EA200602068A1 - Ферментативное получение тонких химических соединений - Google Patents

Ферментативное получение тонких химических соединений

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Publication number
EA200602068A1
EA200602068A1 EA200602068A EA200602068A EA200602068A1 EA 200602068 A1 EA200602068 A1 EA 200602068A1 EA 200602068 A EA200602068 A EA 200602068A EA 200602068 A EA200602068 A EA 200602068A EA 200602068 A1 EA200602068 A1 EA 200602068A1
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EA
Eurasian Patent Office
Prior art keywords
sugar
liquid medium
starch
containing liquid
fermentation
Prior art date
Application number
EA200602068A
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English (en)
Other versions
EA015492B9 (ru
EA015492B1 (ru
Inventor
Маркус Помпеюс
Штефан Фрайер
Маркус Лошайдт
Оскар Цельдер
Маттиас Бой
Original Assignee
Басф Акциенгезелльшафт
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Publication date
Application filed by Басф Акциенгезелльшафт filed Critical Басф Акциенгезелльшафт
Publication of EA200602068A1 publication Critical patent/EA200602068A1/ru
Publication of EA015492B1 publication Critical patent/EA015492B1/ru
Publication of EA015492B9 publication Critical patent/EA015492B9/ru

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    • C12P13/00—Preparation of nitrogen-containing organic compounds
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    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
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    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
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    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/20—Preparation of compounds containing saccharide radicals produced by the action of an exo-1,4 alpha-glucosidase, e.g. dextrose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Abstract

Изобретение относится к способу получения по меньшей мере одного продукта микробиологического обмена веществ, содержащего по меньшей мере 3 атома углерода или по меньшей мере 2 атома углерода и по меньшей мере один атом азота, микробиологической ферментацией с применением сахара, который включает:a) получение сахарсодержащей жидкой среды, содержание моносахарида в которой составляет более 20 вес.%, из источника крахмала, причем сахарсодержащая жидкая среда содержит также не содержащие крахмал твердые компоненты источника крахмала;b) ферментацию сахарсодержащей жидкой среды для получения продукта(ов) обмена веществ иc) обеднение или выделение по меньшей мере одного продукта обмена веществ из ферментационного бульона,причем штамм микроорганизма, продуцирующий желаемый(ые) продукт(ы) обмена веществ, культивируют сахарсодержащей жидкой средой, которую получают:а1) измельчением источника крахмала иа2) растворением измельченного материала в водной жидкости в присутствии по меньшей мере одного фермента, растворяющего крахмал, и дальнейшим засахариванием с применением по меньшей мере одного засахаривающего фермента, причем по меньшей мере одну часть измельченного материала растворяют непрерывным или периодическим добавлением в водную жидкость.
EA200602068A 2004-05-28 2005-05-27 Способ получения по меньшей мере одного продукта микробного метаболизма, содежащего по крайней мере три атома углерода или по крайней мере два атома углерода и по крайней мере один атом азота, путем микробиологической ферментации сахаров и композиция на основе протеинов, полученная данным способом EA015492B9 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004026152A DE102004026152A1 (de) 2004-05-28 2004-05-28 Fermentative Herstellung von Feinchemikalien
PCT/EP2005/005728 WO2005116228A2 (de) 2004-05-28 2005-05-27 Fermentative herstellung von feinchemikalien

Publications (3)

Publication Number Publication Date
EA200602068A1 true EA200602068A1 (ru) 2007-06-29
EA015492B1 EA015492B1 (ru) 2011-08-30
EA015492B9 EA015492B9 (ru) 2012-02-28

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EA200602068A EA015492B9 (ru) 2004-05-28 2005-05-27 Способ получения по меньшей мере одного продукта микробного метаболизма, содежащего по крайней мере три атома углерода или по крайней мере два атома углерода и по крайней мере один атом азота, путем микробиологической ферментации сахаров и композиция на основе протеинов, полученная данным способом

Country Status (18)

Country Link
US (1) US9109244B2 (ru)
EP (1) EP1753868A2 (ru)
JP (1) JP4659825B2 (ru)
KR (2) KR101317064B1 (ru)
CN (1) CN1981045B (ru)
AR (1) AR049122A1 (ru)
AU (1) AU2005248061B2 (ru)
BR (1) BRPI0511601A (ru)
CA (1) CA2566475A1 (ru)
DE (1) DE102004026152A1 (ru)
EA (1) EA015492B9 (ru)
MX (1) MX291201B (ru)
MY (1) MY148904A (ru)
PH (1) PH12006502292B1 (ru)
TW (1) TWI386488B (ru)
UA (1) UA89785C2 (ru)
WO (1) WO2005116228A2 (ru)
ZA (1) ZA200610738B (ru)

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JP4659825B2 (ja) 2011-03-30
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DE102004026152A1 (de) 2005-12-15
TWI386488B (zh) 2013-02-21
EA015492B9 (ru) 2012-02-28
MY148904A (en) 2013-06-14
JP2008500823A (ja) 2008-01-17
AR049122A1 (es) 2006-06-28
AU2005248061A1 (en) 2005-12-08
BRPI0511601A (pt) 2008-01-02
WO2005116228A3 (de) 2006-05-11
US9109244B2 (en) 2015-08-18
KR20070021226A (ko) 2007-02-22
EP1753868A2 (de) 2007-02-21
UA89785C2 (ru) 2010-03-10
KR101317064B1 (ko) 2013-10-16
AU2005248061B2 (en) 2010-02-11
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MX291201B (es) 2011-10-20
CN1981045A (zh) 2007-06-13
WO2005116228A8 (de) 2007-03-15
WO2005116228A2 (de) 2005-12-08
US20090162892A1 (en) 2009-06-25
EA015492B1 (ru) 2011-08-30
KR20120101724A (ko) 2012-09-14
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