ZA892695B - 2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing them - Google Patents

2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing them

Info

Publication number
ZA892695B
ZA892695B ZA892695A ZA892695A ZA892695B ZA 892695 B ZA892695 B ZA 892695B ZA 892695 A ZA892695 A ZA 892695A ZA 892695 A ZA892695 A ZA 892695A ZA 892695 B ZA892695 B ZA 892695B
Authority
ZA
South Africa
Prior art keywords
alkyl
benzoylbenzofurans
pharmaceutical compositions
compositions containing
carbon atoms
Prior art date
Application number
ZA892695A
Other languages
English (en)
Inventor
Barrie Levitt
Levitt Barrie
Morris Stolar
Stolar Morris
Ron Breiman
Breiman Ron
Original Assignee
Taro Pharma Ind
Taro Vit Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taro Pharma Ind, Taro Vit Ind Ltd filed Critical Taro Pharma Ind
Publication of ZA892695B publication Critical patent/ZA892695B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA892695A 1988-04-18 1989-04-13 2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing them ZA892695B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/182,402 US4831054A (en) 1988-04-18 1988-04-18 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia

Publications (1)

Publication Number Publication Date
ZA892695B true ZA892695B (en) 1989-12-27

Family

ID=22668313

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA892695A ZA892695B (en) 1988-04-18 1989-04-13 2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing them

Country Status (12)

Country Link
US (1) US4831054A (de)
EP (1) EP0338746B1 (de)
JP (1) JP2701933B2 (de)
AT (1) ATE110721T1 (de)
AU (1) AU616134B2 (de)
CA (1) CA1296734C (de)
DE (1) DE68917772T2 (de)
DK (1) DK167253B1 (de)
ES (1) ES2063815T3 (de)
IE (1) IE65529B1 (de)
IL (1) IL89908A0 (de)
ZA (1) ZA892695B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
US5234949A (en) * 1992-04-01 1993-08-10 Academic Pharmaceuticals, Inc. Parenteral solutions containing amiodarone in acetate buffer solution
JPH06124078A (ja) * 1992-10-13 1994-05-06 Max Co Ltd 欧文文書処理に於けるカーニング処理方法
DE19547263C2 (de) * 1995-12-07 1999-04-29 Cardiotec Inc Amidinohydrazone vom Benzo[b]furan abgeleiteter Ketone, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
FR2764800B1 (fr) 1997-06-23 1999-09-10 Sanofi Sa Composition pharmaceutique solide contenant des derives de benzofuranne
US6030998A (en) * 1997-06-27 2000-02-29 Academic Pharmaceuticals, Lp Methods for treating arrhythmia using acetate buffer solutions of amiodarone
FR2813307B1 (fr) * 2000-08-23 2002-11-08 Sanofi Synthelabo Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
FR2813308B1 (fr) * 2000-08-23 2005-07-01 Sanofi Synthelabo Aminoalkoxybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation ainsi que les compositions les contenant
FR2813306B1 (fr) * 2000-08-23 2005-10-21 Sanofi Synthelabo Aminoalkybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant
FR2864536B1 (fr) * 2003-12-24 2006-03-17 Clariant France Sa Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
CN102065855A (zh) 2008-04-17 2011-05-18 赛诺菲-安万特 决奈达隆在制备用于预防因心血管疾病住院或死亡的药物中的用途
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation
FR2967067A1 (fr) 2010-11-10 2012-05-11 Sanofi Aventis Composition pharmaceutique et forme galenique a base de dronedarone et son procede de preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3012042A (en) * 1956-12-21 1961-12-05 Belge Produits Chimiques Sa Benzofurans
US3331845A (en) * 1963-04-04 1967-07-18 American Cyanamid Co 1-substituted-4-substituted amino alkylene piperazines
GB1521932A (en) * 1976-03-08 1978-08-16 Labaz Sulphonamide derivatives and process for preparing the same
FR2549475B1 (fr) * 1983-07-18 1986-02-07 Labaz Sanofi Nv Nouveaux derives de benzofuranne, leur preparation et leur utilisation therapeutique

Also Published As

Publication number Publication date
JP2701933B2 (ja) 1998-01-21
AU616134B2 (en) 1991-10-17
IE891199L (en) 1989-10-18
AU3309489A (en) 1989-10-19
CA1296734C (en) 1992-03-03
JPH0242073A (ja) 1990-02-13
EP0338746B1 (de) 1994-08-31
EP0338746A1 (de) 1989-10-25
DK183789D0 (da) 1989-04-17
ATE110721T1 (de) 1994-09-15
DE68917772D1 (de) 1994-10-06
DK183789A (da) 1989-10-19
IL89908A0 (en) 1989-12-15
IE65529B1 (en) 1995-11-01
DE68917772T2 (de) 1995-03-02
US4831054A (en) 1989-05-16
ES2063815T3 (es) 1995-01-16
DK167253B1 (da) 1993-09-27

Similar Documents

Publication Publication Date Title
IL77395A (en) Pharmaceutical compositions containing 1-benzo-fused heterocyclyl)-piperazine derivatives,certain such novel compounds and their preparation
HUT52764A (en) Process for producing pyrimidindione derivatives and pharmaceutical compositions containing them as active components
HUT54357A (en) Process for producing benzilidene-(azolylmethyl)-cycloalkane and -cycloalkene derivatives, fungicidal compositions comprising such compounds as active ingredient and intermediates usable for the production of the active ingredients
CY1955A (en) Immunomodulatory azaspiranes
EP0324387A3 (en) Composition for treatment of ischemic disorder in organs
IL89908A0 (en) 2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing them
PL309874A1 (en) Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
IL86080A0 (en) Bicyclic compounds,processes for preparation thereof and pharmaceutical composition comprising the same
IL90724A0 (en) Novel esters and pharmaceutical compositions containing same
IL85768A (en) Benzoxazine derivatives, their preparation and pharmaceutical compositions containing them
GR3007401T3 (de)
HUT49283A (en) Process for production of medical compositions applicable for treatment of peptical ulcer
IL75987A0 (en) 1,6-naphthyridine derivatives,their preparation and pharmaceutical compositions containing them
GR3007219T3 (de)
DE3681973D1 (de) Dipercarbonsaeuren und bleichmittel.
NZ234450A (en) Substituted pyrrolo(2,1-b)thiazole derivatives, intermediates and pharmaceutical compositions