ATE232528T1 - Pyrimidinylpyrazolderivate - Google Patents

Pyrimidinylpyrazolderivate

Info

Publication number
ATE232528T1
ATE232528T1 AT95932229T AT95932229T ATE232528T1 AT E232528 T1 ATE232528 T1 AT E232528T1 AT 95932229 T AT95932229 T AT 95932229T AT 95932229 T AT95932229 T AT 95932229T AT E232528 T1 ATE232528 T1 AT E232528T1
Authority
AT
Austria
Prior art keywords
group
hydrogen atom
chem
formula
pyrimidinylpyrazole
Prior art date
Application number
AT95932229T
Other languages
English (en)
Inventor
Akio Ejima
Masamichi Sugimori
Ikuo Mitsui
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE232528T1 publication Critical patent/ATE232528T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT95932229T 1994-09-26 1995-09-25 Pyrimidinylpyrazolderivate ATE232528T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22942294 1994-09-26
JP13501095 1995-06-01
PCT/JP1995/001934 WO1996010024A1 (en) 1994-09-26 1995-09-25 Pyrimidinylpyrazole derivative

Publications (1)

Publication Number Publication Date
ATE232528T1 true ATE232528T1 (de) 2003-02-15

Family

ID=26468965

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95932229T ATE232528T1 (de) 1994-09-26 1995-09-25 Pyrimidinylpyrazolderivate

Country Status (14)

Country Link
US (1) US5852019A (de)
EP (1) EP0784055B1 (de)
KR (1) KR100388568B1 (de)
CN (1) CN1071754C (de)
AT (1) ATE232528T1 (de)
CA (1) CA2201110A1 (de)
DE (2) DE69529619T4 (de)
DK (1) DK0784055T3 (de)
ES (1) ES2192584T3 (de)
FI (1) FI971227A (de)
HK (1) HK1001396A1 (de)
NO (1) NO313196B1 (de)
TW (1) TW312694B (de)
WO (1) WO1996010024A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6169086B1 (en) 1997-01-27 2001-01-02 Daiichi Pharmaceutical Co., Ltd. Pyrazole derivatives
CN1105707C (zh) * 1997-01-27 2003-04-16 第一制药株式会社 吡唑衍生物
AU4800299A (en) * 1998-07-24 2000-02-14 Daiichi Pharmaceutical Co., Ltd. Pyrazole derivatives and salts thereof
JP4709388B2 (ja) * 1999-01-25 2011-06-22 全薬工業株式会社 複素環式化合物及びそれを有効成分とする抗腫瘍剤
ES2280530T3 (es) * 2001-04-27 2007-09-16 Zenyaku Kogyo Kabushiki Kaisha Compuesto heterociclico y agente antitumoral que contiene el mismo como principio activo.
WO2003011837A1 (en) * 2001-08-01 2003-02-13 Merck & Co., Inc. Tyrosine kinase inhibitors
JP2006516656A (ja) * 2003-01-28 2006-07-06 アヴェンティス ファーマ エス．エー． Ｎ−アリールヘテロ芳香族物質、それを含む組成物およびその用途
FR2850379B1 (fr) * 2003-01-28 2006-11-17 Aventis Pharma Sa Produits n-aryl-heteroaromatiques, compositions les contenant et utilisation
US20050130989A1 (en) * 2003-01-28 2005-06-16 Aventis Pharma S. A. N-arylheteroaromatic products compositions containing them and use thereof
US7223759B2 (en) * 2003-09-15 2007-05-29 Anadys Pharmaceuticals, Inc. Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds
CN100532380C (zh) 2004-03-31 2009-08-26 全药工业株式会社 杂环化合物和以其作为有效成分的抗恶性肿瘤药
PT1864665E (pt) * 2005-03-11 2012-06-27 Zenyaku Kogyo Kk Agente imunossupressor compreendendo um composto heterocíclico como ingrediente activo
US20070244110A1 (en) * 2006-04-14 2007-10-18 Zenyaku Kogyo Kabushiki Kaisha Treatment of prostate cancer, melanoma or hepatic cancer
CA2675511A1 (en) 2006-10-10 2008-04-17 Amgen Inc. N-aryl pyrazole compounds for use against diabetes
EP3285581B1 (de) * 2015-03-26 2021-08-11 Merck Sharp & Dohme Corp. Pyrazolylpyrimidinonverbindungen als pde2-inhibitoren
WO2017059191A1 (en) 2015-09-30 2017-04-06 Quartet Medicine, Inc. Heteroaryl derivatives as sepiapterin reductase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3778433A (en) * 1969-04-18 1973-12-11 Sumitomo Chemical Co Process for producing benzodiazepine derivatives
JPS4842072A (de) * 1971-09-29 1973-06-19
JPS61129129A (ja) * 1984-11-28 1986-06-17 Kureha Chem Ind Co Ltd 抗腫瘍剤
US5102893A (en) * 1986-07-07 1992-04-07 Warner-Lambert Company Trans-6-(2-(n-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl- or ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis

Also Published As

Publication number Publication date
WO1996010024A1 (en) 1996-04-04
DE69529619T2 (de) 2003-12-18
HK1001396A1 (en) 1998-06-19
CA2201110A1 (en) 1996-04-04
DK0784055T3 (da) 2003-06-02
EP0784055A4 (de) 1998-01-07
EP0784055A1 (de) 1997-07-16
US5852019A (en) 1998-12-22
NO971384L (no) 1997-05-23
KR100388568B1 (ko) 2003-10-04
CN1071754C (zh) 2001-09-26
NO971384D0 (no) 1997-03-24
CN1166833A (zh) 1997-12-03
TW312694B (de) 1997-08-11
FI971227A (fi) 1997-05-23
ES2192584T3 (es) 2003-10-16
KR970706275A (ko) 1997-11-03
EP0784055B1 (de) 2003-02-12
DE69529619D1 (en) 2003-03-20
FI971227A0 (fi) 1997-03-24
NO313196B1 (no) 2002-08-26
DE69529619T4 (de) 2005-01-27

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