WO2005116228A8 - Fermentative herstellung von feinchemikalien - Google Patents

Fermentative herstellung von feinchemikalien

Info

Publication number
WO2005116228A8
WO2005116228A8 PCT/EP2005/005728 EP2005005728W WO2005116228A8 WO 2005116228 A8 WO2005116228 A8 WO 2005116228A8 EP 2005005728 W EP2005005728 W EP 2005005728W WO 2005116228 A8 WO2005116228 A8 WO 2005116228A8
Authority
WO
WIPO (PCT)
Prior art keywords
sugar
liquid medium
metabolic product
containing liquid
starch source
Prior art date
Application number
PCT/EP2005/005728
Other languages
English (en)
French (fr)
Other versions
WO2005116228A3 (de
WO2005116228A2 (de
Inventor
Markus Pompejus
Stephan Freyer
Markus Lohscheidt
Oskar Zelder
Matthias Boy
Original Assignee
Basf Ag
Markus Pompejus
Stephan Freyer
Markus Lohscheidt
Oskar Zelder
Matthias Boy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag, Markus Pompejus, Stephan Freyer, Markus Lohscheidt, Oskar Zelder, Matthias Boy filed Critical Basf Ag
Priority to US11/597,782 priority Critical patent/US9109244B2/en
Priority to EP05754405A priority patent/EP1753868A2/de
Priority to UAA200614015A priority patent/UA89785C2/uk
Priority to BRPI0511601-5A priority patent/BRPI0511601A/pt
Priority to CA002566475A priority patent/CA2566475A1/en
Priority to AU2005248061A priority patent/AU2005248061B2/en
Priority to KR1020127020012A priority patent/KR101479583B1/ko
Priority to MXPA06013512 priority patent/MX291201B/es
Priority to KR1020067024942A priority patent/KR101317064B1/ko
Priority to JP2007513814A priority patent/JP4659825B2/ja
Priority to CN2005800224514A priority patent/CN1981045B/zh
Priority to EA200602068A priority patent/EA015492B9/ru
Publication of WO2005116228A2 publication Critical patent/WO2005116228A2/de
Publication of WO2005116228A3 publication Critical patent/WO2005116228A3/de
Publication of WO2005116228A8 publication Critical patent/WO2005116228A8/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/20—Preparation of compounds containing saccharide radicals produced by the action of an exo-1,4 alpha-glucosidase, e.g. dextrose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fodder In General (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zur Herstellung wenigstens eines mikrobiellen Stoffwechselprodukts mit mindestens 3 C-Atomen oder mit mindestens 2 C-Atomen und mindestens 1 N-Atom durch zuckerbasierte mikrobielle Fermentation, umfassend: a) die Herstellung eines zuckerhaltigen Flüssigmediums mit einem Monosaccharidgehalt von mehr als 20 Gew.-% aus einer Stärkequelle, wobei das zuckerhaltige Flüssigmedium auch nicht-stärkehaltige feste Bestandteile der Stärkequelle umfasst; b) die Fermentation des zuckerhaltigen Flüssigmediums zur Produktion des(der) Stoffwechselprodukte(s); und c) Abreicherung oder Isolierung wenigstens eines Stoffwechselprodukts aus der Fermentationsbrühe, wobei man einen das(die) gewünschte(n) Stoffwechselprodukt(e) produzierenden Mikroorganismenstamm mit dem zuckerhaltigen Flüssigmedium kultiviert, welches man erhält durch: a1) Vermahlen der Stärkequelle; und a2) Verflüssigen des Mahlguts in einer wässrigen Flüssigkeit in Gegenwart mindestens eines Stärke verflüssigenden Enzyms und anschließendes Verzuckern unter Verwendung mindestens eines verzuckernden Enzyms, wobei man mindestens eine Teilmenge des Mahlguts durch kontinuierliche oder diskontinuierliche Zugabe zur wässrigen Flüssigkeit verflüssigt.
PCT/EP2005/005728 2004-05-28 2005-05-27 Fermentative herstellung von feinchemikalien WO2005116228A2 (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
US11/597,782 US9109244B2 (en) 2004-05-28 2005-05-27 Fermentative production of fine chemicals
EP05754405A EP1753868A2 (de) 2004-05-28 2005-05-27 Fermentative herstellung von feinchemikalien unter verwendung eines fermentationsmediums, welches verflüssigte und verzuckerte stärke aus einer vermahlenen stärkequelle als zuckerquelle beinhaltet
UAA200614015A UA89785C2 (uk) 2004-05-28 2005-05-27 Спосіб одержання щонайменше одного продукту мікробіологічного обміну речовин та білкова композиція, яку одержують згідно зі способом
BRPI0511601-5A BRPI0511601A (pt) 2004-05-28 2005-05-27 processo para a produção de pelo menos um metabólito microbiano, composição de proteìna, e, uso de um meio liquido contendo açúcar
CA002566475A CA2566475A1 (en) 2004-05-28 2005-05-27 Fermentative production of fine chemicals
AU2005248061A AU2005248061B2 (en) 2004-05-28 2005-05-27 Fermentative production of fine chemicals
KR1020127020012A KR101479583B1 (ko) 2004-05-28 2005-05-27 정밀 화학물질의 발효 제조
MXPA06013512 MX291201B (es) 2004-05-28 2005-05-27 Produccion fermentativa de compuestos quimicos finos.
KR1020067024942A KR101317064B1 (ko) 2004-05-28 2005-05-27 정밀 화학물질의 발효 제조
JP2007513814A JP4659825B2 (ja) 2004-05-28 2005-05-27 ファインケミカルの発酵生産
CN2005800224514A CN1981045B (zh) 2004-05-28 2005-05-27 精细化学品的发酵产生
EA200602068A EA015492B9 (ru) 2004-05-28 2005-05-27 Способ получения по меньшей мере одного продукта микробного метаболизма, содежащего по крайней мере три атома углерода или по крайней мере два атома углерода и по крайней мере один атом азота, путем микробиологической ферментации сахаров и композиция на основе протеинов, полученная данным способом

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004026152A DE102004026152A1 (de) 2004-05-28 2004-05-28 Fermentative Herstellung von Feinchemikalien
DE102004026152.0 2004-05-28

Publications (3)

Publication Number Publication Date
WO2005116228A2 WO2005116228A2 (de) 2005-12-08
WO2005116228A3 WO2005116228A3 (de) 2006-05-11
WO2005116228A8 true WO2005116228A8 (de) 2007-03-15

Family

ID=35404441

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/005728 WO2005116228A2 (de) 2004-05-28 2005-05-27 Fermentative herstellung von feinchemikalien

Country Status (18)

Country Link
US (1) US9109244B2 (de)
EP (1) EP1753868A2 (de)
JP (1) JP4659825B2 (de)
KR (2) KR101317064B1 (de)
CN (1) CN1981045B (de)
AR (1) AR049122A1 (de)
AU (1) AU2005248061B2 (de)
BR (1) BRPI0511601A (de)
CA (1) CA2566475A1 (de)
DE (1) DE102004026152A1 (de)
EA (1) EA015492B9 (de)
MX (1) MX291201B (de)
MY (1) MY148904A (de)
PH (1) PH12006502292B1 (de)
TW (1) TWI386488B (de)
UA (1) UA89785C2 (de)
WO (1) WO2005116228A2 (de)
ZA (1) ZA200610738B (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005042541A1 (de) * 2005-09-07 2007-03-08 Basf Ag Fermentative Herstellung nichtflüchtiger mikrobieller Stoffwechselprodukte in fester Form
DE102005056669A1 (de) 2005-11-28 2007-05-31 Basf Ag Fermentative Herstellung organischer Verbindungen unter Einsatz Dextrin-haltiger Medien
DE102005056668A1 (de) * 2005-11-28 2007-05-31 Basf Ag Fermentative Herstellung organischer Verbindungen
DE102005056667A1 (de) 2005-11-28 2007-05-31 Basf Ag Fermentative Herstellung organischer Verbindungen
EP2049675A1 (de) 2006-08-01 2009-04-22 Basf Se Verfahren zur herstellung von pentamethylen-1,5-diisocyanat
EP2084288A1 (de) 2006-10-31 2009-08-05 Metabolic Explorer Verfahren zur biologischen herstellung von 1,3-propandiol aus glycerin mit hoher ausbeute
WO2008086595A1 (en) * 2007-01-18 2008-07-24 Alternate Energy Corporation Process for manufacturing hydrogen and monosodium glutamate
DK2118276T3 (en) * 2007-02-07 2015-10-12 Danisco Us Inc STARCH HYDROLYSIS BY USING PHYTASE WITH ALPHA-amylase
DE102007017184A1 (de) 2007-04-12 2008-10-16 Evonik Degussa Gmbh Verfahren zur integrierten Verwertung der Energie- und Stoffinhalte von Hydrolysaten
CA2899225A1 (en) 2007-07-06 2009-01-15 Basf Se Method for the production of an aqueous glucose solution
MY153731A (en) * 2007-12-27 2015-03-13 Gevo Inc Recovery of higher alcohols from dilute aqueous solutions
CA2718017C (en) * 2008-03-11 2017-10-10 Danisco Us Inc. Glucoamylase and buttiauxiella phytase during saccharification
US8785154B2 (en) * 2008-04-14 2014-07-22 Basf Se Method for manufacturing an aqueous glucose solution from plants of the Triticeae species
JP5746614B2 (ja) * 2008-04-15 2015-07-08 ザ ユナイテッド ステイツ オブ アメリカ、 アズ リプレゼンティッド バイ ザ セクレタリー オブ アグリカルチャー 澱粉含有穀物から得られる蛋白質濃縮物、その組成、製造方法及び使用
KR101613754B1 (ko) 2008-10-03 2016-04-19 메타볼릭 익스플로러 강하 막, 와이프드 막, 박막 또는 단경로 증발기를 사용한 발효 브로쓰로부터의 알콜의 정제 방법
JP4733731B2 (ja) * 2008-11-11 2011-07-27 三栄レギュレーター株式会社 非食用リグノセルロース系バイオマスの代替燃料製造方法。
JP5735956B2 (ja) * 2009-05-20 2015-06-17 キシレコ インコーポレイテッド バイオマス加工方法
US8636402B2 (en) * 2009-05-20 2014-01-28 Xyleco, Inc. Processing biomass
KR102176554B1 (ko) * 2009-06-04 2020-11-09 게노마티카 인코포레이티드 발효액 성분들의 분리 방법
EP2526182B1 (de) 2010-01-20 2017-08-02 Xyleco, Inc. Dispersion von einsatzstoffe und verarbeitung von materialien
DE102010025167A1 (de) 2010-06-25 2011-12-29 Uhde Gmbh Verfahren zur Abtrennung, Gewinnung und Reinigung von Bernsteinsäure
KR101390254B1 (ko) * 2010-12-24 2014-05-02 한국화학연구원 당수율을 극대화시키는 바이오매스의 처리 방법 및 이에 사용되는 첨가제
DE102011120632A1 (de) 2011-12-09 2013-06-13 Thyssenkrupp Uhde Gmbh Verfahren zur Aufreinigung von Carbonsäuren aus Fermentationsbrühen
CN102925517B (zh) * 2012-10-26 2014-04-23 中国农业科学院生物技术研究所 转植酸酶玉米的用途和制备液化液和糖化液及发酵产品的方法
EP2745905A1 (de) 2012-12-21 2014-06-25 ThyssenKrupp Uhde GmbH Verfahren zur Reinigung von Carboxylsäuren durch subkritische oder superkritische Chromatography
DE102013000027A1 (de) 2013-01-03 2014-07-03 Thyssenkrupp Industrial Solutions Ag Verfahren zur Aufreinigung von Carbonsäuren aus Fermentationsbrühen
WO2014108163A2 (de) 2013-01-11 2014-07-17 Thyssenkrupp Uhde Gmbh Verfahren zur herstellung von dicarbonsäuren
NZ706072A (en) * 2013-03-08 2018-12-21 Xyleco Inc Equipment protecting enclosures
JP6572206B2 (ja) 2013-09-25 2019-09-04 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ ファインケミカルの生産改善のための組換え微生物
CN103710375A (zh) * 2013-12-30 2014-04-09 江南大学 一种用于谷氨酸棒杆菌基因改造的新型质粒及其应用
BR112017006834B1 (pt) 2014-10-02 2022-04-26 Evonik Operations Gmbh Processo para a preparação de um alimento para animais compreendendo pufas, produto extrudado de alimento para animais e método de criação de animais
EP3200603A1 (de) 2014-10-02 2017-08-09 Evonik Degussa GmbH Pufas enthaltendes futtermittel mit hoher abriebfestigkeit und hoher wasserstabilität
BR112017006835A2 (pt) * 2014-10-02 2018-06-19 Evonik Degussa Gmbh método para produzir uma biomassa granular que contém uma substância valiosa sensível à oxidação.
BR112017005388B1 (pt) 2014-10-02 2022-09-13 Evonik Operations Gmbh Alimento para animais contendo biomassa de aurantiochytrium
CA2958457C (en) 2014-10-02 2022-10-25 Evonik Industries Ag Process for producing a pufa-containing biomass which has high cell stability
FR3027821B1 (fr) * 2014-10-31 2018-11-16 Centralesupelec Procede de purification d'oses.
US9394209B2 (en) 2014-12-05 2016-07-19 NutriChem Marketing, Inc. Alternative method for the manufacture of granulated nutrients
US9452968B1 (en) 2015-04-22 2016-09-27 Orochem Technologies, Inc. Separation of adipic acid and dodecanedioic acid from corresponding monoacid and hydroxy acid
CN109803673A (zh) 2016-09-13 2019-05-24 阿勒根公司 非蛋白质梭菌毒素组合物
CN108192944A (zh) * 2018-01-22 2018-06-22 协赛(上海)生物科技有限公司 一种微生物质的生产方法
US11519013B2 (en) * 2018-03-15 2022-12-06 Fluid Quip Technologies, Llc System and method for producing a sugar stream with front end oil separation
CN108374025A (zh) * 2018-06-02 2018-08-07 山东省同泰维润食品科技有限公司 一种丙酸制备工艺
CN111057727B (zh) * 2019-12-16 2021-10-08 新疆阜丰生物科技有限公司 一种生产、分离和提取l-谷氨酰胺的方法
CN113057247B (zh) * 2019-12-31 2024-02-02 丰益(上海)生物技术研发中心有限公司 高起泡性和起泡稳定性大豆蛋白组合物及其制备方法
CN111172204B (zh) * 2020-03-13 2023-01-24 合肥五粮泰生物科技有限公司 一种提高柠檬酸发酵效率的制备方法
US10995351B1 (en) 2020-09-14 2021-05-04 Fluid Quip Technologies, Llc System and method for producing a carbohydrate stream from a cellulosic feedstock
CN113817794B (zh) * 2021-09-30 2023-07-28 四川龙蟒福生科技有限责任公司 一种赤霉酸GA3≧7.5g/L的发酵方法

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3787587A (en) * 1971-12-22 1974-01-22 G Weber Accelerated aging of alcoholic beverages
US4306023A (en) * 1980-02-04 1981-12-15 Robert S. Butler Production of alcohol
JPS5938B2 (ja) 1980-06-03 1984-01-05 味の素株式会社 穀類澱粉の直接糖化方法
JPS57159500A (en) 1981-03-27 1982-10-01 Teijin Eng Preparation of rice starch hydrolysate having good taste
DE3146558A1 (de) 1981-11-24 1983-06-01 Bernhard 4720 Beckum Grosse-Lohmann Verfahren und vorrichtung zum umsetzen von staerkehaltigen produkten zu maischeloesungen
NL8302229A (nl) 1983-06-22 1985-01-16 Avebe Coop Verkoop Prod Werkwijze ter bereiding van aardappelhydrolysaatmateriaal en een door tussenkomst van de werkwijze verkregen produkt.
US4889921A (en) * 1987-04-29 1989-12-26 The University Of Toronto Innovations Foundation Production of rapeseed protein materials
DE4130867A1 (de) 1991-09-17 1993-03-18 Degussa Verfahren zur fermentativen herstellung von aminosaeuren
DE4130868C2 (de) * 1991-09-17 1994-10-13 Degussa Tierfuttermittelsupplement auf der Basis einer Aminosäure und Verfahren zu dessen Herstellung
KR19980702782A (ko) 1995-03-09 1998-08-05 혼 마가렛 에이. 녹말 액화 방법
RU2090614C1 (ru) 1995-03-21 1997-09-20 Государственный научно-исследовательский институт биосинтеза белковых веществ Способ получения белково-витаминного продукта из крахмалсодержащего сырья
DE19519270A1 (de) 1995-05-31 1996-12-05 Berthold Rainer Drucklos arbeitende Stärkeaufschlußanlage
RU2081166C1 (ru) 1995-06-23 1997-06-10 Государственный научно-исследовательский институт биосинтеза белковых веществ Способ получения белкового продукта из крахмал и целлюлозосодержащего растительного сырья
DE19621930C1 (de) 1996-05-31 1997-12-11 Degussa Verfahren zur Herstellung eines Tierfuttermittel-Zusatzes auf Fermentationsbrühe-Basis
IL120923A0 (en) * 1997-05-27 1997-09-30 Amylum Nv A combined process for the production of lysine and its salts and of a further weak acid and a salt thereof
CN1173541A (zh) 1997-08-26 1998-02-18 湖北省广水市民族化工有限公司 高浓度水解糖发酵乳酸的生产方法
CN1067433C (zh) 1997-11-24 2001-06-20 河南莲花味之素有限公司 玉米粗淀粉制糖并进行谷氨酸发酵生产工艺
JP2001072701A (ja) 1999-06-29 2001-03-21 Ajinomoto Co Inc タピオカ澱粉の製造方法及びアミノ酸の発酵生産方法
CN101550410A (zh) * 1999-07-09 2009-10-07 诺维信公司 葡糖淀粉酶变体
CN1077138C (zh) 1999-11-19 2002-01-02 天津市工业微生物研究所 以稻米为原料生产柠檬酸的发酵工艺
US6479700B2 (en) 2000-03-29 2002-11-12 Archer-Daniels-Midland Company Method for separating a basic amino acid from fermentation broth
JP2001275693A (ja) * 2000-03-31 2001-10-09 Ajinomoto Co Inc 高濃度糖液の製造方法並びに当該糖液を用いたアミノ酸の発酵生産方法
JP2001309751A (ja) * 2000-05-02 2001-11-06 Ajinomoto Co Inc 飼料用添加物
CA2422817A1 (en) * 2000-09-20 2003-03-19 Basf Aktiengesellschaft Animal feed supplement containing d-pantothenic acid and/or its salts, improved method for the production thereof, and its use
FR2816321B1 (fr) * 2000-11-09 2003-01-24 Roquette Freres Procede de preparation d'un milieu de fermentation a partir d'une matiere premiere renouvelable
HU227432B1 (hu) * 2001-01-19 2011-06-28 Basf Ag Mikroorganizmusok és eljárások pantotenát fokozott termelésére
EE200100181A (et) 2001-03-23 2002-12-16 L�unat��stuse AS Meetod biolaguneva piimhappepolümeeri saamiseks ja selliselt saadud piimhappepolümeeri kasutamine
DE10118530A1 (de) * 2001-04-14 2002-10-17 Philips Corp Intellectual Pty Plasmabildschirm mit gekippten Entladungselektroden
FR2831552B1 (fr) * 2001-10-30 2004-08-27 Roquette Freres Procede de preparation d'un milieu de fermentation autosuffisant
EP1504109B2 (de) 2002-05-14 2011-05-18 PURAC Biochem BV Verfahren zur herstellung von milchsäure oder deren salz durch gleichzeitige verzuckerung und fermentation von stärke
DK1675941T3 (da) 2003-06-25 2013-08-26 Novozymes As Polypeptider med alfa-amylaseaktivitet og polynukleotider, der koder for dem

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