FI63744C - Foerfarande foer framstaellning av nya spasmolytiska tyrosinderivat - Google Patents
Foerfarande foer framstaellning av nya spasmolytiska tyrosinderivat Download PDFInfo
- Publication number
- FI63744C FI63744C FI750256A FI750256A FI63744C FI 63744 C FI63744 C FI 63744C FI 750256 A FI750256 A FI 750256A FI 750256 A FI750256 A FI 750256A FI 63744 C FI63744 C FI 63744C
- Authority
- FI
- Finland
- Prior art keywords
- formula
- cbz
- group
- give
- alk
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT6728674 | 1974-02-01 | ||
IT67286/74A IT1062206B (it) | 1974-02-01 | 1974-02-01 | Derivati della tirosina attivi sulla muscolatura liscia |
Publications (3)
Publication Number | Publication Date |
---|---|
FI750256A FI750256A (fr) | 1975-08-02 |
FI63744B FI63744B (fi) | 1983-04-29 |
FI63744C true FI63744C (fi) | 1983-08-10 |
Family
ID=11301149
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI750256A FI63744C (fi) | 1974-02-01 | 1975-01-30 | Foerfarande foer framstaellning av nya spasmolytiska tyrosinderivat |
FI750255A FI61479C (fi) | 1974-02-01 | 1975-01-30 | Foerfarande foer framstaellning av spasmolytiska nya d,l-tyrosinderivat |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI750255A FI61479C (fi) | 1974-02-01 | 1975-01-30 | Foerfarande foer framstaellning av spasmolytiska nya d,l-tyrosinderivat |
Country Status (19)
Country | Link |
---|---|
US (1) | US4004008A (fr) |
JP (2) | JPS5417729B2 (fr) |
AT (2) | AT343632B (fr) |
BE (1) | BE824995A (fr) |
CA (2) | CA1047498A (fr) |
CH (2) | CH605657A5 (fr) |
DE (1) | DE2503992C2 (fr) |
ES (1) | ES434323A1 (fr) |
FI (2) | FI63744C (fr) |
FR (1) | FR2259592B1 (fr) |
GB (1) | GB1467927A (fr) |
HK (1) | HK38979A (fr) |
HU (2) | HU174825B (fr) |
IN (1) | IN139364B (fr) |
IT (1) | IT1062206B (fr) |
NL (1) | NL167683C (fr) |
NO (2) | NO144211C (fr) |
SE (2) | SE410850B (fr) |
ZA (1) | ZA75530B (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5225243A (en) * | 1975-08-20 | 1977-02-25 | Toshiba Electric Equip Corp | Distributing panel |
US4579866A (en) * | 1984-05-29 | 1986-04-01 | Usv Pharmaceutical Corp. | Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents |
CA1320734C (fr) * | 1986-02-04 | 1993-07-27 | Suntory Limited | Derive pyrrolidineamide d'acide acylamine; composition pharmaceutique a base de ce derive |
US5198458A (en) * | 1986-02-04 | 1993-03-30 | Suntory Limited | Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same |
NZ239846A (en) * | 1990-09-27 | 1994-11-25 | Merck & Co Inc | Sulphonamide derivatives and pharmaceutical compositions thereof |
IL99537A (en) * | 1990-09-27 | 1995-11-27 | Merck & Co Inc | Fibrinogen receptor antagonists and pharmaceutical preparations containing them |
US5258407A (en) * | 1991-12-31 | 1993-11-02 | Sterling Winthrop Inc. | 3,4-disubstituted phenols-immunomodulating agents |
US5206373A (en) * | 1992-02-28 | 1993-04-27 | Merck & Co., Inc. | Process for preparing fibrinogen receptor antagonists |
DE10204951A1 (de) * | 2002-02-06 | 2003-08-14 | Basf Ag | Phenylalaninderivate als Herbizide |
WO2005061443A2 (fr) * | 2003-12-19 | 2005-07-07 | Basf Aktiengesellschaft | Amides de phenylalanine a substitution benzoyle |
RU2394560C2 (ru) * | 2005-07-19 | 2010-07-20 | Дайити Санкио Компани, Лимитед | Замещенное пропанамидное производное и фармацевтическая композиция, содержащая такое производное |
WO2011094890A1 (fr) | 2010-02-02 | 2011-08-11 | Argusina Inc. | Dérivés phénylalanines et leur utilisation comme modulateurs non peptidiques du récepteur de glp-1 |
JP2013530963A (ja) * | 2010-06-09 | 2013-08-01 | レセプトス インコーポレイテッド | 新規のglp−1受容体安定化薬および調節薬 |
ES2634716T3 (es) | 2011-05-31 | 2017-09-28 | Celgene International Ii Sàrl | Nuevos estabilizantes y moduladores del receptor GLP-1 |
US8778923B2 (en) | 2011-12-12 | 2014-07-15 | Receptos, Inc. | GLP-1 receptor modulators |
CN102659619A (zh) * | 2012-04-18 | 2012-09-12 | 上海骏捷生化科技有限公司 | 一种合成酪氨酸衍生物的方法 |
CN103508921B (zh) * | 2012-06-21 | 2015-09-30 | 贵州百灵企业集团制药股份有限公司 | 一种苯丙氨醇化合物的制备方法 |
CN103508920B (zh) * | 2012-06-21 | 2016-03-02 | 贵州百灵企业集团制药股份有限公司 | 一种苯丙氨醇化合物的光学异构体的制备方法及其用途 |
BR112015031040A8 (pt) | 2013-06-11 | 2018-01-02 | Receptos Inc | Novos moduladores do receptor de glp-1 |
EA032525B1 (ru) | 2014-07-25 | 2019-06-28 | Селджин Интернэшнл Ii Сарл | Модуляторы рецептора glp-1 |
MX2017007494A (es) | 2014-12-10 | 2017-10-31 | Celgene Int Ii Sarl | Moduladores del receptor de peptido 1 tipo glucagon. |
CN107417560B (zh) * | 2017-03-30 | 2020-05-22 | 上海常丰生物医药科技有限公司 | 一种合成盐酸替罗酰胺的方法 |
CN110015978B (zh) * | 2019-04-29 | 2021-03-19 | 康化(上海)新药研发有限公司 | O-[2-[[叔丁氧羰基]氨基]乙基]-n-[芴甲氧羰基]-l-酪氨酸的合成方法 |
CN115850107A (zh) * | 2022-11-30 | 2023-03-28 | 苏州诚和医药化学有限公司 | 一种工业化合成盐酸替罗酰胺的方法 |
-
1974
- 1974-02-01 IT IT67286/74A patent/IT1062206B/it active Protection Beyond IP Right Term
-
1975
- 1975-01-22 GB GB287875A patent/GB1467927A/en not_active Expired
- 1975-01-24 ZA ZA00750530A patent/ZA75530B/xx unknown
- 1975-01-29 IN IN179/CAL/75A patent/IN139364B/en unknown
- 1975-01-30 BE BE152889A patent/BE824995A/fr not_active IP Right Cessation
- 1975-01-30 NO NO750288A patent/NO144211C/no unknown
- 1975-01-30 CA CA219,027A patent/CA1047498A/fr not_active Expired
- 1975-01-30 CH CH110875A patent/CH605657A5/xx not_active IP Right Cessation
- 1975-01-30 CH CH110975A patent/CH605658A5/xx not_active IP Right Cessation
- 1975-01-30 FI FI750256A patent/FI63744C/fi not_active IP Right Cessation
- 1975-01-30 NO NO750287A patent/NO144210C/no unknown
- 1975-01-30 CA CA75219028A patent/CA1048503A/fr not_active Expired
- 1975-01-30 FI FI750255A patent/FI61479C/fi not_active IP Right Cessation
- 1975-01-31 SE SE7501114A patent/SE410850B/xx not_active IP Right Cessation
- 1975-01-31 ES ES434323A patent/ES434323A1/es not_active Expired
- 1975-01-31 AT AT74675A patent/AT343632B/de not_active IP Right Cessation
- 1975-01-31 FR FR7503079A patent/FR2259592B1/fr not_active Expired
- 1975-01-31 HU HU75RO820A patent/HU174825B/hu unknown
- 1975-01-31 NL NL7501193A patent/NL167683C/xx not_active IP Right Cessation
- 1975-01-31 HU HU75RO821A patent/HU175156B/hu unknown
- 1975-01-31 DE DE2503992A patent/DE2503992C2/de not_active Expired
- 1975-01-31 SE SE7501115A patent/SE413094B/xx unknown
- 1975-01-31 JP JP1328575A patent/JPS5417729B2/ja not_active Expired
- 1975-01-31 AT AT74575A patent/AT342026B/de not_active IP Right Cessation
- 1975-01-31 JP JP1326675A patent/JPS5417728B2/ja not_active Expired
- 1975-02-03 US US05/546,481 patent/US4004008A/en not_active Expired - Lifetime
-
1979
- 1979-06-14 HK HK389/79A patent/HK38979A/xx unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed |
Owner name: ROTTA RESEARCH LABORATORIUM S.P.A. |