DE68917357D1 - Derivate der Coffeinsäure und pharmazeutische Zusammensetzungen, die sie enthalten. - Google Patents

Derivate der Coffeinsäure und pharmazeutische Zusammensetzungen, die sie enthalten.

Info

Publication number
DE68917357D1
DE68917357D1 DE68917357T DE68917357T DE68917357D1 DE 68917357 D1 DE68917357 D1 DE 68917357D1 DE 68917357 T DE68917357 T DE 68917357T DE 68917357 T DE68917357 T DE 68917357T DE 68917357 D1 DE68917357 D1 DE 68917357D1
Authority
DE
Germany
Prior art keywords
derivatives
pharmaceutical compositions
compositions containing
hydrogen atom
caffeine acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68917357T
Other languages
English (en)
Other versions
DE68917357T2 (de
Inventor
Hidetsura Cho
Masaru Ueda
Mie Tamaoka
Mikiko Hamaguchi
Seiitsu Murota
Ikuo Morita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP63106274A external-priority patent/JP2557090B2/ja
Priority claimed from JP5586789A external-priority patent/JP2647185B2/ja
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of DE68917357D1 publication Critical patent/DE68917357D1/de
Publication of DE68917357T2 publication Critical patent/DE68917357T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/34—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring with cyano groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by unsaturated carbon chains
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
DE68917357T 1988-04-28 1989-04-28 Derivate der Coffeinsäure und pharmazeutische Zusammensetzungen, die sie enthalten. Expired - Fee Related DE68917357T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63106274A JP2557090B2 (ja) 1988-04-28 1988-04-28 カフェー酸誘導体およびそれを含む医薬組成物
JP5586789A JP2647185B2 (ja) 1989-03-08 1989-03-08 カフェー酸誘導体及びそれを含む医薬組成物

Publications (2)

Publication Number Publication Date
DE68917357D1 true DE68917357D1 (de) 1994-09-15
DE68917357T2 DE68917357T2 (de) 1995-01-26

Family

ID=26396766

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68917357T Expired - Fee Related DE68917357T2 (de) 1988-04-28 1989-04-28 Derivate der Coffeinsäure und pharmazeutische Zusammensetzungen, die sie enthalten.

Country Status (6)

Country Link
US (1) US5063243A (de)
EP (1) EP0339671B1 (de)
KR (1) KR900016098A (de)
AT (1) ATE109770T1 (de)
AU (1) AU618595B2 (de)
DE (1) DE68917357T2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283352A (en) * 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
US5217999A (en) 1987-12-24 1993-06-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Styryl compounds which inhibit EGF receptor protein tyrosine kinase
AU632992B2 (en) * 1987-12-24 1993-01-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem Pharmaceutical compositions comprising benzylidene- and cinnamylidene-malononitrile derivatives for the inhibition of proliferative processes in mammalian cells, certain such novel compounds and their preparation
GB2238047B (en) * 1989-11-03 1993-02-10 Orion Yhtymae Oy Stable polymorphic form of (e)-n,n-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide and the process for its preparation
JPH05331129A (ja) * 1990-08-30 1993-12-14 Suntory Ltd カフェー酸誘導体及びそれを含む医薬組成物
JPH05301838A (ja) * 1991-10-15 1993-11-16 Mitsubishi Kasei Corp スチレン誘導体
US5981569A (en) * 1992-11-13 1999-11-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Substituted phenylacrylonitrile compounds and compositions thereof for the treatment of disease
AU3905599A (en) * 1998-05-20 1999-12-06 City Of Hope Method of treating or preventing abnormal cardiac cell growth by inhibiting the 12-lipoxygenase pathway
US6602515B2 (en) 2001-07-16 2003-08-05 Em Industries Photo stable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom
US6831191B2 (en) 2001-12-20 2004-12-14 Em Industries Photo stable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom
US6699463B2 (en) 2002-04-10 2004-03-02 Em Industries Photostable cationic organic sunscreen compounds with antioxidant properties and compositions obtained therefrom
JP4412173B2 (ja) 2002-08-14 2010-02-10 日産化学工業株式会社 トロンボポエチンレセプター活性化剤ならびにそれらの製造方法
US6936735B2 (en) * 2002-08-27 2005-08-30 Emd Chemicals, Inc. Photostable cationic organic sunscreen compounds and compositions obtained therefrom
WO2011137363A1 (en) * 2010-04-30 2011-11-03 Allergan, Inc. Novel treatment for age related macular degeneration and ocular ischemic disease associated with complement activation by targeting 5-lipoxygenase
US10214476B2 (en) * 2011-12-30 2019-02-26 Ecole Nationale Superieure De Chimie De Clermont Ferrand Pain relief compounds
CN113816875A (zh) * 2021-10-26 2021-12-21 北京瑞固科技发展有限公司 材料单体及其制备方法与应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892777A (en) * 1968-05-01 1975-07-01 Hoffmann La Roche Substituted benzylethylenedicarbamates
US3855301A (en) * 1971-06-28 1974-12-17 Procter & Gamble Novel dihydrochalcone and process
IL38412A (en) * 1971-12-20 1977-02-28 Plantex Ltd Alpha-cyano-3,4,5-trialkoxycinnamic acid derivatives
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
AU632992B2 (en) * 1987-12-24 1993-01-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem Pharmaceutical compositions comprising benzylidene- and cinnamylidene-malononitrile derivatives for the inhibition of proliferative processes in mammalian cells, certain such novel compounds and their preparation

Also Published As

Publication number Publication date
DE68917357T2 (de) 1995-01-26
US5063243A (en) 1991-11-05
AU618595B2 (en) 1992-01-02
EP0339671A2 (de) 1989-11-02
EP0339671A3 (de) 1991-05-15
KR900016098A (ko) 1990-11-12
AU3381389A (en) 1989-11-02
ATE109770T1 (de) 1994-08-15
EP0339671B1 (de) 1994-08-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee