CN106714826A - 用于减弱基因表达调节抗病毒转移载体免疫应答的方法和组合物 - Google Patents
用于减弱基因表达调节抗病毒转移载体免疫应答的方法和组合物 Download PDFInfo
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- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14132—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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Abstract
Description
组# | 免疫接种,i.v.第0天 | NC(i.v.第0天) |
1 | AAV-GFP(1×1010vg) | 无 |
2 | AAV-GFP(1×1010vg) | 50μg的Rapa |
Claims (96)
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PCT/US2015/048770 WO2016037164A1 (en) | 2014-09-07 | 2015-09-07 | Methods and compositions for attenuating gene expression modulating anti-viral transfer vector immune responses |
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CN202111297024.4A Pending CN114146167A (zh) | 2014-09-07 | 2015-09-07 | 用于减弱基因表达调节抗病毒转移载体免疫应答的方法和组合物 |
CN201580047633.0A Pending CN107075499A (zh) | 2014-09-07 | 2015-09-07 | 用于减弱基因编辑抗病毒转移载体免疫应答的方法和组合物 |
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CN201580047634.5A Pending CN107073091A (zh) | 2014-09-07 | 2015-09-07 | 用于减弱外显子跳读抗病毒转移载体免疫应答的方法和组合物 |
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CN202111297024.4A Pending CN114146167A (zh) | 2014-09-07 | 2015-09-07 | 用于减弱基因表达调节抗病毒转移载体免疫应答的方法和组合物 |
CN201580047633.0A Pending CN107075499A (zh) | 2014-09-07 | 2015-09-07 | 用于减弱基因编辑抗病毒转移载体免疫应答的方法和组合物 |
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CN201580047634.5A Pending CN107073091A (zh) | 2014-09-07 | 2015-09-07 | 用于减弱外显子跳读抗病毒转移载体免疫应答的方法和组合物 |
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US (7) | US20160074532A1 (zh) |
EP (5) | EP3193896A4 (zh) |
JP (11) | JP7272746B2 (zh) |
KR (7) | KR20170045346A (zh) |
CN (6) | CN107073050A (zh) |
AU (10) | AU2015311704B2 (zh) |
BR (5) | BR112017001359A2 (zh) |
CA (5) | CA2957808A1 (zh) |
EA (5) | EA201790533A1 (zh) |
IL (10) | IL292575A (zh) |
MX (10) | MX2017002935A (zh) |
WO (5) | WO2016037165A1 (zh) |
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Correction item: Priority Correct: 62/047,051 2014.09.07 US|62/047,034 2014.09.07 US|62/047,044 2014.09.07 US|62/047,054 2014.09.07 US|62/051,267 2014.09.16 US|62/051,263 2014.09.16 US|62/051,258 2014.09.16 US|62/051,255 2014.09.16 US|62/101,872 2015.01.09 US|62/101,882 2015.01.09 US|62/101,861 2015.01.09 US|62/101,841 2015.01.09 US False: 62/047,051 2014.09.07 US|62/047,034 2014.09.07 US|62/047,044 2014.09.07 US|62/047,054 2014.09.07 US|62/051,267 2014.09.16 US|62/051,263 2014.09.16 US|62/051,258 2014.09.16 US|62/051,255 2014.09.16 US|62/101,872 2015.01.09 US|62/101,882 2015.01.09 US Number: 21 Volume: 33 |
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CI02 | Correction of invention patent application |
Correction item: Priority Correct: 62/047,051 2014.09.07 US|62/047,034 2014.09.07 US|62/047,044 2014.09.07|62/047,054 2014.09.07 US|62/051,267 2014.09.16 US|62/051,263 2014.09.16 US|62/051,258 2014.09.16 US|62/051,255 2014.09.16 US|62/101,872 2015.01.09 US|62/101,882 2015.01.09 US|62/101,861 2015.01.09 US|62/101,841 2015.01.09 US False: 62/047,051 2014.09.07 US|62/047,034 2014.09.07 US|62/047,044 2014.09.07|62/047,054 2014.09.07 US|62/051,267 2014.09.16 US|62/051,263 2014.09.16 US|62/051,258 2014.09.16 US|62/051,255 2014.09.16 US|62/101,872 2015.01.09 US|62/101,882 2015.01.09 US Number: 21 Page: The title page Volume: 33 |