ATE248814T1 - 16-ene-vitamin d derivate - Google Patents

16-ene-vitamin d derivate

Info

Publication number
ATE248814T1
ATE248814T1 AT97949173T AT97949173T ATE248814T1 AT E248814 T1 ATE248814 T1 AT E248814T1 AT 97949173 T AT97949173 T AT 97949173T AT 97949173 T AT97949173 T AT 97949173T AT E248814 T1 ATE248814 T1 AT E248814T1
Authority
AT
Austria
Prior art keywords
vitamin
group
hydroxyl group
ene
derivatives
Prior art date
Application number
AT97949173T
Other languages
English (en)
Inventor
A Chugai Kawase
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE248814T1 publication Critical patent/ATE248814T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97949173T 1996-12-20 1997-12-19 16-ene-vitamin d derivate ATE248814T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP34178696 1996-12-20
PCT/JP1997/004715 WO1998028266A1 (fr) 1996-12-20 1997-12-19 Derives de vitamine d 16-ene

Publications (1)

Publication Number Publication Date
ATE248814T1 true ATE248814T1 (de) 2003-09-15

Family

ID=18348753

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97949173T ATE248814T1 (de) 1996-12-20 1997-12-19 16-ene-vitamin d derivate

Country Status (13)

Country Link
US (3) US6326503B1 (de)
EP (1) EP0947504B1 (de)
KR (2) KR20050123185A (de)
AT (1) ATE248814T1 (de)
AU (1) AU720454B2 (de)
CA (1) CA2275382A1 (de)
DE (1) DE69724646T2 (de)
DK (1) DK0947504T3 (de)
ES (1) ES2206758T3 (de)
IL (2) IL130484A (de)
NO (1) NO992981L (de)
PT (1) PT947504E (de)
WO (1) WO1998028266A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998051663A2 (en) * 1997-05-16 1998-11-19 F. Hoffmann-La Roche Ag 3-epi compounds of vitamin d3 and uses thereof
KR20010093339A (ko) * 1999-02-18 2001-10-27 나가야마 오사무 비타민 ｄ 수용체에 친화성을 갖는 화합물의 스크리닝법
US6960576B2 (en) 1999-09-13 2005-11-01 Bristol-Myers Squibb Pharma Company Hydroxyalkanoylaminolactams and related structures as inhibitors of Aβ protein production
AU2001248777A1 (en) * 2000-04-19 2001-10-30 Chugai Seiyaku Kabushiki Kaisha Vitamin d derivatives
TWI288131B (en) * 2000-06-15 2007-10-11 Chugai Pharmaceutical Co Ltd Vitamin D derivative, compounds pharmaceutical composition thereof
CN101462994B (zh) * 2000-06-15 2012-11-28 中外制药株式会社 维生素d衍生物
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
WO2006093291A1 (ja) * 2005-03-04 2006-09-08 Tokyo Medical And Dental University １９－ノルビタミンｄ誘導体
WO2007063930A1 (ja) 2005-11-30 2007-06-07 Chugai Seiyaku Kabushiki Kaisha 光反応を用いるビタミンｄ誘導体の製法
KR20150036717A (ko) 2006-06-02 2015-04-07 니뽄 신야쿠 가부시키가이샤 9,10-세코프레그난 유도체 및 의약
AU2010208323B2 (en) 2009-01-27 2016-03-10 Berg Llc Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (de) 2009-08-14 2019-05-22 Berg LLC Vitamin d3 und analoge davon zur behandlung von alopezie
US9290447B2 (en) 2011-05-03 2016-03-22 Wisconsin Alumni Research Foundation (20R) and (20S)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin D3 analogs and their uses
KR20160013201A (ko) 2013-05-29 2016-02-03 버그 엘엘씨 비타민 d를 이용한 화학요법 유발 탈모증의 예방 또는 완화
CN106279239B (zh) * 2015-05-29 2019-06-28 上海彩迩文生化科技有限公司 多烯化合物、制备方法及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
JPH0680626A (ja) * 1991-05-09 1994-03-22 Chugai Pharmaceut Co Ltd 新規な２２−オキサビタミンｄ誘導体
GB9226877D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Chemical compounds
JP3415877B2 (ja) * 1993-03-05 2003-06-09 中外製薬株式会社 ２２−オキサビタミンｄ誘導体
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US6121469A (en) * 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
WO1995027697A1 (fr) * 1994-04-11 1995-10-19 Chugai Seiyaku Kabushiki Kaisha Derive de la 22-thiavitamine d¿3?
JP3759639B2 (ja) * 1994-04-11 2006-03-29 中外製薬株式会社 ２２−チアビタミン▲ｄ３▼誘導体
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
JP3715673B2 (ja) * 1995-03-10 2005-11-09 中外製薬株式会社 ビタミンｄ合成中間体の製造方法
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs

Also Published As

Publication number Publication date
DE69724646T2 (de) 2004-06-17
US20020193616A1 (en) 2002-12-19
DE69724646D1 (de) 2003-10-09
PT947504E (pt) 2003-12-31
ES2206758T3 (es) 2004-05-16
KR20050123185A (ko) 2005-12-29
US20020032340A1 (en) 2002-03-14
CA2275382A1 (en) 1998-07-02
EP0947504A4 (de) 1999-11-17
KR100573234B1 (ko) 2006-04-24
DK0947504T3 (da) 2003-11-24
NO992981L (no) 1999-08-18
IL130484A (en) 2004-07-25
US6326503B1 (en) 2001-12-04
AU720454B2 (en) 2000-06-01
IL161890A0 (en) 2005-11-20
AU7872798A (en) 1998-07-17
US6555699B2 (en) 2003-04-29
WO1998028266A1 (fr) 1998-07-02
US6433200B1 (en) 2002-08-13
IL130484A0 (en) 2000-06-01
EP0947504B1 (de) 2003-09-03
EP0947504A1 (de) 1999-10-06
NO992981D0 (no) 1999-06-17
KR20000057692A (ko) 2000-09-25

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