ES8801656A1 - Un procedimiento para la preparacion de un compuesto de quinazolinona. - Google Patents

Un procedimiento para la preparacion de un compuesto de quinazolinona.

Info

Publication number
ES8801656A1
ES8801656A1 ES555761A ES555761A ES8801656A1 ES 8801656 A1 ES8801656 A1 ES 8801656A1 ES 555761 A ES555761 A ES 555761A ES 555761 A ES555761 A ES 555761A ES 8801656 A1 ES8801656 A1 ES 8801656A1
Authority
ES
Spain
Prior art keywords
hydrogen atom
preparation
lower alkyl
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555761A
Other languages
English (en)
Other versions
ES555761A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of ES8801656A1 publication Critical patent/ES8801656A1/es
Publication of ES555761A0 publication Critical patent/ES555761A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UN COMPUESTO DE QUINAZOLINONA, DE FORMULA GENERAL (II) EN PRESENCIA DE UN ACIDO Y DE UN DISOLVENTE Y A UNA TEMPERATURA COMPRENDIDA ENTRE LOS 20 GRADOS Y LOS 250. EN DICHAS FORMULAS R1 ES UN GRUPO ALQUILO INFERIOR, UN GRUPO FENILO SUSTITUIDO O NO SUSTITUIDO O UN GRUPO ARALQUILO; R2, R3, R4 Y R5 SON IGUALES O DIFERENTES Y CADA UNO DE ELLOS REPRESENTA UN ATOMO DE HIDROGENO, UN ATOMO DE HALOGENO, UN GRUPO ALQUILO INFERIOR O UN GRUPO ALCOXI INFERIOR; W ES UN RADICAL; Y R6 ES ALQUILO INFERIOR. DE APLICACION EN LA PROFILAXIS Y EL TRATAMIENTO DE VARIAS COMPLICACIONES DE LA DIABETES.
ES555761A 1985-06-06 1986-06-05 Un procedimiento para la preparacion de un compuesto de quinazolinona. Expired ES8801656A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12400885 1985-06-06
JP23416085 1985-10-18

Publications (2)

Publication Number Publication Date
ES8801656A1 true ES8801656A1 (es) 1988-02-16
ES555761A0 ES555761A0 (es) 1988-02-16

Family

ID=26460779

Family Applications (2)

Application Number Title Priority Date Filing Date
ES555761A Expired ES8801656A1 (es) 1985-06-06 1986-06-05 Un procedimiento para la preparacion de un compuesto de quinazolinona.
ES557608A Expired ES8801657A1 (es) 1985-06-06 1987-06-26 Un procedimiento para la preparacion de un compuesto de quinazolina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES557608A Expired ES8801657A1 (es) 1985-06-06 1987-06-26 Un procedimiento para la preparacion de un compuesto de quinazolina

Country Status (7)

Country Link
US (1) US4762839A (es)
EP (1) EP0204534B1 (es)
AU (1) AU587641B2 (es)
CA (1) CA1287632C (es)
DE (1) DE3677259D1 (es)
ES (2) ES8801656A1 (es)
MY (1) MY100957A (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT394722B (de) * 1986-08-29 1992-06-10 Tanabe Seiyaku Co Verfahren zur herstellung neuer chinazolinonverbindungen
JPS6360987A (ja) * 1986-08-29 1988-03-17 Tanabe Seiyaku Co Ltd キナゾリノン誘導体の製法
JPS63132889A (ja) * 1986-11-21 1988-06-04 Tanabe Seiyaku Co Ltd キナゾリノン誘導体
US7465738B2 (en) 2003-06-16 2008-12-16 Vertex Pharmaceuticals Incorporated Compounds useful as promoters of SMN2
JP5470043B2 (ja) * 2007-10-05 2014-04-16 Ｍｓｄ株式会社 ベンゾオキサジノン誘導体

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT321911B (de) * 1971-05-27 1975-04-25 Sandoz Ag Verfahren zur herstellung vonneuen 1-alkyl-4-phenyl-bzw.-4-(2-thienyl)6,7-methylendioxy-34-dihydro-2(1h)-chinazolinonen
JPS53653A (en) * 1976-06-23 1978-01-06 Matsushita Refrig Co Air conditioner
US4117230A (en) * 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4282229A (en) * 1977-02-11 1981-08-04 Pfizer Inc. Hydantoin derivatives as therapeutic agents
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4273775A (en) * 1979-06-13 1981-06-16 Pfizer Inc. Hydantoin derivatives, anti-diabetic compositions thereof, and method of use thereof
US4490381A (en) * 1979-11-13 1984-12-25 Imperial Chemical Industries Plc 1'-Substituted spiro[imidazolidine-4,3'-indoline]2,2',5-triones
JPS56104876A (en) * 1980-01-24 1981-08-20 Takeda Chem Ind Ltd Thiazolidine derivative
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
US4464380A (en) * 1983-05-25 1984-08-07 Pfizer Inc. Imidazolidinedione derivatives
US4533667A (en) * 1983-05-25 1985-08-06 Pfizer Inc. Imidazolidinedione derivatives
US4617392A (en) * 1983-09-29 1986-10-14 Ortho Pharmaceutical Corporation 4-alkyl-5,6-methylenedioxy-2-1[H]-quinazolinones useful as cardiotonic agents
US4575507A (en) * 1985-05-29 1986-03-11 Pfizer Inc. Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use

Also Published As

Publication number Publication date
US4762839A (en) 1988-08-09
EP0204534B1 (en) 1991-01-30
AU587641B2 (en) 1989-08-24
ES557608A0 (es) 1988-02-16
ES8801657A1 (es) 1988-02-16
DE3677259D1 (de) 1991-03-07
AU6421886A (en) 1988-04-21
MY100957A (en) 1991-06-15
EP0204534A3 (en) 1988-01-07
CA1287632C (en) 1991-08-13
ES555761A0 (es) 1988-02-16
EP0204534A2 (en) 1986-12-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401