FI912851A0 - Cykliska amidderivat. - Google Patents
Cykliska amidderivat.Info
- Publication number
- FI912851A0 FI912851A0 FI912851A FI912851A FI912851A0 FI 912851 A0 FI912851 A0 FI 912851A0 FI 912851 A FI912851 A FI 912851A FI 912851 A FI912851 A FI 912851A FI 912851 A0 FI912851 A0 FI 912851A0
- Authority
- FI
- Finland
- Prior art keywords
- aryl
- cyclic amide
- integer
- amide compound
- cyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI955001A FI955001A (fi) | 1990-06-15 | 1995-10-19 | Sykliset aminojohdannaiset |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15713490 | 1990-06-15 | ||
| JP15713490 | 1990-06-15 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI912851A0 true FI912851A0 (fi) | 1991-06-13 |
| FI912851A FI912851A (fi) | 1991-12-16 |
| FI114797B FI114797B (fi) | 2004-12-31 |
Family
ID=15642948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI912851A FI114797B (fi) | 1990-06-15 | 1991-06-13 | Menetelmä lääkeaineena käyttökelpoisen syklisen amidijohdannaisen valmistamiseksi |
Country Status (17)
| Country | Link |
|---|---|
| US (6) | US5292735A (fi) |
| EP (3) | EP0468187B1 (fi) |
| JP (2) | JP2807577B2 (fi) |
| KR (1) | KR940004391B1 (fi) |
| CN (1) | CN1045206C (fi) |
| AT (3) | ATE209198T1 (fi) |
| AU (2) | AU653938B2 (fi) |
| CA (2) | CA2175502C (fi) |
| DE (3) | DE69132827T2 (fi) |
| DK (2) | DK0677516T3 (fi) |
| ES (2) | ES2123858T3 (fi) |
| FI (1) | FI114797B (fi) |
| HU (2) | HU216188B (fi) |
| NO (1) | NO180540B1 (fi) |
| NZ (2) | NZ272015A (fi) |
| PT (1) | PT97993B (fi) |
| ZA (1) | ZA914423B (fi) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| FR2677019B1 (fr) * | 1991-05-27 | 1994-11-25 | Pf Medicament | Nouvelles piperidines disubstituees-1,4, leur preparation et leur application en therapeutique. |
| US5462934A (en) * | 1992-03-09 | 1995-10-31 | Takeda Chemical Industries | Condensed heterocyclic ketone derivatives and their use |
| DE69330272T2 (de) * | 1992-04-23 | 2001-10-25 | Merrell Pharma Inc | 4-imidomethyl-1-[2'-phenyl-2-oxoethyl]-piperidine als serotonin-5ht2-antagonisten, ihre herstellung und therapeutische anwendung |
| EP0567090B1 (en) | 1992-04-24 | 2000-07-26 | Takeda Chemical Industries, Ltd. | Benzoxazepine derivatives as cholinesterase inhibitors |
| US5624926A (en) * | 1993-02-18 | 1997-04-29 | Kyowa Hakko Kogyo Co., Ltd. | Piperidinyl-dioxoquinazolines as adenosine reuptake inhibitors |
| US5869499A (en) * | 1993-07-15 | 1999-02-09 | Pfizer Inc | Benzyloxyquinuclidines as substance P antagonists |
| ATE180780T1 (de) * | 1993-08-05 | 1999-06-15 | Hoechst Marion Roussel Inc | 2-(piperidin-4-yl, pyridin-4-yl und tetrahydropyridin-4-yl)-benzofuran-7-carbamat derivate, ihre herstellung und verwendung als acetylcholinesterase inhibitoren |
| FR2750991A1 (fr) * | 1996-07-12 | 1998-01-16 | Pf Medicament | Nouveaux benzodioxannes et 1-(2h)-benzopyrannes, leur preparation et leur utilisation comme medicament |
| FR2752732B1 (fr) | 1996-08-28 | 1998-11-20 | Pf Medicament | Forme galenique a liberation prolongee de milnacipran |
| DE19708846A1 (de) * | 1997-03-05 | 1998-09-17 | Gruenenthal Gmbh | Neue Benzoxazindionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung |
| CN1535682A (zh) | 1998-09-30 | 2004-10-13 | ����ҩƷ��ҵ��ʽ���� | 改善膀胱排泄能力的药物 |
| US20040192669A1 (en) | 2000-04-13 | 2004-09-30 | Rosenfeld Mark J. | Novel compounds for use in weight loss and appetite suppression in humans |
| US7794761B2 (en) * | 2000-04-13 | 2010-09-14 | Seroctin Research & Technology, Inc. | Methods for inducing anti-anxiety and calming effects in animals and humans |
| US7220735B2 (en) * | 2002-04-18 | 2007-05-22 | Schering Corporation | Benzimidazolone histamine H3 antagonists |
| US7524877B2 (en) | 2003-11-20 | 2009-04-28 | Seroctin Research & Technology, Inc. | Compounds for use in weight loss and appetite suppression in humans |
| GB0507695D0 (en) * | 2005-04-15 | 2005-05-25 | Novartis Ag | Organic compounds |
| JP2009531323A (ja) * | 2006-03-20 | 2009-09-03 | カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ | アセチルコリンエステラーゼ阻害剤として有用な薬剤組成物 |
| US8278302B2 (en) * | 2009-04-08 | 2012-10-02 | Boehringer Ingelheim International Gmbh | Substituted piperidines as CCR3 antagonists |
| JP6082250B2 (ja) | 2010-02-09 | 2017-02-15 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 認知機能を改善するための方法および組成物 |
| UA109290C2 (uk) | 2010-10-07 | 2015-08-10 | Спільні кристали і солі інгібіторів ccr3 | |
| US9145372B2 (en) | 2010-11-15 | 2015-09-29 | Agenebio, Inc. | Pyridazine derivatives, compositions and methods for treating cognitive impairment |
| AR090566A1 (es) | 2012-04-02 | 2014-11-19 | Boehringer Ingelheim Int | Proceso para la produccion de inhibidores de crr |
| US10213421B2 (en) | 2012-04-04 | 2019-02-26 | Alkahest, Inc. | Pharmaceutical formulations comprising CCR3 antagonists |
| WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| EP2968220B1 (en) | 2013-03-15 | 2021-05-05 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| CN103224498B (zh) * | 2013-05-07 | 2015-10-28 | 陈定奔 | 两种唑并喹唑啉酮稠杂环的新合成方法 |
| CA3123897C (en) | 2013-12-20 | 2024-02-06 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| PL3102576T3 (pl) | 2014-02-03 | 2019-12-31 | Vitae Pharmaceuticals, Llc | Dihydropirolopirydynowe inhibitory ror-gamma |
| UA118989C2 (uk) | 2014-10-14 | 2019-04-10 | Вітае Фармасьютікалс, Інк. | Дигідропіролопіридинові інгібітори ror-гамма |
| US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| US9845308B2 (en) | 2014-11-05 | 2017-12-19 | Vitae Pharmaceuticals, Inc. | Isoindoline inhibitors of ROR-gamma |
| CA2986598C (en) | 2015-05-22 | 2023-09-26 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| CA2990004C (en) | 2015-06-19 | 2024-04-23 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| WO2017024018A1 (en) | 2015-08-05 | 2017-02-09 | Vitae Pharmaceuticals, Inc. | Modulators of ror-gamma |
| WO2017087608A1 (en) | 2015-11-20 | 2017-05-26 | Vitae Pharmaceuticals, Inc. | Modulators of ror-gamma |
| TWI757266B (zh) | 2016-01-29 | 2022-03-11 | 美商維它藥物有限責任公司 | ＲＯＲ－γ調節劑 |
| US9481674B1 (en) | 2016-06-10 | 2016-11-01 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
| US20180170941A1 (en) | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
| IL298639A (en) | 2017-07-24 | 2023-01-01 | Vitae Pharmaceuticals Llc | Inhibitors of gamma ror |
| CN108623610B (zh) * | 2018-06-04 | 2020-08-11 | 中国科学院化学研究所 | 一种氮杂*酮化合物及其制备方法 |
| JP2021528427A (ja) | 2018-06-19 | 2021-10-21 | エージンバイオ， インコーポレイテッド | 認知障害を処置するためのベンゾジアゼピン誘導体、組成物および方法 |
| CN108658887B (zh) * | 2018-06-20 | 2022-04-05 | 中南大学 | 苯并[d][1,3]噁嗪-2,4(1H)-二酮衍生物及其合成方法和用途 |
| WO2024039886A1 (en) | 2022-08-19 | 2024-02-22 | Agenebio, Inc. | Benzazepine derivatives, compositions, and methods for treating cognitive impairment |
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| JP2699511B2 (ja) * | 1988-01-29 | 1998-01-19 | 武田薬品工業株式会社 | 置換アミン類 |
| FI892362A (fi) * | 1988-06-01 | 1989-12-02 | Eisai Co Ltd | Buten- eller propensyraderivat. |
| FR2640266B2 (fr) * | 1988-07-12 | 1992-07-10 | Synthelabo | Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique |
| FR2636065B1 (fr) * | 1988-09-08 | 1993-05-07 | Fabre Sa Pierre | Nouveaux derives de dihydro-2,3 arylacoylaminoalcoyl-3 4h-benzoxazine-1,3 ones-4, leur preparation et leur application en tant que medicaments utiles en therapeutique |
| US4910302A (en) * | 1988-12-19 | 1990-03-20 | American Home Products Corporation | Psychotropic polycyclic imides |
| JP2777159B2 (ja) * | 1988-12-22 | 1998-07-16 | エーザイ株式会社 | 環状アミン誘導体を含有する医薬 |
| JPH02193992A (ja) * | 1989-01-23 | 1990-07-31 | Kyowa Hakko Kogyo Co Ltd | キナゾリン誘導体 |
| IL93473A0 (en) * | 1989-02-28 | 1990-11-29 | Pfizer | Antiinflammatory benzoxazolones |
| JP2747013B2 (ja) * | 1989-05-19 | 1998-05-06 | エーザイ株式会社 | ブテン酸又はプロペン酸誘導体 |
| JP2725378B2 (ja) * | 1989-05-29 | 1998-03-11 | 武田薬品工業株式会社 | カルバミド酸エステル誘導体 |
| EP0497843A4 (en) * | 1989-10-27 | 1992-09-23 | The Du Pont Merck Pharmaceutical Company | (n-phthalimidoalkyl) piperidines |
| TW197442B (fi) * | 1990-02-08 | 1993-01-01 | Pfizer | |
| DK37790A (da) * | 1990-02-13 | 1991-08-14 | Novo Nordisk As | Indolderivater, deres fremstilling og anvendelse |
| FR2660657B1 (fr) * | 1990-04-09 | 1993-05-07 | Adir | Nouveaux derives du 3-aminochromane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| EP0626373B1 (en) * | 1993-05-26 | 1998-12-23 | Sumitomo Pharmaceuticals Company, Limited | Quinazolinone derivatives |
-
1991
- 1991-05-22 JP JP3117420A patent/JP2807577B2/ja not_active Expired - Lifetime
- 1991-06-03 AU AU78136/91A patent/AU653938B2/en not_active Expired
- 1991-06-10 KR KR91009534A patent/KR940004391B1/ko not_active IP Right Cessation
- 1991-06-10 ZA ZA914423A patent/ZA914423B/xx unknown
- 1991-06-12 NO NO19912252A patent/NO180540B1/no not_active IP Right Cessation
- 1991-06-13 CA CA002175502A patent/CA2175502C/en not_active Expired - Lifetime
- 1991-06-13 DE DE69132827T patent/DE69132827T2/de not_active Expired - Lifetime
- 1991-06-13 EP EP91109708A patent/EP0468187B1/en not_active Expired - Lifetime
- 1991-06-13 AT AT96109320T patent/ATE209198T1/de not_active IP Right Cessation
- 1991-06-13 EP EP95108191A patent/EP0677516B1/en not_active Expired - Lifetime
- 1991-06-13 DK DK95108191T patent/DK0677516T3/da active
- 1991-06-13 NZ NZ272015A patent/NZ272015A/xx not_active IP Right Cessation
- 1991-06-13 CA CA002044515A patent/CA2044515C/en not_active Expired - Lifetime
- 1991-06-13 ES ES95108191T patent/ES2123858T3/es not_active Expired - Lifetime
- 1991-06-13 DE DE69129090T patent/DE69129090T2/de not_active Expired - Lifetime
- 1991-06-13 DE DE69130120T patent/DE69130120T2/de not_active Expired - Lifetime
- 1991-06-13 AT AT95108191T patent/ATE170517T1/de not_active IP Right Cessation
- 1991-06-13 DK DK91109708T patent/DK0468187T3/da active
- 1991-06-13 EP EP96109320A patent/EP0742216B1/en not_active Expired - Lifetime
- 1991-06-13 NZ NZ238534A patent/NZ238534A/en not_active IP Right Cessation
- 1991-06-13 FI FI912851A patent/FI114797B/fi not_active IP Right Cessation
- 1991-06-13 AT AT91109708T patent/ATE164156T1/de not_active IP Right Cessation
- 1991-06-13 ES ES91109708T patent/ES2113355T3/es not_active Expired - Lifetime
- 1991-06-14 US US07/715,754 patent/US5292735A/en not_active Expired - Lifetime
- 1991-06-14 PT PT97993A patent/PT97993B/pt not_active IP Right Cessation
- 1991-06-14 HU HU911986A patent/HU216188B/hu unknown
- 1991-06-15 CN CN91104087A patent/CN1045206C/zh not_active Expired - Lifetime
-
1993
- 1993-12-13 US US08/165,490 patent/US5504088A/en not_active Expired - Lifetime
-
1995
- 1995-01-18 AU AU10246/95A patent/AU680704B2/en not_active Expired
- 1995-05-25 US US08/451,068 patent/US5919778A/en not_active Expired - Lifetime
- 1995-05-25 US US08/449,739 patent/US5620976A/en not_active Expired - Lifetime
- 1995-05-25 US US08/449,749 patent/US5521182A/en not_active Expired - Lifetime
- 1995-05-25 US US08/449,738 patent/US5654308A/en not_active Expired - Lifetime
- 1995-06-30 HU HU95P/P00611P patent/HU211895A9/hu unknown
- 1995-09-11 JP JP23238195A patent/JP3224187B2/ja not_active Expired - Lifetime
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| PC | Transfer of assignment of patent |
Owner name: EISAI R&D MANAGEMENT CO., LTD. Free format text: EISAI R&D MANAGEMENT CO., LTD. |
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| MA | Patent expired |