NO992981L - 16-en-vitamin D derivater - Google Patents

16-en-vitamin D derivater

Info

Publication number
NO992981L
NO992981L NO992981A NO992981A NO992981L NO 992981 L NO992981 L NO 992981L NO 992981 A NO992981 A NO 992981A NO 992981 A NO992981 A NO 992981A NO 992981 L NO992981 L NO 992981L
Authority
NO
Norway
Prior art keywords
group
vitamin
hydroxyl group
hydrogen atom
derivatives
Prior art date
Application number
NO992981A
Other languages
English (en)
Other versions
NO992981D0 (no
Inventor
Akira Kawase
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of NO992981D0 publication Critical patent/NO992981D0/no
Publication of NO992981L publication Critical patent/NO992981L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Vitamin D derivater med generell formel (1) hvor X representerer oksygen eller svovel, Rrepresenterer mettet eller umettet alifatisk hydrokarbyl som kan være substituert med hydroksyl eller beskyttet hydroksyl, eller -COR(hvor Rrepresenterer alkyl, aryl eller alkoksyl), Rrepresenterer -0Reller hydrogen, og Rog Rhver representerer hydrogen eller hydroksyl, en fremgangsmåte for fremstilling av disse, mellomprodukter for disse, og medisiner som erå inneholde disse.
NO992981A 1996-12-20 1999-06-17 16-en-vitamin D derivater NO992981L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP34178696 1996-12-20
PCT/JP1997/004715 WO1998028266A1 (fr) 1996-12-20 1997-12-19 Derives de vitamine d 16-ene

Publications (2)

Publication Number Publication Date
NO992981D0 NO992981D0 (no) 1999-06-17
NO992981L true NO992981L (no) 1999-08-18

Family

ID=18348753

Family Applications (1)

Application Number Title Priority Date Filing Date
NO992981A NO992981L (no) 1996-12-20 1999-06-17 16-en-vitamin D derivater

Country Status (13)

Country Link
US (3) US6326503B1 (no)
EP (1) EP0947504B1 (no)
KR (2) KR20050123185A (no)
AT (1) ATE248814T1 (no)
AU (1) AU720454B2 (no)
CA (1) CA2275382A1 (no)
DE (1) DE69724646T2 (no)
DK (1) DK0947504T3 (no)
ES (1) ES2206758T3 (no)
IL (2) IL161890A0 (no)
NO (1) NO992981L (no)
PT (1) PT947504E (no)
WO (1) WO1998028266A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010007907A1 (en) * 1997-05-16 2001-07-12 Women And Infants Hospital 3-epi compounds of vitamin d3 and uses thereof
CN1341213A (zh) * 1999-02-18 2002-03-20 中外制药株式会社 筛选具有维生素d受体亲和性的化合物的方法
US6960576B2 (en) 1999-09-13 2005-11-01 Bristol-Myers Squibb Pharma Company Hydroxyalkanoylaminolactams and related structures as inhibitors of Aβ protein production
EP1275643A4 (en) 2000-04-19 2009-06-03 Chugai Pharmaceutical Co Ltd DERIVATIVES OF VITAMIN D
KR100786053B1 (ko) 2000-06-15 2007-12-17 쥬가이 세이야쿠 가부시키가이샤 비타민 ｄ 유도체
ES2364623T3 (es) * 2000-06-15 2011-09-08 Chugai Seiyaku Kabushiki Kaisha Derivados de vitamina d que poseen un átomo 22-oxa o 22-tia, una cadena lateral c17 sustituida con un grupo ácido, éster o amida y un enlace doble 16(17).
EP1812011A1 (en) 2004-11-12 2007-08-01 Bioxell S.p.a. Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
WO2006093291A1 (ja) * 2005-03-04 2006-09-08 Tokyo Medical And Dental University １９－ノルビタミンｄ誘導体
DK1961740T3 (da) * 2005-11-30 2013-05-27 Chugai Pharmaceutical Co Ltd Fremgangsmåde til at fremstille vitamin D derivate ved at udnytte fotoreaktion
KR20160112018A (ko) 2006-06-02 2016-09-27 니뽄 신야쿠 가부시키가이샤 9,10-세코프레그난 유도체 및 의약
EP2393494A1 (en) 2009-01-27 2011-12-14 Berg Biosystems, LLC Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
CA2770683C (en) 2009-08-14 2018-09-04 Berg Biosystems, Llc Vitamin d3 and analogs thereof for treating alopecia
US9290447B2 (en) 2011-05-03 2016-03-22 Wisconsin Alumni Research Foundation (20R) and (20S)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin D3 analogs and their uses
SG10201709894RA (en) 2013-05-29 2018-01-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN106279239B (zh) * 2015-05-29 2019-06-28 上海彩迩文生化科技有限公司 多烯化合物、制备方法及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
JPH0680626A (ja) * 1991-05-09 1994-03-22 Chugai Pharmaceut Co Ltd 新規な２２−オキサビタミンｄ誘導体
GB9226877D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Chemical compounds
JP3415877B2 (ja) * 1993-03-05 2003-06-09 中外製薬株式会社 ２２−オキサビタミンｄ誘導体
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US6121469A (en) * 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
ATE195513T1 (de) * 1994-04-11 2000-09-15 Chugai Pharmaceutical Co Ltd 22-thiavitamin-d3-derivate
JP3759639B2 (ja) * 1994-04-11 2006-03-29 中外製薬株式会社 ２２−チアビタミン▲ｄ３▼誘導体
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
JP3715673B2 (ja) * 1995-03-10 2005-11-09 中外製薬株式会社 ビタミンｄ合成中間体の製造方法
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs

Also Published As

Publication number Publication date
KR20000057692A (ko) 2000-09-25
ATE248814T1 (de) 2003-09-15
AU7872798A (en) 1998-07-17
EP0947504A1 (en) 1999-10-06
NO992981D0 (no) 1999-06-17
WO1998028266A1 (fr) 1998-07-02
EP0947504B1 (en) 2003-09-03
ES2206758T3 (es) 2004-05-16
US6433200B1 (en) 2002-08-13
KR20050123185A (ko) 2005-12-29
US20020193616A1 (en) 2002-12-19
AU720454B2 (en) 2000-06-01
US6555699B2 (en) 2003-04-29
US6326503B1 (en) 2001-12-04
IL161890A0 (en) 2005-11-20
DE69724646T2 (de) 2004-06-17
PT947504E (pt) 2003-12-31
DE69724646D1 (de) 2003-10-09
DK0947504T3 (da) 2003-11-24
IL130484A0 (en) 2000-06-01
EP0947504A4 (no) 1999-11-17
CA2275382A1 (en) 1998-07-02
IL130484A (en) 2004-07-25
KR100573234B1 (ko) 2006-04-24
US20020032340A1 (en) 2002-03-14

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application