AU5518798A - Specific antagonists for glucose-dependent insulinotropic polypeptide (gip) - Google Patents

Specific antagonists for glucose-dependent insulinotropic polypeptide (gip)

Info

Publication number
AU5518798A
AU5518798A AU55187/98A AU5518798A AU5518798A AU 5518798 A AU5518798 A AU 5518798A AU 55187/98 A AU55187/98 A AU 55187/98A AU 5518798 A AU5518798 A AU 5518798A AU 5518798 A AU5518798 A AU 5518798A
Authority
AU
Australia
Prior art keywords
gip
glucose
specific antagonists
dependent insulinotropic
insulinotropic polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU55187/98A
Inventor
Linda Neville
Chi-Chuan Tseng
Michael M. Wolfe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston University
Original Assignee
Boston University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston University filed Critical Boston University
Publication of AU5518798A publication Critical patent/AU5518798A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU55187/98A 1996-12-03 1997-12-03 Specific antagonists for glucose-dependent insulinotropic polypeptide (gip) Abandoned AU5518798A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3232996P 1996-12-03 1996-12-03
US60032329 1996-12-03
PCT/US1997/022418 WO1998024464A1 (en) 1996-12-03 1997-12-03 Specific antagonists for glucose-dependent insulinotropic polypeptide (gip)

Publications (1)

Publication Number Publication Date
AU5518798A true AU5518798A (en) 1998-06-29

Family

ID=21864358

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55187/98A Abandoned AU5518798A (en) 1996-12-03 1997-12-03 Specific antagonists for glucose-dependent insulinotropic polypeptide (gip)

Country Status (2)

Country Link
AU (1) AU5518798A (en)
WO (1) WO1998024464A1 (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6294899A (en) * 1998-10-07 2000-04-26 Medical College Of Georgia Research Institute, Inc. Glucose-dependent insulinotropic peptide for use as an osteotropic hormone
CA2417590C (en) * 2000-05-16 2009-08-11 Sanwa Kagaku Kenkyusho Co., Ltd Prophylactic or ameliorative agent for insulin resistance and/or obesity
EP1515746A2 (en) * 2002-06-11 2005-03-23 Eisai Co. Ltd Use of compounds having gip activity for the treatment of disorders associated with abnormal loss of cells and/or for the treatment of obesity
WO2003105760A2 (en) * 2002-06-15 2003-12-24 Enteromed, Inc. Prevention and treatment of nonalcoholic fatty liver disease (nafld) by antagonism of the receptor to glucose-dependent insulinotropic polypeptide (gip)
AU2006213607A1 (en) 2005-02-11 2006-08-17 Amylin Pharmaceuticals, Llc GIP analog and hybrid polypeptides with selectable properties
WO2007056362A2 (en) 2005-11-07 2007-05-18 Indiana University Research And Technology Corporation Glucagon analogs exhibiting physiological solubility and stability
EP1857818A1 (en) * 2006-05-15 2007-11-21 DIGILAB BioVisioN GmbH Diagnostic and therapeutic uses of peptides for pre-forms of type 2 diabetes and conditions associated therewith
EP2124974B1 (en) 2007-01-05 2017-03-15 Indiana University Research and Technology Corporation Glucagon analogs exhibiting enhanced solubility in physiological ph buffers
EP2111414B1 (en) 2007-02-15 2014-07-02 Indiana University Research and Technology Corporation Glucagon/glp-1 receptor co-agonists
ES2509883T3 (en) 2007-10-30 2014-10-20 Indiana University Research And Technology Corporation Glucagon antagonists
WO2009058734A1 (en) 2007-10-30 2009-05-07 Indiana University Research And Technology Corporation Compounds exhibiting glucagon antagonist and glp-1 agonist activity
EA019203B9 (en) 2008-06-17 2014-03-31 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Glucagon/glp-1 receptor co-agonists
US9062124B2 (en) 2008-06-17 2015-06-23 Indiana University Research And Technology Corporation GIP-based mixed agonists for treatment of metabolic disorders and obesity
KR20110039230A (en) 2008-06-17 2011-04-15 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 Glucagon analogs exhibiting enhanced solubility and stability in physiological ph buffers
EP2915538A3 (en) * 2008-08-07 2015-10-14 Ipsen Pharma S.A.S. Truncated analogues of glucose-dependent insulinotropic polypeptide
AU2009280017B2 (en) 2008-08-07 2013-01-10 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide
EA020005B1 (en) * 2008-08-07 2014-07-30 Ипсен Фарма С.А.С. Glucose-dependent insulinotropic polypeptide analogues
KR101593158B1 (en) 2008-08-07 2016-02-12 입센 파마 에스.에이.에스. Analogues of glucose-dependent insulinotropic polypeptide (gip) modified at n-terminal
TWI489992B (en) 2008-12-19 2015-07-01 印地安那大學研究及技術公司 Amide based glucagon superfamily peptide prodrugs
MX2011013625A (en) 2009-06-16 2012-01-20 Univ Indiana Res & Tech Corp Gip receptor-active glucagon compounds.
EP2512503A4 (en) 2009-12-18 2013-08-21 Univ Indiana Res & Tech Corp Glucagon/glp-1 receptor co-agonists
MX2012008603A (en) 2010-01-27 2013-01-25 Univ Indiana Res & Tech Corp Glucagon antagonist - gip agonist conjugates and compositions for the treatment of metabolic disorders and obesity.
EP2568993A4 (en) 2010-05-13 2014-02-19 Univ Indiana Res & Tech Corp Glucagon superfamily peptides exhibiting g protein-coupled receptor activity
ES2661228T3 (en) 2010-05-13 2018-03-28 Indiana University Research And Technology Corporation Glucagon superfamily peptides that show nuclear hormone receptor activity
WO2011163012A2 (en) 2010-06-24 2011-12-29 Indiana University Research And Technology Corporation Amide based glucagon superfamily peptide prodrugs
PE20140186A1 (en) 2010-12-22 2014-02-13 Univ Indiana Res & Tech Corp GLUCAGON ANALOGS PRESENTING GIP RECEPTOR ACTIVITY
GEP20176629B (en) 2011-06-22 2017-02-27 Indiana Unversity Research And Tech Corporation Glucagon/glp-1 receptor co-agonists
MX2013015168A (en) 2011-06-22 2014-03-31 Univ Indiana Res & Tech Corp Glucagon/glp-1 receptor co-agonists.
KR20140097151A (en) 2011-11-17 2014-08-06 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 Glucagon superfamily peptides exhibiting glucocorticoid receptor activity
JP6311708B2 (en) 2012-06-21 2018-04-18 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ Glucagon analog showing GIP receptor activity
FR2994848B1 (en) 2012-08-30 2014-08-22 Univ Paris Curie TREATMENT OF ARTHROSIS BY INCRETINED HORMONES OR THEIR ANALOGUES
JP6223376B2 (en) * 2014-03-24 2017-11-01 花王株式会社 Method for evaluating or selecting GIP elevation inhibitor
EP3189072B1 (en) * 2014-09-05 2018-07-18 University of Copenhagen Gip peptide analogues
JP6948330B2 (en) * 2015-12-23 2021-10-13 アムジエン・インコーポレーテツド A method for treating or relieving metabolic disorders using a protein that binds to the gastric inhibitory peptide receptor (GIPR) in combination with a GLP-1 agonist.
JOP20190177A1 (en) 2017-01-17 2019-07-16 Amgen Inc Method of treating or ameliorating metabolic disorders using glp-1 receptor agonists conjugated to antagonists for gastric inhibitory peptide receptor (gipr)
ES2972848T3 (en) 2017-05-31 2024-06-17 The Univ Of Copenhagen Long-acting GIP peptide analogues
PE20200013A1 (en) * 2017-06-20 2020-01-06 Amgen Inc METHOD TO TREAT OR IMPROVE METABOLIC DISORDERS WITH GASTRIC INHIBITOR PEPTIDE RECEPTOR BINDING PROTEINS (GIPR) IN COMBINATION WITH GLP-1 AGONISTS
US20220025010A1 (en) 2018-12-03 2022-01-27 Antag Therapeutics Aps Modified GIP Peptide Analogues

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614492A (en) * 1986-05-05 1997-03-25 The General Hospital Corporation Insulinotropic hormone GLP-1 (7-36) and uses thereof
US5463564A (en) * 1994-09-16 1995-10-31 3-Dimensional Pharmaceuticals, Inc. System and method of automatically generating chemical compounds with desired properties

Also Published As

Publication number Publication date
WO1998024464A1 (en) 1998-06-11

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