ES2437147T3 - Inhibidores de serina proteasa macrocíclicos - Google Patents

Inhibidores de serina proteasa macrocíclicos Download PDF

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Publication number
ES2437147T3
ES2437147T3 ES09707683.0T ES09707683T ES2437147T3 ES 2437147 T3 ES2437147 T3 ES 2437147T3 ES 09707683 T ES09707683 T ES 09707683T ES 2437147 T3 ES2437147 T3 ES 2437147T3
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ES
Spain
Prior art keywords
heterocyclyl
alkyl
aryl
cycloalkyl
heteroaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09707683.0T
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English (en)
Spanish (es)
Inventor
Christophe Claude Parsy
Francois-Rene Alexandre
Dominique Surleraux
Michel Derock
Frederic Leroy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Idenix Pharmaceuticals LLC
Original Assignee
Idenix Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idenix Pharmaceuticals LLC filed Critical Idenix Pharmaceuticals LLC
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Publication of ES2437147T3 publication Critical patent/ES2437147T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
ES09707683.0T 2008-02-04 2009-02-03 Inhibidores de serina proteasa macrocíclicos Active ES2437147T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2608608P 2008-02-04 2008-02-04
US26086P 2008-02-04
US8386708P 2008-07-25 2008-07-25
US83867P 2008-07-25
PCT/US2009/000688 WO2009099596A2 (en) 2008-02-04 2009-02-03 Macrocyclic serine protease inhibitors

Publications (1)

Publication Number Publication Date
ES2437147T3 true ES2437147T3 (es) 2014-01-09

Family

ID=40568607

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09707683.0T Active ES2437147T3 (es) 2008-02-04 2009-02-03 Inhibidores de serina proteasa macrocíclicos

Country Status (21)

Country Link
US (2) US8003659B2 (enExample)
EP (1) EP2250174B1 (enExample)
JP (1) JP5574982B2 (enExample)
KR (1) KR20100118991A (enExample)
CN (1) CN101977915B (enExample)
AR (1) AR070413A1 (enExample)
AU (1) AU2009210789B2 (enExample)
BR (1) BRPI0908021A2 (enExample)
CA (1) CA2712971A1 (enExample)
CO (1) CO6501153A2 (enExample)
CR (1) CR11618A (enExample)
EC (1) ECSP10010413A (enExample)
ES (1) ES2437147T3 (enExample)
IL (1) IL207333A0 (enExample)
MX (1) MX2010008523A (enExample)
NI (1) NI201000136A (enExample)
NZ (1) NZ587133A (enExample)
RU (1) RU2490272C2 (enExample)
TW (1) TW200936131A (enExample)
WO (1) WO2009099596A2 (enExample)
ZA (1) ZA201005318B (enExample)

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