FI751133A - - Google Patents
Info
- Publication number
- FI751133A FI751133A FI751133A FI751133A FI751133A FI 751133 A FI751133 A FI 751133A FI 751133 A FI751133 A FI 751133A FI 751133 A FI751133 A FI 751133A FI 751133 A FI751133 A FI 751133A
- Authority
- FI
- Finland
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI780202A FI780202A (fi) | 1974-04-20 | 1978-01-23 | Foerfarande foer framstaellning av ett huvudsakligen rent salt av klavulansyra |
FI780201A FI58332C (fi) | 1974-04-20 | 1978-01-23 | Foerfarande foer framstaellning av estrar av klavulansyra |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB17410/74A GB1508977A (en) | 1974-04-20 | 1974-04-20 | Beta-lactam antibiotic from streptomyces clavuligerus |
GB2771574 | 1974-06-21 | ||
GB4365174 | 1974-10-09 | ||
GB5352574 | 1974-12-11 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI751133A true FI751133A (pl) | 1975-10-21 |
FI54144B FI54144B (fi) | 1978-06-30 |
FI54144C FI54144C (fi) | 1978-10-10 |
Family
ID=27448389
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI751133A FI54144C (fi) | 1974-04-20 | 1975-04-16 | Foerfarande foer framstaellning av klavulansyra eller ett salt daerav |
Country Status (26)
Country | Link |
---|---|
US (5) | US4427690A (pl) |
JP (7) | JPS521996B2 (pl) |
AR (3) | AR206627A1 (pl) |
CA (1) | CA1059050A (pl) |
CH (2) | CH629252A5 (pl) |
CY (1) | CY1078A (pl) |
DD (2) | DD121799A5 (pl) |
DE (4) | DE2559411C2 (pl) |
DK (1) | DK141254B (pl) |
FI (1) | FI54144C (pl) |
FR (1) | FR2267778B1 (pl) |
HK (1) | HK54780A (pl) |
IE (1) | IE41109B1 (pl) |
IL (1) | IL47087A (pl) |
IN (1) | IN140042B (pl) |
KE (1) | KE3076A (pl) |
LU (1) | LU72322A1 (pl) |
MY (1) | MY8100195A (pl) |
NL (1) | NL163824C (pl) |
NO (3) | NO145247C (pl) |
NZ (1) | NZ177159A (pl) |
OA (1) | OA05203A (pl) |
PH (1) | PH16474A (pl) |
RO (2) | RO77320A (pl) |
SE (8) | SE422063B (pl) |
YU (3) | YU39941B (pl) |
Families Citing this family (94)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE41109B1 (en) | 1974-04-20 | 1979-10-24 | Beecham Group Ltd | Novel -lactam antibiotic from streptomyces clavuligerus |
YU40452B (en) * | 1975-02-07 | 1986-02-28 | Beecham Group Plc | Process for the elimination of contaminating impurities from clavulinic acid |
JPS596796Y2 (ja) * | 1975-04-04 | 1984-03-01 | 株式会社東芝 | 脱水兼用洗濯機 |
US6048977C1 (en) * | 1975-04-17 | 2001-10-16 | Smithkline Beecham Plc | Clavulanic acid and salts thereof |
US6218380B1 (en) * | 1975-04-17 | 2001-04-17 | Smithkline Beecham P.L.C. | Pharmaceutical compositions |
GB1563103A (en) * | 1975-10-13 | 1980-03-19 | Beecham Group Ltd | Process for the preparation of clavulanic acid |
US4230622A (en) * | 1975-12-17 | 1980-10-28 | Glaxo Laboratories Limited | Halogen derivatives of clavulaic acid |
GB1515241A (en) * | 1976-01-27 | 1978-06-21 | Beecham Group Ltd | Beta-lactam antibiotics |
IT1078465B (it) * | 1976-06-08 | 1985-05-08 | Glaxo Lab Ltd | Composti fungicidi per agricoltura composizioni che li contengono e procedimento per produrli |
GB1562802A (en) * | 1976-06-26 | 1980-03-19 | Beecham Group Ltd | Pharmaceutical compositions containing containing clavulanic acid |
GB1562902A (en) * | 1976-06-30 | 1980-03-19 | Beecham Group Ltd | Pharmaceutical compositions containing clavulanic acid |
GB1578739A (en) * | 1976-07-23 | 1980-11-05 | Beecham Group Ltd | Amine salts of clavulanic acid methods for their preparation and compositions containing them |
GB1594001A (en) * | 1977-03-16 | 1981-07-30 | Beecham Group Ltd | Pellets suitable for use in the testing of microorganisms |
GB1582884A (en) * | 1977-05-19 | 1981-01-14 | Beecham Group Ltd | Clavulanic acid derivatives their preparation and use |
DE2912511C2 (de) * | 1977-06-07 | 1982-06-24 | Pfizer Inc., 10017 New York, N.Y. | Pharmazeutische Zusammensetzung, enthaltend Penicillansäure |
JO984B1 (en) * | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
JPS54126735A (en) * | 1978-03-24 | 1979-10-02 | Toyama Chem Co Ltd | Bactericidal composition for medical use |
DE2964817D1 (en) * | 1978-09-06 | 1983-03-24 | Beecham Group Plc | Pharmaceutical compositions containing two beta-lactam derivatives |
JPS5545906U (pl) * | 1978-09-21 | 1980-03-26 | ||
US4202819A (en) * | 1979-05-04 | 1980-05-13 | Hoffman-La Roche Inc. | 2-(3-Alanyl)clavam antibiotic |
ZA804670B (en) * | 1979-08-03 | 1981-07-29 | Beecham Group Ltd | Derivatives of clavulanic acid, a process for their preparation and their use |
DE3063683D1 (en) * | 1979-08-24 | 1983-07-14 | Beecham Group Plc | Amine salt of clavulanic acid, its preparation and use |
EP0053893B1 (en) * | 1980-12-09 | 1985-03-20 | Beecham Group Plc | Derivatives of clavulanic acid, their preparation and their use |
US4562182A (en) * | 1980-12-23 | 1985-12-31 | Beecham Group P.L.C. | Compounds containing beta-lactams |
JPS58361A (ja) * | 1981-06-22 | 1983-01-05 | Kurosaki Refract Co Ltd | 溶融金属鋳造用ノズル |
US4533542A (en) * | 1983-08-22 | 1985-08-06 | Eli Lilly And Company | Pharmaceutical compositions for storage in plastic containers and process therefor |
US4684643A (en) * | 1983-08-22 | 1987-08-04 | Eli Lilly And Company | Pharmaceutical compositions for storage in plastic containers and process therefor |
IT1207982B (it) * | 1983-10-07 | 1989-06-01 | Lisapharma Spa | Composizioni farmaceutiche adattivita' antibiotica. |
JPS60151610U (ja) * | 1984-03-22 | 1985-10-08 | 住友重機械工業株式会社 | 回転ホイ−ル式連続金属押出装置におけるアバツトメント |
JPS6155889A (ja) * | 1984-08-28 | 1986-03-20 | 松下電器産業株式会社 | 高周波加熱装置 |
US4757066A (en) * | 1984-10-15 | 1988-07-12 | Sankyo Company Limited | Composition containing a penem or carbapenem antibiotic and the use of the same |
DE3725375A1 (de) * | 1987-07-31 | 1989-02-09 | Bayer Ag | Stabile oxapenem-3-carbonsaeuren |
GB9009446D0 (en) * | 1990-04-26 | 1990-06-20 | Beecham Group Plc | Veterinary composition |
DE4027928A1 (de) * | 1990-09-04 | 1992-03-05 | Bayer Ag | Neue 2-tert.substituierte methyl-oxapenem-3-carbonsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung |
DE4030706A1 (de) * | 1990-09-28 | 1992-04-02 | Bayer Ag | Neue 3-substituierte cephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
GB9201639D0 (en) * | 1992-01-25 | 1992-03-11 | Smithkline Beecham Plc | Pharmaceutical formulations |
AT400033B (de) * | 1992-03-10 | 1995-09-25 | Biochemie Gmbh | Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben |
AT399155B (de) * | 1992-03-26 | 1995-03-27 | Lek Tovarna Farmacevtskih | Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung |
EP1034784A3 (en) * | 1993-01-22 | 2001-06-27 | Smithkline Beecham Plc | Pharmaceutical formulations containing clavulanic acid and an antibacterial agent |
US5821364A (en) * | 1993-03-26 | 1998-10-13 | Gist-Brocades N.V. | Diamine salts of clavulanic acid |
EP0719778A1 (en) * | 1993-03-26 | 1996-07-03 | Gist-Brocades N.V. | Diamine salts of clavulanic acid |
US5760218A (en) * | 1993-03-26 | 1998-06-02 | Gist-Brocades N.V. | Diamine salts of clavulanic acid |
US5741903A (en) * | 1993-03-26 | 1998-04-21 | Gist-Brocades N.V. | Diamine salts for purification of clavulanic acid |
GB9315393D0 (en) | 1993-07-24 | 1993-09-08 | Smithkline Beecham Plc | Novel product |
US20030219867A1 (en) * | 1993-07-24 | 2003-11-27 | Smithkline Beecham Plc | Clavulanic acid dehydrogenase, preparation and use for the production of clavulanic acid |
SI9400107A (en) * | 1994-03-02 | 1995-10-31 | Lek Tovarna Farmacevtskih | New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804. |
US20030109503A1 (en) * | 1995-06-06 | 2003-06-12 | Smithkline Beecham P.L.C. | Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics |
GB9515809D0 (en) * | 1995-08-02 | 1995-10-04 | Smithkline Beecham Plc | Process |
SI9500265A1 (en) | 1995-08-28 | 1997-02-28 | Lek Tovarna Farmacevtskih | Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration |
BR9610396A (pt) * | 1995-09-07 | 1999-07-06 | Smithkline Beecham Corp | Formulação farmacêutica |
AT403375B (de) * | 1995-11-15 | 1998-01-26 | Biochemie Gmbh | Verfahren zur fällung von alkalisalzen der clavulansäure |
US20030124187A1 (en) * | 1997-02-14 | 2003-07-03 | Smithkline Beecham Laboratoires Pharmaceutiques, | Pharmaceutical formulations comprising amoxycillin and clavulanate |
AU6400098A (en) * | 1997-02-20 | 1998-09-09 | Gist-Brocades B.V. | Fermentative production of valuable compounds on an industrial scale using chemically defined media |
AR015825A1 (es) * | 1997-05-28 | 2001-05-30 | Gist Brocades Bv | Produccion fermentativa de acido clavulanico bajo condiciones controladas de fosfato |
CA2336363A1 (en) * | 1998-07-03 | 2000-01-13 | Dsm N.V. | Fermentation process to produce clavulanic acid at a low concentration of free amino acids |
US7250176B1 (en) * | 1999-04-13 | 2007-07-31 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection |
US6878386B1 (en) | 1999-04-13 | 2005-04-12 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate |
US6294199B1 (en) * | 1999-04-13 | 2001-09-25 | Beecham Pharmaceuticals (Pte) Limited | Method of treating a bacterial infection comprising administering amoxycillin |
US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
US6565882B2 (en) | 2000-02-24 | 2003-05-20 | Advancis Pharmaceutical Corp | Antibiotic composition with inhibitor |
US6756057B2 (en) | 2000-10-12 | 2004-06-29 | Beecham Pharmaceuticals (Pte) Limited | Amoxicillin and potassium clavulanate dosage form |
WO2002030392A2 (en) | 2000-10-12 | 2002-04-18 | Beecham Pharmaceuticals (Pte) Limited | Formulation containing amoxicillin |
US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
US6541014B2 (en) | 2000-10-13 | 2003-04-01 | Advancis Pharmaceutical Corp. | Antiviral product, use and formulation thereof |
IL150907A (en) * | 2002-07-25 | 2007-07-04 | Stephan Cherkez | Process for the preparation of stable amorphous calcium pseudomonate |
EP1648418A4 (en) | 2003-07-21 | 2011-11-16 | Middlebrook Pharmaceuticals Inc | ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION |
US8313776B2 (en) | 2003-07-21 | 2012-11-20 | Shionogi Inc. | Antibiotic product, use and formulation thereof |
AU2004258953B2 (en) | 2003-07-21 | 2011-02-10 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
EP1653925A1 (en) | 2003-08-11 | 2006-05-10 | Advancis Pharmaceutical Corporation | Robust pellet |
AU2004264356B2 (en) | 2003-08-12 | 2011-01-27 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
JP5686494B2 (ja) | 2003-08-29 | 2015-03-18 | シオノギ インコーポレイテッド | 抗生物質製剤、その使用法及び作成方法 |
WO2005027877A1 (en) | 2003-09-15 | 2005-03-31 | Advancis Pharmaceutical Corporation | Antibiotic product, use and formulation thereof |
JP2008505124A (ja) | 2004-07-02 | 2008-02-21 | アドバンシス ファーマスーティカル コーポレイション | パルス送達用錠剤 |
US20060194285A1 (en) * | 2005-02-08 | 2006-08-31 | Wei Lian | Biological production of clavulanic acid and related compounds |
DE102005009277B4 (de) * | 2005-02-25 | 2008-07-31 | Johnson Controls Interiors Gmbh & Co. Kg | Halterung für eine Komponente |
CN102988362B (zh) * | 2005-12-07 | 2014-11-05 | 巴斯利尔药物股份公司 | 单环-内酰胺类抗生素与β-内酰胺酶抑制剂的有效的联合应用 |
US8357394B2 (en) | 2005-12-08 | 2013-01-22 | Shionogi Inc. | Compositions and methods for improved efficacy of penicillin-type antibiotics |
US8778924B2 (en) | 2006-12-04 | 2014-07-15 | Shionogi Inc. | Modified release amoxicillin products |
US20070218038A1 (en) | 2006-03-17 | 2007-09-20 | Pegasus Biologics, Inc. | Stabilized, sterilized collagen scaffolds with active adjuncts attached |
US8299052B2 (en) * | 2006-05-05 | 2012-10-30 | Shionogi Inc. | Pharmaceutical compositions and methods for improved bacterial eradication |
EP2575781A1 (en) | 2010-06-03 | 2013-04-10 | Mahmut Bilgic | Production method for the effervescent formulation comprising cephalosporin and potassium clavulanate |
WO2014089365A1 (en) | 2012-12-07 | 2014-06-12 | Venatorx Pharmaceuticals, Inc | Beta-lactamase inhibitors |
JP6346904B2 (ja) | 2013-01-10 | 2018-06-20 | ベナトルクス ファーマシューティカルズ,インク. | ベータ−ラクタマーゼ阻害剤 |
US9944658B2 (en) | 2013-03-14 | 2018-04-17 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
US20150361108A1 (en) * | 2014-06-11 | 2015-12-17 | VenatoRx Pharmaceuticals, Inc. | Orally bioavailable beta-lactamase inhibitors |
US9511142B2 (en) | 2014-06-11 | 2016-12-06 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
PT3154989T (pt) | 2014-06-11 | 2021-05-18 | Venatorx Pharmaceuticals Inc | Inibidores de beta-lactamase |
EP3347008B1 (en) | 2015-09-11 | 2022-03-09 | Venatorx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
WO2017100537A1 (en) | 2015-12-10 | 2017-06-15 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
JP2019527214A (ja) | 2016-07-14 | 2019-09-26 | アカオジェン インコーポレイテッド | 細菌感染症の処置における使用のためのセフチブテンとクラブラン酸の組み合わせ |
EP3494121B1 (en) | 2016-08-04 | 2021-10-06 | Venatorx Pharmaceuticals, Inc. | Boron-containing compounds |
US11267826B2 (en) | 2017-05-26 | 2022-03-08 | VenatoRx Pharmaceuticals, Inc. | Penicillin-binding protein inhibitors |
EP3630782A4 (en) | 2017-05-26 | 2021-03-03 | Venatorx Pharmaceuticals, Inc. | PENICILLIN BINDING PROTEIN INHIBITORS |
CN114846332A (zh) | 2019-10-25 | 2022-08-02 | 仪器实验室公司 | 与酶生物传感器相容的杀生物剂组合物及其使用方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3801464A (en) | 1972-02-09 | 1974-04-02 | Lilly Co Eli | Antibiotic a16886 and process for production thereof |
IE41109B1 (en) | 1974-04-20 | 1979-10-24 | Beecham Group Ltd | Novel -lactam antibiotic from streptomyces clavuligerus |
US4140764A (en) * | 1974-12-18 | 1979-02-20 | Beecham Group Limited | β-Lactamase inhibitors and process for their preparation |
US4123540A (en) * | 1974-12-18 | 1978-10-31 | Beecham Group Limited | Isoclavulanic acid as an antibacterial and a β-lactamase inhibitor |
YU40452B (en) * | 1975-02-07 | 1986-02-28 | Beecham Group Plc | Process for the elimination of contaminating impurities from clavulinic acid |
US4144242A (en) * | 1975-02-07 | 1979-03-13 | Glaxo Laboratories Limited | Process for the purification of clavulanic acid |
JO984B1 (en) * | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
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1975
- 1975-04-08 IE IE792/75A patent/IE41109B1/xx not_active IP Right Cessation
- 1975-04-08 NZ NZ177159A patent/NZ177159A/xx unknown
- 1975-04-09 YU YU908/75A patent/YU39941B/xx unknown
- 1975-04-11 CY CY1078A patent/CY1078A/xx unknown
- 1975-04-11 FR FR7511344A patent/FR2267778B1/fr not_active Expired
- 1975-04-14 IL IL47087A patent/IL47087A/xx unknown
- 1975-04-14 IN IN743/CAL/75A patent/IN140042B/en unknown
- 1975-04-16 FI FI751133A patent/FI54144C/fi not_active IP Right Cessation
- 1975-04-18 DE DE2559411A patent/DE2559411C2/de not_active Expired
- 1975-04-18 DK DK167275AA patent/DK141254B/da not_active IP Right Cessation
- 1975-04-18 AR AR258435A patent/AR206627A1/es active
- 1975-04-18 DE DE2560074A patent/DE2560074C2/de not_active Expired
- 1975-04-18 CA CA224,970A patent/CA1059050A/en not_active Expired
- 1975-04-18 LU LU72322A patent/LU72322A1/xx unknown
- 1975-04-18 DE DE19752559410 patent/DE2559410A1/de not_active Ceased
- 1975-04-18 DD DD185542A patent/DD121799A5/xx unknown
- 1975-04-18 SE SE7504541A patent/SE422063B/xx not_active IP Right Cessation
- 1975-04-18 NL NL7504621.A patent/NL163824C/xx not_active IP Right Cessation
- 1975-04-18 NO NO751407A patent/NO145247C/no unknown
- 1975-04-18 DE DE2517316A patent/DE2517316C2/de not_active Expired
- 1975-04-18 DD DD7500193531A patent/DD132297A5/xx unknown
- 1975-04-19 OA OA55480A patent/OA05203A/xx unknown
- 1975-04-19 RO RO7595311A patent/RO77320A/ro unknown
- 1975-04-19 JP JP50048086A patent/JPS521996B2/ja not_active Expired
- 1975-04-19 RO RO7582037A patent/RO69984A/ro unknown
- 1975-04-19 JP JP50048087A patent/JPS5246957B2/ja not_active Expired
- 1975-04-21 CH CH506075A patent/CH629252A5/de active Protection Beyond IP Right Term
- 1975-04-21 PH PH17082A patent/PH16474A/en unknown
- 1975-11-28 AR AR261404A patent/AR219050A1/es active
- 1975-11-28 AR AR261403A patent/AR216430A1/es active
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1976
- 1976-09-24 US US06/726,224 patent/US4427690A/en not_active Expired - Lifetime
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1977
- 1977-04-05 JP JP4025877A patent/JPS532495A/ja active Granted
- 1977-04-05 JP JP4025977A patent/JPS533588A/ja active Granted
- 1977-04-05 JP JP4026077A patent/JPS533589A/ja active Granted
- 1977-04-05 JP JP4025777A patent/JPS532494A/ja active Granted
- 1977-04-05 JP JP4026177A patent/JPS533590A/ja active Pending
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1978
- 1978-07-13 US US05/924,174 patent/US4556559A/en not_active Expired - Lifetime
- 1978-10-27 SE SE7811203A patent/SE443562B/sv not_active IP Right Cessation
- 1978-10-27 SE SE7811201A patent/SE446687B/sv not_active IP Right Cessation
- 1978-10-27 SE SE7811200A patent/SE435286B/sv not_active IP Right Cessation
- 1978-10-27 SE SE7811202A patent/SE435287B/sv not_active IP Right Cessation
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1979
- 1979-06-12 NO NO791956A patent/NO150838C/no unknown
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1980
- 1980-06-20 NO NO801852A patent/NO801852L/no unknown
- 1980-08-29 KE KE3076A patent/KE3076A/xx unknown
- 1980-09-25 HK HK547/80A patent/HK54780A/xx unknown
- 1980-12-22 CH CH947280A patent/CH630631A5/de not_active IP Right Cessation
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1981
- 1981-06-09 US US06/272,030 patent/US4526783A/en not_active Expired - Lifetime
- 1981-10-02 SE SE8105829A patent/SE453600B/sv not_active IP Right Cessation
- 1981-11-23 YU YU2744/81A patent/YU42745B/xx unknown
- 1981-11-23 YU YU2743/81A patent/YU42744B/xx unknown
- 1981-12-03 US US06/327,253 patent/US4525352A/en not_active Expired - Lifetime
- 1981-12-14 US US06330456 patent/US4560552C1/en not_active Expired - Lifetime
- 1981-12-30 MY MY195/81A patent/MY8100195A/xx unknown
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1983
- 1983-11-16 SE SE8306328A patent/SE8306328D0/xx unknown
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1986
- 1986-12-16 SE SE8605405A patent/SE8605405D0/xx unknown
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Date | Code | Title | Description |
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MA | Patent expired | ||
MA | Patent expired |
Owner name: BEECHAM GROUP LIMITED |