ATE168995T1 - N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen - Google Patents

N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen

Info

Publication number
ATE168995T1
ATE168995T1 AT92921688T AT92921688T ATE168995T1 AT E168995 T1 ATE168995 T1 AT E168995T1 AT 92921688 T AT92921688 T AT 92921688T AT 92921688 T AT92921688 T AT 92921688T AT E168995 T1 ATE168995 T1 AT E168995T1
Authority
AT
Austria
Prior art keywords
radical
aryl
preparation
pharmaceutical compositions
alkyl
Prior art date
Application number
AT92921688T
Other languages
English (en)
Inventor
Marie-Claude Fournie-Zaluski
Bernard Pierre Roques
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Application granted granted Critical
Publication of ATE168995T1 publication Critical patent/ATE168995T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92921688T 1991-10-25 1992-10-21 N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen ATE168995T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9113174A FR2682952B1 (fr) 1991-10-25 1991-10-25 Nouveaux n-(mercaptoacyl) amino-acides, leur preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ATE168995T1 true ATE168995T1 (de) 1998-08-15

Family

ID=9418304

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92921688T ATE168995T1 (de) 1991-10-25 1992-10-21 N-(mercaptoacyl)aminosäure, ihre herstellung, ihre therapeutische verwendung und sie enthaltende pharmazeutische zusammensetzungen

Country Status (11)

Country Link
EP (2) EP0539848A1 (de)
JP (2) JP3250806B2 (de)
AT (1) ATE168995T1 (de)
AU (1) AU666141B2 (de)
CA (1) CA2121801A1 (de)
DE (1) DE69226443T2 (de)
DK (1) DK0609310T3 (de)
ES (1) ES2118833T3 (de)
FR (1) FR2682952B1 (de)
MX (1) MX9206149A (de)
WO (1) WO1993008162A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1273455B (it) * 1995-01-27 1997-07-08 Zambon Spa Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
FR2731219B1 (fr) * 1995-03-03 1997-04-25 Bioprojet Soc Civ Procede de synthese d'acides acryliques alpha-substitues et leur application
IT1277736B1 (it) * 1995-12-28 1997-11-12 Zambon Spa Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
IT1277737B1 (it) * 1995-12-28 1997-11-12 Zambon Spa Derivati tiolici ad attivita' inibitrice delle metallopeptidasi

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0136883B1 (de) * 1983-10-03 1987-11-25 E.R. Squibb & Sons, Inc. Enkephalinase Inhibitoren
FR2617070A2 (fr) * 1987-03-23 1988-12-30 Collet Claude Appareil de prehension, type mandrin, entierement automatique, a commandes d'ouverture et de fermeture ultra-rapides
CA1337400C (en) * 1987-06-08 1995-10-24 Norma G. Delaney Inhibitors of neutral endopeptidase
US4879309A (en) * 1988-09-27 1989-11-07 Schering Corporation Mercapto-acylamino acids as antihypertensives

Also Published As

Publication number Publication date
JPH07509441A (ja) 1995-10-19
EP0609310B1 (de) 1998-07-29
ES2118833T3 (es) 1998-10-01
FR2682952B1 (fr) 1993-12-03
CA2121801A1 (en) 1993-04-29
FR2682952A1 (fr) 1993-04-30
DE69226443D1 (de) 1998-09-03
JP2002030066A (ja) 2002-01-29
WO1993008162A1 (en) 1993-04-29
JP3250806B2 (ja) 2002-01-28
DE69226443T2 (de) 1999-02-04
EP0539848A1 (de) 1993-05-05
AU666141B2 (en) 1996-02-01
DK0609310T3 (da) 1999-04-26
MX9206149A (es) 1993-08-01
AU2789592A (en) 1993-05-21
EP0609310A1 (de) 1994-08-10

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee