DK0947504T3 - 16-en-vitamin D-derivater - Google Patents

16-en-vitamin D-derivater

Info

Publication number
DK0947504T3
DK0947504T3 DK97949173T DK97949173T DK0947504T3 DK 0947504 T3 DK0947504 T3 DK 0947504T3 DK 97949173 T DK97949173 T DK 97949173T DK 97949173 T DK97949173 T DK 97949173T DK 0947504 T3 DK0947504 T3 DK 0947504T3
Authority
DK
Denmark
Prior art keywords
group
vitamin
hydroxyl group
hydrogen atom
derivatives
Prior art date
Application number
DK97949173T
Other languages
English (en)
Inventor
A Chugai Kawase
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DK0947504T3 publication Critical patent/DK0947504T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK97949173T 1996-12-20 1997-12-19 16-en-vitamin D-derivater DK0947504T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP34178696 1996-12-20
PCT/JP1997/004715 WO1998028266A1 (fr) 1996-12-20 1997-12-19 Derives de vitamine d 16-ene

Publications (1)

Publication Number Publication Date
DK0947504T3 true DK0947504T3 (da) 2003-11-24

Family

ID=18348753

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97949173T DK0947504T3 (da) 1996-12-20 1997-12-19 16-en-vitamin D-derivater

Country Status (13)

Country Link
US (3) US6326503B1 (da)
EP (1) EP0947504B1 (da)
KR (2) KR20050123185A (da)
AT (1) ATE248814T1 (da)
AU (1) AU720454B2 (da)
CA (1) CA2275382A1 (da)
DE (1) DE69724646T2 (da)
DK (1) DK0947504T3 (da)
ES (1) ES2206758T3 (da)
IL (2) IL161890A0 (da)
NO (1) NO992981L (da)
PT (1) PT947504E (da)
WO (1) WO1998028266A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7497798A (en) * 1997-05-16 1998-12-08 F. Hoffmann-La Roche Ag 3-epi compounds of vitamin d3 and uses thereof
WO2000049403A1 (fr) * 1999-02-18 2000-08-24 Chugai Seiyaku Kabushiki Kaisha Procede permettant l'identification d'un composant presentant une affinite pour le recepteur de la vitamine d
US6960576B2 (en) 1999-09-13 2005-11-01 Bristol-Myers Squibb Pharma Company Hydroxyalkanoylaminolactams and related structures as inhibitors of Aβ protein production
EP1275643A4 (en) * 2000-04-19 2009-06-03 Chugai Pharmaceutical Co Ltd DERIVATIVES OF VITAMIN D
CN101462994B (zh) * 2000-06-15 2012-11-28 中外制药株式会社 维生素d衍生物
DK1295871T3 (da) * 2000-06-15 2011-07-11 Chugai Pharmaceutical Co Ltd Vitamin D-derivater med et 22-oxa- eller 22-thiaatom, en C17-sidekæde substitueret med en syre-, ester- eller amid-gruppe og en 16(17)-dobbeltbinding
AU2005303773A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin D derivatives and anti-proliferative agents for treating bladder cancer
WO2006093291A1 (ja) * 2005-03-04 2006-09-08 Tokyo Medical And Dental University １９－ノルビタミンｄ誘導体
JP5095413B2 (ja) 2005-11-30 2012-12-12 中外製薬株式会社 光反応を用いるビタミンｄ誘導体の製法
EP2025667B1 (en) 2006-06-02 2016-08-10 Nippon Shinyaku Co., Ltd. 9,10-secopregnane derivative and pharmaceutical
KR101991692B1 (ko) 2009-01-27 2019-06-21 베르그 엘엘씨 화학요법과 연관된 부작용을 경감시키기 위한 비타민 ｄ３ 및 이의 유사물
EA201270226A1 (ru) 2009-08-14 2012-09-28 БЕРГ БАЙОСИСТЕМЗ, ЭлЭлСи Витамин d3 и его аналогии для лечения алопеции
US9290447B2 (en) 2011-05-03 2016-03-22 Wisconsin Alumni Research Foundation (20R) and (20S)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin D3 analogs and their uses
EP3003497B1 (en) 2013-05-29 2024-02-14 BPGbio, Inc. Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN106279239B (zh) * 2015-05-29 2019-06-28 上海彩迩文生化科技有限公司 多烯化合物、制备方法及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
JPH0680626A (ja) * 1991-05-09 1994-03-22 Chugai Pharmaceut Co Ltd 新規な２２−オキサビタミンｄ誘導体
GB9226877D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Chemical compounds
JP3415877B2 (ja) * 1993-03-05 2003-06-09 中外製薬株式会社 ２２−オキサビタミンｄ誘導体
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US6121469A (en) * 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
JP3759639B2 (ja) * 1994-04-11 2006-03-29 中外製薬株式会社 ２２−チアビタミン▲ｄ３▼誘導体
ATE195513T1 (de) * 1994-04-11 2000-09-15 Chugai Pharmaceutical Co Ltd 22-thiavitamin-d3-derivate
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
JP3715673B2 (ja) * 1995-03-10 2005-11-09 中外製薬株式会社 ビタミンｄ合成中間体の製造方法
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs

Also Published As

Publication number Publication date
DE69724646D1 (de) 2003-10-09
PT947504E (pt) 2003-12-31
WO1998028266A1 (fr) 1998-07-02
AU7872798A (en) 1998-07-17
ATE248814T1 (de) 2003-09-15
US6433200B1 (en) 2002-08-13
IL130484A (en) 2004-07-25
NO992981L (no) 1999-08-18
KR20050123185A (ko) 2005-12-29
KR20000057692A (ko) 2000-09-25
US20020193616A1 (en) 2002-12-19
ES2206758T3 (es) 2004-05-16
IL161890A0 (en) 2005-11-20
DE69724646T2 (de) 2004-06-17
US6555699B2 (en) 2003-04-29
IL130484A0 (en) 2000-06-01
EP0947504A1 (en) 1999-10-06
KR100573234B1 (ko) 2006-04-24
EP0947504A4 (da) 1999-11-17
US20020032340A1 (en) 2002-03-14
US6326503B1 (en) 2001-12-04
NO992981D0 (no) 1999-06-17
EP0947504B1 (en) 2003-09-03
CA2275382A1 (en) 1998-07-02
AU720454B2 (en) 2000-06-01

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