BE824995A - Nouveaux derives de tyrosine doues d'activite sur les muscles lisses - Google Patents

Nouveaux derives de tyrosine doues d'activite sur les muscles lisses

Info

Publication number
BE824995A
BE824995A BE152889A BE152889A BE824995A BE 824995 A BE824995 A BE 824995A BE 152889 A BE152889 A BE 152889A BE 152889 A BE152889 A BE 152889A BE 824995 A BE824995 A BE 824995A
Authority
BE
Belgium
Prior art keywords
activity
smooth muscles
tyrosine derivatives
new tyrosine
new
Prior art date
Application number
BE152889A
Other languages
English (en)
Inventor
F Makovec
L Rovati
P Senin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE824995A publication Critical patent/BE824995A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
BE152889A 1974-02-01 1975-01-30 Nouveaux derives de tyrosine doues d'activite sur les muscles lisses BE824995A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT67286/74A IT1062206B (it) 1974-02-01 1974-02-01 Derivati della tirosina attivi sulla muscolatura liscia

Publications (1)

Publication Number Publication Date
BE824995A true BE824995A (fr) 1975-05-15

Family

ID=11301149

Family Applications (1)

Application Number Title Priority Date Filing Date
BE152889A BE824995A (fr) 1974-02-01 1975-01-30 Nouveaux derives de tyrosine doues d'activite sur les muscles lisses

Country Status (19)

Country Link
US (1) US4004008A (fr)
JP (2) JPS5417728B2 (fr)
AT (2) AT342026B (fr)
BE (1) BE824995A (fr)
CA (2) CA1047498A (fr)
CH (2) CH605657A5 (fr)
DE (1) DE2503992C2 (fr)
ES (1) ES434323A1 (fr)
FI (2) FI61479C (fr)
FR (1) FR2259592B1 (fr)
GB (1) GB1467927A (fr)
HK (1) HK38979A (fr)
HU (2) HU174825B (fr)
IN (1) IN139364B (fr)
IT (1) IT1062206B (fr)
NL (1) NL167683C (fr)
NO (2) NO144210C (fr)
SE (2) SE410850B (fr)
ZA (1) ZA75530B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5225243A (en) * 1975-08-20 1977-02-25 Toshiba Electric Equip Corp Distributing panel
US4579866A (en) * 1984-05-29 1986-04-01 Usv Pharmaceutical Corp. Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents
CA1320734C (fr) * 1986-02-04 1993-07-27 Suntory Limited Derive pyrrolidineamide d'acide acylamine; composition pharmaceutique a base de ce derive
US5198458A (en) * 1986-02-04 1993-03-30 Suntory Limited Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same
IL99537A (en) * 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical preparations containing them
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
US5258407A (en) * 1991-12-31 1993-11-02 Sterling Winthrop Inc. 3,4-disubstituted phenols-immunomodulating agents
US5206373A (en) * 1992-02-28 1993-04-27 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
DE10204951A1 (de) * 2002-02-06 2003-08-14 Basf Ag Phenylalaninderivate als Herbizide
EA200601105A1 (ru) * 2003-12-19 2006-12-29 Басф Акциенгезельшафт Замещённые бензоилом фенилаланин-амиды
BRPI0613423A2 (pt) * 2005-07-19 2012-12-11 Daiichi Sankyo Co Ltd composição farmacêutica, composto ou um seu sal farmaceuticamente aceitável, e, uso de um composto ou um sal farmaceuticamente aceitável do mesmo
WO2011094890A1 (fr) 2010-02-02 2011-08-11 Argusina Inc. Dérivés phénylalanines et leur utilisation comme modulateurs non peptidiques du récepteur de glp-1
US8501982B2 (en) * 2010-06-09 2013-08-06 Receptos, Inc. GLP-1 receptor stabilizers and modulators
US9278910B2 (en) 2011-05-31 2016-03-08 Receptos, Inc. GLP-1 receptor stabilizers and modulators
JP6061949B2 (ja) 2011-12-12 2017-01-18 レセプトス エルエルシー 糖尿病などの疾患の治療のためのｇｌｐ−１受容体モジュレーターとして作用する４つの環を含むカルボン酸誘導体
CN102659619A (zh) * 2012-04-18 2012-09-12 上海骏捷生化科技有限公司 一种合成酪氨酸衍生物的方法
CN103508920B (zh) * 2012-06-21 2016-03-02 贵州百灵企业集团制药股份有限公司 一种苯丙氨醇化合物的光学异构体的制备方法及其用途
CN103508921B (zh) * 2012-06-21 2015-09-30 贵州百灵企业集团制药股份有限公司 一种苯丙氨醇化合物的制备方法
EA030857B1 (ru) 2013-06-11 2018-10-31 Селджин Интернэшнл Ii Сарл Новые модуляторы рецептора glp-1
SG11201700364PA (en) 2014-07-25 2017-02-27 Celgene Internat Ii Sarl Novel glp-1 receptor modulators
EP3230276B1 (fr) 2014-12-10 2020-09-02 Celgene International II Sarl Modulateurs du récepteur du glp-1
CN107417560B (zh) * 2017-03-30 2020-05-22 上海常丰生物医药科技有限公司 一种合成盐酸替罗酰胺的方法
CN110015978B (zh) * 2019-04-29 2021-03-19 康化（上海）新药研发有限公司 O-[2-[[叔丁氧羰基]氨基]乙基]-n-[芴甲氧羰基]-l-酪氨酸的合成方法
CN115850107A (zh) * 2022-11-30 2023-03-28 苏州诚和医药化学有限公司 一种工业化合成盐酸替罗酰胺的方法

Also Published As

Publication number Publication date
US4004008A (en) 1977-01-18
DE2503992A1 (de) 1975-08-14
NL7501193A (nl) 1975-08-05
JPS50116441A (fr) 1975-09-11
JPS50116442A (fr) 1975-09-11
HU174825B (hu) 1980-03-28
CA1047498A (fr) 1979-01-30
HU175156B (hu) 1980-05-28
SE7501115L (sv) 1975-08-04
AU7775075A (en) 1976-08-05
NL167683C (nl) 1982-01-18
AT342026B (de) 1978-03-10
ES434323A1 (es) 1976-12-16
IT1062206B (it) 1983-09-20
FR2259592B1 (fr) 1978-07-21
FI63744C (fi) 1983-08-10
FI61479C (fi) 1982-08-10
NO144210B (no) 1981-04-06
NO750288L (fr) 1975-08-25
SE413094B (sv) 1980-04-14
NL167683B (nl) 1981-08-17
NO144210C (no) 1981-07-15
IN139364B (fr) 1976-06-12
NO144211C (no) 1981-07-15
NO144211B (no) 1981-04-06
AT343632B (de) 1978-06-12
FI750256A (fr) 1975-08-02
ATA74575A (de) 1977-07-15
SE410850B (sv) 1979-11-12
CA1048503A (fr) 1979-02-13
ATA74675A (de) 1977-10-15
NO750287L (fr) 1975-08-25
FI63744B (fi) 1983-04-29
CH605658A5 (fr) 1978-10-13
JPS5417729B2 (fr) 1979-07-02
CH605657A5 (fr) 1978-10-13
DE2503992C2 (de) 1982-01-21
ZA75530B (en) 1976-01-28
GB1467927A (en) 1977-03-23
JPS5417728B2 (fr) 1979-07-02
SE7501114L (sv) 1975-08-04
FI750255A (fr) 1975-08-02
FI61479B (fi) 1982-04-30
FR2259592A1 (fr) 1975-08-29
HK38979A (en) 1979-06-22

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ROTTA RESEARCH LABORATORIUM S.P.A.

Effective date: 19940131