|
JPH0637520B2
(ja)
*
|
1985-07-03 |
1994-05-18 |
味の素株式会社 |
ポリペプチド
|
|
WO1987005330A1
(en)
|
1986-03-07 |
1987-09-11 |
Michel Louis Eugene Bergh |
Method for enhancing glycoprotein stability
|
|
US4973577A
(en)
|
1986-04-04 |
1990-11-27 |
The Salk Institute For Biological Studies |
FSH-releasing peptides
|
|
US5080891A
(en)
|
1987-08-03 |
1992-01-14 |
Ddi Pharmaceuticals, Inc. |
Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5198346A
(en)
|
1989-01-06 |
1993-03-30 |
Protein Engineering Corp. |
Generation and selection of novel DNA-binding proteins and polypeptides
|
|
US5096815A
(en)
|
1989-01-06 |
1992-03-17 |
Protein Engineering Corporation |
Generation and selection of novel dna-binding proteins and polypeptides
|
|
AU8761391A
(en)
|
1990-09-13 |
1992-04-15 |
Children's Hospital Medical Center Of Northern California |
Method for increasing red blood cell production by treatment with activin or activin-related peptides
|
|
US5118667A
(en)
|
1991-05-03 |
1992-06-02 |
Celtrix Pharmaceuticals, Inc. |
Bone growth factors and inhibitors of bone resorption for promoting bone formation
|
|
WO1992020793A1
(en)
|
1991-05-10 |
1992-11-26 |
The Salk Institute For Biological Studies |
CLONING AND RECOMBINANT PRODUCTION OF RECEPTOR(S) OF THE ACTIVIN/TGF-β SUPERFAMILY
|
|
US6162896A
(en)
|
1991-05-10 |
2000-12-19 |
The Salk Institute For Biological Studies |
Recombinant vertebrate activin receptors
|
|
US5885794A
(en)
|
1991-05-10 |
1999-03-23 |
The Salk Institute For Biological Studies |
Recombinant production of vertebrate activin receptor polypeptides and identification of receptor DNAs in the activin/TGF-β superfamily
|
|
US20050186593A1
(en)
|
1991-05-10 |
2005-08-25 |
The Salk Institute For Biological Studies |
Cloning and recombinant production of CRF receptor(s)
|
|
US6287816B1
(en)
|
1991-06-25 |
2001-09-11 |
Genetics Institute, Inc. |
BMP-9 compositions
|
|
US5661007A
(en)
|
1991-06-25 |
1997-08-26 |
Genetics Institute, Inc. |
Bone morphogenetic protein-9 compositions
|
|
WO1993020207A1
(en)
*
|
1992-04-02 |
1993-10-14 |
The United States Of America, As Represented By The Secretary Of Health And Human Services |
Use of restriction endonucleases against viruses, including hiv
|
|
US6692925B1
(en)
|
1992-11-17 |
2004-02-17 |
Ludwig Institute For Cancer Research |
Proteins having serine/threonine kinase domains, corresponding nucleic acid molecules, and their use
|
|
EP1475440A3
(en)
|
1993-01-12 |
2004-11-17 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor-3
|
|
BR9406716A
(pt)
|
1993-05-12 |
1996-02-06 |
Genetics Inst |
Molécula de DNA isolada célula hospedeira vetor método para produzir uma proteina (BMP-10) polipeptideo de proteina-10 morfogenética de osso purificada (BMP-10) e molécula de DNA quimérica
|
|
US5637480A
(en)
|
1993-05-12 |
1997-06-10 |
Genetics Institute, Inc. |
DNA molecules encoding bone morphogenetic protein-10
|
|
US5677196A
(en)
|
1993-05-18 |
1997-10-14 |
University Of Utah Research Foundation |
Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
|
|
US5831050A
(en)
*
|
1993-06-07 |
1998-11-03 |
Creative Biomolecules, Inc. |
Morphogen cell surface receptor
|
|
ATE355369T1
(de)
|
1993-10-14 |
2006-03-15 |
Harvard College |
Verfahren zur induzierung und zur erhaltung neuronalen zellen
|
|
US5525490A
(en)
|
1994-03-29 |
1996-06-11 |
Onyx Pharmaceuticals, Inc. |
Reverse two-hybrid method
|
|
US5658876A
(en)
|
1994-04-28 |
1997-08-19 |
The General Hospital Corporation |
Activin antagonists as novel contraceptives
|
|
AU702163B2
(en)
*
|
1994-04-29 |
1999-02-18 |
Creative Biomolecules, Inc. |
Morphogenic protein-specific cell surface receptors and uses therefor
|
|
IL114397A0
(en)
*
|
1994-07-01 |
1995-10-31 |
Bioph Biotech Entw Pharm Gmbh |
Growth/differentiation factor of the TGF-beta-family
|
|
US5760010A
(en)
|
1995-01-01 |
1998-06-02 |
Klein; Ira |
Method of treating liver disorders with a macrolide antibiotic
|
|
IL117175A
(en)
*
|
1995-02-20 |
2005-11-20 |
Sankyo Co |
Osteoclastogenesis inhibitory factor protein
|
|
US5814565A
(en)
|
1995-02-23 |
1998-09-29 |
University Of Utah Research Foundation |
Integrated optic waveguide immunosensor
|
|
DE69636866D1
(en)
|
1995-04-11 |
2007-03-15 |
Gen Hospital Corp |
Reverse "two-hybrid"-systeme
|
|
US6132988A
(en)
*
|
1995-10-27 |
2000-10-17 |
Takeda Chemical Industries, Ltd. |
DNA encoding a neuronal cell-specific receptor protein
|
|
GB9526131D0
(en)
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Recombinant chimeric receptors
|
|
US6004780A
(en)
|
1996-03-26 |
1999-12-21 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
US20050244867A1
(en)
|
1996-03-26 |
2005-11-03 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
PL189756B1
(pl)
|
1996-10-25 |
2005-09-30 |
Searle & Co |
Polipeptyd ludzkiego agonisty receptora erytropoetyny (EPO), sposób jego wytwarzania i zastosowanie, cząsteczka kwasu nukleinowego, kompozycja, sposób selektywnego namnażania ex vivo erytroidalnych komórek progenitorowych
|
|
US6605699B1
(en)
*
|
1997-01-21 |
2003-08-12 |
Human Genome Sciences, Inc. |
Galectin-11 polypeptides
|
|
US6034062A
(en)
|
1997-03-13 |
2000-03-07 |
Genetics Institute, Inc. |
Bone morphogenetic protein (BMP)-9 compositions and their uses
|
|
US6231880B1
(en)
*
|
1997-05-30 |
2001-05-15 |
Susan P. Perrine |
Compositions and administration of compositions for the treatment of blood disorders
|
|
US6300127B1
(en)
|
1997-07-30 |
2001-10-09 |
Emory University |
Bone mineralization proteins, DNA, vectors, expression systems
|
|
US6656475B1
(en)
|
1997-08-01 |
2003-12-02 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
|
|
US6696260B1
(en)
*
|
1997-08-01 |
2004-02-24 |
The Johns Hopkins University School Of Medicine |
Methods to identify growth differentiation factor (GDF) binding proteins
|
|
AU8666398A
(en)
|
1997-08-01 |
1999-02-22 |
Johns Hopkins University School Of Medicine, The |
Methods to identify growth differentiation factor (gdf) receptors
|
|
US6891082B2
(en)
|
1997-08-01 |
2005-05-10 |
The Johns Hopkins University School Of Medicine |
Transgenic non-human animals expressing a truncated activintype II receptor
|
|
US6953662B2
(en)
*
|
1997-08-29 |
2005-10-11 |
Human Genome Sciences, Inc. |
Follistatin-3
|
|
WO1999010364A1
(en)
|
1997-08-29 |
1999-03-04 |
Human Genome Sciences, Inc. |
Follistatin-3
|
|
EP1020522B1
(en)
|
1997-10-03 |
2007-09-19 |
Chugai Seiyaku Kabushiki Kaisha |
Natural human antibody
|
|
US6696411B1
(en)
|
1998-04-22 |
2004-02-24 |
Cornell Research Foundation, Inc. |
Canine erythropoietin gene and recombinant protein
|
|
EP1087998A1
(en)
|
1998-06-16 |
2001-04-04 |
Biogen, Inc. |
Variant type ii tgf-beta receptor fusion proteins and methods
|
|
US6440930B1
(en)
*
|
1998-09-17 |
2002-08-27 |
Eli Lilly And Company |
Protein formulations
|
|
CA2343715C
(en)
|
1998-09-22 |
2004-05-18 |
Long Yu |
New human growth differentiation factor encoding sequence and polypeptide encoded by such dna sequence and producing method thereof
|
|
US6472179B2
(en)
*
|
1998-09-25 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Receptor based antagonists and methods of making and using
|
|
US6548634B1
(en)
|
1998-09-30 |
2003-04-15 |
Chiron Corporation |
Synthetic peptides having FGF receptor affinity
|
|
US6238860B1
(en)
|
1998-11-05 |
2001-05-29 |
Dyax Corp. |
Binding moieties for human parvovirus B19
|
|
US6777205B1
(en)
|
1998-11-06 |
2004-08-17 |
Sterrenbeld Biotechnologie North America, Inc. |
Host cells expressing recombinant human erythropoietin
|
|
US20040009535A1
(en)
*
|
1998-11-27 |
2004-01-15 |
Celltech R&D, Inc. |
Compositions and methods for increasing bone mineralization
|
|
EP1721979B1
(en)
*
|
1998-11-27 |
2010-09-15 |
Ucb, S.A. |
Compositions and methods for increasing bone mineralisation
|
|
ATE322681T1
(de)
|
1999-01-21 |
2006-04-15 |
Metamorphix Inc |
Inhibitoren für wachstumdifferenzierungsfaktor und ihre anwendungen
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
CA2365449A1
(en)
|
1999-04-19 |
2000-10-26 |
Kyowa Hakko Kogyo Co., Ltd. |
Inhibitor of the growth of androgen-independent tumor
|
|
US6468543B1
(en)
*
|
1999-05-03 |
2002-10-22 |
Zymogenetics, Inc. |
Methods for promoting growth of bone using ZVEGF4
|
|
BR0015506A
(pt)
|
1999-11-12 |
2002-07-23 |
Maxygen Holdings Ltd |
Conjugados de interferon gama, métodos para sua preparação, composições farmacêuticas que compreendem ás moléculas e seu uso no tratamento de doenças
|
|
EP1237565B1
(en)
|
1999-12-15 |
2006-03-08 |
Research Development Foundation |
Betaglycan as an inhibin receptor and uses thereof
|
|
US20030224501A1
(en)
|
2000-03-17 |
2003-12-04 |
Young Paul E. |
Bone morphogenic protein polynucleotides, polypeptides, and antibodies
|
|
JP4487376B2
(ja)
*
|
2000-03-31 |
2010-06-23 |
味の素株式会社 |
腎疾患治療剤
|
|
MXPA02011303A
(es)
|
2000-05-15 |
2003-04-25 |
Hoffmann La Roche |
Nueva composicion farmaceutica.
|
|
US6627424B1
(en)
|
2000-05-26 |
2003-09-30 |
Mj Bioworks, Inc. |
Nucleic acid modifying enzymes
|
|
WO2002008277A2
(en)
|
2000-07-19 |
2002-01-31 |
Eli Lilly And Company |
Nucleic acids, vectors, host cells, polypeptides, and uses thereof
|
|
US6632180B1
(en)
|
2000-09-07 |
2003-10-14 |
John H. Laragh |
Method for evaluating and treating hypertension
|
|
DE10045591A1
(de)
|
2000-09-15 |
2002-04-04 |
Klaus Pfizenmaier |
Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
|
|
EP2141243A3
(en)
|
2000-10-16 |
2010-01-27 |
Brystol-Myers Squibb Company |
Protein scaffolds for antibody mimics and other binding proteins
|
|
US7087224B2
(en)
|
2000-10-31 |
2006-08-08 |
Amgen Inc. |
Method of treating anemia by administering IL-1ra
|
|
WO2002040501A2
(en)
|
2000-11-20 |
2002-05-23 |
The Board Of Trustees Of The University Of Illinois |
Membrane scaffold proteins
|
|
US20030082233A1
(en)
|
2000-12-01 |
2003-05-01 |
Lyons Karen M. |
Method and composition for modulating bone growth
|
|
AU2002236558A1
(en)
|
2000-12-01 |
2002-06-11 |
Regents Of The University Of California |
Method and composition for modulating bone growth
|
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
TW200526779A
(en)
*
|
2001-02-08 |
2005-08-16 |
Wyeth Corp |
Modified and stabilized GDF propeptides and uses thereof
|
|
US20040132971A1
(en)
*
|
2001-02-09 |
2004-07-08 |
Haaning Jesper Mortensen |
Rank ligand-binding polypeptides
|
|
US20040132675A1
(en)
|
2002-02-08 |
2004-07-08 |
Calvin Kuo |
Method for treating cancer and increasing hematocrit levels
|
|
US7294472B2
(en)
*
|
2001-03-14 |
2007-11-13 |
Caden Biosciences |
Method for identifying modulators of G protein coupled receptor signaling
|
|
WO2002074340A1
(fr)
|
2001-03-16 |
2002-09-26 |
Takeda Chemical Industries, Ltd. |
Procede de fabrication d'une preparation a liberation continue
|
|
DE60236861D1
(de)
|
2001-04-26 |
2010-08-12 |
Amgen Mountain View Inc |
Kombinatorische bibliotheken von monomerdomänen
|
|
ATE542545T1
(de)
|
2001-05-24 |
2012-02-15 |
Zymogenetics Inc |
Taci-immunoglobulin-fusionsproteine
|
|
EP1390497A2
(en)
*
|
2001-05-25 |
2004-02-25 |
Genset |
Human cdnas and proteins and uses thereof
|
|
AUPR638101A0
(en)
|
2001-07-13 |
2001-08-09 |
Bioa Pty Limited |
Composition and method for treatment of disease
|
|
US6855344B2
(en)
*
|
2001-07-17 |
2005-02-15 |
Integrated Chinese Medicine Holdings, Ltd. |
Compositions and methods for prostate and kidney health and disorders, an herbal preparation
|
|
WO2003008967A1
(en)
|
2001-07-17 |
2003-01-30 |
Teijin Limited |
Method of selecting substance characterized by assaying ppard activating effect and drug
|
|
KR100453877B1
(ko)
|
2001-07-26 |
2004-10-20 |
메덱스젠 주식회사 |
연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
|
|
US7320789B2
(en)
|
2001-09-26 |
2008-01-22 |
Wyeth |
Antibody inhibitors of GDF-8 and uses thereof
|
|
US6784154B2
(en)
|
2001-11-01 |
2004-08-31 |
University Of Utah Research Foundation |
Method of use of erythropoietin to treat ischemic acute renal failure
|
|
EP1487472B1
(en)
|
2001-12-06 |
2019-06-26 |
Fibrogen, Inc. |
Treatment of ischemic or hypoxic conditions using heterocyclic carboxamides
|
|
US20060234918A1
(en)
|
2001-12-19 |
2006-10-19 |
Voyager Pharmaceutical Corporation |
Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors
|
|
US20030144203A1
(en)
|
2001-12-19 |
2003-07-31 |
Voyager Pharmaceutical Corporation |
Methods for slowing senescence and treating and preventing diseases associated with senescence
|
|
US6998118B2
(en)
|
2001-12-21 |
2006-02-14 |
The Salk Institute For Biological Studies |
Targeted retrograde gene delivery for neuronal protection
|
|
MXPA04007583A
(es)
|
2002-02-11 |
2005-04-25 |
Genentech Inc |
Variantes de anticuerpo con tasas mas rapidas de asociacion a antigeno.
|
|
IL163525A0
(en)
|
2002-02-21 |
2005-12-18 |
Wyeth Corp |
A follistatin domain containing protein
|
|
US20030219846A1
(en)
|
2002-02-28 |
2003-11-27 |
Pfizer Inc. |
Assay for activity of the ActRIIB kinase
|
|
AU2003232485A1
(en)
*
|
2002-04-18 |
2003-10-27 |
Mtm Laboratories Ag |
Neopeptides and methods useful for detection and treatment of cancer
|
|
DE10234192B4
(de)
|
2002-07-26 |
2009-11-26 |
Epoplus Gmbh Co.Kg |
Verwendung von Erythropoetin
|
|
BR0313729A
(pt)
|
2002-08-16 |
2005-06-21 |
Wyeth Corp |
Elemento respondente a estrogênio bmp-2 e métodos de uso do mesmo
|
|
US7261893B2
(en)
|
2002-10-22 |
2007-08-28 |
Wyeth |
Neutralizing antibodies against GDF-8 and uses therefor
|
|
US20040223966A1
(en)
|
2002-10-25 |
2004-11-11 |
Wolfman Neil M. |
ActRIIB fusion polypeptides and uses therefor
|
|
AU2002953327A0
(en)
|
2002-12-12 |
2003-01-09 |
Monash University |
Methods of diagnosing prognosing and treating activin associated diseases and conditions
|
|
ES2255467T3
(es)
|
2003-02-07 |
2009-05-01 |
Prometic Biosciences Inc. |
Acidos grasos de cadena de longitud media, gliceridos y analogos como estimuladores de eritropoyesis.
|
|
WO2004086953A2
(en)
|
2003-03-26 |
2004-10-14 |
The Board Of Trustees Of The University Of Arkansas |
Method for diagnosis and treatment of bone turnover
|
|
WO2005028517A2
(en)
|
2003-05-09 |
2005-03-31 |
The General Hospital Corporation |
SOLUBLE TGF-β TYPE III RECEPTOR FUSION PROTEINS
|
|
UA85055C2
(ru)
|
2003-06-02 |
2008-12-25 |
Уайт |
Применение ингибиторов миостатика (gdf8) в сочетании с кортикостероидами для лечения нервно-мышечных заболеваний
|
|
NO345763B1
(no)
|
2003-06-16 |
2021-07-19 |
Celltech R&D Inc |
Immunogen og antistoffer spesifikke for sklerostin, samt farmasøytiske preparater for å øke benmineralisering.
|
|
WO2005009460A2
(en)
|
2003-07-25 |
2005-02-03 |
Medexis, S.A. |
Pharmaceutical composition comprising activin a, alk-4 or derivatives thereof for the treatment of ophthalmic disorders or cancer
|
|
US8895540B2
(en)
|
2003-11-26 |
2014-11-25 |
DePuy Synthes Products, LLC |
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
|
|
ATE443724T1
(de)
*
|
2004-01-22 |
2009-10-15 |
Merck Patent Gmbh |
Antikrebs-antikörper mit reduzierter komplementfixierung
|
|
US20050197292A1
(en)
*
|
2004-01-30 |
2005-09-08 |
Glennda Smithson |
Compositions and methods for treating T-cell mediated pathological conditions
|
|
CA2561317A1
(en)
*
|
2004-03-26 |
2005-10-13 |
Acceleron Pharma Inc. |
Bmp-3 propeptides and related methods
|
|
AU2005230854A1
(en)
*
|
2004-03-31 |
2005-10-20 |
Xencor, Inc |
BMP-7 variants with improved properties
|
|
WO2005113590A2
(en)
|
2004-05-12 |
2005-12-01 |
Acceleron Pharma Inc. |
Bmp10 propeptides and related methods
|
|
EP1771557B1
(en)
|
2004-06-24 |
2014-12-31 |
Acceleron Pharma Inc. |
GDF3 Propeptides and Related Methods
|
|
DK2332977T3
(en)
|
2004-07-23 |
2016-02-29 |
Acceleron Pharma Inc |
ActRII receptor polypeptides
|
|
JP2008508878A
(ja)
|
2004-08-05 |
2008-03-27 |
ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア |
細胞の発生および機能に対する効果を有する分子
|
|
WO2006020884A2
(en)
|
2004-08-12 |
2006-02-23 |
Wyeth |
Combination therapy for diabetes, obesity, and cardiovascular diseases using gdf-8 inhibitors
|
|
CA2581896C
(en)
|
2004-09-29 |
2015-11-10 |
Mount Sinai School Of Medicine Of New York University |
Fsh and fsh receptor modulator compositions and methods for inhibiting osteoclastic bone resorption and bone loss in osteoporosis
|
|
AU2005307789A1
(en)
|
2004-11-16 |
2006-05-26 |
Avidia Research Institute |
Protein scaffolds and uses thereof
|
|
NL1027887C2
(nl)
|
2004-12-24 |
2006-06-27 |
Bosch Gmbh Robert |
Transmissie met gebombeerde poelieschijven en een drijfriem.
|
|
NZ538097A
(en)
|
2005-02-07 |
2006-07-28 |
Ovita Ltd |
Method and compositions for improving wound healing
|
|
EP1858541B1
(en)
|
2005-02-16 |
2012-07-25 |
The General Hospital Corporation |
Use of bmp antagonists to regulate hepcidin-mediated iron metabolism and treat iron deficiency
|
|
EA201100642A1
(ru)
|
2005-04-25 |
2011-12-30 |
Пфайзер Инк. |
Антитела к миостатину
|
|
WO2006115274A1
(ja)
|
2005-04-26 |
2006-11-02 |
Ajinomoto Co., Inc. |
骨髄赤血球前駆細胞分化促進剤
|
|
JP2007099764A
(ja)
|
2005-09-09 |
2007-04-19 |
Ajinomoto Co Inc |
血糖低下剤
|
|
EP1931697B1
(en)
|
2005-09-28 |
2010-09-15 |
ZymoGenetics, Inc. |
Il-17a and il-17f antagonists and methods of using the same
|
|
US8067562B2
(en)
|
2005-11-01 |
2011-11-29 |
Amgen Inc. |
Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1
|
|
US8128933B2
(en)
|
2005-11-23 |
2012-03-06 |
Acceleron Pharma, Inc. |
Method of promoting bone growth by an anti-activin B antibody
|
|
CA3045808C
(en)
*
|
2005-11-23 |
2022-08-16 |
Acceleron Pharma, Inc. |
Activin-actriia antagonists and uses for promoting bone growth
|
|
JP2009518422A
(ja)
|
2005-12-06 |
2009-05-07 |
アムジェン インコーポレイテッド |
ミオスタチン・アンタゴニストの使用
|
|
WO2007071023A1
(en)
|
2005-12-20 |
2007-06-28 |
Merck Frosst Canada Ltd. |
Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
|
|
WO2007075702A2
(en)
|
2005-12-21 |
2007-07-05 |
Schering Corporation |
Treatment of nonalcoholic fatty liver disease using cholesterol lowering agents and h3 receptor antagonist/inverse agonist
|
|
WO2007076127A2
(en)
|
2005-12-22 |
2007-07-05 |
Biogen Idec Ma Inc |
Condensed imidazoles or pyrazoles and their use as transforming growth factor modulators
|
|
US7361510B2
(en)
*
|
2006-01-20 |
2008-04-22 |
Beckman Coulter, Inc. |
Methods of detection of iron deficiency
|
|
WO2007087505A2
(en)
|
2006-01-25 |
2007-08-02 |
Wellstat Therapeutics Corporation |
Compounds for the treatment of metabolic disorders
|
|
KR20080098615A
(ko)
|
2006-02-28 |
2008-11-11 |
웰스태트 테러퓨틱스 코포레이션 |
물질대사 장애의 치료용 화합물
|
|
CA2650131A1
(en)
|
2006-04-14 |
2007-10-25 |
Amgen Inc. |
Agonist erythropoietin receptor antibodies
|
|
WO2007123391A1
(en)
|
2006-04-20 |
2007-11-01 |
Academisch Ziekenhuis Leiden |
Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene.
|
|
CA2652235A1
(en)
*
|
2006-05-09 |
2007-11-22 |
Hemaquest Pharmaceuticals, Inc. |
Methods for treating blood disorders
|
|
TW200803123A
(en)
*
|
2006-06-02 |
2008-01-01 |
Delta Electronics Inc |
Power converter and magnetic structure thereof
|
|
MX2009000722A
(es)
*
|
2006-07-21 |
2009-06-11 |
Lyne Lab |
Composiciones liquidas de acetato de calcio.
|
|
GB0615129D0
(en)
|
2006-07-29 |
2006-09-06 |
Univ Cardiff |
Anti-cancer activity of BMP-9 and BMP-10 and their use in cancer therapies
|
|
CL2007002567A1
(es)
|
2006-09-08 |
2008-02-01 |
Amgen Inc |
Proteinas aisladas de enlace a activina a humana.
|
|
US7547781B2
(en)
*
|
2006-09-11 |
2009-06-16 |
Curis, Inc. |
Quinazoline based EGFR inhibitors containing a zinc binding moiety
|
|
WO2008060139A1
(en)
|
2006-11-17 |
2008-05-22 |
Erasmus University Medical Center Rotterdam |
Methods for controlling mineralization of extracellular matrix, therapeutic methods based thereon and medicaments for use therein
|
|
US20100003190A1
(en)
|
2006-12-08 |
2010-01-07 |
Caritas St. Elizabeth's Medical Center Of Boston, Inc. |
Method for protecting renal tubular epithelial cells from radiocontrast nephropathy (RCN)
|
|
CN101663322A
(zh)
|
2006-12-14 |
2010-03-03 |
株式会社未来创药研究所 |
抗紧密连接蛋白3单克隆抗体以及使用该抗体的癌症的治疗和诊断
|
|
US8895016B2
(en)
|
2006-12-18 |
2014-11-25 |
Acceleron Pharma, Inc. |
Antagonists of activin-actriia and uses for increasing red blood cell levels
|
|
MX373050B
(es)
|
2006-12-18 |
2020-05-21 |
Acceleron Pharma Inc |
Antagonistas de activina-actrii y usos para incrementar los niveles de globulos rojos.
|
|
US20100028332A1
(en)
|
2006-12-18 |
2010-02-04 |
Acceleron Pharma Inc. |
Antagonists of actriib and uses for increasing red blood cell levels
|
|
RU2473362C2
(ru)
|
2007-02-01 |
2013-01-27 |
Акселерон Фарма Инк. |
АНТАГОНИСТЫ АКТИВИНА-ActRIIa-Fc И ИХ ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ
|
|
TW201907946A
(zh)
|
2007-02-02 |
2019-03-01 |
美商艾瑟勒朗法瑪公司 |
衍生自ＡｃｔＲＩＩＢ的變體與其用途
|
|
WO2008100384A2
(en)
*
|
2007-02-09 |
2008-08-21 |
Acceleron Pharma Inc. |
Activin-actriia antagonists and uses for promoting bone growth in cancer patients
|
|
US8501678B2
(en)
|
2007-03-06 |
2013-08-06 |
Atara Biotherapeutics, Inc. |
Variant activin receptor polypeptides and uses thereof
|
|
TW201718635A
(zh)
|
2007-03-06 |
2017-06-01 |
安美基公司 |
變異之活動素受體多肽及其用途
|
|
JP2010529041A
(ja)
|
2007-06-01 |
2010-08-26 |
ワイス・エルエルシー |
Ｂｍｐ−１０活性を調整する方法および組成物
|
|
WO2009009059A1
(en)
|
2007-07-09 |
2009-01-15 |
Biogen Idec Ma Inc. |
Spiro compounds as antagonists of tgf-beta
|
|
US20090025308A1
(en)
*
|
2007-07-26 |
2009-01-29 |
Deans Brian W |
Seismic support and reinforcement systems
|
|
RS55735B1
(sr)
|
2007-08-03 |
2017-07-31 |
Summit (Oxford) Ltd |
Kombinacije lekova za lečenje dišenove mišićne distrofije
|
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
GB0715938D0
(en)
|
2007-08-15 |
2007-09-26 |
Vastox Plc |
Method of treatment of duchenne muscular dystrophy
|
|
WO2009025651A1
(en)
|
2007-08-17 |
2009-02-26 |
University Of Maine System Board Of Trustees |
Biologically active peptide and method of using the same
|
|
WO2009035629A1
(en)
|
2007-09-13 |
2009-03-19 |
Ludwig Institute Of Cancer Research |
Method for modifying cellular immune response by modulating activin activity
|
|
CN101861161B
(zh)
|
2007-09-18 |
2017-04-19 |
阿塞勒隆制药公司 |
活化素‑actriia拮抗剂和减少或抑制fsh分泌的用途
|
|
PE20091163A1
(es)
|
2007-11-01 |
2009-08-09 |
Wyeth Corp |
Anticuerpos para gdf8
|
|
BRPI0820387A2
(pt)
|
2007-11-21 |
2015-05-26 |
Amgen Inc |
Agentes de ligação de wise e epítopos
|
|
US8507501B2
(en)
|
2008-03-13 |
2013-08-13 |
The Brigham And Women's Hospital, Inc. |
Inhibitors of the BMP signaling pathway
|
|
EP2283119B1
(en)
|
2008-05-06 |
2015-01-07 |
Joslin Diabetes Center, Inc. |
Methods and compositions for inducing brown adipogenesis
|
|
WO2009137075A1
(en)
*
|
2008-05-06 |
2009-11-12 |
Acceleron Pharma Inc. |
Anti-activin antibodies and uses for promoting bone growth
|
|
KR20110031951A
(ko)
|
2008-06-26 |
2011-03-29 |
악셀레론 파마 인코포레이티드 |
액티빈-ａｃｔｒｉｉａ의 길항물질 및 적혈구 수준을 증가시키기 위한 이들의 용도
|
|
WO2009158025A2
(en)
|
2008-06-26 |
2009-12-30 |
Acceleron Pharma Inc. |
Methods for dosing an actriib antagonist and monitoring of treated patients
|
|
TW201919685A
(zh)
|
2008-08-14 |
2019-06-01 |
美商艾瑟勒朗法瑪公司 |
使用ｇｄｆ阱以增加紅血球水平
|
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
|
US20110293526A1
(en)
|
2008-11-20 |
2011-12-01 |
University Of Southern California |
Compositions and methods to modulate hair growth
|
|
MX2011005505A
(es)
|
2008-11-26 |
2011-09-01 |
Amgen Inc |
Variantes de polipeptidos receptores de activina iib y aplicaciones de estos.
|
|
CA2749544A1
(en)
|
2009-01-13 |
2010-07-22 |
Acceleron Pharma Inc. |
Methods for increasing adiponectin
|
|
US8110355B2
(en)
|
2009-02-20 |
2012-02-07 |
GenRemedy, LLC |
Methods for identifying agents that inhibit cell migration, promote cell adhesion and prevent metastasis
|
|
EP3275900A1
(en)
|
2009-04-27 |
2018-01-31 |
Novartis AG |
Compositions and methods for increasing muscle growth
|
|
CA2764890A1
(en)
|
2009-06-08 |
2010-12-16 |
Acceleron Pharma Inc. |
Methods for increasing thermogenic adipocytes
|
|
CN104805105A
(zh)
|
2009-06-12 |
2015-07-29 |
阿塞勒隆制药公司 |
截短的actriib-fc融合蛋白
|
|
RU2642302C1
(ru)
|
2009-08-13 |
2018-01-24 |
Акселерон Фарма Инк. |
Комбинированное применение ловушек gdf и активаторов рецепторов эритропоэтина для повышения содержания эритроцитов
|
|
CA2773494A1
(en)
|
2009-09-09 |
2011-03-17 |
Acceleron Pharma Inc. |
Actriib antagonists and dosing and uses thereof
|
|
ES2869864T3
(es)
|
2009-11-03 |
2021-10-26 |
Acceleron Pharma Inc |
Procedimientos para el tratamiento de la enfermedad del hígado graso
|
|
EP2501400B1
(en)
|
2009-11-17 |
2017-11-01 |
Acceleron Pharma, Inc. |
Actriib proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
|
|
WO2012027065A2
(en)
|
2010-08-27 |
2012-03-01 |
Celgene Corporation |
Combination therapy for treatment of disease
|
|
US8580922B2
(en)
|
2011-03-04 |
2013-11-12 |
Shire Human Genetic Therapies, Inc. |
Peptide linkers for polypeptide compositions and methods for using same
|
|
US9365651B2
(en)
|
2011-07-01 |
2016-06-14 |
Novartis Ag |
Method for treating metabolic disorders by administration of an anti-ActRIIB antibody
|
|
EA202090053A3
(ru)
|
2011-10-17 |
2020-06-30 |
Акселерон Фарма, Инк. |
Способы и композиции для лечения неэффективного эритропоэза
|
|
WO2013063536A1
(en)
|
2011-10-27 |
2013-05-02 |
Acceleron Pharma, Inc. |
Actriib binding agents and uses thereof
|
|
US8765385B2
(en)
|
2011-10-27 |
2014-07-01 |
Ravindra Kumar |
Method of detection of neutralizing anti-actriib antibodies
|
|
BR112014009949A8
(pt)
|
2011-10-28 |
2018-01-16 |
Paranta Biosciences Ltd |
métodos de tratamento de hipersecreção de muco e uso de agentes
|
|
HK1203384A1
(en)
|
2011-12-19 |
2015-12-11 |
Amgen Inc. |
Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof
|
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
|
WO2013186777A2
(en)
|
2012-06-14 |
2013-12-19 |
The Medical Researth, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center |
Use of blocking agents of bone morphogenie protein (bmp) signaling for the treatment of neuroinflammatory and neurodegenerative diseases
|
|
ES2720401T3
(es)
|
2012-07-02 |
2019-07-22 |
Kyowa Hakko Kirin Co Ltd |
Agente terapéutico para la anemia que incluye la anemia renal y la anemia inducida por cáncer que contiene anticuerpo anti-BMP9 como principio activo
|
|
US20150266950A1
(en)
|
2012-10-24 |
2015-09-24 |
Celgene Corporation |
Methods for treating anemia
|
|
US20150276766A1
(en)
|
2012-10-24 |
2015-10-01 |
Celgene Corporation |
Biomarker for use in treating anemia
|
|
WO2014064292A1
(en)
|
2012-10-26 |
2014-05-01 |
Universite Pierre Et Marie Curie (Paris 6) |
A method for preventing or treating atrial fibrillation
|
|
CA2890217C
(en)
|
2012-11-02 |
2021-07-20 |
Yifu FANG |
Activin-actrii antagonists and uses for treating bone and other disorders
|
|
CA2890471C
(en)
|
2012-11-08 |
2021-07-27 |
Clearside Biomedical, Inc. |
Methods and devices for the treatment of ocular diseases in human subjects
|
|
WO2014093531A1
(en)
|
2012-12-11 |
2014-06-19 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Modulation of myofiber repair by anti-myostatin in strategies with stem cells
|
|
US20140220033A1
(en)
|
2013-02-01 |
2014-08-07 |
Santa Maria Biotherapeutics, Inc. |
Administration of an Anti-Activin-A Compound to a Subject
|
|
ES2692363T3
(es)
|
2013-03-14 |
2018-12-03 |
Translate Bio, Inc. |
Composiciones terapéuticas de ARNm y su uso para tratar enfermedades y trastornos
|
|
TWI655207B
(zh)
|
2013-07-30 |
2019-04-01 |
再生元醫藥公司 |
抗活化素ａ之抗體及其用途
|
|
CA2918300A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Methods of treating sporadic inclusion body myositis
|
|
US20160313349A1
(en)
|
2013-12-16 |
2016-10-27 |
Paranta Biosciences Limited |
Method of diagnosis and treatment
|
|
US20160333418A1
(en)
|
2014-01-14 |
2016-11-17 |
Santa Maria Biotherapeutics, Inc. |
Activin Inhibitor Response Prediction and Uses for Treatment
|
|
EP3100056A2
(en)
|
2014-01-27 |
2016-12-07 |
Novartis AG |
Biomarkers predictive of muscle atrophy, method and use
|
|
JP6601687B2
(ja)
|
2014-03-31 |
2019-11-06 |
大日本住友製薬株式会社 |
進行性骨化性線維異形成症の予防剤及び治療剤
|
|
AP2016009549A0
(en)
|
2014-04-18 |
2016-11-30 |
Acceleron Pharma Inc |
Methods for increasing red blood cell levels and treating sickle-cell disease
|
|
TW201622746A
(zh)
|
2014-04-24 |
2016-07-01 |
諾華公司 |
改善或加速髖部骨折術後身體復原之方法
|
|
CN106795224B
(zh)
|
2014-06-04 |
2021-05-18 |
阿塞勒隆制药公司 |
用促滤泡素抑制素多肽治疗病症的方法和组合物
|
|
PE20170471A1
(es)
|
2014-06-13 |
2017-05-14 |
Santa Maria Biotherapeutics Inc |
Polipeptidos receptores formulados y metodos relacionados
|
|
JP6976859B2
(ja)
|
2015-05-13 |
2021-12-08 |
セルジーン コーポレイション |
ＡｃｔＲＩＩリガンドトラップを用いたβ−サラセミアの治療
|