EP2017663A3 - Objektiv für ein Immersionsmikroskop und Laserabtastungs-Mikroskopsystem damit - Google Patents
Objektiv für ein Immersionsmikroskop und Laserabtastungs-Mikroskopsystem damit Download PDFInfo
- Publication number
- EP2017663A3 EP2017663A3 EP08012853A EP08012853A EP2017663A3 EP 2017663 A3 EP2017663 A3 EP 2017663A3 EP 08012853 A EP08012853 A EP 08012853A EP 08012853 A EP08012853 A EP 08012853A EP 2017663 A3 EP2017663 A3 EP 2017663A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- lens
- laser scanning
- refractive power
- lens group
- concave
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B15/00—Optical objectives with means for varying the magnification
- G02B15/14—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective
- G02B15/145—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective having five groups only
- G02B15/1451—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective having five groups only the first group being positive
- G02B15/145119—Optical objectives with means for varying the magnification by axial movement of one or more lenses or groups of lenses relative to the image plane for continuously varying the equivalent focal length of the objective having five groups only the first group being positive arranged ++--+
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/02—Objectives
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/33—Immersion oils, or microscope systems or objectives for use with immersion fluids
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B9/00—Optical objectives characterised both by the number of the components and their arrangements according to their sign, i.e. + or -
- G02B9/60—Optical objectives characterised both by the number of the components and their arrangements according to their sign, i.e. + or - having five components only
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Lenses (AREA)
- Microscoopes, Condenser (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12008380.3A EP2573608B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
| EP12008381.1A EP2573609B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007186369 | 2007-07-17 | ||
| JP2008138231 | 2008-05-27 | ||
| JP2008179449A JP5536995B2 (ja) | 2007-07-17 | 2008-07-09 | 顕微鏡対物レンズおよびレーザー走査型顕微鏡システム |
Related Child Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP12008381.1A Division-Into EP2573609B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
| EP12008381.1A Division EP2573609B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
| EP12008380.3A Division-Into EP2573608B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
| EP12008380.3A Division EP2573608B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP2017663A2 EP2017663A2 (de) | 2009-01-21 |
| EP2017663A3 true EP2017663A3 (de) | 2012-07-11 |
| EP2017663B1 EP2017663B1 (de) | 2014-10-01 |
Family
ID=39967889
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP12008381.1A Revoked EP2573609B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
| EP08012853.1A Revoked EP2017663B1 (de) | 2007-07-17 | 2008-07-16 | Objektiv für ein Immersionsmikroskop und Laserabtastungs-Mikroskopsystem damit |
| EP12008380.3A Active EP2573608B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP12008381.1A Revoked EP2573609B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP12008380.3A Active EP2573608B1 (de) | 2007-07-17 | 2008-07-16 | Immersionsmikroskopobjektiv und Laserrastermikroskopsystem damit |
Country Status (3)
| Country | Link |
|---|---|
| US (3) | US7869132B2 (de) |
| EP (3) | EP2573609B1 (de) |
| JP (1) | JP5536995B2 (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5309867B2 (ja) * | 2008-10-14 | 2013-10-09 | 株式会社ニコン | 非線形光学顕微鏡及びその調整方法 |
| EP2494399B1 (de) * | 2009-10-29 | 2025-12-03 | California Institute of Technology | Mikroskop mit mehrfachphotonen-erregungslichtfolienbeleuchtung |
| US8634131B2 (en) * | 2009-12-14 | 2014-01-21 | Intelligent Imaging Innovations, Inc. | Spherical aberration correction for non-descanned applications |
| WO2012002542A1 (ja) * | 2010-07-01 | 2012-01-05 | 株式会社ニコン | 光学部材および顕微鏡 |
| WO2012027542A2 (en) | 2010-08-25 | 2012-03-01 | California Institute Of Technology | Simultaneous orthogonal light sheet microscopy and computed optical tomography |
| JP5926914B2 (ja) * | 2010-11-10 | 2016-05-25 | オリンパス株式会社 | 液浸顕微鏡対物レンズ |
| JP5730671B2 (ja) * | 2011-05-31 | 2015-06-10 | オリンパス株式会社 | ズーム結像光学系、及び、それを備えた顕微鏡 |
| JP5839897B2 (ja) * | 2011-09-02 | 2016-01-06 | オリンパス株式会社 | 非線形光学顕微鏡 |
| JP5885537B2 (ja) * | 2012-02-28 | 2016-03-15 | オリンパス株式会社 | 顕微鏡対物レンズ |
| JP5988629B2 (ja) | 2012-03-14 | 2016-09-07 | オリンパス株式会社 | 複数の光学ユニットを備えた顕微鏡 |
| JPWO2013145836A1 (ja) * | 2012-03-30 | 2015-12-10 | ソニー株式会社 | マイクロチップ型光学測定装置及び該装置における光学位置調整方法 |
| WO2014014805A1 (en) * | 2012-07-16 | 2014-01-23 | Trustees Of Boston University | Solid immersion microscopy system with deformable mirror for correction of aberrations |
| JP5993250B2 (ja) * | 2012-08-29 | 2016-09-14 | オリンパス株式会社 | 液浸顕微鏡対物レンズ及びそれを用いた顕微鏡 |
| JP6274952B2 (ja) * | 2013-04-24 | 2018-02-07 | オリンパス株式会社 | 液浸顕微鏡対物レンズ及びそれを用いた顕微鏡 |
| JP6377319B2 (ja) * | 2013-05-24 | 2018-08-22 | 株式会社タムロン | ズームレンズ及び撮像装置 |
| JP2015045773A (ja) * | 2013-08-29 | 2015-03-12 | 富士フイルム株式会社 | 走査光学系、光走査装置および放射線画像読取装置 |
| JP6184287B2 (ja) * | 2013-10-17 | 2017-08-23 | オリンパス株式会社 | 液浸系顕微鏡対物レンズ及びそれを用いた顕微鏡 |
| JP6223115B2 (ja) * | 2013-10-18 | 2017-11-01 | オリンパス株式会社 | 液浸顕微鏡対物レンズ及びそれを用いた顕微鏡 |
| EP3087423B1 (de) * | 2013-12-24 | 2025-12-10 | Tissuevision, Inc. | Multifokale multiphotonbildgebungssysteme und verfahren |
| CN105445824B (zh) * | 2014-08-20 | 2017-02-22 | 清华大学 | Led光通信接收透镜及led光通信系统 |
| KR20170059475A (ko) * | 2014-09-29 | 2017-05-30 | 에이에스엠엘 홀딩 엔.브이. | 고 개구수 대물 렌즈 시스템 |
| US10018817B2 (en) * | 2015-03-04 | 2018-07-10 | Aramco Services Company | Adaptive optics for imaging through highly scattering media in oil reservoir applications |
| US10788403B2 (en) | 2015-03-11 | 2020-09-29 | Tissuevision, Inc. | Systems and methods for serial staining and imaging |
| KR102047429B1 (ko) * | 2015-12-07 | 2019-11-21 | 에이에스엠엘 홀딩 엔.브이. | 대물렌즈 시스템 |
| DE102016212020A1 (de) * | 2016-07-01 | 2018-01-04 | Carl Zeiss Microscopy Gmbh | Anordnung zur Mikroskopie und zur Korrektur von Aberrationen |
| JP6906923B2 (ja) | 2016-10-20 | 2021-07-21 | オリンパス株式会社 | 液浸系対物レンズ |
| JP2018066912A (ja) | 2016-10-20 | 2018-04-26 | オリンパス株式会社 | 対物レンズ |
| EP3542142A1 (de) | 2016-11-18 | 2019-09-25 | Tissuevision, Inc. | Systeme und verfahren zur automatisierten gewebeabschnittserfassung, indexierung und -aufbewahrung |
| DE102017108595B3 (de) * | 2017-04-21 | 2018-05-09 | Leica Microsystems Cms Gmbh | Immersionsobjektiv für ein Mikroskop |
| DE102017108593B4 (de) * | 2017-04-21 | 2019-03-14 | Leica Microsystems Cms Gmbh | Korrektionsobjektiv für ein Mikroskop, Immersionsobjektiv und Mikroskop |
| DE102017208615A1 (de) | 2017-05-22 | 2018-11-22 | Carl Zeiss Microscopy Gmbh | Verfahren und Adapter zur Adaption eines Mikroskopobjektivs an ein Digitalmikroskop |
| JP7014891B2 (ja) * | 2018-03-30 | 2022-02-01 | 株式会社ニコン | 眼科装置及び眼科光学系 |
| JP2019191274A (ja) * | 2018-04-19 | 2019-10-31 | オリンパス株式会社 | 撮像光学系、及び、顕微鏡システム |
| JP2019191272A (ja) | 2018-04-19 | 2019-10-31 | オリンパス株式会社 | 液浸系の顕微鏡対物レンズ |
| JP2019191273A (ja) * | 2018-04-19 | 2019-10-31 | オリンパス株式会社 | 対物レンズ |
| DE102019204285A1 (de) | 2019-03-27 | 2020-10-01 | Carl Zeiss Microscopy Gmbh | Objektiv für ein Mikroskop |
| CN110262025B (zh) * | 2019-07-01 | 2024-07-02 | 达科为(深圳)医疗设备有限公司 | 一种数字化病理成像设备 |
| DE102020108333B3 (de) | 2020-03-26 | 2021-07-15 | Technische Universität Ilmenau | Verfahren und Vorrichtung zur Kompensation von instationären Aberrationen bei der konfokalen Vermessung einer Probenoberfläche |
| EP3936922B1 (de) * | 2020-07-10 | 2022-12-21 | Leica Microsystems CMS GmbH | Immersions-mikroskop und verfahren zur erzeugung eines übersichtsbildes einer probe |
| CN113376810B (zh) * | 2021-06-29 | 2025-03-18 | 江西欧菲光学有限公司 | 光学系统、取像模组及电子设备 |
| JPWO2023002788A1 (de) * | 2021-07-21 | 2023-01-26 | ||
| CN114185151B (zh) * | 2021-12-01 | 2024-04-30 | 苏州中科全象智能科技有限公司 | 一种具有长入瞳距的双波段像方远心扫描物镜 |
| CN115452783B (zh) * | 2022-08-22 | 2023-12-22 | 深圳赛陆医疗科技有限公司 | 检测装置及基因测序仪 |
| CN115308892B (zh) * | 2022-08-26 | 2025-10-03 | 深圳市中图仪器股份有限公司 | 共聚焦显微镜的管镜的光学系统 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5502596A (en) * | 1992-11-20 | 1996-03-26 | Olympus Optical Co., Ltd. | Immersion microscope objective |
| US5517360A (en) * | 1993-07-19 | 1996-05-14 | Olympus Optical Co., Ltd. | Immersion microscope objective |
| JP2002350734A (ja) * | 2001-05-23 | 2002-12-04 | Olympus Optical Co Ltd | 液浸系顕微鏡対物レンズ |
| US20030043473A1 (en) * | 2001-06-29 | 2003-03-06 | Nikon Corporation | Liquid immersion type microscope objective lens |
| JP2007121338A (ja) * | 2005-10-25 | 2007-05-17 | Olympus Corp | 液浸系顕微鏡対物レンズ |
| US20070109659A1 (en) * | 1999-12-29 | 2007-05-17 | Carl Zeiss Smt Ag | Refractive projection objective for immersion lithography |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3700311A (en) | 1971-11-22 | 1972-10-24 | American Optical Corp | Eight component 100x microscope objective |
| US4373785A (en) | 1981-04-22 | 1983-02-15 | Warner Lambert Technologies, Inc. | Microscope objective |
| JPH07117647B2 (ja) * | 1992-05-25 | 1995-12-18 | シーメンス アクチエンゲゼルシヤフト | 走査対物レンズ |
| JP3299808B2 (ja) * | 1993-03-29 | 2002-07-08 | オリンパス光学工業株式会社 | 液浸系顕微鏡対物レンズ |
| JPH07230038A (ja) * | 1994-02-17 | 1995-08-29 | Nikon Corp | 顕微鏡対物レンズ |
| JP3457992B2 (ja) | 1994-04-13 | 2003-10-20 | オリンパス光学工業株式会社 | 液浸系顕微鏡対物レンズ |
| JPH08292373A (ja) * | 1995-04-21 | 1996-11-05 | Olympus Optical Co Ltd | 液浸系顕微鏡対物レンズ |
| US5646411A (en) * | 1996-02-01 | 1997-07-08 | Molecular Dynamics, Inc. | Fluorescence imaging system compatible with macro and micro scanning objectives |
| JPH10274742A (ja) | 1997-01-28 | 1998-10-13 | Nikon Corp | 液浸系顕微鏡対物レンズ |
| US6562128B1 (en) * | 2001-11-28 | 2003-05-13 | Seh America, Inc. | In-situ post epitaxial treatment process |
| JP3283499B2 (ja) | 1999-03-18 | 2002-05-20 | オリンパス光学工業株式会社 | レーザ顕微鏡 |
| JP4754675B2 (ja) | 2000-07-14 | 2011-08-24 | オリンパス株式会社 | 顕微鏡対物レンズ |
| JP4692698B2 (ja) * | 2000-11-14 | 2011-06-01 | 株式会社ニコン | 液浸系顕微鏡対物レンズ |
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| JP4751533B2 (ja) | 2001-07-16 | 2011-08-17 | オリンパス株式会社 | 顕微鏡用液浸レンズ |
| JP4082015B2 (ja) * | 2001-10-17 | 2008-04-30 | 株式会社ニコン | 液浸系顕微鏡対物レンズ |
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| JP3944099B2 (ja) | 2003-03-07 | 2007-07-11 | オリンパス株式会社 | 液浸系顕微鏡対物レンズ |
| JP4383080B2 (ja) | 2003-04-15 | 2009-12-16 | オリンパス株式会社 | 対物レンズ |
| JP4554174B2 (ja) | 2003-07-09 | 2010-09-29 | オリンパス株式会社 | 顕微鏡システム、顕微鏡の制御方法、及びプログラム |
| JP2005043624A (ja) | 2003-07-28 | 2005-02-17 | Nikon Corp | 顕微鏡制御装置、顕微鏡装置、及び顕微鏡対物レンズ |
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| US7215478B1 (en) * | 2006-03-06 | 2007-05-08 | Olympus Corporation | Immersion objective optical system |
| JP2008040154A (ja) | 2006-08-07 | 2008-02-21 | Olympus Corp | 共焦点レーザ顕微鏡 |
| JP5112832B2 (ja) * | 2006-12-11 | 2013-01-09 | オリンパス株式会社 | 顕微鏡対物レンズ及びそれを用いた蛍光観察装置 |
| JP4994826B2 (ja) * | 2006-12-25 | 2012-08-08 | オリンパス株式会社 | レーザ顕微鏡 |
| US20090174935A1 (en) * | 2008-01-09 | 2009-07-09 | Szulczewski Michael J | Scanning microscope having complementary, serial scanners |
-
2008
- 2008-07-09 JP JP2008179449A patent/JP5536995B2/ja active Active
- 2008-07-15 US US12/173,111 patent/US7869132B2/en active Active
- 2008-07-16 EP EP12008381.1A patent/EP2573609B1/de not_active Revoked
- 2008-07-16 EP EP08012853.1A patent/EP2017663B1/de not_active Revoked
- 2008-07-16 EP EP12008380.3A patent/EP2573608B1/de active Active
-
2010
- 2010-10-29 US US12/916,240 patent/US8576482B2/en active Active
- 2010-10-29 US US12/916,188 patent/US8508856B2/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5502596A (en) * | 1992-11-20 | 1996-03-26 | Olympus Optical Co., Ltd. | Immersion microscope objective |
| US5517360A (en) * | 1993-07-19 | 1996-05-14 | Olympus Optical Co., Ltd. | Immersion microscope objective |
| US20070109659A1 (en) * | 1999-12-29 | 2007-05-17 | Carl Zeiss Smt Ag | Refractive projection objective for immersion lithography |
| JP2002350734A (ja) * | 2001-05-23 | 2002-12-04 | Olympus Optical Co Ltd | 液浸系顕微鏡対物レンズ |
| US20030043473A1 (en) * | 2001-06-29 | 2003-03-06 | Nikon Corporation | Liquid immersion type microscope objective lens |
| JP2007121338A (ja) * | 2005-10-25 | 2007-05-17 | Olympus Corp | 液浸系顕微鏡対物レンズ |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2573608A2 (de) | 2013-03-27 |
| US20110043906A1 (en) | 2011-02-24 |
| US8576482B2 (en) | 2013-11-05 |
| US20110043924A1 (en) | 2011-02-24 |
| EP2017663B1 (de) | 2014-10-01 |
| EP2573609A2 (de) | 2013-03-27 |
| EP2573608B1 (de) | 2017-08-30 |
| EP2573608A3 (de) | 2013-04-17 |
| US7869132B2 (en) | 2011-01-11 |
| EP2573609B1 (de) | 2017-02-01 |
| EP2017663A2 (de) | 2009-01-21 |
| US20090027769A1 (en) | 2009-01-29 |
| JP5536995B2 (ja) | 2014-07-02 |
| EP2573609A3 (de) | 2013-04-17 |
| JP2010008989A (ja) | 2010-01-14 |
| US8508856B2 (en) | 2013-08-13 |
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