ES2558842T3 - Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad - Google Patents

Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad Download PDF

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Publication number
ES2558842T3
ES2558842T3 ES09800752.9T ES09800752T ES2558842T3 ES 2558842 T3 ES2558842 T3 ES 2558842T3 ES 09800752 T ES09800752 T ES 09800752T ES 2558842 T3 ES2558842 T3 ES 2558842T3
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ES
Spain
Prior art keywords
amino acid
seq
peptide
gip
acid sequence
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ES09800752.9T
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English (en)
Spanish (es)
Inventor
Richard D. Dimarchi
Tao MA
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Indiana University Research and Technology Corp
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Indiana University Research and Technology Corp
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41570802&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2558842(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Indiana University Research and Technology Corp filed Critical Indiana University Research and Technology Corp
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES09800752.9T 2008-06-17 2009-06-16 Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad Active ES2558842T3 (es)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US7327408P 2008-06-17 2008-06-17
US73274P 2008-06-17
US7817108P 2008-07-03 2008-07-03
US78171P 2008-07-03
US9044808P 2008-08-20 2008-08-20
US90448P 2008-08-20
US15134909P 2009-02-10 2009-02-10
US151349P 2009-02-10
PCT/US2009/047447 WO2010011439A2 (en) 2008-06-17 2009-06-16 Gip-based mixed agonists for treatment of metabolic disorders and obesity

Publications (1)

Publication Number Publication Date
ES2558842T3 true ES2558842T3 (es) 2016-02-09

Family

ID=41570802

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09800752.9T Active ES2558842T3 (es) 2008-06-17 2009-06-16 Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad
ES15175377.9T Active ES2650038T3 (es) 2008-06-17 2009-06-16 Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES15175377.9T Active ES2650038T3 (es) 2008-06-17 2009-06-16 Agonistas mixtos a base de GIP para el tratamiento de trastornos metabólicos y obesidad

Country Status (27)

Country Link
US (2) US9062124B2 (enExample)
EP (2) EP2300035B1 (enExample)
JP (2) JP6108659B2 (enExample)
KR (1) KR20110040760A (enExample)
CN (2) CN104945500B (enExample)
AR (1) AR072159A1 (enExample)
AU (1) AU2009274425B2 (enExample)
BR (1) BRPI0915282A2 (enExample)
CA (1) CA2729296A1 (enExample)
CL (1) CL2009001425A1 (enExample)
CO (1) CO6280539A2 (enExample)
CR (1) CR11849A (enExample)
DK (1) DK2300035T3 (enExample)
EA (1) EA020326B9 (enExample)
EC (1) ECSP10010684A (enExample)
ES (2) ES2558842T3 (enExample)
HU (1) HUE028072T2 (enExample)
IL (1) IL209666A (enExample)
MA (1) MA32397B1 (enExample)
MX (1) MX2010013453A (enExample)
NZ (2) NZ589848A (enExample)
PE (1) PE20100056A1 (enExample)
PL (1) PL2300035T3 (enExample)
SG (1) SG192405A1 (enExample)
TW (1) TWI474835B (enExample)
WO (1) WO2010011439A2 (enExample)
ZA (1) ZA201008807B (enExample)

Families Citing this family (138)

* Cited by examiner, † Cited by third party
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