ES2339871T3 - Macrolidos. - Google Patents

Macrolidos. Download PDF

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Publication number
ES2339871T3
ES2339871T3 ES05813939T ES05813939T ES2339871T3 ES 2339871 T3 ES2339871 T3 ES 2339871T3 ES 05813939 T ES05813939 T ES 05813939T ES 05813939 T ES05813939 T ES 05813939T ES 2339871 T3 ES2339871 T3 ES 2339871T3
Authority
ES
Spain
Prior art keywords
alkyl
methyl
substituted
alkoxy
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES05813939T
Other languages
English (en)
Spanish (es)
Inventor
Louis Stanley Chupak
Mark Edward Flanagan
Takushi Kaneko
Thomas Victor Magee
Mark Carl Noe
Usa Reilly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35809765&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2339871(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Application granted granted Critical
Publication of ES2339871T3 publication Critical patent/ES2339871T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Tires In General (AREA)
  • Cephalosporin Compounds (AREA)
ES05813939T 2004-12-21 2005-12-12 Macrolidos. Expired - Lifetime ES2339871T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US63809704P 2004-12-21 2004-12-21
US638097P 2004-12-21
US71753005P 2005-09-14 2005-09-14
US717530P 2005-09-14

Publications (1)

Publication Number Publication Date
ES2339871T3 true ES2339871T3 (es) 2010-05-26

Family

ID=35809765

Family Applications (1)

Application Number Title Priority Date Filing Date
ES05813939T Expired - Lifetime ES2339871T3 (es) 2004-12-21 2005-12-12 Macrolidos.

Country Status (35)

Country Link
US (1) US7462600B2 (de)
EP (2) EP1836211B1 (de)
JP (1) JP4111994B1 (de)
KR (1) KR100897678B1 (de)
CN (1) CN101120011A (de)
AP (1) AP2007004026A0 (de)
AR (1) AR052824A1 (de)
AT (1) ATE459633T1 (de)
AU (1) AU2005317735B2 (de)
BR (1) BRPI0519135A2 (de)
CA (1) CA2591746A1 (de)
CR (1) CR9202A (de)
DE (1) DE602005019786D1 (de)
DK (1) DK1836211T3 (de)
EA (1) EA011281B1 (de)
ES (1) ES2339871T3 (de)
GE (1) GEP20094834B (de)
GT (1) GT200500378A (de)
HN (1) HN2005036113A (de)
HR (1) HRP20100253T1 (de)
IL (1) IL183661A0 (de)
MA (1) MA29108B1 (de)
MX (1) MX2007007598A (de)
NL (1) NL1030713C2 (de)
NO (1) NO20073367L (de)
PE (1) PE20060948A1 (de)
PL (1) PL1836211T3 (de)
PT (1) PT1836211E (de)
SI (1) SI1836211T1 (de)
TN (1) TNSN07233A1 (de)
TW (1) TW200626608A (de)
UA (1) UA85937C2 (de)
UY (1) UY29285A1 (de)
WO (1) WO2006067589A1 (de)
ZA (1) ZA200705108B (de)

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US9133212B1 (en) 2005-06-15 2015-09-15 Vanderbilt University Inhibitors of hemeprotein-catalyzed lipid peroxidation
US8367669B2 (en) * 2005-06-15 2013-02-05 Vanderbilt University Inhibitors of hemeprotein-catalyzed lipid peroxidation
WO2007025098A2 (en) 2005-08-24 2007-03-01 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
JP4468487B1 (ja) * 2007-03-13 2010-05-26 ファイザー・プロダクツ・インク エリスロマイシンをベースとするマクロライド
EP2136806A4 (de) * 2007-03-21 2011-11-23 Creative Antibiotics Sweden Ab Verfahren und mittel zur prävention und unterdrückung von typ iii sekretion bei infektionen durch gram-negative bakterien
US9453042B2 (en) 2007-10-25 2016-09-27 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
WO2009053259A1 (en) * 2007-10-25 2009-04-30 Sandoz Ag Process for the production of telithromycin
CN101903382B (zh) 2007-12-21 2012-11-28 弗·哈夫曼-拉罗切有限公司 杂环抗病毒化合物
US8865662B2 (en) 2009-08-13 2014-10-21 Basilea Pharmaceutica Ag Macrolides and their use
JP5711352B2 (ja) * 2010-03-22 2015-04-30 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライドの結晶形、およびその使用
CN106974913A (zh) * 2011-04-12 2017-07-25 美国卫生和人力服务部 用于治疗或预防疟疾的疟原虫表面阴离子通道抑制剂
CN102558047B (zh) * 2011-12-14 2013-10-30 天津药物研究院药业有限责任公司 3-甲基喹啉的制备方法
IN2014DN08939A (de) 2012-03-27 2015-05-22 Cempra Pharmaceuticals Inc
US9611224B2 (en) 2012-07-13 2017-04-04 Hoffmann-La Roche Inc. Antiproliferative benzo [B] azepin-2-ones
KR101663864B1 (ko) * 2013-04-19 2016-10-07 영남대학교 산학협력단 아미도피리딘올 유도체 또는 이의 약제학적 허용가능한 염을 유효성분으로 함유하는 염증성 장질환의 예방 또는 치료용 약학조성물
TW201534586A (zh) 2013-06-11 2015-09-16 Orion Corp 新穎ｃｙｐ１７抑制劑／抗雄激素劑
CN103739643A (zh) * 2013-12-30 2014-04-23 华东理工大学 利用分子印迹技术对红霉素进行回收分离纯化的方法
CN104230891B (zh) * 2014-08-27 2016-03-30 于宗光 一种托匹司他的制备方法
JP2019533669A (ja) 2016-10-04 2019-11-21 バイオファーマティ ソシエテ アノニム 抗菌活性を有するケトライド
AU2020286381C1 (en) 2019-06-04 2025-07-10 Hager Biosciences, Llc Imidazolo derivatives, compositions and methods as orexin antagonists
AU2020288559C1 (en) * 2019-06-04 2025-07-24 Hager Biosciences, Llc Pyrazole and imidazole derivatives, compositions and methods as orexin antagonists
CN111793022A (zh) * 2020-04-27 2020-10-20 滁州拜奥生物科技有限公司 一种3-甲基喹啉的制备方法
JP2025530768A (ja) * 2022-09-01 2025-09-17 ヘイガー バイオサイエンシズ，エルエルシー 神経疾患および精神疾患の治療のための、オレキシン受容体およびカッパオピオイド受容体に対する二重調節剤としてのピラゾール誘導体およびイミダゾール誘導体、組成物、ならびに治療法

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Also Published As

Publication number Publication date
CA2591746A1 (en) 2006-06-29
ATE459633T1 (de) 2010-03-15
US20060135447A1 (en) 2006-06-22
DE602005019786D1 (de) 2010-04-15
AP2007004026A0 (en) 2007-06-30
GT200500378A (es) 2006-11-28
IL183661A0 (en) 2007-09-20
TNSN07233A1 (fr) 2008-11-21
AR052824A1 (es) 2007-04-04
KR100897678B1 (ko) 2009-05-14
AU2005317735B2 (en) 2009-06-04
MA29108B1 (fr) 2007-12-03
PL1836211T3 (pl) 2010-07-30
TW200626608A (en) 2006-08-01
DK1836211T3 (da) 2010-05-17
NL1030713A1 (nl) 2006-06-22
EA200701113A1 (ru) 2007-12-28
WO2006067589A1 (en) 2006-06-29
HRP20100253T1 (hr) 2010-06-30
PE20060948A1 (es) 2006-10-11
MX2007007598A (es) 2007-07-25
KR20070089191A (ko) 2007-08-30
AU2005317735A1 (en) 2006-06-29
JP2008524319A (ja) 2008-07-10
NO20073367L (no) 2007-09-05
CR9202A (es) 2007-07-16
UA85937C2 (uk) 2009-03-10
BRPI0519135A2 (pt) 2008-12-23
EP2233493A1 (de) 2010-09-29
SI1836211T1 (sl) 2010-04-30
ZA200705108B (en) 2009-01-28
PT1836211E (pt) 2010-04-08
US7462600B2 (en) 2008-12-09
UY29285A1 (es) 2006-07-31
EP1836211B1 (de) 2010-03-03
CN101120011A (zh) 2008-02-06
EA011281B1 (ru) 2009-02-27
GEP20094834B (en) 2009-11-25
NL1030713C2 (nl) 2006-12-12
HN2005036113A (es) 2010-12-06
JP4111994B1 (ja) 2008-07-02
EP1836211A1 (de) 2007-09-26

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