ATE133955T1 - Acylphosphatester und modifikation von proteinen damit - Google Patents

Acylphosphatester und modifikation von proteinen damit

Info

Publication number
ATE133955T1
ATE133955T1 AT91905433T AT91905433T ATE133955T1 AT E133955 T1 ATE133955 T1 AT E133955T1 AT 91905433 T AT91905433 T AT 91905433T AT 91905433 T AT91905433 T AT 91905433T AT E133955 T1 ATE133955 T1 AT E133955T1
Authority
AT
Austria
Prior art keywords
esters
image
acylphosphate
modification
alkenyl
Prior art date
Application number
AT91905433T
Other languages
English (en)
Inventor
Ronald H Kluger
Andrew S Grant
Original Assignee
Univ Toronto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Toronto filed Critical Univ Toronto
Application granted granted Critical
Publication of ATE133955T1 publication Critical patent/ATE133955T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/095—Compounds containing the structure P(=O)-O-acyl, P(=O)-O-heteroatom, P(=O)-O-CN
    • C07F9/096—Compounds containing the structure P(=O)-O-C(=X)- (X = O, S, Se)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT91905433T 1990-03-14 1991-03-12 Acylphosphatester und modifikation von proteinen damit ATE133955T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49352490A 1990-03-14 1990-03-14

Publications (1)

Publication Number Publication Date
ATE133955T1 true ATE133955T1 (de) 1996-02-15

Family

ID=23960593

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91905433T ATE133955T1 (de) 1990-03-14 1991-03-12 Acylphosphatester und modifikation von proteinen damit

Country Status (10)

Country Link
US (1) US5334707A (de)
EP (1) EP0519953B1 (de)
JP (1) JP3021041B2 (de)
AT (1) ATE133955T1 (de)
AU (1) AU658821B2 (de)
CA (1) CA2078141C (de)
DE (1) DE69117054T2 (de)
DK (1) DK0519953T3 (de)
ES (1) ES2082971T3 (de)
WO (1) WO1991013891A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250665A (en) * 1991-05-31 1993-10-05 The University Of Toronto Innovations Foundation Specifically β-β cross-linked hemoglobins and method of preparation
WO1999033850A1 (en) * 1997-12-24 1999-07-08 Methylgene, Inc. NOVEL β-LACTAMASE AND DD-PEPTIDASE INHIBITORS
US6599889B2 (en) 1997-12-24 2003-07-29 Methylgere, Inc. Acyl phosphonate inhibitors of β-lactamases
JP5514973B2 (ja) * 2010-04-30 2014-06-04 独立行政法人産業技術総合研究所 ホスホン酸ジエステル誘導体の製造方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2625536A (en) * 1951-05-05 1953-01-13 Du Pont Neutral esters of dicarboxylic acid orthophosphoric acid mixed anhydrides and condensation polymerization process utilizing the same
US2748153A (en) * 1951-05-05 1956-05-29 Du Pont Preparation of acyl phosphoric esters
DE1044073B (de) * 1957-03-20 1958-11-20 Basf Ag Verfahren zur Herstellung von O, O-Dialkylphosphorsaeure- bzw. -thiophosphorsaeureverbindungen
US3835203A (en) * 1970-11-10 1974-09-10 Us Agriculture Phosphoric-carboxylic acid anhydrides
US4001200A (en) * 1975-02-27 1977-01-04 Alza Corporation Novel polymerized, cross-linked, stromal-free hemoglobin
US4001401A (en) * 1975-02-02 1977-01-04 Alza Corporation Blood substitute and blood plasma expander comprising polyhemoglobin
US4061736A (en) * 1975-02-02 1977-12-06 Alza Corporation Pharmaceutically acceptable intramolecularly cross-linked, stromal-free hemoglobin
US4053590A (en) * 1975-02-27 1977-10-11 Alza Corporation Compositions of matter comprising macromolecular hemoglobin
US4473496A (en) * 1981-09-14 1984-09-25 The United States Of America As Represented By The Secretary Of The Army Intramolecularly crosslinked hemoglobin
DE3144705C2 (de) * 1981-11-11 1983-12-08 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung eines lagerstabilen, vernetzten Hämoglobinpräparates mit hoher Sauerstoff-Transportkapazität, sowie das nach diesem Verfahren hergestellte Hämoglobinpräparat
US4529719A (en) * 1983-05-04 1985-07-16 Tye Ross W Modified crosslinked stroma-free tetrameric hemoglobin
GB8328917D0 (en) * 1983-10-28 1983-11-30 Fisons Plc Blood substitute
US4598064A (en) * 1984-06-27 1986-07-01 University Of Iowa Research Foundation Alpha-alpha cross-linked hemoglobins
US4600531A (en) * 1984-06-27 1986-07-15 University Of Iowa Research Foundation Production of alpha-alpha cross-linked hemoglobins in high yield
US4584130A (en) * 1985-03-29 1986-04-22 University Of Maryland Intramolecularly cross-linked hemoglobin and method of preparation
DE3675588D1 (de) * 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
GB8710598D0 (en) * 1987-05-05 1987-06-10 Star Medical Diagnostics Ltd Hemoglobin based blood substitute
GB8712240D0 (en) * 1987-05-23 1987-07-01 Fisons Plc Pharmaceutical formulation
IL87708A (en) * 1988-09-08 1994-04-12 Technion Inst For Research And Hemoglobin-based blood substitute possessing a colloid oncotic pressure substantially similar to human blood and method for the preparation thereof

Also Published As

Publication number Publication date
JP3021041B2 (ja) 2000-03-15
DE69117054D1 (de) 1996-03-21
AU7447791A (en) 1991-10-10
JPH05505604A (ja) 1993-08-19
US5334707A (en) 1994-08-02
EP0519953A1 (de) 1992-12-30
DK0519953T3 (da) 1996-07-01
EP0519953B1 (de) 1996-02-07
WO1991013891A1 (en) 1991-09-19
DE69117054T2 (de) 1996-06-27
ES2082971T3 (es) 1996-04-01
CA2078141A1 (en) 1991-09-15
AU658821B2 (en) 1995-05-04
CA2078141C (en) 1996-10-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee