ZA892695B - 2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing them - Google Patents
2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing themInfo
- Publication number
- ZA892695B ZA892695B ZA892695A ZA892695A ZA892695B ZA 892695 B ZA892695 B ZA 892695B ZA 892695 A ZA892695 A ZA 892695A ZA 892695 A ZA892695 A ZA 892695A ZA 892695 B ZA892695 B ZA 892695B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- benzoylbenzofurans
- pharmaceutical compositions
- compositions containing
- carbon atoms
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000011149 active material Substances 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/182,402 US4831054A (en) | 1988-04-18 | 1988-04-18 | 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA892695B true ZA892695B (en) | 1989-12-27 |
Family
ID=22668313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA892695A ZA892695B (en) | 1988-04-18 | 1989-04-13 | 2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing them |
Country Status (12)
Country | Link |
---|---|
US (1) | US4831054A (de) |
EP (1) | EP0338746B1 (de) |
JP (1) | JP2701933B2 (de) |
AT (1) | ATE110721T1 (de) |
AU (1) | AU616134B2 (de) |
CA (1) | CA1296734C (de) |
DE (1) | DE68917772T2 (de) |
DK (1) | DK167253B1 (de) |
ES (1) | ES2063815T3 (de) |
IE (1) | IE65529B1 (de) |
IL (1) | IL89908A0 (de) |
ZA (1) | ZA892695B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2665444B1 (fr) * | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
US5234949A (en) * | 1992-04-01 | 1993-08-10 | Academic Pharmaceuticals, Inc. | Parenteral solutions containing amiodarone in acetate buffer solution |
JPH06124078A (ja) * | 1992-10-13 | 1994-05-06 | Max Co Ltd | 欧文文書処理に於けるカーニング処理方法 |
DE19547263C2 (de) * | 1995-12-07 | 1999-04-29 | Cardiotec Inc | Amidinohydrazone vom Benzo[b]furan abgeleiteter Ketone, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
FR2764800B1 (fr) | 1997-06-23 | 1999-09-10 | Sanofi Sa | Composition pharmaceutique solide contenant des derives de benzofuranne |
US6030998A (en) * | 1997-06-27 | 2000-02-29 | Academic Pharmaceuticals, Lp | Methods for treating arrhythmia using acetate buffer solutions of amiodarone |
FR2813307B1 (fr) * | 2000-08-23 | 2002-11-08 | Sanofi Synthelabo | Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant |
FR2813308B1 (fr) * | 2000-08-23 | 2005-07-01 | Sanofi Synthelabo | Aminoalkoxybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation ainsi que les compositions les contenant |
FR2813306B1 (fr) * | 2000-08-23 | 2005-10-21 | Sanofi Synthelabo | Aminoalkybenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant |
FR2864536B1 (fr) * | 2003-12-24 | 2006-03-17 | Clariant France Sa | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
CN102065855A (zh) | 2008-04-17 | 2011-05-18 | 赛诺菲-安万特 | 决奈达隆在制备用于预防因心血管疾病住院或死亡的药物中的用途 |
US8602215B2 (en) | 2010-06-30 | 2013-12-10 | Sanofi | Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation |
FR2967067A1 (fr) | 2010-11-10 | 2012-05-11 | Sanofi Aventis | Composition pharmaceutique et forme galenique a base de dronedarone et son procede de preparation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3012042A (en) * | 1956-12-21 | 1961-12-05 | Belge Produits Chimiques Sa | Benzofurans |
US3331845A (en) * | 1963-04-04 | 1967-07-18 | American Cyanamid Co | 1-substituted-4-substituted amino alkylene piperazines |
GB1521932A (en) * | 1976-03-08 | 1978-08-16 | Labaz | Sulphonamide derivatives and process for preparing the same |
FR2549475B1 (fr) * | 1983-07-18 | 1986-02-07 | Labaz Sanofi Nv | Nouveaux derives de benzofuranne, leur preparation et leur utilisation therapeutique |
-
1988
- 1988-04-18 US US07/182,402 patent/US4831054A/en not_active Expired - Lifetime
-
1989
- 1989-04-11 IL IL89908A patent/IL89908A0/xx not_active IP Right Cessation
- 1989-04-13 ZA ZA892695A patent/ZA892695B/xx unknown
- 1989-04-14 IE IE119989A patent/IE65529B1/en not_active IP Right Cessation
- 1989-04-17 DE DE68917772T patent/DE68917772T2/de not_active Expired - Fee Related
- 1989-04-17 AU AU33094/89A patent/AU616134B2/en not_active Ceased
- 1989-04-17 AT AT89303772T patent/ATE110721T1/de not_active IP Right Cessation
- 1989-04-17 EP EP89303772A patent/EP0338746B1/de not_active Expired - Lifetime
- 1989-04-17 DK DK183789A patent/DK167253B1/da not_active IP Right Cessation
- 1989-04-17 ES ES89303772T patent/ES2063815T3/es not_active Expired - Lifetime
- 1989-04-18 CA CA000596999A patent/CA1296734C/en not_active Expired - Lifetime
- 1989-04-18 JP JP1098644A patent/JP2701933B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2701933B2 (ja) | 1998-01-21 |
AU616134B2 (en) | 1991-10-17 |
IE891199L (en) | 1989-10-18 |
AU3309489A (en) | 1989-10-19 |
CA1296734C (en) | 1992-03-03 |
JPH0242073A (ja) | 1990-02-13 |
EP0338746B1 (de) | 1994-08-31 |
EP0338746A1 (de) | 1989-10-25 |
DK183789D0 (da) | 1989-04-17 |
ATE110721T1 (de) | 1994-09-15 |
DE68917772D1 (de) | 1994-10-06 |
DK183789A (da) | 1989-10-19 |
IL89908A0 (en) | 1989-12-15 |
IE65529B1 (en) | 1995-11-01 |
DE68917772T2 (de) | 1995-03-02 |
US4831054A (en) | 1989-05-16 |
ES2063815T3 (es) | 1995-01-16 |
DK167253B1 (da) | 1993-09-27 |
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