FI880281A - Foerfarande foer framstaellning av b-avermektiner och deras kulturer. - Google Patents
Foerfarande foer framstaellning av b-avermektiner och deras kulturer. Download PDFInfo
- Publication number
- FI880281A FI880281A FI880281A FI880281A FI880281A FI 880281 A FI880281 A FI 880281A FI 880281 A FI880281 A FI 880281A FI 880281 A FI880281 A FI 880281A FI 880281 A FI880281 A FI 880281A
- Authority
- FI
- Finland
- Prior art keywords
- kulturer
- avermektiner
- foerfarande foer
- foer framstaellning
- och deras
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US651287A | 1987-01-23 | 1987-01-23 | |
US651287 | 2000-08-30 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI880281A0 FI880281A0 (fi) | 1988-01-22 |
FI880281A true FI880281A (fi) | 1988-07-24 |
FI90088B FI90088B (fi) | 1993-09-15 |
FI90088C FI90088C (fi) | 1993-12-27 |
Family
ID=21721247
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI880280A FI90091C (fi) | 1987-01-23 | 1988-01-22 | Foerfarande foer producering av icke-naturliga demetylavermektiner |
FI880281A FI90088C (fi) | 1987-01-23 | 1988-01-22 | Foerfarande foer framstaellning av b-avermektiner och vid foerfarandet anvaendbar odling |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI880280A FI90091C (fi) | 1987-01-23 | 1988-01-22 | Foerfarande foer producering av icke-naturliga demetylavermektiner |
Country Status (30)
Country | Link |
---|---|
EP (2) | EP0276103B1 (fi) |
JP (2) | JPH0681757B2 (fi) |
KR (2) | KR900004419B1 (fi) |
CN (1) | CN1056883C (fi) |
AR (1) | AR241798A1 (fi) |
AT (2) | ATE96174T1 (fi) |
AU (2) | AU595673B2 (fi) |
BG (1) | BG51051A3 (fi) |
BR (1) | BR8800271A (fi) |
CZ (1) | CZ279782B6 (fi) |
DD (2) | DD267512A5 (fi) |
DE (2) | DE3884973T2 (fi) |
DK (2) | DK175720B1 (fi) |
EG (1) | EG18797A (fi) |
ES (2) | ES2059498T3 (fi) |
FI (2) | FI90091C (fi) |
GR (1) | GR3007586T3 (fi) |
HU (2) | HU200487B (fi) |
IE (2) | IE61483B1 (fi) |
IL (2) | IL85118A (fi) |
IN (1) | IN167980B (fi) |
MA (1) | MA21160A1 (fi) |
MY (1) | MY103514A (fi) |
NZ (2) | NZ223271A (fi) |
PL (2) | PL156764B1 (fi) |
PT (2) | PT86583B (fi) |
RU (1) | RU1806198C (fi) |
SK (1) | SK40788A3 (fi) |
YU (1) | YU47878B (fi) |
ZA (3) | ZA88447B (fi) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4806527A (en) * | 1987-03-16 | 1989-02-21 | Merck & Co., Inc. | Avermectin derivatives |
US4874749A (en) * | 1987-07-31 | 1989-10-17 | Merck & Co., Inc. | 4"-Deoxy-4-N-methylamino avermectin Bla/Blb |
EP0313297B1 (en) * | 1987-10-23 | 1993-05-19 | Pfizer Inc. | Process for production of avermectin aglycones and cultures therefor |
GB8807280D0 (en) * | 1988-03-26 | 1988-04-27 | Pfizer Ltd | Antiparasitic agents |
GB8811036D0 (en) * | 1988-05-10 | 1988-06-15 | Glaxo Group Ltd | Chemical compounds |
GB8813760D0 (en) * | 1988-06-10 | 1988-07-13 | American Cyanamid Co | Chemical process |
GB8815967D0 (en) * | 1988-07-05 | 1988-08-10 | Pfizer Ltd | Antiparasitic agents |
NZ231773A (en) * | 1988-12-23 | 1992-09-25 | Merck & Co Inc | Avermectin derivatives, preparation and parasiticidal pharmaceutical compositions thereof |
NZ231772A (en) * | 1988-12-23 | 1992-11-25 | Merck & Co Inc | Avermectin derivatives, preparation and parasiticidal compositions thereof |
US5015630A (en) * | 1989-01-19 | 1991-05-14 | Merck & Co., Inc. | 5-oxime avermectin derivatives |
US4897383A (en) * | 1989-02-13 | 1990-01-30 | Merck & Co., Inc. | Avermectin derivatives |
US5252474A (en) * | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
US5030622A (en) * | 1989-06-02 | 1991-07-09 | Merck & Co., Inc. | Avermectin derivatives |
US5057499A (en) * | 1989-06-02 | 1991-10-15 | Merck & Co. Inc. | Avermectin derivatives |
US5023241A (en) * | 1989-07-31 | 1991-06-11 | Merck & Co., Inc. | Avermectin derivatives |
US5830875A (en) * | 1989-10-30 | 1998-11-03 | Merck & Co., Inc. | 24-and 25-substituted avermectin and milbemycin derivatives |
JP2888586B2 (ja) * | 1990-03-05 | 1999-05-10 | 社団法人北里研究所 | エバーメクチンの特定成分を選択生産するための微生物およびその選択的製造法 |
US5169839A (en) * | 1990-05-11 | 1992-12-08 | Merck & Co., Inc. | Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections |
US5208222A (en) * | 1991-03-28 | 1993-05-04 | Merck & Co., Inc. | 4"-and 4'-alkylthio avermectin derivatives |
US5240915A (en) * | 1991-10-15 | 1993-08-31 | Merck & Co., Inc. | Avermectin derivatives |
US6103504A (en) * | 1992-03-25 | 2000-08-15 | Pfizer Inc. | Process for production of avermectins and cultures therefor |
US5292647A (en) * | 1992-11-30 | 1994-03-08 | Eli Lilly And Company | Strain of streptomyces for producing avermectins and processes therewith |
CN1038330C (zh) * | 1993-07-05 | 1998-05-13 | 塞泰克斯公司 | 阿弗麦菌素的生产与分离 |
KR100221385B1 (ko) * | 1993-07-30 | 1999-10-01 | 디. 제이. 우드 | 스트렙토마이세스 아베르미틸리스로 부터의 측쇄 알파-케토산 데하이드로게나제 복합체를 암호화하는 유전자 |
SI9420059A (en) * | 1993-10-05 | 1997-02-28 | Pfizer | Process and antiparasitic intermediates for doramectin |
FI942725A (fi) * | 1993-12-16 | 1995-06-17 | Pfizer | Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta |
US5701591A (en) * | 1995-04-07 | 1997-12-23 | Telecommunications Equipment Corporation | Multi-function interactive communications system with circularly/elliptically polarized signal transmission and reception |
PL194270B1 (pl) * | 1998-02-13 | 2007-05-31 | Pfizer Prod Inc | Wyizolowana cząsteczka polinukleotydowa, cząsteczka oligonukleotydowa, zrekombinowany wektor, komórka gospodarza, wyizolowany produkt genu AveC S. avermitilis, wyizolowany produkt homologu genu AveC S. hygroscopicus, sposób wytwarzania zrekombinowanego produktu genu AveC, sposób wytwarzania zrekombinowanego produktu homologu genu AveC, cząsteczka polinukleotydowa, wektor do zastępowania genu, sposób identyfikowania mutacji otwartej ramki odczytuAveC, sposób wytwarzania nowych szczepów S. avermitilis, szczep S. avermitilis i sposób wytwarzaniaawermektyn |
CN1186446C (zh) * | 1999-08-12 | 2005-01-26 | 辉瑞产品公司 | 介导除虫菌素b2:b1比例的除虫链霉茵基因 |
KR100415395B1 (ko) * | 2000-08-02 | 2004-01-16 | 한국생명공학연구원 | 에버멕틴 bc-5-o-메칠트랜스퍼라제의 유전자가 파괴된 스트렙토마이세스 에버미티리스 변이균주 및 그의 제조 방법 |
KR100718378B1 (ko) | 2002-02-12 | 2007-05-14 | 화이자 프로덕츠 인코포레이티드 | B2:b1 아베르멕틴의 비를 제어하는 스트렙토마이세스아베르미틸리스 유전자 |
WO2023203038A1 (en) | 2022-04-19 | 2023-10-26 | Syngenta Crop Protection Ag | Insect, acarina and nematode pest control |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE434277B (sv) | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
NZ188459A (en) * | 1977-10-03 | 1982-09-07 | Merck & Co Inc | Derivatives of c-076 compounds and pesticidal compositions |
US4429042A (en) | 1978-09-08 | 1984-01-31 | Merck & Co., Inc. | Strain of Streptomyces for producing antiparasitic compounds |
ES8800986A1 (es) * | 1985-07-27 | 1987-12-01 | Pfizer | Un procedimiento para la produccion de un nuevo derivado de avermectina |
GB8606120D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Process |
-
1987
- 1987-12-10 IN IN1059/DEL/87A patent/IN167980B/en unknown
-
1988
- 1988-01-18 IL IL85118A patent/IL85118A/xx not_active IP Right Cessation
- 1988-01-18 DE DE88300354T patent/DE3884973T2/de not_active Expired - Lifetime
- 1988-01-18 ES ES88300354T patent/ES2059498T3/es not_active Expired - Lifetime
- 1988-01-18 BG BG82657A patent/BG51051A3/xx unknown
- 1988-01-18 EP EP88300354A patent/EP0276103B1/en not_active Expired - Lifetime
- 1988-01-18 AT AT88300354T patent/ATE96174T1/de not_active IP Right Cessation
- 1988-01-19 MY MYPI88000037A patent/MY103514A/en unknown
- 1988-01-19 MA MA21397A patent/MA21160A1/fr unknown
- 1988-01-20 DE DE8888300426T patent/DE3879975T2/de not_active Expired - Lifetime
- 1988-01-20 AT AT88300426T patent/ATE87927T1/de not_active IP Right Cessation
- 1988-01-20 EP EP88300426A patent/EP0276131B1/en not_active Expired - Lifetime
- 1988-01-20 ES ES88300426T patent/ES2053719T3/es not_active Expired - Lifetime
- 1988-01-21 EG EG3588A patent/EG18797A/xx active
- 1988-01-21 CZ CS88407A patent/CZ279782B6/cs unknown
- 1988-01-21 PL PL1988270239A patent/PL156764B1/pl unknown
- 1988-01-21 PT PT86583A patent/PT86583B/pt unknown
- 1988-01-21 PT PT86584A patent/PT86584B/pt unknown
- 1988-01-21 SK SK407-88A patent/SK40788A3/sk unknown
- 1988-01-21 IL IL85165A patent/IL85165A/xx not_active IP Right Cessation
- 1988-01-21 PL PL1988270238A patent/PL156763B1/pl unknown
- 1988-01-22 AU AU10696/88A patent/AU595673B2/en not_active Expired
- 1988-01-22 NZ NZ223271A patent/NZ223271A/en unknown
- 1988-01-22 NZ NZ223272A patent/NZ223272A/xx unknown
- 1988-01-22 IE IE16088A patent/IE61483B1/en not_active IP Right Cessation
- 1988-01-22 HU HU88261A patent/HU200487B/hu unknown
- 1988-01-22 DD DD88312394A patent/DD267512A5/de unknown
- 1988-01-22 FI FI880280A patent/FI90091C/fi not_active IP Right Cessation
- 1988-01-22 DD DD88312393A patent/DD290214A5/de unknown
- 1988-01-22 FI FI880281A patent/FI90088C/fi not_active IP Right Cessation
- 1988-01-22 ZA ZA88447A patent/ZA88447B/xx unknown
- 1988-01-22 DK DK198800290A patent/DK175720B1/da not_active IP Right Cessation
- 1988-01-22 RU SU884355079A patent/RU1806198C/ru active
- 1988-01-22 ZA ZA88448A patent/ZA88448B/xx unknown
- 1988-01-22 HU HU88260D patent/HU201973B/hu unknown
- 1988-01-22 CN CN88100649A patent/CN1056883C/zh not_active Expired - Lifetime
- 1988-01-22 YU YU11988A patent/YU47878B/sh unknown
- 1988-01-22 JP JP63012462A patent/JPH0681757B2/ja not_active Expired - Lifetime
- 1988-01-22 ZA ZA88449A patent/ZA88449B/xx unknown
- 1988-01-22 AR AR88309888A patent/AR241798A1/es active
- 1988-01-22 IE IE16188A patent/IE61066B1/en not_active IP Right Cessation
- 1988-01-22 DK DK028988A patent/DK28988A/da not_active Application Discontinuation
- 1988-01-22 KR KR1019880000470A patent/KR900004419B1/ko not_active IP Right Cessation
- 1988-01-23 KR KR1019880000506A patent/KR910002225B1/ko not_active IP Right Cessation
- 1988-01-23 JP JP63011881A patent/JPH0817693B2/ja not_active Expired - Lifetime
- 1988-01-25 BR BRPI8800271-3A patent/BR8800271A/pt not_active IP Right Cessation
-
1991
- 1991-02-15 AU AU71110/91A patent/AU631298B2/en not_active Expired
-
1993
- 1993-04-08 GR GR930400638T patent/GR3007586T3/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Patent granted |
Owner name: PFIZER INC. |
|
BB | Publication of examined application | ||
FG | Patent granted |
Owner name: PFIZER INC. |
|
MA | Patent expired |