US5021456A
(en)
|
1988-02-25 |
1991-06-04 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US4943593A
(en)
|
1988-02-25 |
1990-07-24 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5059714A
(en)
|
1988-02-25 |
1991-10-22 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5252608A
(en)
|
1988-02-25 |
1993-10-12 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5182297A
(en)
|
1988-02-25 |
1993-01-26 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US4965288A
(en)
|
1988-02-25 |
1990-10-23 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5120764A
(en)
|
1988-11-01 |
1992-06-09 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US4997854A
(en)
|
1989-08-25 |
1991-03-05 |
Trustees Of Boston University |
Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates
|
US6319494B1
(en)
|
1990-12-14 |
2001-11-20 |
Cell Genesys, Inc. |
Chimeric chains for receptor-associated signal transduction pathways
|
IL104570A0
(en)
|
1992-03-18 |
1993-05-13 |
Yeda Res & Dev |
Chimeric genes and cells transformed therewith
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
AU1583397A
(en)
|
1996-01-30 |
1997-08-22 |
Brigham And Women's Hospital |
Antibodies for modulating cd47-mediated neutrophil transmigration
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
CA2226962A1
(en)
|
1998-02-16 |
1999-08-16 |
Marie Sarfati |
Use of binding agents to cd47 and its ligands in the treatment or the prophylaxis of various inflammatory, autoimmune and allergic diseases and in the treatment of graft rejection
|
EP1244707A1
(de)
|
1999-11-30 |
2002-10-02 |
Eberhard-Karls-Universität Tübingen Universitätsklinikum |
Antikörper gegen signal-regulator-proteine
|
US7658921B2
(en)
|
2000-12-12 |
2010-02-09 |
Medimmune, Llc |
Molecules with extended half-lives, compositions and uses thereof
|
WO2002092784A2
(en)
|
2001-05-15 |
2002-11-21 |
Emory University |
POLYNUCLEOTIDES AND POLYPEPTIDES RELATING TO THE MODULATION OF SIRP α-CD47
|
FR2828206B1
(fr)
|
2001-08-03 |
2004-09-24 |
Centre Nat Rech Scient |
Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US7662925B2
(en)
|
2002-03-01 |
2010-02-16 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
US7841940B2
(en)
|
2003-07-14 |
2010-11-30 |
Astav, Inc |
Human test based on human conceptual capabilities
|
CA2545166A1
(en)
|
2003-11-11 |
2005-05-19 |
Chugai Seiyaku Kabushiki Kaisha |
Humanized anti-cd47 antibody
|
USRE44638E1
(en)
|
2004-05-13 |
2013-12-10 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
CA2591724C
(en)
|
2004-12-17 |
2014-08-05 |
Merck Frosst Canada Ltd. |
2-(phenyl or heterocyclic)-1h-phenantrho[9,10-d]imidazoles as mpges-1 inhibitors
|
US7442716B2
(en)
|
2004-12-17 |
2008-10-28 |
Merck Frosst Canada Ltd. |
2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors
|
US20090142345A1
(en)
|
2005-03-15 |
2009-06-04 |
Takeda Pharmaceutical Company Limited |
Prophylactic/therapeutic agent for cancer
|
JP2008540656A
(ja)
|
2005-05-18 |
2008-11-20 |
ワイス |
Tpl2キナーゼの3−シアノキノリン阻害物質ならびにそれを製造および使用する方法
|
MX2007014258A
(es)
|
2005-05-18 |
2008-01-22 |
Wyeth Corp |
Inhibidores de 4,6-diamino-[1,7]naftiridin-3-carbonitrilo de la tpl2 cinasa y metodos de fabricacion y uso de los mismos.
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之胺基二氮雜呯
|
TWI404537B
(zh)
|
2005-08-19 |
2013-08-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之8-經取代苯并氮雜呯
|
WO2007041635A2
(en)
|
2005-10-03 |
2007-04-12 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
WO2007124589A1
(en)
|
2006-05-02 |
2007-11-08 |
Merck Frosst Canada Ltd. |
Methods for treating or preventing neoplasias
|
US20080131431A1
(en)
|
2006-05-15 |
2008-06-05 |
Viral Logic Systems Technology Corp. |
CD47 related compositions and methods for treating immunological diseases and disorders
|
US8404631B2
(en)
|
2006-05-22 |
2013-03-26 |
The Regents Of The University Of California |
Compositions and methods for the delivery of oxygen
|
ITMI20061053A1
(it)
|
2006-05-30 |
2007-11-30 |
Manuli Rubber Ind Spa |
Raccordo per tubi flessibili per applicazioni oleodinamiche,industriali e aria condizionata,avente caratteristiche di tenuta migliorate.
|
DE102006058450A1
(de)
|
2006-12-12 |
2008-06-19 |
Eberhard-Karls-Universität Tübingen |
Zubereitungen zur Hemmung der Prostaglandin E2 Synthese
|
EA021463B1
(ru)
|
2007-06-29 |
2015-06-30 |
Джилид Сайэнс, Инк. |
Пуриновые производные и их применение в качестве модуляторов толл-подобного рецептора 7
|
EP2388270A3
(en)
|
2007-10-11 |
2012-04-25 |
The Hospital For Sick Children |
Modulation of SIRPa - CD47 interaction for increasing human hematopoietic stem cell engraftment and compounds therefor
|
UY31468A1
(es)
|
2007-11-15 |
2009-07-17 |
|
Derivados bis-(sulfonilamino) en terapia 065
|
TW200930369A
(en)
|
2007-11-15 |
2009-07-16 |
Astrazeneca Ab |
Bis-(sulfonylamino) derivatives in therapy
|
US20090163586A1
(en)
|
2007-12-20 |
2009-06-25 |
Astrazeneca Ab |
Bis-(Sulfonylamino) Derivatives in Therapy 205
|
WO2009103778A1
(en)
|
2008-02-19 |
2009-08-27 |
Novasaid Ab |
Compounds and methods
|
WO2009117987A2
(de)
|
2008-03-26 |
2009-10-01 |
Universität Tübingen |
Verwendung von boswelliasäuren und synthetischen boswelliasäurederivaten zur hemmung der mikrosomalen prostaglandin e2 synthase und des cathepsin g
|
WO2009130242A1
(en)
|
2008-04-23 |
2009-10-29 |
Novasaid Ab |
Low molecular weight derivatives and use thereof in treatment of prostaglandin e synthase related diseases
|
EP2119705A1
(en)
|
2008-05-14 |
2009-11-18 |
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. |
3-Aminocarbozole compound, pharmaceutical composition containing it and preparation method therefor
|
DE102008027331A1
(de)
|
2008-06-07 |
2009-12-10 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Verwendung von Indol-3-carbonsäureestern zur Hemmung der mikrosomalen Prostaglandin E2 Synthase
|
DE102008015432A1
(de)
|
2008-06-12 |
2009-12-17 |
Eberhard-Karls-Universität Tübingen |
Verwendung von Pirinixinsäure-Derivaten zur Hemmung der Prostaglandin E2 Synthese
|
ES2438496T3
(es)
|
2008-08-01 |
2014-01-17 |
Ventirx Pharmaceuticals, Inc. |
Formulaciones de agonistas de receptores de tipo toll y su uso
|
US8652843B2
(en)
|
2008-08-12 |
2014-02-18 |
Oncomed Pharmaceuticals, Inc. |
DDR1-binding agents and methods of use thereof
|
UY32138A
(es)
|
2008-09-25 |
2010-04-30 |
Boehringer Ingelheim Int |
Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables
|
US8450321B2
(en)
|
2008-12-08 |
2013-05-28 |
Gilead Connecticut, Inc. |
6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
|
PE20120106A1
(es)
|
2008-12-09 |
2012-02-20 |
Gilead Sciences Inc |
Moduladores de receptores tipo toll
|
JP2012512640A
(ja)
|
2008-12-19 |
2012-06-07 |
ノバルティス アーゲー |
自己免疫および炎症性障害の処置に使用するための可溶性ポリペプチド
|
WO2010083253A2
(en)
|
2009-01-14 |
2010-07-22 |
Viral Logic Systems Technology Corp. |
Cd47 related compositions and methods for treating immunological diseases and disorders
|
UY32470A
(es)
|
2009-03-05 |
2010-10-29 |
Boehringer Ingelheim Int |
Derivados de 2-{2-cloro-5-[(sustituido) metil]fenilamino} -1-metil]fenilamino}-1-metilbencimidazol-5-carboxamidas-n-(sustituidas) y sus sales fisiológicamente aceptables, composiciones conteniéndolos y aplicaciones
|
TWI491606B
(zh)
|
2009-07-13 |
2015-07-11 |
Gilead Sciences Inc |
調節細胞凋亡信號之激酶的抑制劑
|
DK2467380T3
(en)
|
2009-08-18 |
2017-03-13 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS
|
RU2016125705A
(ru)
|
2009-08-18 |
2018-12-04 |
Вентиркс Фармасьютикалз, Инк. |
Замещенные бензоазепины в качестве модуляторов тoll-подобных рецепторов
|
WO2011023812A1
(en)
|
2009-08-27 |
2011-03-03 |
Novasaid Ab |
Microsomal prostaglandin e synthase-1 (mpges1) inhibitors
|
PL2491035T3
(pl)
|
2009-10-22 |
2018-01-31 |
Gilead Sciences Inc |
Pochodne puryny lub deazapuryny przydatne do leczenia (między innymi) infekcji wirusowych
|
EP2491007B1
(en)
|
2009-10-23 |
2013-09-25 |
Boehringer Ingelheim International GmbH |
Inhibitors of the microsomal prostaglandin E2 synthase-1
|
AU2010334974A1
(en)
|
2009-12-22 |
2012-07-12 |
Novartis Ag |
Tetravalent CD47-antibody constant region fusion protein for use in therapy
|
HUE031778T2
(en)
|
2010-05-14 |
2017-07-28 |
Univ Leland Stanford Junior |
Humanized and chimeric monoclonal antibodies against CD47
|
US9089520B2
(en)
|
2010-05-21 |
2015-07-28 |
Baylor College Of Medicine |
Methods for inducing selective apoptosis
|
US8759537B2
(en)
|
2010-08-20 |
2014-06-24 |
Boehringer Ingelheim International Gmbh |
3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents
|
US8586604B2
(en)
|
2010-08-20 |
2013-11-19 |
Boehringer Ingelheim International Gmbh |
Inhibitors of the microsomal prostaglandin E2 synthase-1
|
SG10201506703VA
(en)
|
2010-08-27 |
2015-10-29 |
Gilead Biologics Inc |
Antibodies To Matrix Metalloproteinase 9
|
WO2012045090A2
(en)
|
2010-10-01 |
2012-04-05 |
Ventirx Pharmaceuticals, Inc. |
Therapeutic use of a tlr agonist and combination therapy
|
CA2812787A1
(en)
|
2010-10-01 |
2012-04-05 |
Robert Hershberg |
Methods for the treatment of allergic diseases
|
TR201820015T4
(tr)
|
2010-12-09 |
2019-01-21 |
Univ Pennsylvania |
Kanser Tedavisi İçin Kimerik Antijen Reseptörü-Modifiye Edilmiş T Hücrelerinin Kullanılması
|
UY33779A
(es)
|
2010-12-10 |
2012-07-31 |
Boehringer Ingelheim Int |
?2-(fenilamino)-1H-bencimidazol-5-carboxamidas novedosas?
|
US8466186B2
(en)
|
2010-12-10 |
2013-06-18 |
Boehringer Ingelheim International Gmbh |
Compounds
|
US9096532B2
(en)
|
2010-12-13 |
2015-08-04 |
The Regents Of The University Of California |
Pyrazole inhibitors of COX-2 and sEH
|
AR084174A1
(es)
|
2010-12-21 |
2013-04-24 |
Lilly Co Eli |
Compuestos de imidazol-2-benzamida utiles para el tratamiento de osteoartritis y una composicion farmaceutica
|
DK2663550T3
(en)
|
2011-01-12 |
2017-03-27 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINS AS MODULATORS OF TOLL-LIKE RECEPTORS
|
PL2663555T4
(pl)
|
2011-01-12 |
2017-08-31 |
Ventirx Pharmaceuticals, Inc. |
Podstawione benzoazepiny jako modulatory receptora toll-podobnego
|
WO2012110860A1
(en)
|
2011-02-17 |
2012-08-23 |
Glenmark Pharmaceuticals S.A. |
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
CA2832685C
(en)
|
2011-04-08 |
2020-09-01 |
Janssen R&D Ireland |
Pyrimidine derivatives for the treatment of viral infections
|
NO2709989T3
(es)
|
2011-05-18 |
2018-05-19 |
|
|
AR086254A1
(es)
|
2011-05-26 |
2013-11-27 |
Lilly Co Eli |
Derivados de imidazol utiles para el tratamiento de artritis
|
WO2012170250A1
(en)
|
2011-06-07 |
2012-12-13 |
Radiation Control Technologies, Inc. |
Morpholino oligonucleotides capable of inhibiting cd47-mediated cellular damage and uses thereof
|
RU2632908C2
(ru)
|
2011-08-18 |
2017-10-11 |
Ниппон Синяку Ко., Лтд. |
Гетероциклическое производное и фармацевтическое средство
|
US9550835B2
(en)
|
2011-08-23 |
2017-01-24 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-DDR1 antibody having anti-tumor activity
|
GB201115529D0
(en)
|
2011-09-08 |
2011-10-26 |
Imp Innovations Ltd |
Antibodies, uses and methods
|
AU2012318580A1
(en)
|
2011-10-04 |
2014-05-22 |
Gilead Calistoga Llc |
Novel quinoxaline inhibitors of PI3K
|
US20140242095A1
(en)
|
2011-10-19 |
2014-08-28 |
University Health Network |
Antibodies and antibody fragments targeting sirp-alpha and their use in treating hematologic cancers
|
WO2013072825A1
(en)
|
2011-11-16 |
2013-05-23 |
Glenmark Pharmaceuticals S.A. |
Phtalazinone derivatives as mpegs -1 inhibitors
|
BR112014015197A2
(pt)
|
2011-12-21 |
2017-06-13 |
Novira Therapeutics Inc |
agentes antivirais de hepatite b
|
PL2804617T3
(pl)
|
2012-01-17 |
2020-11-30 |
The Board Of Trustees Of The Leland Stanford Junior University |
Reagenty sirp-alfa o wysokim powinowactwie
|
UY34573A
(es)
|
2012-01-27 |
2013-06-28 |
Gilead Sciences Inc |
Inhibidor de la quinasa que regula la señal de la apoptosis
|
WO2013116562A1
(en)
|
2012-02-03 |
2013-08-08 |
Gilead Calistoga Llc |
Compositions and methods of treating a disease with (s)-4 amino-6-((1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile
|
SG10201700160RA
(en)
|
2012-02-06 |
2017-03-30 |
Inhibrx Lp |
Cd47 antibodies and methods of use thereof
|
US20140140989A1
(en)
|
2012-02-06 |
2014-05-22 |
Inhibrx Llc |
Non-Platelet Depleting and Non-Red Blood Cell Depleting CD47 Antibodies and Methods of Use Thereof
|
JP6283320B2
(ja)
|
2012-02-08 |
2018-02-21 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
ウイルス感染の治療のためのピペリジノ−ピリミジン誘導体
|
AR089939A1
(es)
|
2012-02-09 |
2014-10-01 |
Glenmark Pharmaceuticals Sa |
COMPUESTOS BICICLICOS COMO INHIBIDORES DE mPGES-1
|
WO2013153535A1
(en)
|
2012-04-13 |
2013-10-17 |
Glenmark Pharmaceuticals S.A. |
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
TWI568722B
(zh)
|
2012-06-15 |
2017-02-01 |
葛蘭馬克製藥公司 |
作爲mPGES-1抑制劑之三唑酮化合物
|
MY183534A
(en)
|
2012-08-10 |
2021-02-25 |
Janssen Sciences Ireland Uc |
Alkylpyrimidine derivatives for the treatment of viral infections and further diseases
|
TW201427995A
(zh)
|
2012-09-24 |
2014-07-16 |
Gilead Sciences Inc |
抗ddr1抗體
|
KR102280595B1
(ko)
|
2012-10-10 |
2021-07-22 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
바이러스 감염 및 다른 질환 치료를 위한 피롤로[3,2-d]피리미딘 유도체
|
CN105142621A
(zh)
|
2012-10-24 |
2015-12-09 |
国家健康科学研究所 |
用于预防或治疗糖尿病和促进β-细胞存活的TPL2激酶抑制剂
|
CN105051018B
(zh)
|
2012-11-16 |
2019-09-20 |
爱尔兰詹森科学公司 |
用于治疗病毒性感染的杂环的经取代的2-氨基-喹唑啉衍生物
|
CN105121467B
(zh)
|
2012-12-03 |
2019-07-05 |
诺夫免疫股份有限公司 |
抗cd47抗体及其使用方法
|
EP2931751B1
(en)
|
2012-12-12 |
2020-02-05 |
Arch Oncology, Inc. |
Therapeutic cd47 antibodies
|
EP4116331A1
(en)
|
2012-12-17 |
2023-01-11 |
PF Argentum IP Holdings LLC |
Treatment of cd47+ disease cells with sirp alpha-fc fusions
|
US9018221B2
(en)
|
2012-12-21 |
2015-04-28 |
Gilead Calistoga, Llc |
Phosphatidylinositol 3-kinase inhibitors
|
TW201437203A
(zh)
|
2012-12-21 |
2014-10-01 |
Gilead Calistoga Llc |
磷脂醯肌醇3-激酶之抑制劑
|
EP3922643A1
(en)
|
2013-01-07 |
2021-12-15 |
Omniox, Inc. |
Polymeric forms of h-nox proteins
|
DK2958900T3
(da)
|
2013-02-21 |
2019-07-01 |
Janssen Sciences Ireland Unlimited Co |
2-aminopyrimidinderivater til behandling af virusinfektioner
|
WO2014165128A2
(en)
|
2013-03-12 |
2014-10-09 |
Novira Therapeutics, Inc. |
Hepatitis b antiviral agents
|
CA2903773A1
(en)
|
2013-03-15 |
2014-09-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for achieving therapeutically effective doses of anti-cd47 agents
|
WO2014167444A1
(en)
|
2013-04-08 |
2014-10-16 |
Glenmark Pharmaceuticals S.A. |
SUBSTITUTED BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
CN105308034B
(zh)
|
2013-06-14 |
2017-10-31 |
吉利德科学公司 |
磷脂酰肌醇3‑激酶抑制剂
|
WO2015059618A1
(en)
|
2013-10-22 |
2015-04-30 |
Glenmark Pharmaceuticals S.A. |
SUBSTITUTED PYRIMIDINE COMPOUNDS AS mPGES-1 INHIBITORS
|
US9290505B2
(en)
|
2013-12-23 |
2016-03-22 |
Gilead Sciences, Inc. |
Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
|
AU2015229448B2
(en)
|
2014-03-11 |
2020-09-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Anti SIRP-alpha antibodies and Bi-specific Macrophage Enhancing antibodies
|
ES2871027T3
(es)
|
2014-03-27 |
2021-10-28 |
Eicosis Llc |
Inhibidores potentes de la epóxido hidrolasa soluble
|
MX2016013144A
(es)
|
2014-04-10 |
2017-04-27 |
Seattle Children's Hospital (Dba Seattle Children's Res Institute) |
Metodo y composiciones para inmunoterapia celular.
|
RU2681537C2
(ru)
|
2014-04-14 |
2019-03-07 |
Шанхай Хэнжуй Фармасьютикал Ко., Лтд. |
Амидные производные и их фармацевтически приемлемые соли, способ их получения и медицинское применение
|
CN106535914B
(zh)
|
2014-08-08 |
2021-08-27 |
Alx 肿瘤生物技术公司 |
SIRP-α变体构建体及其用途
|
EP4321171A3
(en)
|
2014-08-08 |
2024-05-15 |
The Board of Trustees of the Leland Stanford Junior University |
Sirp alpha-antibody fusion proteins
|
LT3180363T
(lt)
|
2014-08-15 |
2019-11-25 |
Merck Patent Gmbh |
Sirp-alfa imunoglobulino sulieti baltymai
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
JO3474B1
(ar)
|
2014-08-29 |
2020-07-05 |
Amgen Inc |
مشتقات تيتراهيدرونافثالين التي تثبط بروتين mcl-1
|
AR102361A1
(es)
|
2014-10-29 |
2017-02-22 |
Lilly Co Eli |
Compuestos de metil-quinolina útiles para inhibir la sintasa-1 de prostaglandina microsomal e2
|
JO3581B1
(ar)
|
2014-10-29 |
2020-07-05 |
Lilly Co Eli |
مركبات ميثيل-بيبيريدين جديدة مفيدة لتثبيط إنزيم سينثاز -1 بروستاجلاندين e2 ميكروسومي
|
SG11201704058TA
(en)
|
2014-11-18 |
2017-06-29 |
Janssen Pharmaceutica Nv |
Cd47 antibodies, methods, and uses
|
EP3766895A1
(en)
|
2014-12-03 |
2021-01-20 |
Juno Therapeutics, Inc. |
Methods and compositions for adoptive cell therapy
|
EP3227337A1
(en)
|
2014-12-05 |
2017-10-11 |
F. Hoffmann-La Roche AG |
Methods and compositions for treating cancer using pd-1 axis antagonists and hpk1 antagonists
|
WO2016100236A2
(en)
|
2014-12-15 |
2016-06-23 |
Bellicum Pharmaceuticals, Inc. |
Methods for controlled elimination of therapeutic cells
|
BR112017014258A2
(pt)
|
2014-12-30 |
2018-03-06 |
Celgene Corp |
anticorpos anti-cd47 e usos dos mesmos
|
CN107921121B
(zh)
|
2015-03-04 |
2022-02-08 |
索伦托药业有限公司 |
结合cd47的抗体治疗剂
|
US20180243364A1
(en)
|
2015-03-17 |
2018-08-30 |
Omniox, Inc. |
Modulation of tumor immunity by protein-mediated 02 delivery
|
US10358472B2
(en)
|
2015-05-06 |
2019-07-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
High affinity CD47 analogs
|
CN115109158A
(zh)
|
2015-05-07 |
2022-09-27 |
阿吉纳斯公司 |
抗ox40抗体及其使用方法
|
CN104804093A
(zh)
|
2015-05-27 |
2015-07-29 |
江苏春申堂药业有限公司 |
一种针对cd47的单域抗体
|
CA2986060A1
(en)
|
2015-05-29 |
2016-12-08 |
Valerie Odegard |
Composition and methods for regulating inhibitory interactions in genetically engineered cells
|
US10618976B2
(en)
|
2015-06-16 |
2020-04-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
SIRP-α agonist antibody
|
IL283353B
(en)
|
2015-06-25 |
2022-09-01 |
Univ Health Network |
hpk1 inhibitors and methods of using them
|
NZ738950A
(en)
|
2015-08-07 |
2023-03-31 |
Alx Oncology Inc |
Constructs having a sirp-alpha domain or variant thereof
|
CA2999070A1
(en)
|
2015-09-17 |
2017-03-23 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
WO2017049251A2
(en)
|
2015-09-18 |
2017-03-23 |
Tioma Therapeutics, Inc. |
Therapeutic cd47 antibodies
|
EP3353209B1
(en)
|
2015-09-21 |
2022-03-16 |
Erasmus University Medical Center Rotterdam |
Anti-cd47 antibodies and methods of use
|
JP7089470B2
(ja)
|
2015-12-02 |
2022-06-22 |
アジェナス インコーポレイテッド |
抗体およびその使用方法
|
WO2017096276A1
(en)
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Anti-gitr antibodies and methods of use thereof
|
EP3383431A4
(en)
|
2015-12-02 |
2019-08-28 |
Agenus Inc. |
ANTI-GITR ANTIBODIES AND METHOD OF USE THEREOF
|
MA43389A
(fr)
|
2015-12-02 |
2021-05-12 |
Agenus Inc |
Anticorps anti-ox40 et leurs procédés d'utilisation
|
US20200079862A1
(en)
|
2015-12-03 |
2020-03-12 |
Agenus Inc. |
Anti-ox40 antibodies and methods of use thereof
|
AU2016374497B2
(en)
|
2015-12-16 |
2022-03-10 |
The Walter And Eliza Hall Institute Of Medical Research |
Inhibition of cytokine-induced SH2 protein in NK cells
|
KR102472087B1
(ko)
|
2016-01-11 |
2022-11-29 |
포티 세븐, 인코포레이티드 |
인간화된, 마우스 또는 키메라 항-cd47 단클론 항체
|
WO2017147410A1
(en)
|
2016-02-25 |
2017-08-31 |
Amgen Inc. |
Compounds that inhibit mcl-1 protein
|
US10858338B2
(en)
|
2016-03-15 |
2020-12-08 |
The Regents Of The University Of California |
Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH)
|
CN115785272A
(zh)
|
2016-04-14 |
2023-03-14 |
Ose免疫疗法 |
新型抗-SIRPa抗体及其治疗应用
|
CA3020373A1
(en)
|
2016-04-14 |
2017-10-19 |
Ose Immunotherapeutics |
New anti-sirpa antibodies and their therapeutic applications
|
JP2019511552A
(ja)
|
2016-04-15 |
2019-04-25 |
トリリウム セラピューティクス インコーポレイテッド |
Cd47遮断療法におけるマクロファージの刺激
|
WO2017196793A1
(en)
|
2016-05-09 |
2017-11-16 |
Celgene Corporation |
Cd47 antibodies and methods of use thereof
|
EP3243522A1
(en)
|
2016-05-10 |
2017-11-15 |
Université Pierre et Marie Curie (Paris 6) |
Agonist agents of cd47 inducing programmed cell death and their use in the treatments of diseases associated with defects in programmed cell death
|
US10858359B2
(en)
|
2016-06-07 |
2020-12-08 |
Jacobio Pharmaceuticals Co., Ltd. |
Heterocyclic ring derivatives useful as SHP2 inhibitors
|
CN106084052B
(zh)
|
2016-06-17 |
2019-12-27 |
长春金赛药业股份有限公司 |
抗cd47单克隆抗体及其应用
|
ES2800339T3
(es)
|
2016-06-30 |
2020-12-29 |
Gilead Sciences Inc |
4,6-diaminoquinazolinas como moduladores de cuna y métodos de uso de los mismos
|
AU2017307198B2
(en)
|
2016-08-03 |
2024-05-30 |
Forty Seven, Inc. |
Disrupting Fc receptor engagement on macrophages enhances efficacy of anti-SIRPalpha antibody therapy
|
WO2018049214A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer
|
AU2017322427B2
(en)
|
2016-09-09 |
2021-12-23 |
Incyte Corporation |
Pyrazolopyridine derivatives as HPK1 modulators and uses thereof for the treatment of cancer
|
AR109595A1
(es)
|
2016-09-09 |
2018-12-26 |
Incyte Corp |
Compuestos de pirazolopirimidina y usos de estos como inhibidores de hpk1
|
WO2018049191A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridone derivatives as hpk1 modulators and uses thereof for the treatment of cancer
|
US10111882B2
(en)
|
2016-09-14 |
2018-10-30 |
Gilead Sciences, Inc. |
SYK inhibitors
|
JOP20190009A1
(ar)
|
2016-09-21 |
2019-01-27 |
Alx Oncology Inc |
أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
|
WO2018075664A1
(en)
|
2016-10-18 |
2018-04-26 |
Regents Of The University Of Minnesota |
Tumor infiltrating lymphocytes and methods of therapy
|
CA2999058C
(en)
|
2016-10-20 |
2024-03-12 |
I-Mab |
Novel cd47 monoclonal antibodies and uses thereof
|
EP3529276A4
(en)
|
2016-10-21 |
2020-06-17 |
Arch Oncology, Inc. |
CD47 THERAPEUTIC ANTIBODIES
|
EP3538557A4
(en)
|
2016-11-08 |
2020-11-18 |
Ablexis, LLC |
ANTI-CD47 ANTIBODIES
|
CA3041340A1
(en)
|
2016-11-09 |
2018-05-17 |
Agenus Inc. |
Anti-ox40 antibodies, anti-gitr antibodies, and methods of use thereof
|
WO2018095428A1
(zh)
|
2016-11-28 |
2018-05-31 |
江苏恒瑞医药股份有限公司 |
Cd47抗体、其抗原结合片段及其医药用途
|
WO2018102366A1
(en)
|
2016-11-30 |
2018-06-07 |
Ariad Pharmaceuticals, Inc. |
Anilinopyrimidines as haematopoietic progenitor kinase 1 (hpk1) inhibitors
|
CN110325549B
(zh)
|
2016-12-09 |
2024-03-08 |
艾利妥 |
抗SIRPα抗体及其使用方法
|
KR102607101B1
(ko)
|
2017-01-26 |
2023-11-29 |
제트엘아이피 홀딩 리미티드 |
Cd47 항원 결합 유닛 및 그것의 사용
|
JP7132937B2
(ja)
|
2017-03-15 |
2022-09-07 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Hpk1の阻害剤としてのアザインドール
|
KR102317480B1
(ko)
|
2017-03-23 |
2021-10-25 |
자코바이오 파마슈티칼스 컴퍼니 리미티드 |
Shp2 억제제로서 유용한 신규한 헤테로환형 유도체
|
JP7129420B6
(ja)
|
2017-03-30 |
2024-02-02 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Hpk1阻害剤としてのイソキノリン
|
TW201904964A
(zh)
|
2017-03-30 |
2019-02-01 |
瑞士商赫孚孟拉羅股份公司 |
作為hpk1之抑制劑的啶
|
JP6453507B2
(ja)
|
2017-03-30 |
2019-01-16 |
アムジエン・インコーポレーテツド |
Mcl−1タンパク質を阻害する化合物
|
US10851164B2
(en)
|
2017-04-13 |
2020-12-01 |
Aduro Biotech Holdings, Europe B.V. |
Anti-SIRPα antibodies
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
WO2018210795A1
(en)
|
2017-05-16 |
2018-11-22 |
Synthon Biopharmaceuticals B.V. |
ANTI-SIRPα ANTIBODIES
|
CN109096395B
(zh)
|
2017-06-20 |
2022-06-24 |
华兰生物工程股份有限公司 |
阻断型cd47纳米抗体及其用途
|
KR20200019619A
(ko)
*
|
2017-06-21 |
2020-02-24 |
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 |
혈액성 악성종양에 대한 cd47 표적 요법을 위한 투약 파라미터
|
PL3658589T3
(pl)
|
2017-07-26 |
2024-03-18 |
Forty Seven, Inc. |
Przeciwciała anty-sirp-alfa i powiązane sposoby
|
JP7262440B2
(ja)
|
2017-08-02 |
2023-04-21 |
フェインズ セラピューティクス,インコーポレーテッド |
抗cd47抗体及びその使用
|
RU2020109544A
(ru)
|
2017-08-18 |
2021-09-20 |
Ультрахьюман Фор Лимитед |
Связывающие агенты
|
CN109422811A
(zh)
|
2017-08-29 |
2019-03-05 |
信达生物制药(苏州)有限公司 |
抗cd47抗体及其用途
|
CN108503708B
(zh)
|
2017-09-01 |
2021-07-30 |
北京智仁美博生物科技有限公司 |
抗人cd47抗体及其用途
|
CN109422726B
(zh)
|
2017-09-04 |
2022-10-28 |
华东理工大学 |
CD47/SIRPα的阻断剂及其应用
|
AU2018358004A1
(en)
|
2017-11-01 |
2020-05-28 |
Hummingbird Bioscience Pte. Ltd. |
CD47 antigen-binding molecules
|
WO2019103203A1
(ko)
|
2017-11-24 |
2019-05-31 |
주식회사 젬백스앤카엘 |
신규 펩티드 및 이를 포함한 조성물
|
MX2020005463A
(es)
|
2017-12-01 |
2020-09-07 |
Seattle Genetics Inc |
Anticuerpos anti grupo de diferenciacion 47 (anti-cd47) y sus usos para tratar cancer.
|
BR112020014202A2
(pt)
|
2018-01-12 |
2020-12-01 |
Aurigene Discovery Technologies Limited |
compostos de 1,2,4-oxadiazol como inibidores de vias de sinalização cd47
|
AU2019212674A1
(en)
|
2018-01-24 |
2020-09-03 |
Nanjing Legend Biotech Co., Ltd. |
Anti-CD47 antibodies that do not cause significant red blood cell agglutination
|
PE20210640A1
(es)
|
2018-02-13 |
2021-03-23 |
Gilead Sciences Inc |
Inhibidores pd-1/pd-l1
|
CN110144009B
(zh)
|
2018-02-14 |
2020-01-21 |
上海洛启生物医药技术有限公司 |
Cd47单域抗体及其用途
|
WO2019173692A2
(en)
|
2018-03-09 |
2019-09-12 |
Agenus Inc. |
Anti-cd73 antibodies and methods of use thereof
|
EP3765512A1
(en)
|
2018-03-13 |
2021-01-20 |
OSE Immunotherapeutics |
Use of anti-human sirpa v1 antibodies and method for producing anti-sirpa v1 antibodies
|
WO2019179366A1
(en)
|
2018-03-20 |
2019-09-26 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-cd47 antibodies
|
RU2020134294A
(ru)
|
2018-03-21 |
2022-04-22 |
ЭйЭлЭкс Онколоджи Инк. |
Антитела против сигнал-регуляторного белка альфа и способы их применения
|
CN110305212A
(zh)
|
2018-03-27 |
2019-10-08 |
信达生物制药(苏州)有限公司 |
抗cd47抗体及其用途
|
GB201804860D0
(en)
|
2018-03-27 |
2018-05-09 |
Ultrahuman Two Ltd |
CD47 Binding agents
|
CN110386984B
(zh)
|
2018-04-17 |
2022-04-22 |
杭州尚健生物技术有限公司 |
结合cd47蛋白的融合蛋白及其应用
|
WO2019213610A1
(en)
|
2018-05-03 |
2019-11-07 |
Board Of Regents, The University Of Texas System |
Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade
|
UA125163C2
(uk)
|
2018-05-14 |
2022-01-19 |
Гіліад Сайєнсіз, Інк. |
Інгібітори mcl-1
|
CN110577597B
(zh)
|
2018-06-11 |
2021-10-22 |
康诺亚生物医药科技(成都)有限公司 |
一种阻断CD47和SIRPα相互作用的抗体
|
CN112566662A
(zh)
|
2018-06-15 |
2021-03-26 |
阿库鲁斯生物科学公司 |
针对cd47的阻断抗体及其使用方法
|
CN112601544A
(zh)
|
2018-07-05 |
2021-04-02 |
三钰生物科技股份有限公司 |
人类抗cd47抗体及其用途
|
WO2020013170A1
(ja)
|
2018-07-10 |
2020-01-16 |
国立大学法人神戸大学 |
抗SIRPα抗体
|
UA126421C2
(uk)
|
2018-07-13 |
2022-09-28 |
Гіліад Сайєнсіз, Інк. |
Інгібітори pd-1/pd-l1
|
WO2020019135A1
(zh)
|
2018-07-23 |
2020-01-30 |
中国科学院微生物研究所 |
一种抗cd47抗体及其应用
|
WO2020036977A1
(en)
|
2018-08-13 |
2020-02-20 |
Arch Oncology, Inc. |
Therapeutic cd47 antibodies
|
TWI830774B
(zh)
|
2018-08-31 |
2024-02-01 |
大陸商南京聖和藥業股份有限公司 |
抗cd47抗體及其應用
|
MX2021003393A
(es)
|
2018-09-27 |
2021-05-13 |
Celgene Corp |
Proteinas de fijacion a sirp alfa y metodos de uso de estas.
|
JP7273172B2
(ja)
|
2018-10-31 |
2023-05-12 |
ギリアード サイエンシーズ, インコーポレイテッド |
Hpk1阻害活性を有する置換6-アザベンゾイミダゾール化合物
|
CR20210215A
(es)
|
2018-10-31 |
2021-06-17 |
Gilead Sciences Inc |
Compuestos de 6-azabencimidazol sustituidos como inhibidores de hpk1
|
ES2973832T3
(es)
|
2019-10-18 |
2024-06-24 |
Forty Seven Inc |
Terapias combinadas para el tratamiento de síndromes mielodisplásicos y leucemia mieloide aguda
|