|
JPH0637520B2
(ja)
*
|
1985-07-03 |
1994-05-18 |
味の素株式会社 |
ポリペプチド
|
|
WO1987005330A1
(en)
|
1986-03-07 |
1987-09-11 |
Michel Louis Eugene Bergh |
Method for enhancing glycoprotein stability
|
|
US4973577A
(en)
|
1986-04-04 |
1990-11-27 |
The Salk Institute For Biological Studies |
FSH-releasing peptides
|
|
US5080891A
(en)
|
1987-08-03 |
1992-01-14 |
Ddi Pharmaceuticals, Inc. |
Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5198346A
(en)
|
1989-01-06 |
1993-03-30 |
Protein Engineering Corp. |
Generation and selection of novel DNA-binding proteins and polypeptides
|
|
US5096815A
(en)
|
1989-01-06 |
1992-03-17 |
Protein Engineering Corporation |
Generation and selection of novel dna-binding proteins and polypeptides
|
|
EP0548276A4
(en)
|
1990-09-13 |
1993-12-29 |
Children's Hospital Medical Center Of Northern California |
Method for increasing red blood cell production by treatment with activin or activin-related peptides
|
|
US5118667A
(en)
|
1991-05-03 |
1992-06-02 |
Celtrix Pharmaceuticals, Inc. |
Bone growth factors and inhibitors of bone resorption for promoting bone formation
|
|
US20050186593A1
(en)
|
1991-05-10 |
2005-08-25 |
The Salk Institute For Biological Studies |
Cloning and recombinant production of CRF receptor(s)
|
|
US6162896A
(en)
|
1991-05-10 |
2000-12-19 |
The Salk Institute For Biological Studies |
Recombinant vertebrate activin receptors
|
|
EP0542971A1
(en)
|
1991-05-10 |
1993-05-26 |
The Salk Institute For Biological Studies |
CLONING AND RECOMBINANT PRODUCTION OF RECEPTOR(S) OF THE ACTIVIN/TGF-$g(b) SUPERFAMILY
|
|
US5885794A
(en)
|
1991-05-10 |
1999-03-23 |
The Salk Institute For Biological Studies |
Recombinant production of vertebrate activin receptor polypeptides and identification of receptor DNAs in the activin/TGF-β superfamily
|
|
EP0592562B1
(en)
|
1991-06-25 |
1999-01-07 |
Genetics Institute, Inc. |
Bmp-9 compositions
|
|
US6287816B1
(en)
|
1991-06-25 |
2001-09-11 |
Genetics Institute, Inc. |
BMP-9 compositions
|
|
AU3968793A
(en)
*
|
1992-04-02 |
1993-11-08 |
United States Of America, As Represented By The Secretary Of Health And Human Services |
Use of restriction endonucleases against viruses, including HIV
|
|
US6692925B1
(en)
|
1992-11-17 |
2004-02-17 |
Ludwig Institute For Cancer Research |
Proteins having serine/threonine kinase domains, corresponding nucleic acid molecules, and their use
|
|
US5808007A
(en)
|
1993-01-12 |
1998-09-15 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor-3
|
|
JPH09501305A
(ja)
|
1993-05-12 |
1997-02-10 |
ジェネティックス・インスティテュート・インコーポレイテッド |
Ｂｍｐ−１０組成物
|
|
US5637480A
(en)
|
1993-05-12 |
1997-06-10 |
Genetics Institute, Inc. |
DNA molecules encoding bone morphogenetic protein-10
|
|
US5677196A
(en)
|
1993-05-18 |
1997-10-14 |
University Of Utah Research Foundation |
Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
|
|
US5831050A
(en)
|
1993-06-07 |
1998-11-03 |
Creative Biomolecules, Inc. |
Morphogen cell surface receptor
|
|
JPH09503673A
(ja)
|
1993-10-14 |
1997-04-15 |
プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ |
ニューロン細胞の誘導および維持法
|
|
US5525490A
(en)
|
1994-03-29 |
1996-06-11 |
Onyx Pharmaceuticals, Inc. |
Reverse two-hybrid method
|
|
US5658876A
(en)
|
1994-04-28 |
1997-08-19 |
The General Hospital Corporation |
Activin antagonists as novel contraceptives
|
|
EP0756628B1
(en)
*
|
1994-04-29 |
2007-11-14 |
Curis, Inc. |
Morphogenic protein-specific cell surface receptors and uses therefor
|
|
IL114397A0
(en)
*
|
1994-07-01 |
1995-10-31 |
Bioph Biotech Entw Pharm Gmbh |
Growth/differentiation factor of the TGF-beta-family
|
|
US5760010A
(en)
|
1995-01-01 |
1998-06-02 |
Klein; Ira |
Method of treating liver disorders with a macrolide antibiotic
|
|
IL117175A
(en)
*
|
1995-02-20 |
2005-11-20 |
Sankyo Co |
Osteoclastogenesis inhibitory factor protein
|
|
US5814565A
(en)
|
1995-02-23 |
1998-09-29 |
University Of Utah Research Foundation |
Integrated optic waveguide immunosensor
|
|
NZ306767A
(en)
|
1995-04-11 |
2000-03-27 |
Univ Johns Hopkins |
Method of identifying molecular interactions employing counterselection and at least two hybrid molecules or two hybrid systems
|
|
US6132988A
(en)
*
|
1995-10-27 |
2000-10-17 |
Takeda Chemical Industries, Ltd. |
DNA encoding a neuronal cell-specific receptor protein
|
|
GB9526131D0
(en)
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Recombinant chimeric receptors
|
|
US6004780A
(en)
|
1996-03-26 |
1999-12-21 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
US20050244867A1
(en)
|
1996-03-26 |
2005-11-03 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
AU721196B2
(en)
|
1996-10-25 |
2000-06-29 |
G.D. Searle & Co. |
Circularly permuted erythropoietin receptor agonists
|
|
US6605699B1
(en)
*
|
1997-01-21 |
2003-08-12 |
Human Genome Sciences, Inc. |
Galectin-11 polypeptides
|
|
US6034062A
(en)
|
1997-03-13 |
2000-03-07 |
Genetics Institute, Inc. |
Bone morphogenetic protein (BMP)-9 compositions and their uses
|
|
US6231880B1
(en)
|
1997-05-30 |
2001-05-15 |
Susan P. Perrine |
Compositions and administration of compositions for the treatment of blood disorders
|
|
ES2320603T3
(es)
|
1997-07-30 |
2009-05-25 |
Emory University |
Sistemas de expresion, vectores, adn, proteinas de mineralizacion osea novedosos.
|
|
US6656475B1
(en)
*
|
1997-08-01 |
2003-12-02 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
|
|
US6891082B2
(en)
|
1997-08-01 |
2005-05-10 |
The Johns Hopkins University School Of Medicine |
Transgenic non-human animals expressing a truncated activintype II receptor
|
|
AU8666398A
(en)
|
1997-08-01 |
1999-02-22 |
Johns Hopkins University School Of Medicine, The |
Methods to identify growth differentiation factor (gdf) receptors
|
|
US6696260B1
(en)
*
|
1997-08-01 |
2004-02-24 |
The Johns Hopkins University School Of Medicine |
Methods to identify growth differentiation factor (GDF) binding proteins
|
|
US6953662B2
(en)
|
1997-08-29 |
2005-10-11 |
Human Genome Sciences, Inc. |
Follistatin-3
|
|
JP2001513982A
(ja)
|
1997-08-29 |
2001-09-11 |
ヒューマン ジノーム サイエンシーズ， インコーポレイテッド |
フォリスタチン−３
|
|
RU2221809C2
(ru)
|
1997-10-03 |
2004-01-20 |
Тугаи Сейяку Кабусики Кайся |
Способ получения природного гуманизированного антитела
|
|
US6696411B1
(en)
|
1998-04-22 |
2004-02-24 |
Cornell Research Foundation, Inc. |
Canine erythropoietin gene and recombinant protein
|
|
AU4572899A
(en)
|
1998-06-16 |
2000-01-05 |
Biogen, Inc. |
Variant type ii tgf-beta receptor fusion proteins and methods
|
|
JP2002524514A
(ja)
*
|
1998-09-17 |
2002-08-06 |
イーライ・リリー・アンド・カンパニー |
タンパク質製剤
|
|
EP1116792B1
(en)
|
1998-09-22 |
2007-01-24 |
Long Yu |
New human growth differentiation factor encoding sequence and polypeptide encoded by such dna sequence and producing method thereof
|
|
US6472179B2
(en)
*
|
1998-09-25 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Receptor based antagonists and methods of making and using
|
|
US6548634B1
(en)
|
1998-09-30 |
2003-04-15 |
Chiron Corporation |
Synthetic peptides having FGF receptor affinity
|
|
US6238860B1
(en)
|
1998-11-05 |
2001-05-29 |
Dyax Corp. |
Binding moieties for human parvovirus B19
|
|
US6777205B1
(en)
|
1998-11-06 |
2004-08-17 |
Sterrenbeld Biotechnologie North America, Inc. |
Host cells expressing recombinant human erythropoietin
|
|
US20040009535A1
(en)
*
|
1998-11-27 |
2004-01-15 |
Celltech R&D, Inc. |
Compositions and methods for increasing bone mineralization
|
|
ATE481487T1
(de)
*
|
1998-11-27 |
2010-10-15 |
Ucb Sa |
Zusammensetzungen und verfahren zur erhöhung der knochenmineralisierung
|
|
MXPA01007366A
(es)
|
1999-01-21 |
2002-06-04 |
Metamorphix Inc |
Inhibidores de factores de crecimiento y diferenciacion y usos de los mismos.
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
AU777783B2
(en)
|
1999-04-19 |
2004-10-28 |
Kyowa Hakko Kogyo Co. Ltd. |
Proliferation inhibitor for androgen-independent tumor
|
|
US6468543B1
(en)
|
1999-05-03 |
2002-10-22 |
Zymogenetics, Inc. |
Methods for promoting growth of bone using ZVEGF4
|
|
CA2390292A1
(en)
|
1999-11-12 |
2001-05-25 |
Maxygen Holdings Ltd. |
Interferon gamma conjugates
|
|
IL150198A0
(en)
|
1999-12-15 |
2002-12-01 |
Res Dev Foundation |
Betaglycan as an inhibin receptor and uses thereof
|
|
US20030224501A1
(en)
|
2000-03-17 |
2003-12-04 |
Young Paul E. |
Bone morphogenic protein polynucleotides, polypeptides, and antibodies
|
|
JP4487376B2
(ja)
*
|
2000-03-31 |
2010-06-23 |
味の素株式会社 |
腎疾患治療剤
|
|
ME00673B
(me)
|
2000-05-15 |
2011-12-20 |
Hoffmann La Roche |
Nova farmaceutska smjesa
|
|
US6627424B1
(en)
|
2000-05-26 |
2003-09-30 |
Mj Bioworks, Inc. |
Nucleic acid modifying enzymes
|
|
US20030215913A1
(en)
|
2000-07-19 |
2003-11-20 |
Enrique Alvarez |
Nucleic acids, vectors, host cells, polypeptides, and uses thereof
|
|
US6632180B1
(en)
|
2000-09-07 |
2003-10-14 |
John H. Laragh |
Method for evaluating and treating hypertension
|
|
DE10045591A1
(de)
|
2000-09-15 |
2002-04-04 |
Klaus Pfizenmaier |
Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
|
|
EP2141243A3
(en)
|
2000-10-16 |
2010-01-27 |
Brystol-Myers Squibb Company |
Protein scaffolds for antibody mimics and other binding proteins
|
|
US7087224B2
(en)
|
2000-10-31 |
2006-08-08 |
Amgen Inc. |
Method of treating anemia by administering IL-1ra
|
|
DK1345959T3
(da)
|
2000-11-20 |
2011-09-05 |
Univ Illinois |
Membranscaffoldproteiner
|
|
AU2002236558A1
(en)
|
2000-12-01 |
2002-06-11 |
Regents Of The University Of California |
Method and composition for modulating bone growth
|
|
US20030082233A1
(en)
|
2000-12-01 |
2003-05-01 |
Lyons Karen M. |
Method and composition for modulating bone growth
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
TW200526779A
(en)
*
|
2001-02-08 |
2005-08-16 |
Wyeth Corp |
Modified and stabilized GDF propeptides and uses thereof
|
|
US20040132971A1
(en)
*
|
2001-02-09 |
2004-07-08 |
Haaning Jesper Mortensen |
Rank ligand-binding polypeptides
|
|
US20040132675A1
(en)
|
2002-02-08 |
2004-07-08 |
Calvin Kuo |
Method for treating cancer and increasing hematocrit levels
|
|
US7294472B2
(en)
*
|
2001-03-14 |
2007-11-13 |
Caden Biosciences |
Method for identifying modulators of G protein coupled receptor signaling
|
|
EP1369130A1
(en)
|
2001-03-16 |
2003-12-10 |
Takeda Chemical Industries, Ltd. |
Process for producing sustained release preparation
|
|
US20030082630A1
(en)
|
2001-04-26 |
2003-05-01 |
Maxygen, Inc. |
Combinatorial libraries of monomer domains
|
|
BRPI0209933B8
(pt)
|
2001-05-24 |
2021-05-25 |
Zymogenetics Inc |
proteína de fusão, e, molécula de ácido nucleico
|
|
EP1390497A2
(en)
|
2001-05-25 |
2004-02-25 |
Genset |
Human cdnas and proteins and uses thereof
|
|
AUPR638101A0
(en)
|
2001-07-13 |
2001-08-09 |
Bioa Pty Limited |
Composition and method for treatment of disease
|
|
CN102912016A
(zh)
|
2001-07-17 |
2013-02-06 |
帝人株式会社 |
通过测定PPARδ激活作用筛选物质的方法和药剂
|
|
US6855344B2
(en)
|
2001-07-17 |
2005-02-15 |
Integrated Chinese Medicine Holdings, Ltd. |
Compositions and methods for prostate and kidney health and disorders, an herbal preparation
|
|
KR100453877B1
(ko)
|
2001-07-26 |
2004-10-20 |
메덱스젠 주식회사 |
연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
|
|
US7320789B2
(en)
|
2001-09-26 |
2008-01-22 |
Wyeth |
Antibody inhibitors of GDF-8 and uses thereof
|
|
US6784154B2
(en)
|
2001-11-01 |
2004-08-31 |
University Of Utah Research Foundation |
Method of use of erythropoietin to treat ischemic acute renal failure
|
|
DK2298301T3
(en)
|
2001-12-06 |
2018-10-01 |
Fibrogen Inc |
MEDICINALS FOR TREATMENT OF ANEMIA ASSOCIATED WITH Kidney Disease
|
|
US20030144203A1
(en)
|
2001-12-19 |
2003-07-31 |
Voyager Pharmaceutical Corporation |
Methods for slowing senescence and treating and preventing diseases associated with senescence
|
|
US20060234918A1
(en)
|
2001-12-19 |
2006-10-19 |
Voyager Pharmaceutical Corporation |
Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors
|
|
US6998118B2
(en)
|
2001-12-21 |
2006-02-14 |
The Salk Institute For Biological Studies |
Targeted retrograde gene delivery for neuronal protection
|
|
WO2003068801A2
(en)
|
2002-02-11 |
2003-08-21 |
Genentech, Inc. |
Antibody variants with faster antigen association rates
|
|
EP1572909A4
(en)
|
2002-02-21 |
2007-06-06 |
Wyeth Corp |
PROTEIN CONTAINING A DOMAINE OF FOLLISTATIN
|
|
US20030219846A1
(en)
|
2002-02-28 |
2003-11-27 |
Pfizer Inc. |
Assay for activity of the ActRIIB kinase
|
|
WO2003087162A2
(en)
*
|
2002-04-18 |
2003-10-23 |
Mtm Laboratories Ag |
Neopeptides and methods useful for detection and treatment of cancer
|
|
DE10234192B4
(de)
|
2002-07-26 |
2009-11-26 |
Epoplus Gmbh Co.Kg |
Verwendung von Erythropoetin
|
|
US20050271637A1
(en)
|
2002-08-16 |
2005-12-08 |
Bodine Peter Van N |
BMP-2 estrogen responsive element and methods of using the same
|
|
AR047392A1
(es)
*
|
2002-10-22 |
2006-01-18 |
Wyeth Corp |
Neutralizacion de anticuerpos contra gdf 8 y su uso para tales fines
|
|
US20040223966A1
(en)
*
|
2002-10-25 |
2004-11-11 |
Wolfman Neil M. |
ActRIIB fusion polypeptides and uses therefor
|
|
AU2002953327A0
(en)
|
2002-12-12 |
2003-01-09 |
Monash University |
Methods of diagnosing prognosing and treating activin associated diseases and conditions
|
|
ATE419846T1
(de)
|
2003-02-07 |
2009-01-15 |
Prometic Biosciences Inc |
Fettsäuren mittlerer kettenlänge, glyceride und analoga als stimulatoren der erythropoiese
|
|
US20040197828A1
(en)
|
2003-03-26 |
2004-10-07 |
Gaddy Dana P. |
Method for diagnosis and treatment of bone turnover
|
|
WO2005028517A2
(en)
*
|
2003-05-09 |
2005-03-31 |
The General Hospital Corporation |
SOLUBLE TGF-β TYPE III RECEPTOR FUSION PROTEINS
|
|
RU2322261C2
(ru)
|
2003-06-02 |
2008-04-20 |
Уайт |
Применение ингибиторов миостатика (gdf8) в сочетании с кортикостероидами для лечения нервно-мышечных заболеваний
|
|
CA2529623A1
(en)
|
2003-06-16 |
2005-02-17 |
Celltech R & D, Inc. |
Antibodies specific for sclerostin and methods for increasing bone mineralization
|
|
WO2005009460A2
(en)
|
2003-07-25 |
2005-02-03 |
Medexis, S.A. |
Pharmaceutical composition comprising activin a, alk-4 or derivatives thereof for the treatment of ophthalmic disorders or cancer
|
|
US8895540B2
(en)
|
2003-11-26 |
2014-11-25 |
DePuy Synthes Products, LLC |
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
|
|
AU2005206277B2
(en)
*
|
2004-01-22 |
2011-06-23 |
Merck Patent Gmbh |
Anti-cancer antibodies with reduced complement fixation
|
|
US20050197292A1
(en)
*
|
2004-01-30 |
2005-09-08 |
Glennda Smithson |
Compositions and methods for treating T-cell mediated pathological conditions
|
|
WO2005094871A2
(en)
|
2004-03-26 |
2005-10-13 |
Acceleron Pharma Inc. |
Bmp-3 propeptides and related methods
|
|
CA2561809A1
(en)
*
|
2004-03-31 |
2005-10-20 |
Xencor, Inc. |
Bmp-7 variants with improved properties
|
|
WO2005113590A2
(en)
|
2004-05-12 |
2005-12-01 |
Acceleron Pharma Inc. |
Bmp10 propeptides and related methods
|
|
EP1771557B1
(en)
|
2004-06-24 |
2014-12-31 |
Acceleron Pharma Inc. |
GDF3 Propeptides and Related Methods
|
|
JP2008507288A
(ja)
|
2004-07-23 |
2008-03-13 |
アクセルロン ファーマ インコーポレーテッド |
ＡｃｔＲＩＩ受容体ポリペプチド、方法、および組成物
|
|
US8617815B2
(en)
|
2004-08-05 |
2013-12-31 |
The Regents Of The University Of California |
Molecules with effects on cellular development and function
|
|
AU2005272646A1
(en)
|
2004-08-12 |
2006-02-23 |
Wyeth |
Combination therapy for diabetes, obesity, and cardiovascular diseases using GDF-8 inhibitors
|
|
WO2006039400A2
(en)
|
2004-09-29 |
2006-04-13 |
Mount Sinai School Of Medicine Of New York University |
Fsh and fsh receptor modulator compositions and methods for inhibiting osteoclastic bone resorption and bone loss in osteoporosis
|
|
US20060234299A1
(en)
|
2004-11-16 |
2006-10-19 |
Avidia Research Institute |
Protein scaffolds and uses thereof
|
|
NL1027887C2
(nl)
|
2004-12-24 |
2006-06-27 |
Bosch Gmbh Robert |
Transmissie met gebombeerde poelieschijven en een drijfriem.
|
|
NZ538097A
(en)
|
2005-02-07 |
2006-07-28 |
Ovita Ltd |
Method and compositions for improving wound healing
|
|
WO2006088972A2
(en)
|
2005-02-16 |
2006-08-24 |
The General Hospital Corporation |
Use of modulatirs of compounds of tgf-beta superfamily to regulate hepcidin-mediated iron metabolism
|
|
EP1877075A4
(en)
|
2005-04-25 |
2008-07-30 |
Pfizer |
ANTIBODY TO MYOSTATIN
|
|
EP1884235A1
(en)
|
2005-04-26 |
2008-02-06 |
Ajinomoto Co., Inc. |
Myeloerythroid progenitor differentiation inducer
|
|
JP2007099764A
(ja)
|
2005-09-09 |
2007-04-19 |
Ajinomoto Co Inc |
血糖低下剤
|
|
JP2009510093A
(ja)
|
2005-09-28 |
2009-03-12 |
ザイモジェネティクス， インコーポレイテッド |
Ｉｌ−１７ａおよびｉｌ−１７ｆアンタゴニストならびにその使用方法
|
|
US8067562B2
(en)
|
2005-11-01 |
2011-11-29 |
Amgen Inc. |
Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1
|
|
US8128933B2
(en)
|
2005-11-23 |
2012-03-06 |
Acceleron Pharma, Inc. |
Method of promoting bone growth by an anti-activin B antibody
|
|
ES2649983T3
(es)
|
2005-11-23 |
2018-01-16 |
Acceleron Pharma, Inc. |
Antagonistas de activina-ActRIIa en su uso para promover el crecimiento óseo
|
|
WO2007067616A2
(en)
|
2005-12-06 |
2007-06-14 |
Amgen Inc |
Uses of myostatin antagonists
|
|
EP1966183A4
(en)
|
2005-12-20 |
2010-12-29 |
Merck Frosst Canada Ltd |
HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A-DELTA-9-DESATURASE
|
|
AU2006331770A1
(en)
|
2005-12-21 |
2007-07-05 |
Schering Corporation |
Treatment of nonalcoholic fatty liver disease using cholesterol lowering agents and H3 receptor antagonist/inverse agonist
|
|
WO2007076127A2
(en)
|
2005-12-22 |
2007-07-05 |
Biogen Idec Ma Inc |
Condensed imidazoles or pyrazoles and their use as transforming growth factor modulators
|
|
WO2007084977A2
(en)
*
|
2006-01-20 |
2007-07-26 |
Beckman Coulter, Inc. |
Low hemoglobin concentration cell percentage and method of use in detection of iron deficiency
|
|
WO2007087505A2
(en)
|
2006-01-25 |
2007-08-02 |
Wellstat Therapeutics Corporation |
Compounds for the treatment of metabolic disorders
|
|
KR20080098615A
(ko)
|
2006-02-28 |
2008-11-11 |
웰스태트 테러퓨틱스 코포레이션 |
물질대사 장애의 치료용 화합물
|
|
WO2007120767A2
(en)
|
2006-04-14 |
2007-10-25 |
Amgen Inc. |
Agonist erythropoietin receptor antibodies
|
|
WO2007123391A1
(en)
|
2006-04-20 |
2007-11-01 |
Academisch Ziekenhuis Leiden |
Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene.
|
|
US20080075692A1
(en)
*
|
2006-05-09 |
2008-03-27 |
Perrine Susan P |
Methods for treating blood disorders
|
|
TW200803123A
(en)
*
|
2006-06-02 |
2008-01-01 |
Delta Electronics Inc |
Power converter and magnetic structure thereof
|
|
ES2382993T3
(es)
|
2006-07-21 |
2012-06-15 |
Lyne Laboratories, Inc. |
Composición líquida de acetato de calcio
|
|
GB0615129D0
(en)
|
2006-07-29 |
2006-09-06 |
Univ Cardiff |
Anti-cancer activity of BMP-9 and BMP-10 and their use in cancer therapies
|
|
CL2007002567A1
(es)
|
2006-09-08 |
2008-02-01 |
Amgen Inc |
Proteinas aisladas de enlace a activina a humana.
|
|
US7547781B2
(en)
*
|
2006-09-11 |
2009-06-16 |
Curis, Inc. |
Quinazoline based EGFR inhibitors containing a zinc binding moiety
|
|
WO2008060139A1
(en)
|
2006-11-17 |
2008-05-22 |
Erasmus University Medical Center Rotterdam |
Methods for controlling mineralization of extracellular matrix, therapeutic methods based thereon and medicaments for use therein
|
|
US20100003190A1
(en)
|
2006-12-08 |
2010-01-07 |
Caritas St. Elizabeth's Medical Center Of Boston, Inc. |
Method for protecting renal tubular epithelial cells from radiocontrast nephropathy (RCN)
|
|
CA2672581A1
(en)
|
2006-12-14 |
2008-06-19 |
Forerunner Pharma Research Co., Ltd. |
Anti-claudin 3 monoclonal antibody and treatment and diagnosis of cancer using the same
|
|
CN104524548A
(zh)
|
2006-12-18 |
2015-04-22 |
阿塞勒隆制药公司 |
活化素-actrii拮抗剂及在提高红细胞水平中的用途
|
|
US8895016B2
(en)
|
2006-12-18 |
2014-11-25 |
Acceleron Pharma, Inc. |
Antagonists of activin-actriia and uses for increasing red blood cell levels
|
|
US20100028332A1
(en)
|
2006-12-18 |
2010-02-04 |
Acceleron Pharma Inc. |
Antagonists of actriib and uses for increasing red blood cell levels
|
|
MX2009008222A
(es)
*
|
2007-02-01 |
2009-10-12 |
Acceleron Pharma Inc |
Antagonistas de activina-actriia y usos para tratar o prevenir cancer de mama.
|
|
TW201803890A
(zh)
|
2007-02-02 |
2018-02-01 |
艾瑟勒朗法瑪公司 |
衍生自ＡｃｔＲＩＩＢ的變體與其用途
|
|
EA018221B1
(ru)
|
2007-02-09 |
2013-06-28 |
Акселерон Фарма Инк. |
АНТАГОНИСТЫ АКТИВИНА-ActRIIa И ПРИМЕНЕНИЕ ДЛЯ СТИМУЛЯЦИИ РОСТА КОСТИ У БОЛЬНЫХ РАКОМ
|
|
US8501678B2
(en)
|
2007-03-06 |
2013-08-06 |
Atara Biotherapeutics, Inc. |
Variant activin receptor polypeptides and uses thereof
|
|
US7947646B2
(en)
|
2007-03-06 |
2011-05-24 |
Amgen Inc. |
Variant activin receptor polypeptides
|
|
MX2009012934A
(es)
|
2007-06-01 |
2009-12-15 |
Wyeth Corp |
Metodos y composiciones para modular la actividad de bmp-10.
|
|
WO2009009059A1
(en)
|
2007-07-09 |
2009-01-15 |
Biogen Idec Ma Inc. |
Spiro compounds as antagonists of tgf-beta
|
|
US20090025308A1
(en)
*
|
2007-07-26 |
2009-01-29 |
Deans Brian W |
Seismic support and reinforcement systems
|
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
CA2685540C
(en)
|
2007-08-03 |
2018-10-16 |
Graham Michael Wynne |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
GB0715938D0
(en)
|
2007-08-15 |
2007-09-26 |
Vastox Plc |
Method of treatment of duchenne muscular dystrophy
|
|
WO2009025651A1
(en)
|
2007-08-17 |
2009-02-26 |
University Of Maine System Board Of Trustees |
Biologically active peptide and method of using the same
|
|
WO2009035629A1
(en)
|
2007-09-13 |
2009-03-19 |
Ludwig Institute Of Cancer Research |
Method for modifying cellular immune response by modulating activin activity
|
|
CN101861161B
(zh)
|
2007-09-18 |
2017-04-19 |
阿塞勒隆制药公司 |
活化素‑actriia拮抗剂和减少或抑制fsh分泌的用途
|
|
PE20091163A1
(es)
|
2007-11-01 |
2009-08-09 |
Wyeth Corp |
Anticuerpos para gdf8
|
|
AU2008330125B2
(en)
|
2007-11-21 |
2012-11-22 |
Amgen Inc. |
Wise binding antibodies and epitopes
|
|
JP5638961B2
(ja)
|
2008-03-13 |
2014-12-10 |
ザ ジェネラル ホスピタル コーポレイション |
Ｂｍｐシグナル伝達経路のインヒビター
|
|
WO2009137075A1
(en)
*
|
2008-05-06 |
2009-11-12 |
Acceleron Pharma Inc. |
Anti-activin antibodies and uses for promoting bone growth
|
|
JP2011523357A
(ja)
|
2008-05-06 |
2011-08-11 |
ジョスリン ダイアビーティス センター インコーポレイテッド |
褐色脂肪細胞分化を誘導するための方法および組成物
|
|
CN102131822A
(zh)
|
2008-06-26 |
2011-07-20 |
阿塞勒隆制药公司 |
进行激活素-ActRIIa拮抗剂给药和监测受治疗患者的方法
|
|
DK2318028T3
(da)
|
2008-06-26 |
2020-05-04 |
Acceleron Pharma Inc |
Antagonister af opløselig activin-aktriia og anvendelser til øgning af røde blodcelleniveauer
|
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
|
TW201803586A
(zh)
|
2008-08-14 |
2018-02-01 |
艾瑟勒朗法瑪公司 |
使用ｇｄｆ阱以增加紅血球水平
|
|
US20110293526A1
(en)
|
2008-11-20 |
2011-12-01 |
University Of Southern California |
Compositions and methods to modulate hair growth
|
|
JP5611222B2
(ja)
|
2008-11-26 |
2014-10-22 |
アムジエン・インコーポレーテツド |
アクチビンｉｉｂ受容体ポリペプチドの変異体及びその使用
|
|
AU2010204985A1
(en)
|
2009-01-13 |
2011-08-04 |
Acceleron Pharma Inc. |
Methods for increasing adiponectin
|
|
US8110355B2
(en)
|
2009-02-20 |
2012-02-07 |
GenRemedy, LLC |
Methods for identifying agents that inhibit cell migration, promote cell adhesion and prevent metastasis
|
|
PE20120532A1
(es)
|
2009-04-27 |
2012-05-18 |
Novartis Ag |
ANTICUERPOS ANTI-ActRIIB
|
|
KR20120049214A
(ko)
|
2009-06-08 |
2012-05-16 |
악셀레론 파마 인코포레이티드 |
발열성 지방세포를 증가시키는 방법
|
|
KR20180026795A
(ko)
|
2009-06-12 |
2018-03-13 |
악셀레론 파마 인코포레이티드 |
절두된 ＡｃｔＲＩＩＢ-ＦＣ 융합 단백질
|
|
AU2010282361B2
(en)
|
2009-08-13 |
2015-03-19 |
Acceleron Pharma Inc. |
Combined use of GDF traps and erythropoietin receptor activators to increase red blood cell levels
|
|
EP3202459B1
(en)
|
2009-09-09 |
2021-04-14 |
Acceleron Pharma Inc. |
Actriib antagonists and dosing and uses thereof for treating obesity or type 2 diabetes by regulating body fat content
|
|
AU2010315245B2
(en)
|
2009-11-03 |
2016-11-03 |
Acceleron Pharma Inc. |
Methods for treating fatty liver disease
|
|
EP3332796A1
(en)
|
2009-11-17 |
2018-06-13 |
Acceleron Pharma Inc. |
Actriib proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
|
|
WO2012027065A2
(en)
|
2010-08-27 |
2012-03-01 |
Celgene Corporation |
Combination therapy for treatment of disease
|
|
US8580922B2
(en)
|
2011-03-04 |
2013-11-12 |
Shire Human Genetic Therapies, Inc. |
Peptide linkers for polypeptide compositions and methods for using same
|
|
JP6472999B2
(ja)
|
2011-07-01 |
2019-02-20 |
ノバルティス アーゲー |
代謝障害を治療するための方法
|
|
KR20140084211A
(ko)
|
2011-10-17 |
2014-07-04 |
악셀레론 파마 인코포레이티드 |
효과가 없는 적혈구생성 치료를 위한 방법 및 조성물
|
|
US8765385B2
(en)
|
2011-10-27 |
2014-07-01 |
Ravindra Kumar |
Method of detection of neutralizing anti-actriib antibodies
|
|
WO2013063536A1
(en)
|
2011-10-27 |
2013-05-02 |
Acceleron Pharma, Inc. |
Actriib binding agents and uses thereof
|
|
CA2853187A1
(en)
|
2011-10-28 |
2013-05-02 |
Paranta Biosciences Limited |
A method of treating mucus hypersecretion
|
|
HK1203384A1
(en)
|
2011-12-19 |
2015-12-11 |
Amgen Inc. |
Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
WO2013186777A2
(en)
|
2012-06-14 |
2013-12-19 |
The Medical Researth, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center |
Use of blocking agents of bone morphogenie protein (bmp) signaling for the treatment of neuroinflammatory and neurodegenerative diseases
|
|
CN104411720B
(zh)
|
2012-07-02 |
2018-05-11 |
协和发酵麒麟株式会社 |
以抗bmp9抗体作为有效成分的、对肾性贫血、癌性贫血等贫血的治疗剂
|
|
HK1214504A1
(zh)
|
2012-10-24 |
2016-07-29 |
细胞基因公司 |
用於治療貧血的方法
|
|
CN104968801B
(zh)
|
2012-10-24 |
2021-06-15 |
细胞基因公司 |
用于治疗贫血症的生物标志物
|
|
WO2014064292A1
(en)
|
2012-10-26 |
2014-05-01 |
Universite Pierre Et Marie Curie (Paris 6) |
A method for preventing or treating atrial fibrillation
|
|
US10195249B2
(en)
|
2012-11-02 |
2019-02-05 |
Celgene Corporation |
Activin-ActRII antagonists and uses for treating bone and other disorders
|
|
MX373894B
(es)
|
2012-11-08 |
2020-07-09 |
Clearside Biomedical Inc |
Métodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
|
|
WO2014093531A1
(en)
|
2012-12-11 |
2014-06-19 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Modulation of myofiber repair by anti-myostatin in strategies with stem cells
|
|
US20140220033A1
(en)
|
2013-02-01 |
2014-08-07 |
Santa Maria Biotherapeutics, Inc. |
Administration of an Anti-Activin-A Compound to a Subject
|
|
EP2970940B1
(en)
|
2013-03-14 |
2018-07-25 |
Translate Bio, Inc. |
Mrna therapeutic compositions and use to treat diseases and disorders
|
|
TW201920262A
(zh)
|
2013-07-30 |
2019-06-01 |
美商再生元醫藥公司 |
抗活化素ａ之抗體及其用途
|
|
HK1219280A1
(zh)
|
2013-08-14 |
2017-03-31 |
Novartis Ag |
治疗偶发性包涵体肌炎之方法
|
|
CA2932463A1
(en)
|
2013-12-16 |
2015-06-25 |
Paranta Biosciences Limited |
Method of diagnosis and treatment
|
|
US20160333418A1
(en)
|
2014-01-14 |
2016-11-17 |
Santa Maria Biotherapeutics, Inc. |
Activin Inhibitor Response Prediction and Uses for Treatment
|
|
CN105992951A
(zh)
|
2014-01-27 |
2016-10-05 |
诺华股份有限公司 |
预测肌萎缩的生物标志物、方法和用途
|
|
JP6601687B2
(ja)
|
2014-03-31 |
2019-11-06 |
大日本住友製薬株式会社 |
進行性骨化性線維異形成症の予防剤及び治療剤
|
|
EP3808778A1
(en)
|
2014-04-18 |
2021-04-21 |
Acceleron Pharma Inc. |
Methods for increasing red blood cell levels and treating sickle-cell disease
|
|
TW201622746A
(zh)
|
2014-04-24 |
2016-07-01 |
諾華公司 |
改善或加速髖部骨折術後身體復原之方法
|
|
EA202090632A1
(ru)
|
2014-06-04 |
2020-07-31 |
Акселерон Фарма Инк. |
Способы и композиции для лечения расстройств с использованием фоллистатиновых полипептидов
|
|
PE20170471A1
(es)
|
2014-06-13 |
2017-05-14 |
Santa Maria Biotherapeutics Inc |
Polipeptidos receptores formulados y metodos relacionados
|
|
US20180125928A1
(en)
|
2015-05-13 |
2018-05-10 |
Celgene Corporation |
Treatment of beta-thalassemia using actrii ligand traps
|