DE68917772D1 - 2-Alkyl-3-benzoylbenzofurane und diese enthaltende pharmazeutische Zusammensetzungen. - Google Patents

2-Alkyl-3-benzoylbenzofurane und diese enthaltende pharmazeutische Zusammensetzungen.

Info

Publication number
DE68917772D1
DE68917772D1 DE68917772T DE68917772T DE68917772D1 DE 68917772 D1 DE68917772 D1 DE 68917772D1 DE 68917772 T DE68917772 T DE 68917772T DE 68917772 T DE68917772 T DE 68917772T DE 68917772 D1 DE68917772 D1 DE 68917772D1
Authority
DE
Germany
Prior art keywords
alkyl
benzoylbenzofurans
pharmaceutical compositions
compositions containing
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68917772T
Other languages
English (en)
Other versions
DE68917772T2 (de
Inventor
Barrie Levitt
Morris Stolar
Ron Breiman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taro Pharmaceutical Industries Ltd
Taro Vit Industries Ltd
Original Assignee
Taro Pharmaceutical Industries Ltd
Taro Vit Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taro Pharmaceutical Industries Ltd, Taro Vit Industries Ltd filed Critical Taro Pharmaceutical Industries Ltd
Application granted granted Critical
Publication of DE68917772D1 publication Critical patent/DE68917772D1/de
Publication of DE68917772T2 publication Critical patent/DE68917772T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE68917772T 1988-04-18 1989-04-17 2-Alkyl-3-benzoylbenzofurane und diese enthaltende pharmazeutische Zusammensetzungen. Expired - Fee Related DE68917772T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/182,402 US4831054A (en) 1988-04-18 1988-04-18 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia

Publications (2)

Publication Number Publication Date
DE68917772D1 true DE68917772D1 (de) 1994-10-06
DE68917772T2 DE68917772T2 (de) 1995-03-02

Family

ID=22668313

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68917772T Expired - Fee Related DE68917772T2 (de) 1988-04-18 1989-04-17 2-Alkyl-3-benzoylbenzofurane und diese enthaltende pharmazeutische Zusammensetzungen.

Country Status (12)

Country Link
US (1) US4831054A (de)
EP (1) EP0338746B1 (de)
JP (1) JP2701933B2 (de)
AT (1) ATE110721T1 (de)
AU (1) AU616134B2 (de)
CA (1) CA1296734C (de)
DE (1) DE68917772T2 (de)
DK (1) DK167253B1 (de)
ES (1) ES2063815T3 (de)
IE (1) IE65529B1 (de)
IL (1) IL89908A0 (de)
ZA (1) ZA892695B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
US5234949A (en) * 1992-04-01 1993-08-10 Academic Pharmaceuticals, Inc. Parenteral solutions containing amiodarone in acetate buffer solution
JPH06124078A (ja) * 1992-10-13 1994-05-06 Max Co Ltd 欧文文書処理に於けるカーニング処理方法
DE19547263C2 (de) * 1995-12-07 1999-04-29 Cardiotec Inc Amidinohydrazone vom Benzo[b]furan abgeleiteter Ketone, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
FR2764800B1 (fr) 1997-06-23 1999-09-10 Sanofi Sa Composition pharmaceutique solide contenant des derives de benzofuranne
US6030998A (en) * 1997-06-27 2000-02-29 Academic Pharmaceuticals, Lp Methods for treating arrhythmia using acetate buffer solutions of amiodarone
FR2813306B1 (fr) * 2000-08-23 2005-10-21 Sanofi Synthelabo Aminoalkybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
FR2813307B1 (fr) * 2000-08-23 2002-11-08 Sanofi Synthelabo Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
FR2813308B1 (fr) 2000-08-23 2005-07-01 Sanofi Synthelabo Aminoalkoxybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation ainsi que les compositions les contenant
FR2864536B1 (fr) * 2003-12-24 2006-03-17 Clariant France Sa Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
KR20100135909A (ko) 2008-04-17 2010-12-27 사노피-아벤티스 심혈관성 입원 또는 사망을 예방하는데 사용하기 위한 약제의 제조에 있어서의 드로네다론의 용도
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation
FR2967067A1 (fr) 2010-11-10 2012-05-11 Sanofi Aventis Composition pharmaceutique et forme galenique a base de dronedarone et son procede de preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3012042A (en) * 1956-12-21 1961-12-05 Belge Produits Chimiques Sa Benzofurans
US3331845A (en) * 1963-04-04 1967-07-18 American Cyanamid Co 1-substituted-4-substituted amino alkylene piperazines
GB1521932A (en) * 1976-03-08 1978-08-16 Labaz Sulphonamide derivatives and process for preparing the same
FR2549475B1 (fr) * 1983-07-18 1986-02-07 Labaz Sanofi Nv Nouveaux derives de benzofuranne, leur preparation et leur utilisation therapeutique

Also Published As

Publication number Publication date
AU3309489A (en) 1989-10-19
CA1296734C (en) 1992-03-03
IE65529B1 (en) 1995-11-01
JP2701933B2 (ja) 1998-01-21
JPH0242073A (ja) 1990-02-13
AU616134B2 (en) 1991-10-17
EP0338746A1 (de) 1989-10-25
DE68917772T2 (de) 1995-03-02
DK167253B1 (da) 1993-09-27
ATE110721T1 (de) 1994-09-15
DK183789A (da) 1989-10-19
IL89908A0 (en) 1989-12-15
IE891199L (en) 1989-10-18
ES2063815T3 (es) 1995-01-16
DK183789D0 (da) 1989-04-17
ZA892695B (en) 1989-12-27
EP0338746B1 (de) 1994-08-31
US4831054A (en) 1989-05-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee