ES2758679T3 - Composiciones que comprenden cepas bacterianas - Google Patents

Composiciones que comprenden cepas bacterianas Download PDF

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Publication number
ES2758679T3
ES2758679T3 ES16731641T ES16731641T ES2758679T3 ES 2758679 T3 ES2758679 T3 ES 2758679T3 ES 16731641 T ES16731641 T ES 16731641T ES 16731641 T ES16731641 T ES 16731641T ES 2758679 T3 ES2758679 T3 ES 2758679T3
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Spain
Prior art keywords
composition
asthma
compositions
treatment
day
Prior art date
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Active
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ES16731641T
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English (en)
Spanish (es)
Inventor
George Grant
Angela Margaret Patterson
Imke Mulder
Seanin Mccluskey
Emma Raftis
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4D Pharma Research Ltd
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4D Pharma Research Ltd
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Filing date
Publication date
Priority claimed from GBGB1510469.8A external-priority patent/GB201510469D0/en
Priority claimed from GBGB1520628.7A external-priority patent/GB201520628D0/en
Priority claimed from GBGB1604566.8A external-priority patent/GB201604566D0/en
Application filed by 4D Pharma Research Ltd filed Critical 4D Pharma Research Ltd
Application granted granted Critical
Publication of ES2758679T3 publication Critical patent/ES2758679T3/es
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/02—Nasal agents, e.g. decongestants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/314—Foods, ingredients or supplements having a functional effect on health having an effect on lung or respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
ES16731641T 2015-06-15 2016-06-15 Composiciones que comprenden cepas bacterianas Active ES2758679T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB1510469.8A GB201510469D0 (en) 2015-06-15 2015-06-15 Compostions comprising bacterial strains
GBGB1520628.7A GB201520628D0 (en) 2015-11-23 2015-11-23 Compositions comprising bacterial strains
GBGB1604566.8A GB201604566D0 (en) 2016-03-17 2016-03-17 Compositions comprising bacterial strains
PCT/GB2016/051773 WO2016203220A1 (en) 2015-06-15 2016-06-15 Compositions comprising bacterial strains

Publications (1)

Publication Number Publication Date
ES2758679T3 true ES2758679T3 (es) 2020-05-06

Family

ID=56194512

Family Applications (3)

Application Number Title Priority Date Filing Date
ES16731641T Active ES2758679T3 (es) 2015-06-15 2016-06-15 Composiciones que comprenden cepas bacterianas
ES19170925T Active ES2787523T3 (es) 2015-06-15 2016-06-15 Composiciones que comprenden cepas bacterianas
ES18167277T Active ES2863913T3 (es) 2015-06-15 2016-06-15 Composiciones que comprenden cepas bacterianas

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES19170925T Active ES2787523T3 (es) 2015-06-15 2016-06-15 Composiciones que comprenden cepas bacterianas
ES18167277T Active ES2863913T3 (es) 2015-06-15 2016-06-15 Composiciones que comprenden cepas bacterianas

Country Status (32)

Country Link
US (4) US10493112B2 (https=)
EP (4) EP3884953A1 (https=)
JP (2) JP6389950B2 (https=)
KR (1) KR20180012845A (https=)
CN (2) CN108738311B (https=)
AU (2) AU2016278069B2 (https=)
BR (1) BR112017025003A2 (https=)
CA (2) CA2988686C (https=)
CL (1) CL2017003191A1 (https=)
CO (1) CO2017013231A2 (https=)
CY (3) CY1122467T1 (https=)
DK (3) DK3204025T3 (https=)
EA (1) EA201890049A1 (https=)
ES (3) ES2758679T3 (https=)
HR (3) HRP20192057T1 (https=)
HU (3) HUE052737T2 (https=)
IL (1) IL255783B2 (https=)
LT (3) LT3204025T (https=)
MA (1) MA41060B1 (https=)
MD (3) MD3369425T2 (https=)
ME (2) ME03584B (https=)
MX (1) MX2017016564A (https=)
PE (1) PE20180266A1 (https=)
PL (3) PL3549592T3 (https=)
PT (3) PT3369425T (https=)
RS (3) RS61538B1 (https=)
SG (2) SG10201912322PA (https=)
SI (3) SI3204025T1 (https=)
SM (3) SMT201900665T1 (https=)
TW (2) TWI782682B (https=)
WO (1) WO2016203220A1 (https=)
ZA (1) ZA201707774B (https=)

Families Citing this family (46)

* Cited by examiner, ā€  Cited by third party
Publication number Priority date Publication date Assignee Title
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
EP3400953A1 (en) 2014-12-23 2018-11-14 4D Pharma Research Limited Pirin polypeptide and immune modulation
AR103260A1 (es) 2014-12-23 2017-04-26 4D Pharma Res Ltd ModulaciĆ³n inmunitaria
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactƩriennes
WO2016203221A1 (en) 2015-06-15 2016-12-22 4D Pharma Research Limited Compositions comprising bacterial strains
NZ737752A (en) 2015-06-15 2022-02-25 4D Pharma Res Ltd Compositions comprising bacterial strains
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactƩriennes
SMT201900588T1 (it) 2015-06-15 2019-11-13 4D Pharma Res Limited Blautia stercoris e wexlerae per uso nel trattamento di malattie infiammatorie ed autoimmuni
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
CN108513545B (zh) 2015-11-20 2020-11-03 4D制čÆē ”ē©¶ęœ‰é™å…¬åø 包含ē»†čŒčŒę Ŗēš„ē»„合ē‰©
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
ME03487B (me) 2016-03-04 2020-01-20 4D Pharma Plc Kompozicije koje sadrže blautia bakterijske sojeve za liječenje visceralne hipersenzitivnosti
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
CA3226196A1 (en) 2016-06-14 2017-12-21 Vedanta Biosciences, Inc. Treatment of clostridium difficile infection
US9999641B2 (en) 2016-06-14 2018-06-19 Vedanta Biosciences, Inc. Treatment of clostridium difficile infection
TWI802545B (zh) 2016-07-13 2023-05-21 č‹±å•†ļ¼”ļ¼¤č£½č—„ęœ‰é™å…¬åø 包含ē“°čŒčŒę Ŗ之ēµ„合ē‰©
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
EP3606325B1 (en) 2017-04-03 2024-09-04 Gusto Global, LLC Rational design of microbial-based biotherapeutics
DK3630136T3 (da) 2017-05-22 2021-05-25 4D Pharma Res Ltd SammensƦtninger, der omfatter bakteriestammer
EP3630942B1 (en) 2017-05-24 2022-11-30 4D Pharma Research Limited Compositions comprising bacterial strain
SMT202000695T1 (it) 2017-06-14 2021-01-05 4D Pharma Res Limited Composizioni comprendenti ceppi batterici
SMT202000555T1 (it) * 2017-06-14 2020-11-10 4D Pharma Res Limited Composizioni comprendenti un ceppo batterico del genere megaspaera e loro usi
GB201806779D0 (en) * 2018-04-25 2018-06-06 4D Pharma Res Ltd Compositions comprising bacterial strains
CA3066189A1 (en) * 2017-06-14 2018-12-20 4D Pharma Research Limited Compositions comprising bacterial strains
PL3743086T3 (pl) 2018-05-11 2022-06-20 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
AU2019321681A1 (en) 2018-08-17 2021-02-25 Vedanta Biosciences, Inc. Methods of decreasing dysbiosis and restoring a microbiome
TWI721549B (zh) * 2018-09-04 2021-03-11 ꘟ聚ę؊ē”Ÿē‰©ē§‘ęŠ€ęœ‰é™å…¬åø ꈈ갏å‰Æꓬę”æ菌ē”Øę–¼ę²»ē™‚ę…¢ę€§č…Žč‡Ÿē–¾ē—…之ē”Ø途
CN110917219B (zh) * 2018-09-04 2021-09-07 ꘟ聚ę؊ē”Ÿē‰©ē§‘ęŠ€ęœ‰é™å…¬åø ꈈ갏å‰ÆꋟꝆ菌ē”ØäŗŽåˆ¶å¤‡é¢„防和/ęˆ–ę²»ē–—ę…¢ę€§é˜»å”žę€§č‚ŗē—…ēš„医čÆē»„ęˆē‰©ēš„ē”Ø途
TWI688394B (zh) * 2018-09-04 2020-03-21 ꘟ聚ę؊ē”Ÿē‰©ē§‘ęŠ€ęœ‰é™å…¬åø ꈈ갏å‰Æꓬę”æ菌ē”Øę–¼é é˜²ęˆ–ę²»ē™‚ę…¢ę€§é˜»å”žę€§č‚ŗē—…之ē”Ø途
WO2020054728A1 (ja) * 2018-09-10 2020-03-19 国ē«‹ē ”ē©¶é–‹ē™ŗę³•äŗŗē†åŒ–å­¦ē ”ē©¶ę‰€ ļ¼°ļ½ļ½’ļ½ļ½ļ½’ļ½…ļ½–ļ½ļ½”ļ½…ļ½Œļ½Œļ½å±žć«å±žć™ć‚‹ē“°čŒć‚’ęœ‰åŠ¹ęˆåˆ†ćØć—ć¦å«ęœ‰ć™ć‚‹ć€ćƒˆćƒŖćƒ—ć‚·ćƒ³ę“»ę€§ć‚’ęŠ‘åˆ¶ć™ć‚‹ćŸć‚ć®ēµ„ęˆē‰©
WO2020055193A1 (en) * 2018-09-14 2020-03-19 Industry-Academic Cooperation Foundation, Yonsei University Microorganism with antibacterial activity for enteric pathogenic bacteria and pharmaceutical composition for preventing and treating enteric pathogenic bacteria induced disease using the same
AU2019351019B2 (en) * 2018-09-27 2024-09-19 Research Development Foundation Methods and probiotic compositions for the treatment of bone disorders
US11116803B2 (en) * 2018-10-31 2021-09-14 Multistars Biotechnology Company Limited Method of treating lung cancer using Parabacteroides goldsteinii
WO2020089488A1 (en) 2018-11-02 2020-05-07 4D Pharma Research Limited Compositions comprising bacterial strains
SG11202106258YA (en) * 2018-12-12 2021-07-29 4D Pharma Res Ltd Compositions comprising parabacteroides bacterial strains for treating cancer
CN110172427A (zh) * 2019-06-11 2019-08-27 ę±Ÿå—å¤§å­¦ äø€ē§ęé«˜ē‹„갏å‰Æę‹Ÿę†čŒå†»å¹²å­˜ę“»ēŽ‡ēš„ę–¹ę³•åŠåŗ”ē”Ø
JP7761556B2 (ja) * 2019-09-18 2025-10-28 ćƒŖć‚µćƒ¼ćƒ ćƒ‡ć‚£ćƒ™ćƒ­ćƒƒćƒ—ćƒ”ćƒ³ćƒˆ ćƒ•ć‚”ć‚¦ćƒ³ćƒ‡ćƒ¼ć‚·ćƒ§ćƒ³ ä»£č¬ę€§ē–¾ę‚£ćŠć‚ˆć³éšœå®³ć‚’ę²»ē™‚ć™ć‚‹ćŸć‚ć®ę–¹ę³•ćŠć‚ˆć³ćƒ—ćƒ­ćƒć‚¤ć‚Ŗćƒ†ć‚£ćƒƒć‚Æēµ„ęˆē‰©
WO2021221110A1 (ja) * 2020-04-29 2021-11-04 å­¦ę ”ę³•äŗŗꅶꇉē¾©å”¾ ļ¼“ļ½ˆļ¼‘ē“°čƒžåŠć³ļ¼åˆćÆļ¼“ļ½ˆļ¼‘ļ¼—ē“°čƒžć®å¢—ę®–åˆćÆę“»ę€§åŒ–ć‚’čŖ˜å°Žć™ć‚‹å°č…ø内ē“°čŒ
CN112410242A (zh) * 2020-08-25 2021-02-26 äøŠęµ·åø‚ē¬¬åäŗŗę°‘åŒ»é™¢ äø€ę Ŗ分ē¦»č‡Ŗē›“肠ē™Œč‚æē˜¤ē»„ē»‡ēš„ē‹„갏å‰ÆꋟꝆ菌ę Ŗ及其åŗ”ē”Ø
EP3967314A1 (en) * 2020-09-15 2022-03-16 Institut national de recherche pour l'agriculture l'alimentation et l'environnement Parabacteroides distasonis strains for use thereof in the treatment and prevention of gastrointestinal diseases and of disorders associated with gastrointestinal diseases
CN114908022A (zh) * 2022-06-17 2022-08-16 äø­å›½ęµ·ę“‹å¤§å­¦ äø€ē§å‰Æę‹Ÿę†čŒå±žčŒę ŖåŠå…¶åŸ¹å…»ę–¹ę³•å’Œåŗ”ē”Ø
AU2024327567A1 (en) * 2023-08-22 2026-01-08 Danisco Usa Inc. Methods and compositions for immune system regulation
CN120041316A (zh) * 2023-11-27 2025-05-27 ꅕꁩļ¼ˆå¹æ州ļ¼‰ē”Ÿē‰©ē§‘ęŠ€ęœ‰é™å…¬åø å‰Æę‹Ÿę†čŒå±žčŒę Ŗć€åŸ¹å…»ē‰©ć€čŒå‰‚及其åŗ”ē”Ø

Family Cites Families (361)

* Cited by examiner, ā€  Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
FR2613624B1 (fr) 1987-04-10 1990-11-23 Roussy Inst Gustave Composition pharmaceutique, administrable par voie orale, destinee a reduire les effets des b-lactamines
US5443826A (en) 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
DE68928665T2 (de) 1988-08-02 1998-11-12 Gastro Services Pty Ltd Behandlung von gastro-intestinalen krankheiten
KR100225087B1 (ko) 1990-03-23 1999-10-15 ķ•œģŠ¤ ė°œķ„°ė¼ė²¤ ķ”¼ķƒ€ģ•„ģ œģ˜ ģ‹ė¬¼ė‚“ ė°œķ˜„
DK0531372T4 (da) 1990-05-09 2004-08-09 Novozymes As CellulaseprƦparat omfattende et endoglucanaseenzym
GB9107305D0 (en) 1991-04-08 1991-05-22 Unilever Plc Probiotic
CA2100919A1 (en) 1992-07-20 1994-01-21 Takaharu Yamamoto Species-specific oligonucleotides for bifidobacteria and a method of detection using the same
JPH08504327A (ja) 1992-12-10 1996-05-14 ć‚®ć‚¹ćƒˆ ćƒ–ćƒ­ć‚«ćƒ‡ć‚¹ ćƒŠćƒ ćƒ­ćƒ¼ć‚¼ ćƒ•ć‚§ćƒ³ćƒŽćƒ¼ćƒˆć‚·ćƒ£ćƒƒćƒ— ē³øēŠ¶čŒć«ćŠć‘ć‚‹ē•°ēØ®ć‚æćƒ³ćƒ‘ć‚Æ恮ē”Ÿē”£
US5741665A (en) 1994-05-10 1998-04-21 University Of Hawaii Light-regulated promoters for production of heterologous proteins in filamentous fungi
US5599795A (en) 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
AUPM823094A0 (en) 1994-09-16 1994-10-13 Goodman Fielder Limited Probiotic compositions
AUPM864894A0 (en) 1994-10-07 1994-11-03 Borody, Thomas Julius Treatment of bowel-dependent neurological disorders
RU2078815C1 (ru) 1995-01-17 1997-05-10 ŠœŠ¾ŃŠŗŠ¾Š²ŃŠŗŠøŠ¹ Š½Š°ŃƒŃ‡Š½Š¾-ŠøссŠ»ŠµŠ“Š¾Š²Š°Ń‚ŠµŠ»ŃŒŃŠŗŠøŠ¹ ŠøŠ½ŃŃ‚Šøтут эŠæŠøŠ“ŠµŠ¼ŠøŠ¾Š»Š¾Š³ŠøŠø Šø Š¼ŠøŠŗрŠ¾Š±ŠøŠ¾Š»Š¾Š³ŠøŠø ŠøŠ¼.Š“.Š.Š“Š°Š±Ń€ŠøчŠµŠ²ŃŠŗŠ¾Š³Š¾ ŠØтŠ°Š¼Š¼ Š±Š°ŠŗтŠµŃ€ŠøŠ¹ bifidobacterium breve, ŠøсŠæŠ¾Š»ŃŒŠ·ŃƒŠµŠ¼Ń‹Š¹ Š“Š»Ń ŠæŠ¾Š»ŃƒŃ‡ŠµŠ½Šøя Š±Š°ŠŗтŠµŃ€ŠøŠ¹Š½Ń‹Ń… Š»ŠµŃ‡ŠµŠ±Š½Š¾-ŠæрŠ¾Ń„ŠøŠ»Š°ŠŗтŠøчŠµŃŠŗŠøх Š±ŠøфŠøŠ“Š¾ŃŠ¾Š“ŠµŃ€Š¶Š°Ń‰Šøх ŠæрŠµŠæŠ°Ń€Š°Ń‚Š¾Š²
JPH08259450A (ja) 1995-03-17 1996-10-08 Nichinichi Seiyaku Kk ć‚¤ćƒ³ć‚æćƒ¼ćƒ•ć‚§ćƒ­ćƒ³ē”£ē”Ÿå¢—強剤
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
AUPN698495A0 (en) 1995-12-06 1996-01-04 Pharma Pacific Pty Ltd Improved therapeutic formulation and method
SE508045C2 (sv) 1996-02-26 1998-08-17 Arla Ekonomisk Foerening Adhesionsinhibitorer, preparat innehƄllande desamma och fƶrfarande fƶr framstƤllning dƤrav
AUPN881396A0 (en) 1996-03-20 1996-04-18 Arnott's Biscuits Limited Enhancement of microbial colonization of the gastrointestinal tract
ATE407700T1 (de) 1996-03-20 2008-09-15 Univ New South Wales VerƤnderung der mikrobenflora im verdauungstrakt
JP4263241B2 (ja) 1996-03-27 2009-05-13 ćƒŽćƒœć‚¶ć‚¤ćƒ ć‚¹ ć‚¢ć‚Æćƒ†ć‚£ćƒ¼ć‚¼ćƒ«ć‚¹ć‚«ćƒ– ć‚¢ćƒ«ć‚«ćƒŖćƒ—ćƒ­ćƒ†ć‚¢ćƒ¼ć‚¼ć‚’ę¬ å¤±ć—ćŸē³øēŠ¶ēœŸčŒ
US6033864A (en) 1996-04-12 2000-03-07 The Regents Of The University Of California Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens
AU6773598A (en) 1997-03-26 1998-10-20 Institut Pasteur Treatment of gastrointestinal disease with ppar modulators
SE511524C2 (sv) 1997-06-02 1999-10-11 Essum Ab Lactobacillus casei rhamnosus-stam samt farmaceutisk beredning fƶr bekƤmpning av patogena tarmbakterier
US5925657A (en) 1997-06-18 1999-07-20 The General Hospital Corporation Use of PPARĪ³ agonists for inhibition of inflammatory cytokine production
AUPO758297A0 (en) 1997-06-27 1997-07-24 Rowe, James Baber Control of acidic gut syndrome
US5951977A (en) 1997-10-14 1999-09-14 The United States Of America, As Represented By The Secretary Of Agriculture Competitive exclusion culture for swine
IT1298918B1 (it) 1998-02-20 2000-02-07 Mendes Srl Uso di batteri dotati di arginina deiminasi per indurre apoptosi e/o ridurre una reazione infiammatoria e composizioni farmaceutiche
DE19826928A1 (de) 1998-06-17 1999-12-23 Novartis Consumer Health Gmbh Arzneimittel, lebensfƤhige anaerobe Bakterien enthaltend, die die Sulfatreduktion sulfatreduzierender Bakterien hemmen
ID29150A (id) 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
US7090973B1 (en) 1999-04-09 2006-08-15 Oscient Pharmaceuticals Corporation Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics
US6417212B1 (en) 1999-08-27 2002-07-09 Eli Lilly & Company Modulators of peroxisome proliferator activated receptors
CA2395266C (en) 2000-02-08 2009-04-14 F. Hoffmann-La Roche Ag Use of acid-stable subtilisin proteases in animal feed
FR2808689B1 (fr) 2000-05-11 2004-09-03 Agronomique Inst Nat Rech Utilisation de souches acetogenes hydrogenotrophes pour la prevention ou le traitement de troubles digestifs
US20020013270A1 (en) 2000-06-05 2002-01-31 Bolte Ellen R. Method for treating a mental disorder
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
WO2002042328A2 (en) 2000-11-27 2002-05-30 Washington University Method for studying the effects of commensal microflora on mammalian intestine and treatments of gastrointestinal-associated disease based thereon
DE10101793A1 (de) 2001-01-17 2002-08-01 Manfred Nilius Verwendung von SLPI zur Behandlung chronisch-entzĆ¼ndlicher Darmerkrankungen
EP1227152A1 (en) 2001-01-30 2002-07-31 SociƩtƩ des Produits NestlƩ S.A. Bacterial strain and genome of bifidobacterium
KR100437497B1 (ko) 2001-03-07 2004-06-25 ģ£¼ģ‹ķšŒģ‚¬ ķ”„ė”œė°”ģ“ģ˜¤ė‹‰ ė”œķƒ€ė°”ģ“ėŸ¬ģŠ¤ ė° ģœ ķ•“ ėÆøģƒė¬¼ ģ–µģ œ ķ™œģ„±ģ„ ź°€ģ§€ėŠ” ģ‹ ź·œė‚“ģ‚°ģ„± ė½ķ† ė°”ģ‹¤ėŸ¬ģŠ¤ ė£Øķ…Œė¦¬ ķ”„ė”œė°”ģ“ģ˜¤-16 ė° ģ“ė„¼ķ•Øģœ ķ•˜ėŠ” ģƒź· ķ™œģ„±ģ œ
EP1243273A1 (en) 2001-03-22 2002-09-25 Societe Des Produits Nestle S.A. Composition comprising a prebiotic for decreasing infammatory process and abnormal activation of non-specific immune parameters
EP1379552B2 (en) 2001-04-20 2014-11-19 The Institute for Systems Biology Toll-like receptor 5 ligands and methods of use
EP1260227A1 (en) 2001-05-23 2002-11-27 Societe Des Produits Nestle S.A. Lipoteichoic acid from lactic acid bacteria and its use to modulate immune responses mediated by gram-negative bacteria, potential pathogenic gram-positive bacteria
US20030092163A1 (en) 2001-07-26 2003-05-15 Collins John Kevin Probiotic bifidobacterium strains
MXPA04001999A (es) 2001-09-05 2004-07-16 Vsl Pharmaceuticals Inc Bacterias de acido lactico que comprende dinucleotidos de citosina-guanina no metilados para usarse en terapia.
GB0127916D0 (en) 2001-11-21 2002-01-16 Rowett Res Inst Method
EP1529054A4 (en) 2001-11-27 2005-12-28 Univ Washington THERAPEUTIC PROTEIN AND TREATMENTS
DK2224012T3 (da) 2001-12-17 2013-05-13 Corixa Corp SammensƦtninger og fremgangsmƄder til terapi og diagnose af inflammatoriske tarmsygdomme
US7101565B2 (en) 2002-02-05 2006-09-05 Corpak Medsystems, Inc. Probiotic/prebiotic composition and delivery method
DE10206995B4 (de) 2002-02-19 2014-01-02 Orthomol Pharmazeutische Vertriebs Gmbh MikronƤhrstoffkombinationsprodukt mit Pro- und Prebiotika
JP2003261453A (ja) 2002-03-11 2003-09-16 Nippon Berumu Kk ļ¼„ļ¼Žćƒ•ć‚§ć‚«ćƒŖć‚¹ć‹ć‚‰ćŖ悋ꊗ腫ē˜å‰¤åŠć³ę”¾å°„ē·šé˜²č­·å‰¤
DK1565547T4 (da) 2002-06-28 2013-01-14 Biosearch S A Probiotiske stammer, en fremgangsmƄde til selektion deraf, prƦparater deraf samt anvendelse deraf
US20040005304A1 (en) 2002-07-08 2004-01-08 Mak Wood, Inc. Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions
GB0307026D0 (en) 2003-03-27 2003-04-30 Rowett Res Inst Bacterial supplement
EP1481681A1 (en) 2003-05-30 2004-12-01 Claudio De Simone Lactic acid bacteria combination and compositions thereof
GB0316915D0 (en) 2003-07-18 2003-08-20 Glaxo Group Ltd Compounds
AU2003247193A1 (en) 2003-07-23 2005-02-04 M.D.Lab Corp. Acid tolerant probiotic lactobacillus plantarum probio-38 that can suppress the growth of pathogenic microorganism and tge coronavirus
US7485325B2 (en) 2003-08-06 2009-02-03 Gayle Dorothy Swain Animal food supplement compositions and methods of use
JP4683881B2 (ja) 2003-08-27 2011-05-18 ęœ‰é™ä¼šē¤¾ć‚¢ćƒ¼ć‚Æꊀē ” ꊗ腫ē˜ę“»ę€§å‰¤
US8192733B2 (en) 2003-08-29 2012-06-05 Cobb & Associates Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
US20050163764A1 (en) 2003-09-22 2005-07-28 Yale University Treatment with agonists of toll-like receptors
GB0323039D0 (en) 2003-10-01 2003-11-05 Danisco Method
PL1675481T3 (pl) 2003-10-24 2009-03-31 Nutricia Nv Kompozycja synbiotyczna dla niemowląt
US20050239706A1 (en) 2003-10-31 2005-10-27 Washington University In St. Louis Modulation of fiaf and the gastrointestinal microbiota as a means to control energy storage in a subject
JP4850715B2 (ja) 2003-12-17 2012-01-11 ć‚Ø惌ļ¼Žćƒ–悤ļ¼Žćƒ»ćƒŒćƒ¼ćƒˆćƒŖć‚·ć‚¢ ä¹³é…øē”£ē”ŸčŒåŠć³č‚ŗę©Ÿčƒ½
ES2235642B2 (es) 2003-12-18 2006-03-01 Gat Formulation Gmbh Proceso de multi-microencapsulacion continuo para la mejora de la estabilidad y almacenamiento de ingredientes biologicamente activos.
EP1727894A1 (en) 2004-03-22 2006-12-06 Government of the United States of America as represented by The Secretary of the Department of Health and Human Services Cellular and viral inactivation
US20080248068A1 (en) 2004-05-07 2008-10-09 Hans-Gustaf Ljunggren Use of Flagellin as an Adjuvant for Vaccine
US7638513B2 (en) 2004-06-02 2009-12-29 Schering Corporation Compounds for the treatment of inflammatory disorders
PE20060426A1 (es) 2004-06-02 2006-06-28 Schering Corp DERIVADOS DE ACIDO TARTARICO COMO INHIBIDORES DE MMPs, ADAMs, TACE Y TNF-alfa
DK1765391T3 (da) 2004-06-07 2013-03-25 Qu Biolog Inc Bakterielle prƦparater til behandlingen af cancer
ATE361101T1 (de) 2004-08-24 2007-05-15 Nutricia Nv Nahrungszusammensetzung die unverdauliche oligosaccharide enthƤlt
US20060062773A1 (en) 2004-09-21 2006-03-23 The Procter & Gamble Company Compositions for maintaining and restoring normal gastrointestinal flora
KR100468522B1 (ko) 2004-10-12 2005-01-31 ģ£¼ģ‹ķšŒģ‚¬ ķ”„ė”œė°”ģ“ģ˜¤ė‹‰ ģ½”ė”œė‚˜ė°”ģ“ėŸ¬ģŠ¤ģ™€ ė¼ģ§€ ģØģ½”ė°”ģ“ėŸ¬ģŠ¤ 2ķ˜•ģ˜ ģƒģœ”ģ„ ģ–µģ œķ•˜ėŠ” ģ‹ ź·œķ•œ ė‚“ģ‚°ģ„± ķ”„ė”œė°”ģ“ģ˜¤ķ‹± ģ—”ķ…Œė”œģ½”ģ»¤ģŠ¤ķ›¼ģ‹œģ›€ ķ”„ė”œė°”ģ“ģ˜¤-63
US20060115465A1 (en) 2004-10-29 2006-06-01 Macfarlane George Treatment of gastrointestinal disorders
ITMI20042189A1 (it) 2004-11-16 2005-02-16 Anidral Srl Composizione a base di batteri probiotici e suo uso nella prevenzione e-o nel trattamento di patologie e-o infezioni respiratorie e nel miglioramento della funzionalita' intestinale
EP2351492B1 (en) 2005-02-28 2014-08-20 N.V. Nutricia Nutritional composition with probiotics
US20090233888A1 (en) 2005-03-23 2009-09-17 Usc Stevens, University Of Southern California Treatment of disease conditions through modulation of hydrogen sulfide produced by small intestinal bacterial overgrowth
EP1861490A4 (en) 2005-03-23 2010-11-17 Univ St Louis USE OF ARCHAEA FOR MODULATING NUTRITIONAL FUNCTIONALITY OF GASTROINTESTINAL BIOZOOSIS
JP2006265212A (ja) 2005-03-25 2006-10-05 Institute Of Physical & Chemical Research ļ¼©ļ½Œāˆ’ļ¼’ļ¼‘ē”£ē”ŸčŖ˜å°Žå‰¤
US20100233312A9 (en) 2005-04-11 2010-09-16 The Procter & Gamble Company Compositions comprising probiotic and sweetener components
EP1714660A1 (en) 2005-04-21 2006-10-25 N.V. Nutricia Uronic acid and probiotics
AU2006241262A1 (en) 2005-04-26 2006-11-02 Teagasc- The Agriculture And Food Development Authority Probiotic composition suitable for animals
US7572474B2 (en) 2005-06-01 2009-08-11 Mead Johnson Nutrition Company Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants
US8075934B2 (en) 2008-10-24 2011-12-13 Mead Johnson Nutrition Company Nutritional composition with improved digestibility
JP2007084533A (ja) 2005-08-24 2007-04-05 Prima Meat Packers Ltd 免ē–«åæœē­”čŖæēƀēµ„ęˆē‰©åŠć³č©²ēµ„ęˆē‰©ć‚’ęœ‰åŠ¹ęˆåˆ†ćØć™ć‚‹é£Ÿå“
US7625704B2 (en) 2005-08-31 2009-12-01 Fred Hutchinson Cancer Research Center Methods and compositions for identifying bacteria associated with bacteria vaginosis
US20080199460A1 (en) 2005-09-01 2008-08-21 Schering Corporation Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease
EP1945234B1 (en) 2005-09-23 2012-12-19 Gwangju Institute of Science and Technology Composition for preventing or treating arthritis comprising lactic acid bacteria and collangen as active ingredients
BRPI0616866A8 (pt) 2005-10-06 2018-07-31 Nestec Sa Enterococos probiĆ³ticos para melhorar a imunidade
EP1776877A1 (en) 2005-10-21 2007-04-25 N.V. Nutricia Method for stimulating the intestinal flora
RU2395218C2 (ru) 2005-10-24 2010-07-27 ŠŠµŃŃ‚ŠµŠŗ Š”.Š. ŠšŠ¾Š¼ŠæŠ¾Š·ŠøцŠøя ŠæŠøщŠµŠ²Ń‹Ń… Š²Š¾Š»Š¾ŠŗŠ¾Š½ Š“Š»Ń ŠæрŠ¾Ń„ŠøŠ»Š°ŠŗтŠøŠŗŠø ŠøŠ»Šø Š»ŠµŃ‡ŠµŠ½Šøя Š·Š°Š±Š¾Š»ŠµŠ²Š°Š½ŠøŠ¹ ŠæŠøщŠµŠ²Š°Ń€ŠøтŠµŠ»ŃŒŠ½Š¾Š¹ сŠøстŠµŠ¼Ń‹ Šø ŠŗŠ¾Š¼ŠæŠ¾Š·ŠøцŠøя ŠæŠøщŠµŠ²Ń‹Ń… Š²Š¾Š»Š¾ŠŗŠ¾Š½, эффŠµŠŗтŠøŠ²Š½Š°Ń ŠæрŠø Š»ŠµŃ‡ŠµŠ½ŠøŠø хŠ¾Š»ŠµŃ€Ń‹
JP2007116991A (ja) 2005-10-28 2007-05-17 Eternal Light General Institute Inc ę©Ÿčƒ½ę€§é£Ÿå“
US7767420B2 (en) 2005-11-03 2010-08-03 Momenta Pharmaceuticals, Inc. Heparan sulfate glycosaminoglycan lyase and uses thereof
KR20080070876A (ko) 2005-12-01 2008-07-31 ģ‰ė§ ģ½”ķ¬ė ˆģ“ģ…˜ ģ—¼ģ¦ ģ§ˆķ™˜ ė° ėÆøģƒė¬¼ ģ§ˆė³‘ ģ¹˜ė£Œģš© ģ”°ģ„±ė¬¼
WO2007098371A2 (en) 2006-02-16 2007-08-30 Wayne State University Use of flagellin to prevent and treat gram negative bacterial infection
US20080260906A1 (en) 2006-03-17 2008-10-23 Marko Stojanovic Compositions comprising probiotic and sweetener components
JP5031249B2 (ja) 2006-03-22 2012-09-19 å­¦ę ”ę³•äŗŗ北里ē ”ē©¶ę‰€ ē‚Žē—‡ęŠ‘制作ē”Øć®ć‚ć‚‹čŒä½“å«ęœ‰ēµ„ęˆē‰©
US20100316769A1 (en) 2006-03-29 2010-12-16 Gail Czarnecki-Maulden Dietary supplements containing probiotics
EP2040724B1 (en) 2006-05-18 2011-10-05 Biobalance Llc Biotherapeutic compositions comprising probiotic escherichia coli and metronidazole and uses thereof
MX2008015031A (es) 2006-05-26 2008-12-05 Nestec Sa Metodos de uso y composiciones nutritivas de extracto de touchi.
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
ES2525223T3 (es) 2006-08-04 2014-12-19 Shs International Ltd. FĆ³rmula sin proteĆ­nas
WO2008031438A2 (en) 2006-09-13 2008-03-20 Region Hovedstaden V/Gentofte Hospital Treatment of asthma, eczema and/or allergy using non-pathogenic organisms
US20080069861A1 (en) 2006-09-19 2008-03-20 National Starch And Chemical Investment Holding Corporation Probiotic/Non-Probiotic Combinations
CN101595133B (zh) 2006-10-27 2012-11-14 ęÆ”åˆ©ę—¶čƒ¶å›Šå…¬åø ē¾Ÿäø™åŸŗē”²åŸŗēŗ¤ē»“ē“ ē”¬čƒ¶å›ŠåŠåˆ¶å¤‡ę–¹ę³•
WO2008053444A2 (en) 2006-11-01 2008-05-08 The Procter & Gamble Company Treating a respiratory condition with bifidobacterium
PL1920781T3 (pl) 2006-11-10 2015-06-30 Glycotope Gmbh Kompozycje zawierające core-1-dodatnie mikroorganizmy i ich zastosowanie w leczeniu lub profilaktyce nowotworĆ³w
WO2008064489A1 (en) 2006-12-01 2008-06-05 Mcmaster University Probiotics to inhibit inflammation
EP2102350A4 (en) 2006-12-18 2012-08-08 Univ St Louis DARMMICROBIOMA AS A BIOMARKER AND THERAPEUTIC OBJECT FOR THE TREATMENT OF ADIPOSITAS OR ADIPOSITASCONDUCTIVE DISEASES
DE102006062250A1 (de) 2006-12-22 2008-06-26 Roland Saur-Brosch Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung fĆ¼r die Behandlung und Vorbeugung von abdominalen Beschwerden
WO2008083157A2 (en) 2006-12-29 2008-07-10 Washington University In St. Louis Altering pgc-1alapha, ampk, fiaf, or the gastrointestinal microbiota as a means to modulate body fat and/or weight loss in a subject
JP2008195635A (ja) 2007-02-09 2008-08-28 Crossfield Bio Inc 馬ē”Øä¹³é…øčŒč£½å‰¤
GB0703285D0 (en) * 2007-02-20 2007-03-28 Cutler Daniel Retractable covering apparatus
CN105796607A (zh) 2007-02-28 2016-07-27 Mjn ē¾Žå›½ęŽ§č‚”ęœ‰é™č“£ä»»å…¬åø ē”ØäŗŽå„æē«„ęˆ–å©“å¹¼å„æēš„å«ęœ‰ē­ę“»ē›Šē”ŸčŒēš„äŗ§å“
BRPI0809448A2 (pt) 2007-03-28 2014-09-09 Alimentary Health Ltd Cepas de bifidobacterium probiĆ³ticas
EP2134833B1 (en) 2007-03-28 2016-03-09 Alimentary Health Limited Probiotic bifidobacterium strain
AU2008245685B2 (en) 2007-04-24 2013-06-27 Kemin Industries, Inc. Broad-spectrum antibacterial and antifungal activity of Lactobacillus johnsonii D115
EP1997499A1 (en) 2007-05-31 2008-12-03 Puleva Biotech, S.A. Mammalian milk microorganisms, compositions containing them and their use for the treatment of mastitis
EP1997906A1 (en) 2007-06-01 2008-12-03 Friesland Brands B.V. Lactobacillus
EP1997907A1 (en) 2007-06-01 2008-12-03 Friesland Brands B.V. Bifidobacteria
EP1997905A1 (en) 2007-06-01 2008-12-03 Friesland Brands B.V. Nucleic acid amplification
WO2008153377A1 (en) 2007-06-15 2008-12-18 N.V. Nutricia Nutrition with non-viable bifidobacterium and non-digestible oligosaccharide
EP2522358B1 (en) 2007-06-27 2016-11-09 Laboratorios Ordesa, S.l. Peptides against rotavirus infection
US20110027348A1 (en) 2007-08-27 2011-02-03 Janos Feher Composition and method inhibiting inflammation
WO2009030254A1 (en) 2007-09-04 2009-03-12 Curevac Gmbh Complexes of rna and cationic peptides for transfection and for immunostimulation
EP2192909A2 (en) 2007-10-01 2010-06-09 University College Cork-National University of Ireland, Cork Modulation of tissue fatty acid composition of a host by human gut bacteria
US8658153B2 (en) 2007-10-20 2014-02-25 Universite De Liege Bifidobacterial species
EP2211879B1 (en) 2007-10-26 2014-05-07 Brenda E. Moore Probiotic compositions and methods for inducing and supporting weight loss
ES2567079T3 (es) 2007-11-02 2016-04-19 Momenta Pharmaceuticals, Inc. Composiciones de polisacƔridos que no son anticoagulantes
EP2065048A1 (en) 2007-11-30 2009-06-03 Institut Pasteur Use of a L. casei strain, for the preparation of a composition for inhibiting mast cell activation
CN101969966B (zh) 2007-12-07 2013-05-08 åŠŖē‰¹é‡ŒåøŒäŗšå…¬åø ē”ØäŗŽå°˜čžØå˜ę€ååŗ”ēš„åŒę­§ę†čŒ
WO2009079564A2 (en) 2007-12-17 2009-06-25 Emory University Immunogenic compositions and methods of use thereof
ES2343499B1 (es) 2007-12-24 2011-06-10 Consejo Superior De Investigaciones Cientificas Microorganismos para mejorar el estado de salud de individuos con desordenes relacionados con la ingesta de gluten.
US20090196921A1 (en) 2008-02-06 2009-08-06 The Procter & Gamble Company Compositions Methods and Kits For Enhancing Immune Response To A Respiratory Condition
EP2103226A1 (en) 2008-03-18 2009-09-23 Friesland Brands B.V. Long-life probiotic food product
AU2009236585B2 (en) 2008-04-18 2013-03-07 Vaxinnate Corporation Deletion mutants of flagellin and methods of use
JP2011520435A (ja) 2008-05-13 2011-07-21 悰ćƒŖć‚³ćƒˆćƒ¼ćƒ— ć‚²ćƒ¼ć‚Øćƒ ćƒ™ćƒ¼ćƒćƒ¼ ē™ŗé…µćƒ—ćƒ­ć‚»ć‚¹
MX2008006546A (es) 2008-05-21 2009-11-23 Sigma Alimentos Sa De Cv Bifidobacteria productora de Ć”cido fĆ³lico, composiciĆ³n alimenticia y uso de la bifidobacteria.
CN102940652B (zh) 2008-05-28 2015-03-25 青岛äøœęµ·čÆäøšęœ‰é™å…¬åø äø¤å½¢ēœŸę†čŒåˆ¶å‰‚及其åŗ”ē”Ø
CN101590081A (zh) 2008-05-28 2009-12-02 青岛äøœęµ·čÆäøšęœ‰é™å…¬åø å‡øč…¹ēœŸę†čŒå’Œäø¤å½¢ēœŸę†čŒåˆ¶å‰‚及其åŗ”ē”Ø
WO2009149149A1 (en) 2008-06-04 2009-12-10 Trustees Of Dartmouth College Prevention or treatment of immune-relevant disease by modification of microfloral populations
EP2133088A3 (en) 2008-06-09 2010-01-27 Nestec S.A. Rooibos and inflammation
WO2009151315A1 (en) 2008-06-13 2009-12-17 N.V. Nutricia Nutritional composition for infants delivered via caesarean section
WO2009154463A2 (en) 2008-06-20 2009-12-23 Stichting Top Institute Food And Nutrition Butyrate as a medicament to improve visceral perception in humans
EP2138186A1 (en) 2008-06-24 2009-12-30 Nestec S.A. Probiotics, secretory IgA and inflammation
WO2010002241A1 (en) 2008-06-30 2010-01-07 N.V. Nutricia Nutritional composition for infants delivered via caesarean section
KR101017448B1 (ko) 2008-09-18 2011-02-23 ģ£¼ģ‹ķšŒģ‚¬ķ•œźµ­ģ•¼ģæ ė„“ķŠø ėŒ€ģž„ģ˜ ź±“ź°• ģ¦ģ§„ ķšØėŠ„ģ„ ź°–ėŠ” ė¹„ķ”¼ė„ė°•ķ…Œė¦¬ģ›€ ė”±ź²€ ģ—ģ“ģ·Øģ™€ģ“8004 ė° ģ“ė„¼ ģœ ķšØģ„±ė¶„ģœ¼ė”œ ķ•Øģœ ķ•˜ėŠ” ģ œķ’ˆ
US20100074870A1 (en) 2008-09-19 2010-03-25 Bristol-Myers Squibb Company Probiotic infant products
US8137718B2 (en) 2008-09-19 2012-03-20 Mead Johnson Nutrition Company Probiotic infant products
KR101057357B1 (ko) 2008-09-22 2011-08-17 ź“‘ģ£¼ź³¼ķ•™źø°ģˆ ģ› ģœ ģ‚°ź·  ė° ģ½œė¼ź²ģ„ ģœ ķšØģ„±ė¶„ģœ¼ė”œ ķ¬ķ•Øķ•˜ėŠ” ź“€ģ ˆģ—¼ ģ˜ˆė°© ė˜ėŠ” ģ¹˜ė£Œģš© ģ•½ģ œķ•™ģ  ģ”°ģ„±ė¬¼ ė° ģ‹ķ’ˆ ģ”°ģ„±ė¬¼
US9603876B2 (en) 2008-09-25 2017-03-28 New York University Compositions and methods for restoring gastrointestinal microbiota following antibiotic treatment
WO2010037408A1 (en) 2008-09-30 2010-04-08 Curevac Gmbh Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
WO2010037402A1 (en) 2008-10-02 2010-04-08 Dako Denmark A/S Molecular vaccines for infectious disease
US20110223137A1 (en) 2008-12-05 2011-09-15 Nestec S.A. Compositions for use in low-birth weight infants
EP2378890B1 (en) 2008-12-19 2014-10-01 Nestec S.A. Prevention and treatment of rotavirus diarrhoea
IT1392672B1 (it) 2009-01-12 2012-03-16 Wyeth Consumer Healthcare S P A Composizioni comprendenti componenti probiotici e prebiotici e sali minerali, con lactoferrina
TWI541021B (zh) 2009-03-05 2016-07-11 č‰¾ä¼Æē¶­ęœ‰é™å…¬åø ļ¼©ļ½Œļ¼ļ¼‘ļ¼—ēµåˆč›‹ē™½
JP5710876B2 (ja) 2009-03-26 2015-04-30 ć‚Æćƒ­ć‚¹ćƒ•ć‚£ćƒ¼ćƒ«ćƒ‰ćƒć‚¤ć‚Ŗę Ŗ式会ē¤¾ ę–°č¦ćƒ“ćƒ•ć‚£ćƒ‰ćƒć‚Æ惆ćƒŖć‚¦ćƒ å±žå¾®ē”Ÿē‰©ćŠć‚ˆć³ćć®åˆ©ē”Ø
WO2010129707A1 (en) * 2009-05-05 2010-11-11 Amgen Inc. Etanercept in combination with glucocorticoids for use in treating psoriasis
EP2427499A1 (en) 2009-05-07 2012-03-14 Tate&Lyle Ingredients France SAS Compositions and methods for making alpha-(1,2)-branched alpha-(1,6) oligodextrans
US10576110B2 (en) 2009-05-11 2020-03-03 Societe Des Produits Nestle S.A. Lactobacillus johnsonii La1 NCC533 (CNCM I-1225) and immune disorders
EP2251020A1 (en) 2009-05-11 2010-11-17 Nestec S.A. Short-time high temperature treatment generates microbial preparations with anti-inflammatory profiles
EP2251022A1 (en) 2009-05-11 2010-11-17 Nestec S.A. Non-replicating micro-organisms and their immune boosting effect
KR20100128168A (ko) 2009-05-27 2010-12-07 ģ¤‘ģ•™ėŒ€ķ•™źµ ģ‚°ķ•™ķ˜‘ė „ė‹Ø ź³µģ•” ė¦¬ė†€ė ˆģ‚° ģƒģ‚°ėŠ„ģ“ ģš°ģˆ˜ķ•œ ģ‹ ź·œķ•œ ź· ģ£¼
US20100311686A1 (en) 2009-06-03 2010-12-09 Kasper Lloyd H Nutraceutical composition and methods for preventing or treating multiple sclerosis
WO2010143940A1 (en) 2009-06-12 2010-12-16 N.V. Nutricia Synergistic mixture of beta-galacto-oligosaccharides with beta-1,3 and beta-1,4/1,6 linkages
EP2443259A4 (en) 2009-06-16 2012-10-10 Univ Columbia BIOMARKERS ASSOCIATED WITH AUTISM AND USES THEREOF
WO2011005756A1 (en) 2009-07-06 2011-01-13 Puretech Ventures, Llc Delivery of agents targeted to microbiota niches
CA2768301A1 (en) 2009-07-24 2011-01-27 Southwest Regional Pcr, Llc Universal microbial diagnosis, detection, quantification, and specimen-targeted therapy
CN102905557A (zh) 2009-08-18 2013-01-30 雀巢äŗ§å“ęŠ€ęœÆę“åŠ©ęœ‰é™å…¬åø 包含é•æåŒę­§ę†čŒčŒę Ŗ并äø”ē‰¹åˆ«ę˜ÆåœØå©“å„æ和å„æē«„äø­å‡å°‘食ē‰©čæ‡ę•ē—‡ēŠ¶ēš„萄养ē»„合ē‰©
US20110053829A1 (en) 2009-09-03 2011-03-03 Curevac Gmbh Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
PL2480255T3 (pl) 2009-09-23 2018-07-31 Thomas Julius Borody Terapia przewlekłych zakażeń jelitowych
EP2308498A1 (en) 2009-09-30 2011-04-13 Nestec S.A. Administration of Bifidobacterium breve during infancy to prevent inflammation later in life
CA2776420A1 (en) 2009-10-05 2011-04-14 Aak Patent B.V. Methods for diagnosing irritable bowel syndrome
WO2011044208A1 (en) 2009-10-06 2011-04-14 Scott Dorfner Antibiotic formulations providing reduced gastrointentestinal side effects
EP2498789B1 (en) 2009-11-11 2016-06-22 Alimentary Health Limited Probiotic bifidobacterium strain
WO2011075138A1 (en) 2009-12-18 2011-06-23 Hill's Pet Nutrition, Inc. Pet food compositions including probiotics and methods of manufacture and use thereof
US20150104418A1 (en) 2014-12-18 2015-04-16 Microbios, Inc. Bacterial composition
FR2955774A1 (fr) 2010-02-02 2011-08-05 Aragan Preparation destinee a traiter l'exces ponderal et les desordres associes et applications de ladite preparation
NL2004200C2 (en) 2010-02-05 2011-08-08 Friesland Brands Bv Use of sialyl oligosaccharides in weight management.
NL2004201C2 (en) 2010-02-05 2011-08-08 Friesland Brands Bv Use of sialyl oligosaccharides to modulate the immune system.
IT1398553B1 (it) 2010-03-08 2013-03-01 Probiotical Spa Composizione comprendente batteri probiotici per il trattamento di patologie associate con le alterazioni del sistema immunitario.
JP5737646B2 (ja) 2010-03-24 2015-06-17 ę£®äø‹ä»äø¹ę Ŗ式会ē¤¾ ęŠ—ć‚¢ćƒ¬ćƒ«ć‚®ćƒ¼å‰¤
WO2011121379A1 (en) 2010-03-30 2011-10-06 Assistance Publique - Hopitaux De Paris Use of bifidobacteria for preventing allergy in breastfed infants
US8951512B2 (en) 2010-05-04 2015-02-10 New York University Methods for treating bone disorders by characterizing and restoring mammalian bacterial microbiota
WO2011149335A1 (en) 2010-05-25 2011-12-01 N.V. Nutricia Immune imprinting nutritional composition
WO2011153226A2 (en) 2010-06-01 2011-12-08 Moore Research Enterprises Llc Cellular constituents from bacteroides, compositions thereof, and therapeutic methods employing bacteroides or cellular constituents thereof
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国ē«‹å¤§å­¦ę³•äŗŗę±äŗ¬å¤§å­¦ åˆ¶å¾”ę€§ļ½”ē“°čƒžć®å¢—ę®–ć¾ćŸćÆ集ē©ć‚’čŖ˜å°Žć™ć‚‹ä½œē”Ø悒꜉恙悋ēµ„ęˆē‰©
TWI417054B (zh) 2010-06-15 2013-12-01 Jen Shine Biotechnology Co Ltd ꖰē©Žē³žč…øēƒčŒļ½Œļ½Šļ½“ļ¼ļ¼ļ¼‘及其ē›Šē”Ÿē”Ø途
EP2397145A1 (en) 2010-06-18 2011-12-21 Nestec S.A. L. johnsonii La1, B. longum NCC2705 and immune disorders
FR2962045B1 (fr) 2010-07-05 2012-08-17 Bifinove Complexe macromoleculaire d'origine bacterienne et utilisation dudit complexe moleculaire pour prevenir et traiter les rhumatismes inflammatoires
TWI401086B (zh) 2010-07-20 2013-07-11 Univ China Medical čƒščŠ½ä¹³é…øę”æčŒåŠå…¶ē”Ø途
SG187201A1 (en) 2010-07-26 2013-02-28 Qu Biolog Inc Immunogenic anti-inflammatory compositions
EP3424515A3 (en) 2010-08-04 2019-06-19 Thomas Julius Borody Stool collection devices and methods for using them
US9386793B2 (en) 2010-08-20 2016-07-12 New York University Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota
KR101250463B1 (ko) 2010-10-12 2013-04-15 ėŒ€ķ•œėƼźµ­ ģ‹ ģƒģ•„ ė¶„ė³€ģ—ģ„œ ė¶„ė¦¬ķ•œ ė‚“ģ‚°ģ†Œģ„± ė¹„ķ”¼ė„ė°•ķ…Œė¦¬ģ›€ ė”±ź²€ ė¹„ķ”¼ė”ģŠ¤ ģœ ģ‚°ź·  ė° ģ“ė„¼ ģ“ģš©ķ•œ ķ”„ė”œė°”ģ“ģ˜¤ķ‹± ģ”°ģ„±ė¬¼
KR20130113476A (ko) 2010-10-27 2013-10-15 ?ķ‹°ė°±ķŠø ģ—ģ“/ģ—ģŠ¤ ģøķ„°ģ¹¼ė ˆģ“ķ„° ļ¼ˆļ½‰ļ½Žļ½”ļ½…ļ½’ļ½ƒļ½ļ½Œļ½ļ½”ļ½ļ½’ļ¼‰ ė¶„ģžė„¼ ķ¬ķ•Øķ•˜ėŠ” ķ”„ė”œėøŒģ— ģ˜ķ•œ ķ‘œģ  ļ¼¤ļ¼®ļ¼” ė° ļ¼²ļ¼®ļ¼”ģ˜ ģŗ”ģ³
CN102031235B (zh) 2010-11-09 2012-07-25 äø­å›½å†œäøšå¤§å­¦ äø€ē§ē²Ŗ肠ēƒčŒanse228及其åŗ”ē”Ø
EP2455092A1 (en) 2010-11-11 2012-05-23 Nestec S.A. Non-replicating probiotic micro-organisms protect against upper respiratory tract infections
US20120128644A1 (en) 2010-11-24 2012-05-24 Oragenics, Inc. Use of Bacteria to Treat and Prevent Respiratory Infections
CN102093967B (zh) 2010-12-02 2013-01-30 äø­å›½å†œäøšē§‘学院ē‰¹äŗ§ē ”ē©¶ę‰€ äø€ę Ŗę°“č²‚ęŗå±Žč‚ ēƒčŒåŠå…¶åŗ”ē”Ø
ES2389547B1 (es) 2010-12-07 2013-08-08 Consejo Superior De Investigaciones CientĆ­ficas (Csic) Bifidobacterium cect 7765 y su uso en la prevenciĆ³n y/o tratamiento del sobrepeso, la obesidad y patologĆ­as asociadas.
WO2012097012A1 (en) 2011-01-10 2012-07-19 Cleveland Biolabs, Inc. Use of toll-like receptor agonist for treating cancer
EP2481299B1 (en) 2011-01-31 2016-12-07 Dr. Fischer Gesundheitsprodukte GmbH Bifidobacterium bifidum strains for application in gastrointestinal diseases
JP5840368B2 (ja) 2011-02-02 2016-01-06 ć‚«ćƒ«ćƒ”ć‚¹ę Ŗ式会ē¤¾ 関ēƀē‚Žäŗˆé˜²ę”¹å–„ē”Øē‰©č³Ŗ
CN103491969A (zh) 2011-02-09 2014-01-01 ꋉē»“ę²ƒå…¬åø ę¢å¤å’Œé‡å»ŗč‚ é“å¾®ē”Ÿē‰©ē¾¤ēš„合ē”Ÿē“ ē»„合ē‰©
US9968638B2 (en) 2011-03-09 2018-05-15 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
BRPI1100857A2 (pt) 2011-03-18 2013-05-21 Eduardo Nowill Alexandre agente imunomodulador e suas combinaƇƕes, seu uso e mƉtodo imunoterƁpico para a recontextualizaƇƧo, reprogramaƇƧo e reconduƇƧo do sistema imune em tempo real
WO2012140636A1 (en) 2011-04-11 2012-10-18 Alimentary Health Limited A probiotic formulation
WO2012142605A1 (en) 2011-04-15 2012-10-18 Samaritan Health Services Rapid recolonization deployment agent
CA2833633A1 (en) 2011-04-20 2012-10-26 Jason Fisher Composition and method for enhancing an immune response
WO2012158517A1 (en) 2011-05-13 2012-11-22 Glycosyn LLC The use of purified 2'-fucosyllactose, 3-fucosyllactose and lactodifucotetraose as prebiotics
MX359082B (es) * 2011-05-23 2018-09-11 Washington State Univ Research Foundation Uso de agentes estabilizantes de pigmento fotosintĆ©tico para regular la maduraciĆ³n y calidad de frutas y vegetales.
KR20120133133A (ko) 2011-05-30 2012-12-10 ķ•œźµ­ ķ•œģ˜ķ•™ ģ—°źµ¬ģ› ģƒģ•½ ģ¶”ģ¶œė¬¼ ė˜ėŠ” ģ“ģ˜ ģœ ģ‚°ź·  ė°œķšØė¬¼ģ„ ķ¬ķ•Øķ•˜ėŠ” ķ˜øķ”źø° ģ§ˆķ™˜ģ˜ ģ˜ˆė°© ė˜ėŠ” ģ¹˜ė£Œģš© ģ”°ģ„±ė¬¼
US20140171339A1 (en) 2011-06-06 2014-06-19 The University Of North Carolina At Chapel Hill Methods and kits for detecting adenomas, colorectal cancer, and uses thereof
GB201110095D0 (en) 2011-06-15 2011-07-27 Danisco Method of treatment
JP2013005759A (ja) 2011-06-24 2013-01-10 Kyodo Milk Industry Co Ltd ćƒžć‚¦ć‚¹č…øå†…čŒå¢ć®ęŽØęø¬ę–¹ę³•
JP6222626B2 (ja) 2011-07-07 2017-11-01 é•·å²”é¦™ę–™ę Ŗ式会ē¤¾ ćƒ•ćƒ«ć‚Æćƒˆćƒ¼ć‚¹åø収阻害剤
WO2013008102A2 (en) 2011-07-14 2013-01-17 R.E.D. Laboratories N.V../ S.A. Methods and compositions for evaluating and/or treating chronic immune diseases
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
US20130022575A1 (en) 2011-07-19 2013-01-24 Microbial Rx Systems and methods of replacing intestinal flora
CN102304483A (zh) 2011-08-12 2012-01-04 北äŗ¬é‡‘ę³°å¾—ē”Ÿē‰©ē§‘ęŠ€č‚”ä»½ęœ‰é™å…¬åø äø€ę Ŗ鄲ē”Øå±Žč‚ ēƒčŒåŠå…¶åŗ”ē”Ø
KR101261872B1 (ko) 2011-08-23 2013-05-14 ėŒ€ķ•œėƼźµ­ (ģ‹ķ’ˆģ˜ģ•½ķ’ˆģ•ˆģ „ģ²˜ģž„) ģž„ė‚“ ėÆøģƒė¬¼ ķšØģ†Œė³µķ•©ģ²“ ė° ģ“ģ˜ ģ œģ”°ė°©ė²•
US20140363397A1 (en) * 2011-09-14 2014-12-11 Queen's University At Kingston Method for treatment of disorders of the gastrointestinal system
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
CN103857402A (zh) 2011-10-11 2014-06-11 é˜æåŸŗ姆医čÆ公åø åŒ…ę‹¬åŽŒę°§åŸ¹å…»ēš„äŗŗē±»č‚ é“å¾®ē”Ÿē‰©ē¾¤ēš„ē»„合ē‰©
CN103082292B (zh) 2011-11-02 2015-03-04 ę·±åœ³åŽå¤§åŸŗ因ē ”ē©¶é™¢ ē½—ę–Æ갏菌(Roseburia)åœØę²»ē–—å’Œé¢„é˜²č‚„胖ē›ø关ē–¾ē—…äø­ēš„åŗ”ē”Ø
CN102373172B (zh) 2011-11-03 2013-03-20 北äŗ¬é¾™ē§‘ę–¹čˆŸē”Ÿē‰©å·„ēØ‹ęŠ€ęœÆęœ‰é™å…¬åø äø€ę Ŗå±Žč‚ ēƒčŒåŠå…¶åŗ”ē”Ø
ES2993669T3 (en) 2011-12-01 2025-01-03 Univ Tokyo Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
ES2408279B1 (es) 2011-12-15 2014-09-09 Universidad De Las Palmas De Gran Canaria Bacteria acido lĆ”ctica probiĆ³tica
ITBG20120010A1 (it) 2012-02-24 2013-08-25 Milano Politecnico Dispositivo per l'addestramento chirurgico
ITMI20120471A1 (it) 2012-03-26 2013-09-27 Giovanni Mogna Composizione a base di ceppi di batteri bifidobacterium longum in grado di aiutare il prolungamento della vita
JP5792105B2 (ja) 2012-03-27 2015-10-07 ę£®ę°øä¹³ę„­ę Ŗ式会ē¤¾ 惩ć‚Æ惈āˆ’ļ½Žāˆ’ćƒ“ć‚Ŗćƒ¼ć‚¹ļ½‰ć®č£½é€ ę–¹ę³•
JP6201982B2 (ja) 2012-03-30 2017-09-27 å‘³ć®ē“ ę Ŗ式会ē¤¾ ē³–å°æē—…čŖ˜čµ·ē“°čŒ
WO2013154826A2 (en) 2012-04-11 2013-10-17 Nestec Sa Methods for diagnosing impending diarrhea
GB201206599D0 (en) 2012-04-13 2012-05-30 Univ Manchester Probiotic bacteria
CN104507483A (zh) 2012-04-13 2015-04-08 ę³¢å£«é”æ学院ē†äŗ‹ä¼š ē›Šē”Ÿå…ƒē»„合ē‰©åŠä½æē”Øę–¹ę³•
US10130665B2 (en) 2012-05-18 2018-11-20 Genome Research Limited Method for identifying bacteria for bacteriotherapy
ES2436251B1 (es) 2012-05-25 2014-10-08 Consejo Superior De Investigaciones CientĆ­ficas (Csic) Bacteroides cect 7771 y su uso en la prevenciĆ³n y tratamiento de sobrepeso, obesidad y alteraciones metabĆ³licas e inmunolĆ³gicas.
WO2013181694A1 (en) 2012-06-04 2013-12-12 Gaurav Agrawal Compositions and methods for treating crohn's disease and related conditions and infections
CN102743420A (zh) 2012-06-06 2012-10-24 äøŠęµ·äŗ¤é€šå¤§å­¦ ę”¹å–„č‚ é“čŒē¾¤ē»“ęž„ēš„ę–¹ę³•åŠåŗ”ē”Ø
WO2014001368A1 (en) 2012-06-25 2014-01-03 Orega Biotech Il-17 antagonist antibodies
AU2013298645B2 (en) 2012-07-31 2016-11-03 SociƩtƩ des Produits NestlƩ S.A. Nutritional composition for promoting musculoskeletal health in patients with inflammatory bowel disease (IBD)
WO2014019271A1 (en) 2012-08-01 2014-02-06 Bgi Shenzhen Biomarkers for diabetes and usages thereof
WO2014036182A2 (en) 2012-08-29 2014-03-06 California Institute Of Technology Diagnosis and treatment of autism spectrum disorder
MX2015002210A (es) 2012-08-29 2015-05-08 Salix Pharmaceuticals Inc Composiciones laxantes y metodos para tratar estreƱimiento y enfermedades y condiciones gastrointestinales relacionadas.
CA2884816A1 (en) 2012-09-13 2014-03-20 Massachusetts Institute Of Technology Programmable drug delivery profiles of tumor-targeted bacteria
KR101473058B1 (ko) 2012-09-19 2014-12-16 ģ£¼ģ‹ķšŒģ‚¬ ģŽŒė°”ģ“ģ˜¤ķ… ź³¼ėƼģ„± ėŒ€ģž„ ģ¦ķ›„źµ° ģ˜ˆė°© ė˜ėŠ” ģ¹˜ė£Œģš© ģ”°ģ„±ė¬¼
CN103652322B (zh) 2012-09-21 2016-02-10 äø“ę²‚ę€ē§‘ē”Ÿē‰©ē§‘ęŠ€ęœ‰é™å…¬åø äø€ē§å«ä¹³é…ø菌ēš„复合ē›Šē”ŸčŒé„²ę–™ę·»åŠ å‰‚ēš„åˆ¶å¤‡ę–¹ę³•
WO2014053608A1 (en) 2012-10-03 2014-04-10 Metabogen Ab Identification of a person having risk for atherosclerosis and associated diseases by the person's gut microbiome and the prevention of such diseases
FR2997091B1 (fr) 2012-10-22 2016-05-06 Fond Mediterranee Infection Utilisation d'un compose antioxydant pour la culture de bacteries sensibles a la tension en oxygene
WO2014070225A1 (en) 2012-10-30 2014-05-08 Deerland Enzymes, Inc. Prebiotic compositions comprising one or more types of bacteriophage
CN104755092A (zh) 2012-10-30 2015-07-01 雀巢äŗ§å“ęŠ€ęœÆę“åŠ©ęœ‰é™å…¬åø ē”ØäŗŽé€’送协同免ē–«ä½œē”Øēš„包含微ē²’å’Œē›Šē”ŸčŒēš„ē»„合ē‰©
BR112015009975A2 (pt) 2012-11-01 2017-07-11 Academisch Ziekenhuis Groningen mĆ©todos e composiƧƵes para a estimulaĆ§Ć£o das bactĆ©rias benĆ©ficas no trato gastrointestinal
WO2014075745A1 (en) 2012-11-19 2014-05-22 UniversitƩ Catholique de Louvain Use of akkermansia for treating metabolic disorders
US8906668B2 (en) * 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
SG11201503966PA (en) * 2012-11-23 2015-06-29 Seres Health Inc Synergistic bacterial compositions and methods of production and use thereof
EP2922555A4 (en) 2012-11-26 2016-06-15 Borody Thomas J COMPOSITIONS FOR THE RESTORATION OF A FƄKALBIOZƖNOSE AND METHOD FOR THE PRODUCTION AND USE THEREOF
WO2014093655A2 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains
EP3031921B1 (en) 2012-12-12 2025-03-12 The Broad Institute, Inc. Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
CN113355357B (zh) 2012-12-12 2024-12-03 åøƒē½—å¾·ē ”ē©¶ę‰€ęœ‰é™å…¬åø åƹē”ØäŗŽåŗåˆ—ę“ēŗµēš„ę”¹čæ›ēš„ē³»ē»Ÿć€ę–¹ę³•å’Œé…¶ē»„合ē‰©čæ›č”Œēš„å·„ē؋化和优化
US20140193464A1 (en) 2013-01-08 2014-07-10 Imagilin Technology, Llc Effects of probiotics on humans and animals under environmental or biological changes
JP2016509003A (ja) 2013-02-04 2016-03-24 ć‚»ćƒ¬ć‚¹ ć‚»ćƒ©ćƒ”ćƒ„ćƒ¼ćƒ†ć‚£ć‚Æć‚¹ ć‚¤ćƒ³ć‚³ćƒ¼ćƒćƒ¬ć‚¤ćƒ†ćƒƒćƒ‰ ēµ„ęˆē‰©ćŠć‚ˆć³ę–¹ę³•
US10973861B2 (en) 2013-02-04 2021-04-13 Seres Therapeutics, Inc. Compositions and methods
EP3536328B1 (en) 2013-02-22 2021-10-27 The Regents of The University of California Food or beverage product, or probiotic composition, comprising lactobacillus johnsonii 456
BR112015020819A2 (pt) 2013-03-05 2017-07-18 Academisch Ziekenhuis Groningen uso de faecalibacterium prausnitzii htf-f (dsm 26943) para supressĆ£o de inflamaĆ§Ć£o
EP2971148A4 (en) 2013-03-14 2016-08-17 Seres Therapeutics Inc METHODS OF DETECTING PATHOGENS AND ENRICHING FROM MATERIALS AND COMPOSITIONS
AU2014239883B2 (en) 2013-03-14 2019-01-17 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
WO2014145958A2 (en) 2013-03-15 2014-09-18 Seres Health, Inc. Network-based microbial compositions and methods
WO2014150094A1 (en) 2013-03-15 2014-09-25 University Of Florida Research Foundation, Inc. Butyrogenic bacteria as probiotics to treat clostridium difficile
CN103142656A (zh) 2013-03-18 2013-06-12 å¹æ州ēŸ„光ē”Ÿē‰©ē§‘ęŠ€ęœ‰é™å…¬åø č„†å¼±ę‹Ÿę†čŒåœØåˆ¶å¤‡é˜²ę²»ē»“č‚ ē™Œē»„合ē‰©äø­ēš„åŗ”ē”Ø
CN103156888A (zh) 2013-03-18 2013-06-19 å¹æ州ēŸ„光ē”Ÿē‰©ē§‘ęŠ€ęœ‰é™å…¬åø č„†å¼±ę‹Ÿę†čŒåœØåˆ¶å¤‡ę²»ē–—ē‚Žē—‡ę€§č‚ ē—…ē»„合ē‰©äø­ēš„åŗ”ē”Ø
CN103146620A (zh) 2013-03-25 2013-06-12 å¹æ州ēŸ„光ē”Ÿē‰©ē§‘ęŠ€ęœ‰é™å…¬åø å…·ęœ‰ē›Šē”ŸčŒē‰¹ę€§ēš„č„†å¼±ę‹Ÿę†čŒ
JP2014196260A (ja) 2013-03-29 2014-10-16 公ē«‹å¤§å­¦ę³•äŗŗ儈č‰ÆēœŒē«‹åŒ»ē§‘大学 ę…¢ę€§é–‰å”žę€§č‚ŗē–¾ę‚£ć®äŗˆé˜²åˆćÆę²»ē™‚ē”Øēµ„ęˆē‰©
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
CA2911826C (en) 2013-05-10 2022-08-23 California Institute Of Technology Probiotic prevention and treatment of colon cancer
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
KR102099503B1 (ko) 2013-06-05 2020-04-09 ė¦¬ė°”ģ“ģ˜¤ķ‹±ģŠ¤, ģøģ½”ķ¼ė ˆģ“ķ‹°ė“œ ėÆøģƒė¬¼ģƒ ė³µģ› ģš”ė²•(mrt) ģ”°ģ„±ė¬¼
US20160120915A1 (en) 2013-06-10 2016-05-05 New York University Methods for manipulating immune responses by altering microbiota
WO2014200334A1 (en) 2013-06-14 2014-12-18 N.V. Nutricia Synbiotic composition for treatment of infections in allergic patients
WO2015003001A1 (en) 2013-07-01 2015-01-08 The Washington University Methods for identifying supplements that increase gut colonization by an isolated bacterial species, and compositions derived therefrom
EP3016511B1 (en) 2013-07-02 2019-10-09 Austrianova Singapore Pte Ltd. A method of freeze-drying encapsulated cells, compositions suitable for freezing of encapsulated cells and use of such compositions
WO2015003305A1 (zh) 2013-07-08 2015-01-15 吉ē‘žé«˜ę–°ē§‘ęŠ€č‚”ä»½ęœ‰é™å…¬åø ē”µå­ēƒŸē›’
WO2015006355A2 (en) 2013-07-09 2015-01-15 Puretech Ventures, Llc Compositions containing combinations of bioactive molecules derived from microbiota for treatment of disease
JP6637885B2 (ja) 2013-07-21 2020-01-29 ćƒšćƒ³ćƒ‡ćƒ„ćƒ©ćƒ  ć‚»ćƒ©ćƒ”ćƒ„ćƒ¼ćƒ†ć‚£ć‚Æć‚¹ļ¼Œ ć‚¤ćƒ³ć‚³ćƒ¼ćƒćƒ¬ć‚¤ćƒ†ćƒƒćƒ‰ 惞悤ć‚Æ惭惐悤ć‚Ŗćƒ¼ćƒ ć®ē‰¹ę€§č§£ę˜Žć€ćƒ¢ćƒ‹ć‚æćƒŖćƒ³ć‚°ć€ćŠć‚ˆć³å‡¦ē½®ć®ćŸć‚ć®ę–¹ę³•ćŠć‚ˆć³ć‚·ć‚¹ćƒ†ćƒ 
US20160192689A1 (en) 2013-07-31 2016-07-07 Wikifoods, Inc. Encapsulated functional food compositions
EP3033091B1 (en) 2013-08-16 2022-09-07 Versitech Limited Probiotic composition and use thereof in the prevention and treatment of hepatocellular carcinoma
CN103509741B (zh) 2013-08-22 2015-02-18 ę²³åŒ—å†œäøšå¤§å­¦ åøƒåŠ³ē‰¹čŒauh-jld56及其åœØē‰›č’”č‹·å…ƒč½¬åŒ–äø­ēš„åŗ”ē”Ø
US10203329B2 (en) 2013-09-12 2019-02-12 The Johns Hopkins University Biofilm formation to define risk for colon cancer
PL3071052T3 (pl) 2013-10-18 2020-07-27 Innovachildfood Ab Zbilansowany pod względem odżywczym złożony posiłek dla niemowląt i małych dzieci oraz sposĆ³b otrzymywania wspomnianego posiłku
PL229020B1 (pl) 2013-11-13 2018-05-30 Inst Biotechnologii Surowic I Szczepionek Biomed Spolka Akcyjna Nowy szczep Bifidobacterium breve
CN105979952B (zh) 2013-11-25 2022-04-08 čµ›é‡Œę–Æę²»ē–—å…¬åø 协同ē»†čŒē»„合ē‰©ä»„åŠå…¶åˆ¶é€ ę–¹ę³•å’Œē”Ø途
US9956282B2 (en) 2013-12-16 2018-05-01 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
CN103981117B (zh) 2013-12-24 2018-10-26 北äŗ¬å¤§ä¼Ÿå˜‰ē”Ÿē‰©ęŠ€ęœÆč‚”ä»½ęœ‰é™å…¬åø äø€ę Ŗé«˜ęŠ—é€†ę€§å±Žč‚ ēƒčŒåŠå…¶åŸ¹å…»ę–¹ę³•å’Œåŗ”ē”Ø
CN103981115B (zh) 2013-12-24 2018-10-26 北äŗ¬å¤§ä¼Ÿå˜‰ē”Ÿē‰©ęŠ€ęœÆč‚”ä»½ęœ‰é™å…¬åø äø€ę Ŗé«˜ęŠ—é€†ę€§å±Žč‚ ēƒčŒåŠå…¶åŗ”ē”Ø
CN103820363B (zh) 2014-01-27 2016-02-24 ē¦å»ŗēœå†œäøšē§‘学院ē”Ÿē‰©ęŠ€ęœÆē ”ē©¶ę‰€ äø€ē§å±Žč‚ ēƒčŒčŒē²‰ēš„制备äøŽåŗ”ē”Ø
CN103865846B (zh) 2014-02-27 2016-03-30 ę‰¬å·žē»æäæē”Ÿē‰©ē§‘ęŠ€ęœ‰é™å…¬åø äø€ē§å±Žč‚ ēƒčŒåŠå…¶åˆ¶å¤‡ę–¹ę³•
CN103849590B (zh) 2014-03-25 2016-07-06 äøŠęµ·äŗ¤é€šå¤§å­¦ äø€ę Ŗ耐é…øēŸ­åŒę­§ę†čŒBB8dpH及其åŗ”ē”Ø
KR101683474B1 (ko) 2014-03-26 2016-12-08 ģ£¼ģ‹ķšŒģ‚¬ ģŽŒė°”ģ“ģ˜¤ķ… ź³¼ėƼģ„± ėŒ€ģž„ ģ¦ķ›„źµ° ģ˜ˆė°© ė˜ėŠ” ģ¹˜ė£Œģš© ģ”°ģ„±ė¬¼
US9783858B2 (en) 2014-04-02 2017-10-10 Northwestern University Altered microbiome of chronic pelvic pain
US20150374760A1 (en) 2014-04-09 2015-12-31 Jose U. Scher Methods for treating psoriasis and psoriatic arthritis
KR101583546B1 (ko) 2014-04-09 2016-01-11 źµ­ė¦½ģ•”ģ„¼ķ„° ģœ ģ „ģž ė‹¤ķ˜•ģ„±ģ„ ģ“ģš©ķ•œ ģ†Œė¼ķŽ˜ė‹™ ģ¹˜ė£Œģ— ėŒ€ķ•œ ė°˜ģ‘ģ„± ģ˜ˆģø”ė°©ė²•
AU2015244700B2 (en) 2014-04-10 2020-08-27 Riken Compositions and methods for induction of Th17 cells
CN104195075B (zh) 2014-08-14 2017-04-19 ē”Ÿåˆē”Ÿē‰©ē§‘ęŠ€č‚”ä»½ęœ‰é™å…¬åø äø€ē§å±Žč‚ ēƒčŒef08及包含它ēš„é„²ę–™ę·»åŠ ē‰©å’Œé„²ę–™
WO2015168534A1 (en) 2014-05-02 2015-11-05 Novogy, Inc. Therapeutic treatment of gastrointestinal microbial imbalances through competitive microbe displacement
US11730716B2 (en) 2014-05-08 2023-08-22 Kiora Pharmaceuticals Gmbh Compounds for treating ophthalmic diseases and disorders
WO2016019506A1 (en) 2014-08-05 2016-02-11 BGI Shenzhen Co.,Limited Use of eubacterium in the prevention and treatment for colorectal cancer related diseases
WO2016033439A2 (en) 2014-08-28 2016-03-03 Yale University Compositions and methods for the treating an inflammatory disease or disorder
WO2016036615A1 (en) 2014-09-03 2016-03-10 California Institute Of Technology Microbe-based modulation of serotonin biosynthesis
CN104546932A (zh) 2014-09-30 2015-04-29 ę·±åœ³åŽå¤§åŸŗ因ē§‘ęŠ€ęœ‰é™å…¬åø åµå½¢ę‹Ÿę†čŒåœØę²»ē–—ęˆ–é¢„é˜²ē±»é£Žę¹æę€§å…³čŠ‚ē‚Žęˆ–å…¶ē›ø关ē–¾ē—…äø­ēš„åŗ”ē”Ø
CN104546940A (zh) 2014-09-30 2015-04-29 ę·±åœ³åŽå¤§åŸŗ因ē§‘ęŠ€ęœ‰é™å…¬åø å¹³åøøꋟꝆ菌åœØę²»ē–—ęˆ–é¢„é˜²ē±»é£Žę¹æę€§å…³čŠ‚ē‚Žęˆ–å…¶ē›ø关ē–¾ē—…äø­ēš„åŗ”ē”Ø
CN104546942A (zh) 2014-09-30 2015-04-29 ę·±åœ³åŽå¤§åŸŗ因ē§‘ęŠ€ęœ‰é™å…¬åø å¤šę°ę‹Ÿę†čŒåœØę²»ē–—ęˆ–é¢„é˜²ē±»é£Žę¹æę€§å…³čŠ‚ē‚Žęˆ–å…¶ē›ø关ē–¾ē—…äø­ēš„åŗ”ē”Ø
CN104546935A (zh) 2014-09-30 2015-04-29 ę·±åœ³åŽå¤§åŸŗ因ē§‘ęŠ€ęœ‰é™å…¬åø å¤šå½¢ę‹Ÿę†čŒåœØę²»ē–—ęˆ–é¢„é˜²ē±»é£Žę¹æę€§å…³čŠ‚ē‚Žęˆ–å…¶ē›ø关ē–¾ē—…äø­ēš„åŗ”ē”Ø
CN104546933A (zh) 2014-09-30 2015-04-29 ę·±åœ³åŽå¤§åŸŗ因ē§‘ęŠ€ęœ‰é™å…¬åø ē²ŖꋟꝆ菌åœØę²»ē–—ęˆ–é¢„é˜²ē±»é£Žę¹æę€§å…³čŠ‚ē‚Žęˆ–å…¶ē›ø关ē–¾ē—…äø­ēš„åŗ”ē”Ø
CN104546934B (zh) * 2014-09-30 2019-04-09 ę·±åœ³åŽå¤§åŸŗ因ē§‘ęŠ€ęœ‰é™å…¬åø ē²Ŗå‰ÆꋟꝆ菌åœØę²»ē–—ęˆ–é¢„é˜²ē±»é£Žę¹æę€§å…³čŠ‚ē‚Žęˆ–å…¶ē›ø关ē–¾ē—…äø­ēš„åŗ”ē”Ø
WO2016057671A1 (en) 2014-10-07 2016-04-14 University Of Virginia Patent Foundation Compositions and methods for preventing and treating infection
CN107249611A (zh) 2014-10-24 2017-10-13 čæ›åŒ–ē”Ÿē‰©ē³»ē»Ÿč‚”ä»½ęœ‰é™å…¬åø ę“»åŒ–ēš„åŒę­§ę†čŒåŠå…¶åŗ”ē”Øę–¹ę³•
CA2966360C (en) 2014-10-30 2023-09-05 California Institute Of Technology Compositions and methods comprising bacteria for improving behavior in neurodevelopmental disorders
WO2016069801A1 (en) 2014-10-30 2016-05-06 California Institute Of Technology Compositions and methods comprising bacteria for improving behavior in neurodecelopmental disorders
CA2964480A1 (en) 2014-10-31 2016-05-06 Whole Biome Inc. Methods and compositions relating to microbial treatment and diagnosis of disorders
CN104435000A (zh) 2014-11-12 2015-03-25 ę±Ÿå—å¤§å­¦ ä¹³é…ø菌åƹę”Æ갔ē®”å“®å–˜ę²»ē–—äø­ēš„åŗ”ē”Ø
WO2016086161A1 (en) 2014-11-25 2016-06-02 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prƩbiotiques, et leurs procƩdƩs d'utilisation pour la modulation du microbiome
AR103260A1 (es) 2014-12-23 2017-04-26 4D Pharma Res Ltd ModulaciĆ³n inmunitaria
EP3400953A1 (en) 2014-12-23 2018-11-14 4D Pharma Research Limited Pirin polypeptide and immune modulation
CN104560820B (zh) 2014-12-30 2017-10-20 ę­å·žåøˆčŒƒå¤§å­¦ å±Žč‚ ēƒčŒkq2.6及åŗ”ē”Ø
US10231941B2 (en) 2015-01-23 2019-03-19 Temple Universityā€”Of The Commonwealth System of Higher Educaton Use of short chain fatty acids in cancer prevention
CN105982919A (zh) 2015-02-26 2016-10-05 ēŽ‹ę±‰ęˆ ē”Ÿē‰©å‡é€Ÿå‰‚ꊗē™ŒęŠ€ęœÆ
WO2016139217A1 (en) 2015-03-04 2016-09-09 Ab-Biotics, S.A. Composition comprising anaerobically cultivated human intestinal microbiota
WO2016149449A1 (en) 2015-03-18 2016-09-22 Tufts University Compositions and methods for preventing colorectal cancer
WO2016149687A1 (en) 2015-03-18 2016-09-22 Whole Biome, Inc. Methods and compositions relating to microbial treatment and diagnosis of skin disorders
PE20180673A1 (es) 2015-06-01 2018-04-19 Univ Chicago Tratamiento contra el cancer por manipulacion de la microflora comensal
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactƩriennes
WO2016203221A1 (en) 2015-06-15 2016-12-22 4D Pharma Research Limited Compositions comprising bacterial strains
NZ737752A (en) 2015-06-15 2022-02-25 4D Pharma Res Ltd Compositions comprising bacterial strains
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactƩriennes
SMT201900588T1 (it) 2015-06-15 2019-11-13 4D Pharma Res Limited Blautia stercoris e wexlerae per uso nel trattamento di malattie infiammatorie ed autoimmuni
CN105112333A (zh) 2015-08-31 2015-12-02 ę±Ÿå—å¤§å­¦ äø€ē§å…·ęœ‰č‰Æå„½č‚ é“å®šę®–čƒ½åŠ›ēš„é•æåŒę­§ę†čŒåŠē­›é€‰ę–¹ę³•å’Œåŗ”ē”Ø
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
CN108513545B (zh) 2015-11-20 2020-11-03 4D制čÆē ”ē©¶ęœ‰é™å…¬åø 包含ē»†čŒčŒę Ŗēš„ē»„合ē‰©
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
WO2017091753A1 (en) 2015-11-25 2017-06-01 Memorial Sloan-Kettering Cancer Center Methods and compositions for reducing vancomycin-resistant enterococci infection or colonization
ME03487B (me) 2016-03-04 2020-01-20 4D Pharma Plc Kompozicije koje sadrže blautia bakterijske sojeve za liječenje visceralne hipersenzitivnosti
EP3429604A1 (en) 2016-03-14 2019-01-23 Holobiome, Inc. Modulation of the gut microbiome to treat mental disorders or diseases of the central nervous system
TWI802545B (zh) 2016-07-13 2023-05-21 č‹±å•†ļ¼”ļ¼¤č£½č—„ęœ‰é™å…¬åø 包含ē“°čŒčŒę Ŗ之ēµ„合ē‰©
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
US20190314427A1 (en) 2016-12-16 2019-10-17 Evelo Biosciences, Inc. Methods of treating cancer using parabacteroides
WO2018112365A2 (en) 2016-12-16 2018-06-21 Evelo Biosciences, Inc. Methods of treating colorectal cancer and melanoma using parabacteroides goldsteinii
RU2761873C2 (ru) 2016-12-23 2021-12-13 ŠšŃŠ¹Š¾ Š®Š½ŠøŠ²ŠµŃ€ŃŠøтŠø ŠšŠ¾Š¼ŠæŠ¾Š·ŠøцŠøŠø Šø сŠæŠ¾ŃŠ¾Š±Ń‹ Š“Š»Ń ŠøŠ½Š“уŠŗцŠøŠø cd8+ t-ŠŗŠ»ŠµŃ‚Š¾Šŗ

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