EA201790551A1 - Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору - Google Patents

Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору

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Publication number
EA201790551A1
EA201790551A1 EA201790551A EA201790551A EA201790551A1 EA 201790551 A1 EA201790551 A1 EA 201790551A1 EA 201790551 A EA201790551 A EA 201790551A EA 201790551 A EA201790551 A EA 201790551A EA 201790551 A1 EA201790551 A1 EA 201790551A1
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EA
Eurasian Patent Office
Prior art keywords
methods
compositions
immune responses
transfer vector
reducing immune
Prior art date
Application number
EA201790551A
Other languages
English (en)
Inventor
Такаси Кеи Кисимото
Original Assignee
Селекта Байосайенсиз, Инк.
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Publication date
Application filed by Селекта Байосайенсиз, Инк. filed Critical Селекта Байосайенсиз, Инк.
Publication of EA201790551A1 publication Critical patent/EA201790551A1/ru

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    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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Abstract

Изобретение относится к способам и связанным композициям для введения вирусных трансферных векторов и иммунодепрессантов, направленных на антигенпрезентирующие клетки.
EA201790551A 2014-09-07 2015-09-07 Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору EA201790551A1 (ru)

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US201462047044P 2014-09-07 2014-09-07
US201462047051P 2014-09-07 2014-09-07
US201462047054P 2014-09-07 2014-09-07
US201462047034P 2014-09-07 2014-09-07
US201462051267P 2014-09-16 2014-09-16
US201462051263P 2014-09-16 2014-09-16
US201462051255P 2014-09-16 2014-09-16
US201462051258P 2014-09-16 2014-09-16
US201562101872P 2015-01-09 2015-01-09
US201562101861P 2015-01-09 2015-01-09
US201562101882P 2015-01-09 2015-01-09
US201562101841P 2015-01-09 2015-01-09
PCT/US2015/048771 WO2016037165A1 (en) 2014-09-07 2015-09-07 Methods and compositions for attenuating exon skipping anti-viral transfer vector immune responses

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EA201790551A EA201790551A1 (ru) 2014-09-07 2015-09-07 Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору
EA201790533A EA201790533A1 (ru) 2014-09-07 2015-09-07 Способы и композиции для ослабления иммунных ответов против вирусного вектора для переноса, предназначенного для модулирования экспрессии генов
EA201790532A EA201790532A1 (ru) 2014-09-07 2015-09-07 Способы и композиции для ослабления иммунных ответов против вирусного вектора для переноса
EA201790550A EA201790550A1 (ru) 2014-09-07 2015-09-07 Способы и композиции для ослабления иммунных ответов к корректирущим ген вирусным трансферным векторам
EA201790534A EA201790534A1 (ru) 2014-09-07 2015-09-07 Способы и композиции для ослабления иммунных ответов против вирусного вектора для переноса, предназначенного для генной терапии

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EA201790532A EA201790532A1 (ru) 2014-09-07 2015-09-07 Способы и композиции для ослабления иммунных ответов против вирусного вектора для переноса
EA201790550A EA201790550A1 (ru) 2014-09-07 2015-09-07 Способы и композиции для ослабления иммунных ответов к корректирущим ген вирусным трансферным векторам
EA201790534A EA201790534A1 (ru) 2014-09-07 2015-09-07 Способы и композиции для ослабления иммунных ответов против вирусного вектора для переноса, предназначенного для генной терапии

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