NO912252A - Fremgangsmaate for fremstilling av terapeutisk aktive sykliske amidderivater. - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive sykliske amidderivater.

Info

Publication number
NO912252A
NO912252A NO91912252A NO912252A NO912252A NO 912252 A NO912252 A NO 912252A NO 91912252 A NO91912252 A NO 91912252A NO 912252 A NO912252 A NO 912252A NO 912252 A NO912252 A NO 912252A
Authority
NO
Norway
Prior art keywords
cyclic amide
aryl
procedure
preparation
amide derivatives
Prior art date
Application number
NO91912252A
Other languages
English (en)
Other versions
NO180540C (no
NO912252D0 (no
NO180540B (no
NO180540B1 (no
Inventor
Hachiro Sugimoto
Masahiro Yonaga
Norio Karibe
Youichi Iimura
Satoshi Nagato
Atsushi Sasaki
Yoshiharu Yamanishi
Hiroo Ogura
Takashi Kosasa
Kumi Uchikoshi
Kiyomi Yamatsu
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of NO912252D0 publication Critical patent/NO912252D0/no
Publication of NO912252A publication Critical patent/NO912252A/no
Priority to NO19954229A priority Critical patent/NO307089B1/no
Publication of NO180540B publication Critical patent/NO180540B/no
Publication of NO180540C publication Critical patent/NO180540C/no
Publication of NO180540B1 publication Critical patent/NO180540B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
NO19912252A 1990-06-15 1991-06-12 Analogifremgangsmate for fremstilling av terapeutisk aktiv cyklisk amidderivat NO180540B1 (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO19954229A NO307089B1 (no) 1990-06-15 1995-10-23 Analogifremgangsmate for fremstilling av terapeutisk aktive cykliske amidderivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15713490 1990-06-15

Publications (5)

Publication Number Publication Date
NO912252D0 NO912252D0 (no) 1991-06-12
NO912252A true NO912252A (no) 1991-12-16
NO180540B NO180540B (no) 1997-01-27
NO180540C NO180540C (no) 1997-05-07
NO180540B1 NO180540B1 (no) 1997-05-26

Family

ID=15642948

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19912252A NO180540B1 (no) 1990-06-15 1991-06-12 Analogifremgangsmate for fremstilling av terapeutisk aktiv cyklisk amidderivat

Country Status (17)

Country Link
US (6) US5292735A (no)
EP (3) EP0468187B1 (no)
JP (2) JP2807577B2 (no)
KR (1) KR940004391B1 (no)
CN (1) CN1045206C (no)
AT (3) ATE209198T1 (no)
AU (2) AU653938B2 (no)
CA (2) CA2044515C (no)
DE (3) DE69132827T2 (no)
DK (2) DK0468187T3 (no)
ES (2) ES2123858T3 (no)
FI (1) FI114797B (no)
HU (2) HU216188B (no)
NO (1) NO180540B1 (no)
NZ (2) NZ238534A (no)
PT (1) PT97993B (no)
ZA (1) ZA914423B (no)

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ES2113355T3 (es) 1998-05-01
DE69130120D1 (de) 1998-10-08
EP0468187A3 (en) 1992-04-15
EP0742216B1 (en) 2001-11-21
ATE164156T1 (de) 1998-04-15
HU911986D0 (en) 1991-12-30
DE69132827T2 (de) 2002-06-27
EP0677516B1 (en) 1998-09-02
US5919778A (en) 1999-07-06
HU211895A9 (en) 1995-12-28
JP2807577B2 (ja) 1998-10-08
ZA914423B (en) 1992-03-25
US5620976A (en) 1997-04-15
DE69129090T2 (de) 1998-08-06
AU1024695A (en) 1995-03-30
DE69130120T2 (de) 1999-02-18
DE69129090D1 (de) 1998-04-23
EP0742216A2 (en) 1996-11-13
ES2123858T3 (es) 1999-01-16
CN1057262A (zh) 1991-12-25
PT97993A (pt) 1992-03-31
NO180540C (no) 1997-05-07
AU653938B2 (en) 1994-10-20
NZ272015A (en) 1999-07-29
AU7813691A (en) 1991-12-19
KR940004391B1 (en) 1994-05-25
PT97993B (pt) 1998-11-30
NO912252D0 (no) 1991-06-12
EP0677516A1 (en) 1995-10-18
US5521182A (en) 1996-05-28
FI114797B (fi) 2004-12-31
HUT61742A (en) 1993-03-01
DK0468187T3 (da) 1999-01-11
EP0468187B1 (en) 1998-03-18
DK0677516T3 (da) 1999-06-07
CN1045206C (zh) 1999-09-22
CA2044515C (en) 1997-05-20
ATE209198T1 (de) 2001-12-15
CA2175502A1 (en) 1991-12-16
CA2044515A1 (en) 1991-12-16
HU216188B (hu) 1999-05-28
US5654308A (en) 1997-08-05
EP0742216A3 (en) 1997-05-28
JP3224187B2 (ja) 2001-10-29
FI912851A0 (fi) 1991-06-13
US5504088A (en) 1996-04-02
JPH04235161A (ja) 1992-08-24
US5292735A (en) 1994-03-08
NO180540B (no) 1997-01-27
AU680704B2 (en) 1997-08-07
ATE170517T1 (de) 1998-09-15
EP0468187A2 (en) 1992-01-29
NO180540B1 (no) 1997-05-26
KR920000754A (ko) 1992-01-29
DE69132827D1 (de) 2002-01-03
JPH0899974A (ja) 1996-04-16
NZ238534A (en) 1995-07-26
FI912851A (fi) 1991-12-16
CA2175502C (en) 2001-07-10

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