor ligands
|
|
US20040209803A1
(en)
*
|
2002-12-19 |
2004-10-21 |
Alain Baron |
Compositions for the treatment and prevention of nephropathy
|
|
US7731947B2
(en)
|
2003-11-17 |
2010-06-08 |
Intarcia Therapeutics, Inc. |
Composition and dosage form comprising an interferon particle formulation and suspending vehicle
|
|
GB0300571D0
(en)
*
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
WO2005000222A2
(en)
*
|
2003-05-30 |
2005-01-06 |
Amylin Pharmaceuticals, Inc. |
Novel methods and compositions for enhanced transmucosal delivery of peptides and proteins
|
|
EP1663289A2
(en)
*
|
2003-08-29 |
2006-06-07 |
Amylin Pharmaceuticals, Inc. |
Methods for treating or ameliorating ghrelin-associated diseases and disorders
|
|
US8263084B2
(en)
*
|
2003-11-13 |
2012-09-11 |
Hanmi Science Co., Ltd |
Pharmaceutical composition for treating obesity-related disease comprising insulinotropic peptide conjugate
|
|
KR101135244B1
(ko)
|
2007-11-29 |
2012-04-24 |
한미사이언스 주식회사 |
인슐린 분비 펩타이드 결합체를 포함하는 비만 관련질환 치료용 조성물
|
|
ATE525083T1
(de)
*
|
2003-11-13 |
2011-10-15 |
Novo Nordisk As |
Pharmazeutische zusammensetzung umfassend eine insulinotrope glp-1(7-37) analoge, asp(b28)- insulin, und eine oberflächenaktive verbindung
|
|
US20060287221A1
(en)
|
2003-11-13 |
2006-12-21 |
Novo Nordisk A/S |
Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia
|
|
DK3300721T4
(da)
|
2003-11-20 |
2025-03-03 |
Novo Nordisk As |
Propylenglycol-holdige peptidformuleringer hvilke er optimale til fremstilling og til anvendelse i injektionsindretninger
|
|
ATE498404T1
(de)
*
|
2003-12-09 |
2011-03-15 |
Novo Nordisk As |
Regulierung der nahrungspräferenz mit glp-1- agonisten
|
|
CN102174115B
(zh)
*
|
2004-02-11 |
2014-05-14 |
安米林药品有限责任公司 |
具有可选择特性的杂合多肽
|
|
NZ571824A
(en)
|
2004-02-11 |
2010-04-30 |
Amylin Pharmaceuticals Inc |
Amylin family peptides and methods for making and using them
|
|
US8076288B2
(en)
|
2004-02-11 |
2011-12-13 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides having glucose lowering activity
|
|
SI2100904T1
(sl)
|
2004-04-23 |
2010-10-29 |
Conjuchem Botechnologies Inc |
Trdna faza za uporabo v postopku čiščenja albumin konjugatov
|
|
US20090069226A1
(en)
*
|
2004-05-28 |
2009-03-12 |
Amylin Pharmaceuticals, Inc. |
Transmucosal delivery of peptides and proteins
|
|
WO2005120492A1
(en)
*
|
2004-06-11 |
2005-12-22 |
Novo Nordisk A/S |
Counteracting drug-induced obesity using glp-1 agonists
|
|
AU2005305036B2
(en)
*
|
2004-11-01 |
2011-03-10 |
Amylin Pharmaceuticals, Llc |
Treatment of obesity and related disorders
|
|
US8394765B2
(en)
*
|
2004-11-01 |
2013-03-12 |
Amylin Pharmaceuticals Llc |
Methods of treating obesity with two different anti-obesity agents
|
|
BRPI0518241A
(pt)
*
|
2004-11-01 |
2008-04-22 |
Amylin Pharmaceuticals Inc |
métodos para tratar obesidade e doenças e distúrbios relacionados à obesidade
|
|
US7393827B2
(en)
*
|
2004-12-30 |
2008-07-01 |
Diakine Therapeutics, Inc. |
Pharmaceutical compositions and methods for restoring β-cell mass and function
|
|
WO2006083761A2
(en)
|
2005-02-03 |
2006-08-10 |
Alza Corporation |
Solvent/polymer solutions as suspension vehicles
|
|
US11246913B2
(en)
|
2005-02-03 |
2022-02-15 |
Intarcia Therapeutics, Inc. |
Suspension formulation comprising an insulinotropic peptide
|
|
US8404637B2
(en)
|
2005-02-11 |
2013-03-26 |
Amylin Pharmaceuticals, Llc |
GIP analog and hybrid polypeptides with selectable properties
|
|
US8263545B2
(en)
|
2005-02-11 |
2012-09-11 |
Amylin Pharmaceuticals, Inc. |
GIP analog and hybrid polypeptides with selectable properties
|
|
US7759312B2
(en)
*
|
2005-03-11 |
2010-07-20 |
Endo Pharmaceuticals Solutions Inc. |
Delivery of dry formulations of octreotide
|
|
JP4584331B2
(ja)
*
|
2005-03-11 |
2010-11-17 |
インデバス ファーマシューティカルズ、インク. |
オクトレオチドの放出制御製剤
|
|
AU2006230602B2
(en)
|
2005-03-31 |
2010-07-15 |
Amylin Pharmaceuticals, Llc |
Amylin and amylin agonists for treating psychiatric diseases and disorders
|
|
GB0511986D0
(en)
*
|
2005-06-13 |
2005-07-20 |
Imp College Innovations Ltd |
Novel compounds and their effects on feeding behaviour
|
|
EP1922336B1
(en)
*
|
2005-08-11 |
2012-11-21 |
Amylin Pharmaceuticals, LLC |
Hybrid polypeptides with selectable properties
|
|
US8389472B2
(en)
|
2005-08-19 |
2013-03-05 |
Amylin Pharmaceuticals, Llc |
Exendin-4 to treat nonalcoholic steatohepatitis and nonalcoholic fatty liver disease
|
|
SG184730A1
(en)
*
|
2005-08-19 |
2012-10-30 |
Amylin Pharmaceuticals Inc |
Methods for treating diabetes and reducing body weight
|
|
US20080255084A1
(en)
|
2005-10-21 |
2008-10-16 |
Randy Lee Webb |
Combination of Organic Compounds
|
|
WO2007055743A2
(en)
*
|
2005-11-01 |
2007-05-18 |
Amylin Pharmaceuticals, Inc. |
Treatment of obesity and related disorders
|
|
EP1954313A1
(en)
*
|
2005-11-01 |
2008-08-13 |
Amylin Pharmaceuticals, Inc. |
Treatment of obesity and related disorders
|
|
WO2007053946A1
(en)
*
|
2005-11-09 |
2007-05-18 |
Conjuchem Biotechnologies Inc. |
Method of treating diabetes and/or obesity with reduced nausea side effects using an insulinotropic peptide conjugated to albumin
|
|
WO2007064124A1
(en)
*
|
2005-11-29 |
2007-06-07 |
Kolon Industries, Inc |
A braid-reinforced composite hollow fiber membrane
|
|
AU2006329215A1
(en)
*
|
2005-12-22 |
2007-06-28 |
Conjuchem Biotechnologies Inc. |
Process for the production of preformed conjugates of albumin and a therapeutic agent
|
|
CA2652907A1
(en)
|
2006-05-26 |
2007-12-06 |
Amylin Pharmaceuticals, Inc. |
Compositions and methods for treatment of diabetes
|
|
NZ572003A
(en)
|
2006-05-30 |
2010-07-30 |
Intarcia Therapeutics Inc |
Two-piece, internal-channel osmotic delivery system flow modulator with spiral fluid channel
|
|
CA2658654A1
(en)
*
|
2006-07-24 |
2008-01-31 |
Biorexis Pharmaceutical Corporation |
Exendin fusion proteins
|
|
EP2066337A2
(en)
*
|
2006-08-04 |
2009-06-10 |
Amylin Pharmaceuticals, Inc. |
Use of exendins, exendin agonists and glp-1 receptor agonists for altering the concentration of fibrinogen
|
|
US20090209469A1
(en)
*
|
2006-08-04 |
2009-08-20 |
Dennis Kim |
Use of Exendins and GLP-1 Receptor Agonists for Altering Lipoprotein Particle Size and Subclass Composition
|
|
EP2359808B1
(en)
|
2006-08-09 |
2013-05-22 |
Intarcia Therapeutics, Inc |
Osmotic delivery systems and piston assemblies
|
|
US8497240B2
(en)
|
2006-08-17 |
2013-07-30 |
Amylin Pharmaceuticals, Llc |
DPP-IV resistant GIP hybrid polypeptides with selectable properties
|
|
JP2010501010A
(ja)
*
|
2006-08-17 |
2010-01-14 |
ウェルスタット セラピューティクス コーポレイション |
代謝障害のための併用処置
|
|
US20090318353A1
(en)
|
2006-08-25 |
2009-12-24 |
Novo Nordisk A/S |
Acylated Exendin-4 Compounds
|
|
KR100872304B1
(ko)
*
|
2006-11-28 |
2008-12-05 |
주식회사 코오롱 |
편물로 보강된 복합 중공사막
|
|
TWI428346B
(zh)
*
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
RU2413528C2
(ru)
|
2007-01-18 |
2011-03-10 |
Открытое Акционерное Общество "Валента Фармацевтика" |
Лекарственный препарат для лечения сахарного диабета на основе экзенатида и даларгина, применение и способ лечения
|
|
ES2402172T3
(es)
|
2007-04-23 |
2013-04-29 |
Intarcia Therapeutics, Inc |
Formulación en suspensión de péptidos insulinotrópicos y usos de los mismos
|
|
JP2009019027A
(ja)
*
|
2007-07-16 |
2009-01-29 |
Hanmi Pharmaceutical Co Ltd |
アミノ末端のアミノ酸が変異したインスリン分泌ペプチド誘導体
|
|
US20100323955A1
(en)
*
|
2007-11-14 |
2010-12-23 |
Amylin Pharmaceuticals, Inc. |
Methods for treating obesity and obesity related diseases and disorders
|
|
WO2009075859A2
(en)
*
|
2007-12-11 |
2009-06-18 |
Conjuchem Biotechnologies Inc. |
Formulation of insulinotropic peptide conjugates
|
|
EP2240155B1
(en)
|
2008-02-13 |
2012-06-06 |
Intarcia Therapeutics, Inc |
Devices, formulations, and methods for delivery of multiple beneficial agents
|
|
WO2009109927A2
(en)
*
|
2008-03-05 |
2009-09-11 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Glp-1 receptor agonists and related active pharmaceutical ingredients for treatment of cancer
|
|
EP2303313B1
(en)
|
2008-05-21 |
2015-10-28 |
Amylin Pharmaceuticals, LLC |
Exendins to lower cholestrol and triglycerides
|
|
KR20110025974A
(ko)
*
|
2008-06-25 |
2011-03-14 |
엔도 파마슈티컬즈, 솔루션스 아이엔씨. |
이형제를 함유하는 옥트레오티드 이식물
|
|
WO2009158412A2
(en)
|
2008-06-25 |
2009-12-30 |
Endo Pharmaceuticals Solutions Inc. |
Sustained delivery of exenatide and other polypeptides
|
|
CA2731236A1
(en)
*
|
2008-07-21 |
2010-01-28 |
Transpharma Medical Ltd. |
Transdermal system for extended delivery of incretins and incretin mimetic peptides
|
|
SG10201703039SA
(en)
|
2008-09-04 |
2017-05-30 |
Amylin Pharmaceuticals Llc |
Sustained release formulations using non-aqueous carriers
|
|
DE102009038210A1
(de)
|
2009-08-20 |
2011-03-03 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
DE102008053048A1
(de)
|
2008-10-24 |
2010-04-29 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
SI2349324T1
(en)
|
2008-10-17 |
2018-01-31 |
Sanofi-Aventis Deutschland Gmbh |
The combination of insulin and agonist GLP-1
|
|
DE102008051834A1
(de)
|
2008-10-17 |
2010-04-22 |
Sanofi-Aventis Deutschland Gmbh |
Kombination von einem Insulin und einem GLP-1-Agonisten
|
|
WO2010096394A2
(en)
*
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
|
CN101870728A
(zh)
|
2009-04-23 |
2010-10-27 |
派格生物医药(苏州)有限公司 |
新型Exendin变体及其缀合物
|
|
WO2010138671A1
(en)
|
2009-05-28 |
2010-12-02 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonist compounds for sleep enhancement
|
|
KR20150006083A
(ko)
|
2009-09-28 |
2015-01-15 |
인타르시아 세라퓨틱스 인코포레이티드 |
실질 항정상태 약물 전달의 신속 확립 및/또는 종결
|
|
WO2011056713A2
(en)
*
|
2009-11-03 |
2011-05-12 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonist compounds for obstructive sleep apnea
|
|
NZ599848A
(en)
|
2009-11-13 |
2013-08-30 |
Sanofi Aventis Deutschland |
Pharmaceutical composition comprising a glp-1 agonist, an insulin, and methionine
|
|
DE102010011919A1
(de)
|
2010-03-18 |
2011-09-22 |
Sanofi-Aventis Deutschland Gmbh |
Pharmazeutische Zusammensetzung umfassend einen GLP-1-Agonisten und Methionin
|
|
ES2965209T3
(es)
|
2009-11-13 |
2024-04-11 |
Sanofi Aventis Deutschland |
Composición farmacéutica que comprende desPro36exendina-4(1-39)-Lys6-NH2 y metionina
|
|
US9445992B2
(en)
|
2009-11-25 |
2016-09-20 |
Arisgen Sa |
Mucosal delivery compositions comprising a peptide complexed with a crown compound and/or a counter ion
|
|
CN102100912B
(zh)
*
|
2009-12-16 |
2015-04-22 |
上海蓝心医药科技有限公司 |
一种给药组合物及其制备和使用方法
|
|
US9168288B2
(en)
|
2010-04-09 |
2015-10-27 |
Mount Sinai Hospital |
Methods for treating disorders of the gastrointestinal tract using a GLP-1 agonist
|
|
NZ603169A
(en)
|
2010-04-27 |
2015-02-27 |
Zealand Pharma As |
Peptide conjugates of glp-1 receptor agonists and gastrin and their use
|
|
WO2012027331A1
(en)
|
2010-08-27 |
2012-03-01 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
|
JP6199186B2
(ja)
|
2010-08-30 |
2017-09-20 |
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
2型糖尿病の治療用の医薬の製造のためのave0010の使用
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
CN103370083B
(zh)
|
2010-09-28 |
2016-11-16 |
艾米琳制药有限责任公司 |
具有增强的作用持续时间的工程化多肽
|
|
WO2012088157A2
(en)
|
2010-12-22 |
2012-06-28 |
Amylin Pharmaceuticals, Inc. |
Glp-1 receptor agonists for islet cell transplantation
|
|
EP2663647A4
(en)
|
2011-01-14 |
2015-08-19 |
Redwood Bioscience Inc |
POLYPEPTIDE IMMUNOGLOBULINS WITH ALDEHYDIC MARKING AND THEIR USE METHOD
|
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
|
CN107090016A
(zh)
|
2011-03-01 |
2017-08-25 |
辛纳吉制药公司 |
制备鸟苷酸环化酶c激动剂的方法
|
|
US9821032B2
(en)
|
2011-05-13 |
2017-11-21 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
|
|
EP2714069A4
(en)
|
2011-05-25 |
2015-06-24 |
Amylin Pharmaceuticals Llc |
LONG-TERM CONJUGATES WITH TWO HORMONES
|
|
ES2634716T3
(es)
|
2011-05-31 |
2017-09-28 |
Celgene International Ii Sàrl |
Nuevos estabilizantes y moduladores del receptor GLP-1
|
|
JP6396211B2
(ja)
|
2011-07-04 |
2018-09-26 |
インペリアル・イノベイションズ・リミテッド |
新規化合物及び摂食行動に対するそれらの効果
|
|
WO2013009545A1
(en)
|
2011-07-08 |
2013-01-17 |
Amylin Pharmaceuticals, Inc. |
Engineered polypeptides having enhanced duration of action with reduced immunogenicity
|
|
CN108079281A
(zh)
|
2011-08-29 |
2018-05-29 |
赛诺菲-安万特德国有限公司 |
用于2型糖尿病患者中的血糖控制的药物组合
|
|
AR087744A1
(es)
|
2011-09-01 |
2014-04-16 |
Sanofi Aventis Deutschland |
Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
|
|
EP2763690B1
(en)
|
2011-10-04 |
2015-11-25 |
Sanofi-Aventis Deutschland GmbH |
Lixisenatide for use in the treatment of stenosis or/and obstruction in the pancreatic duct system
|
|
US20130096059A1
(en)
|
2011-10-04 |
2013-04-18 |
Jens Stechl |
Glp-1 agonist for use in the treatment of stenosis or/and obstruction in the biliary tract
|
|
AU2012331053A1
(en)
|
2011-11-03 |
2014-05-29 |
Zealand Pharma A/S |
GLP-1 receptor agonist peptide gastrin conjugates
|
|
CA2857197C
(en)
|
2011-12-12 |
2019-11-26 |
Receptos, Inc. |
Novel glp-1 receptor modulators
|
|
SG11201407860PA
(en)
|
2012-06-14 |
2014-12-30 |
Sanofi Sa |
Exendin-4 peptide analogues
|
|
PL2875043T3
(pl)
|
2012-07-23 |
2017-06-30 |
Zealand Pharma A/S |
Analogi glukagonu
|
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
|
UA116217C2
(uk)
|
2012-10-09 |
2018-02-26 |
Санофі |
Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
|
|
WO2014096149A1
(en)
|
2012-12-21 |
2014-06-26 |
Sanofi |
Exendin-4 Derivatives
|
|
KR101581497B1
(ko)
|
2013-01-24 |
2015-12-30 |
강원대학교산학협력단 |
인삼열매 추출물을 포함하는 파킨슨병과 알츠하이머병의 예방 또는 치료용 조성물
|
|
TWI780236B
(zh)
|
2013-02-04 |
2022-10-11 |
法商賽諾菲公司 |
胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
|
|
ES2644016T3
(es)
|
2013-03-01 |
2017-11-27 |
Fundació Hospital Universitari Vall D' Hebron - Institut De Recerca |
Péptidos para su uso en el tratamiento tópico de enfermedades neurodegenerativas retinianas, en particular en estadios tempranos de retinopatía diabética y otras enfermedades retinianas en las que la neurodegeneración desempeña un papel esencial
|
|
PL3004138T3
(pl)
|
2013-06-05 |
2024-07-29 |
Bausch Health Ireland Limited |
Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
|
|
MX370666B
(es)
|
2013-06-11 |
2019-12-19 |
Celgene Int Ii Sarl |
Novedosos moduladores del receptor de péptido tipo glucagón 1 (glp-1).
|
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
|
WO2015055801A1
(en)
|
2013-10-17 |
2015-04-23 |
Zealand Pharma A/S |
Acylated glucagon analogues
|
|
KR20160083884A
(ko)
|
2013-11-01 |
2016-07-12 |
스페리움 바이오메드 에스.엘. |
치료제 및 미용제의 경피 전달을 위한 봉입체
|
|
KR102310389B1
(ko)
|
2013-11-06 |
2021-10-13 |
질랜드 파마 에이/에스 |
Gip-glp-1 이원 효능제 화합물 및 방법
|
|
EA035688B1
(ru)
|
2013-11-06 |
2020-07-27 |
Зилэнд Фарма А/С |
Соединения, которые представляют собой тройные агонисты глюкагона, glp-1 и gip
|
|
TW201609799A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
雙重glp-1/gip受體促效劑
|
|
WO2015086728A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
|
|
TW201609797A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
雙重glp-1/升糖素受體促效劑
|
|
EP3080152A1
(en)
|
2013-12-13 |
2016-10-19 |
Sanofi |
Non-acylated exendin-4 peptide analogues
|
|
AU2015205621A1
(en)
|
2014-01-09 |
2016-07-14 |
Sanofi |
Stabilized glycerol free pharmaceutical formulations of insulin analogues and/or insulin derivatives
|
|
KR20160101195A
(ko)
|
2014-01-09 |
2016-08-24 |
사노피 |
인슐린 아스파트의 안정화된 약제학적 제형
|
|
MX2016008979A
(es)
|
2014-01-09 |
2016-10-04 |
Sanofi Sa |
Formulaciones farmaceuticas estabilizadas de analogos de insulina y/o derivados de insulina.
|
|
TW201625669A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
|
|
TW201625668A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
|
|
TW201625670A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自exendin-4之雙重glp-1/升糖素受體促效劑
|
|
US9932381B2
(en)
|
2014-06-18 |
2018-04-03 |
Sanofi |
Exendin-4 derivatives as selective glucagon receptor agonists
|
|
EP3172199B1
(en)
|
2014-07-25 |
2020-07-01 |
Celgene International II Sarl |
Pyrimidine derivatives as glp-1 receptor modulators
|
|
RU2573933C1
(ru)
|
2014-08-21 |
2016-01-27 |
Дафот Энтерпрайсис Лимитед |
Пептид для лечения сахарного диабета 2-го типа и его осложнений
|
|
CA2959208C
(en)
|
2014-08-29 |
2023-09-19 |
Tes Pharma S.R.L. |
Pyrimidine derivatives and their use as inhibitors of alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase
|
|
US9889085B1
(en)
|
2014-09-30 |
2018-02-13 |
Intarcia Therapeutics, Inc. |
Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
|
|
KR102620911B1
(ko)
|
2014-10-29 |
2024-01-05 |
질랜드 파마 에이/에스 |
Gip 효능제 화합물 및 방법
|
|
KR102497644B1
(ko)
|
2014-12-10 |
2023-02-08 |
리셉토스 엘엘씨 |
Glp-1 수용체 조절제
|
|
JP6970615B2
(ja)
|
2014-12-12 |
2021-11-24 |
サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
インスリングラルギン/リキシセナチド固定比処方
|
|
BR112017019170A2
(pt)
|
2015-03-09 |
2018-07-10 |
Intekrin Therapeutics, Inc. |
métodos para o tratamento de doença do fígado gorduroso não alcoólico e / ou lipodistrofia
|
|
TWI748945B
(zh)
|
2015-03-13 |
2021-12-11 |
德商賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患治療
|
|
TW201705975A
(zh)
|
2015-03-18 |
2017-02-16 |
賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患之治療
|
|
EP3283507B8
(en)
|
2015-04-16 |
2019-11-13 |
Zealand Pharma A/S |
Acylated glucagon analogue
|
|
WO2016191395A1
(en)
|
2015-05-22 |
2016-12-01 |
The Bot Of The Leland Stanford Junior University |
Treatment of post-bariatric hypoglycemia with exendin(9-39)
|
|
RU2730996C2
(ru)
|
2015-06-03 |
2020-08-26 |
Интарсия Терапьютикс, Инк. |
Системы установки и извлечения имплантата
|
|
AR105319A1
(es)
|
2015-06-05 |
2017-09-27 |
Sanofi Sa |
Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
|
|
AR105284A1
(es)
|
2015-07-10 |
2017-09-20 |
Sanofi Sa |
Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
|
|
WO2017058482A1
(en)
*
|
2015-10-01 |
2017-04-06 |
Schlumberger Technology Corporation |
Active damping for nmr logging tools
|
|
SG11201802777XA
(en)
|
2015-10-14 |
2018-05-30 |
X Therma Inc |
Compositions and methods for reducing ice crystal formation
|
|
TN2018000225A1
(en)
|
2015-12-23 |
2019-10-04 |
Amgen Inc |
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
|
|
US10653753B2
(en)
|
2016-03-04 |
2020-05-19 |
Eiger Biopharmaceuticals, Inc. |
Treatment of hyperinsulinemic hypoglycemia with exendin-4 derivatives
|
|
WO2017181007A1
(en)
*
|
2016-04-15 |
2017-10-19 |
Robert Doyle |
Peptide drug improvement using vitamin b12 and haptocorrin binding substrate conjugates
|
|
EP3448885A4
(en)
|
2016-04-26 |
2020-01-08 |
R.P. Scherer Technologies, LLC |
ANTIBODY CONJUGATES AND METHODS OF MAKING AND USING SAME
|
|
WO2017200943A1
(en)
|
2016-05-16 |
2017-11-23 |
Intarcia Therapeutics, Inc. |
Glucagon-receptor selective polypeptides and methods of use thereof
|
|
USD860451S1
(en)
|
2016-06-02 |
2019-09-17 |
Intarcia Therapeutics, Inc. |
Implant removal tool
|
|
USD840030S1
(en)
|
2016-06-02 |
2019-02-05 |
Intarcia Therapeutics, Inc. |
Implant placement guide
|
|
EP3515408A1
(en)
|
2016-09-23 |
2019-07-31 |
Delpor, Inc. |
Stable compositions for incretin mimetic compounds
|
|
CA3038185A1
(en)
|
2016-10-14 |
2018-04-19 |
Tes Pharma S.R.L. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
|
SI3541366T1
(sl)
|
2016-11-21 |
2025-05-30 |
Amylyx Pharmaceuticals, Inc. |
Zapufrane formulacije eksendina (9-39)
|
|
EP3551202B1
(en)
|
2016-12-06 |
2024-01-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of enhancing the potency of incretin-based drugs in subjects in need thereof
|
|
EP4424320A3
(en)
|
2016-12-09 |
2025-06-11 |
Zealand Pharma A/S |
Acylated glp-1/glp-2 dual agonists
|
|
JP7286542B2
(ja)
|
2017-01-03 |
2023-06-05 |
インターシア セラピューティクス,インコーポレイティド |
Glp-1受容体アゴニストの持続的投与及び薬物の同時投与を含む方法
|
|
JOP20190177A1
(ar)
|
2017-01-17 |
2019-07-16 |
Amgen Inc |
طريقة لعلاج أو تحسين اضطرابات أيضية باستخدام مساعدات مستقبل glp-1 مقترنة بمناهضات لمستقبل ببتيد مثبط معوي (gipr)
|
|
BR112019020485A2
(pt)
|
2017-04-03 |
2020-05-12 |
Coherus Biosciences, Inc. |
Agonista ppary para tratamento de paralisia supranuclear progressiva
|
|
CN110831969B
(zh)
|
2017-06-20 |
2024-06-21 |
安进公司 |
使用抑胃肽受体(gipr)结合蛋白与glp-1激动剂的组合治疗或改善代谢障碍的方法
|
|
PL3474820T3
(pl)
|
2017-08-24 |
2024-05-13 |
Novo Nordisk A/S |
Kompozycje glp-1 i ich zastosowania
|
|
ES2928207T3
(es)
|
2018-04-10 |
2022-11-16 |
Sanofi Aventis Deutschland |
Síntesis de lixisenatida con encapuchado
|
|
CA3096493A1
(en)
|
2018-04-10 |
2019-10-17 |
Sanofi-Aventis Deutschland Gmbh |
Method for cleavage of solid phase-bound peptides from the solid phase
|
|
EP3883930A1
(en)
|
2018-11-20 |
2021-09-29 |
Tes Pharma S.r.l. |
Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
|
|
MX2021010737A
(es)
|
2019-03-08 |
2021-09-28 |
Amgen Inc |
Terapia de combinacion por factor de diferenciacion del crecimiento 15.
|
|
EP4106724A1
(en)
|
2020-02-18 |
2022-12-28 |
Novo Nordisk A/S |
Glp-1 compositions and uses thereof
|
|
WO2024123812A1
(en)
|
2022-12-05 |
2024-06-13 |
Shattuck Labs, Inc. |
Fusion proteins for the treatment of cardiometabolic diseases
|