ATE87004T1 - Fluor enthaltende makrolid-verbindungen, pharmazeutische zusammensetzungen, welche diese enthalten und ihre verwendung fuer die herstellung von arzneimitteln. - Google Patents
Fluor enthaltende makrolid-verbindungen, pharmazeutische zusammensetzungen, welche diese enthalten und ihre verwendung fuer die herstellung von arzneimitteln.Info
- Publication number
- ATE87004T1 ATE87004T1 AT87119019T AT87119019T ATE87004T1 AT E87004 T1 ATE87004 T1 AT E87004T1 AT 87119019 T AT87119019 T AT 87119019T AT 87119019 T AT87119019 T AT 87119019T AT E87004 T1 ATE87004 T1 AT E87004T1
- Authority
- AT
- Austria
- Prior art keywords
- fluorine
- manufacture
- pharmaceutical compositions
- hydrogen
- medicinal products
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 239000003120 macrolide antibiotic agent Substances 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 4
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 abstract 3
- 229910052731 fluorine Inorganic materials 0.000 abstract 3
- 239000011737 fluorine Substances 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30713286 | 1986-12-22 | ||
| EP87119019A EP0273357B1 (de) | 1986-12-22 | 1987-12-22 | Fluor enthaltende Makrolid-Verbindungen, pharmazeutische Zusammensetzungen, welche diese enthalten und ihre Verwendung für die Herstellung von Arzneimitteln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE87004T1 true ATE87004T1 (de) | 1993-04-15 |
Family
ID=17965413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87119019T ATE87004T1 (de) | 1986-12-22 | 1987-12-22 | Fluor enthaltende makrolid-verbindungen, pharmazeutische zusammensetzungen, welche diese enthalten und ihre verwendung fuer die herstellung von arzneimitteln. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4876245A (de) |
| EP (1) | EP0273357B1 (de) |
| AT (1) | ATE87004T1 (de) |
| AU (1) | AU599181B2 (de) |
| DE (1) | DE3784883T2 (de) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1195299B (it) * | 1981-11-27 | 1988-10-12 | Pierrel Spa | Procedimento chimico di sintesi per la preparazione di antibiotici macrolidici |
| IT1163796B (it) * | 1983-07-18 | 1987-04-08 | Pierrel Spa | Procedimento per la preparazione di (8s)-8-fluoroeritromicina |
| IT1196041B (it) * | 1984-03-08 | 1988-11-10 | Pierrel Spa | Emichetali di (8s)-8-fluoroeritromicine,il procedimento per la loro preparazione e le formulazioni adatte alla somministrazione orale che contengono i prodotti |
| JPS6185378A (ja) * | 1984-10-02 | 1986-04-30 | Daikin Ind Ltd | ８−フルオロエリスロノライド誘導体の製法 |
-
1987
- 1987-12-21 US US07/136,125 patent/US4876245A/en not_active Expired - Lifetime
- 1987-12-22 EP EP87119019A patent/EP0273357B1/de not_active Expired - Lifetime
- 1987-12-22 DE DE8787119019T patent/DE3784883T2/de not_active Expired - Fee Related
- 1987-12-22 AU AU82927/87A patent/AU599181B2/en not_active Ceased
- 1987-12-22 AT AT87119019T patent/ATE87004T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU8292787A (en) | 1988-06-23 |
| DE3784883D1 (de) | 1993-04-22 |
| EP0273357B1 (de) | 1993-03-17 |
| US4876245A (en) | 1989-10-24 |
| AU599181B2 (en) | 1990-07-12 |
| EP0273357A3 (en) | 1989-11-02 |
| EP0273357A2 (de) | 1988-07-06 |
| DE3784883T2 (de) | 1993-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |