DK2248807T3 - N-Phenyl-2-pyrimidinaminderivater - Google Patents

N-Phenyl-2-pyrimidinaminderivater

Info

Publication number
DK2248807T3
DK2248807T3 DK10171388.1T DK10171388T DK2248807T3 DK 2248807 T3 DK2248807 T3 DK 2248807T3 DK 10171388 T DK10171388 T DK 10171388T DK 2248807 T3 DK2248807 T3 DK 2248807T3
Authority
DK
Denmark
Prior art keywords
phenyl
pyrimidineamine derivatives
pyrimidineamine
derivatives
Prior art date
Application number
DK10171388.1T
Other languages
English (en)
Inventor
Olivier Loiseleur
Daniel Kaufmann
Stephan Abel
Hans Michael Buerger
Mark Meisenbach
Beat Schmitz
Gottfried Sedelmeier
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK2248807T3 publication Critical patent/DK2248807T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
DK10171388.1T 2002-02-07 2003-02-06 N-Phenyl-2-pyrimidinaminderivater DK2248807T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0202873.6A GB0202873D0 (en) 2002-02-07 2002-02-07 Organic compounds
EP03737319A EP1474408B1 (en) 2002-02-07 2003-02-06 N-phenyl-2-pyrimidine-amine derivatives

Publications (1)

Publication Number Publication Date
DK2248807T3 true DK2248807T3 (da) 2013-08-26

Family

ID=9930607

Family Applications (2)

Application Number Title Priority Date Filing Date
DK10171388.1T DK2248807T3 (da) 2002-02-07 2003-02-06 N-Phenyl-2-pyrimidinaminderivater
DK03737319.8T DK1474408T3 (da) 2002-02-07 2003-02-06 N-Phenyl-2-pyrimidinaminderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK03737319.8T DK1474408T3 (da) 2002-02-07 2003-02-06 N-Phenyl-2-pyrimidinaminderivater

Country Status (26)

Country Link
US (8) US7456283B2 (da)
EP (2) EP1474408B1 (da)
JP (2) JP4653954B2 (da)
KR (1) KR101027044B1 (da)
CN (2) CN101016262A (da)
AU (1) AU2003244444B2 (da)
BR (2) BRPI0307529B1 (da)
CA (2) CA2474738C (da)
CO (1) CO5601018A2 (da)
CY (2) CY1112938T1 (da)
DK (2) DK2248807T3 (da)
EC (2) ECSP045220A (da)
ES (2) ES2384872T3 (da)
GB (1) GB0202873D0 (da)
HK (2) HK1145322A1 (da)
IL (3) IL163158A (da)
MX (1) MXPA04007642A (da)
NO (2) NO327366B1 (da)
NZ (3) NZ569731A (da)
PL (1) PL209475B1 (da)
PT (2) PT1474408E (da)
RU (2) RU2370493C2 (da)
SG (1) SG160195A1 (da)
SI (2) SI2248807T1 (da)
WO (1) WO2003066613A1 (da)
ZA (1) ZA200405970B (da)

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US7550591B2 (en) * 2007-05-02 2009-06-23 Chemagis Ltd. Imatinib production process
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PL215042B1 (pl) * 2008-08-01 2013-10-31 Temapharm Spolka Z Ograniczona Odpowiedzialnoscia Sposób wytwarzania imatinibu
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CN101654416B (zh) * 2009-09-16 2013-06-05 成都神黄医药科技开发有限公司 N-[3-硝基-4-甲基-苯基]-4-醛基-苯甲酰胺及其制备方法以及其衍生物的制备方法
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JP2015522070A (ja) 2012-07-11 2015-08-03 ノバルティス アーゲー 消化管間質腫瘍を治療する方法
CN102827144A (zh) * 2012-09-05 2012-12-19 湖南欧亚生物有限公司 一种伊马替尼的制备方法
RU2537398C1 (ru) * 2013-08-20 2015-01-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный технологический университет" (СибГТУ) Гексазамещенные пара-аминофенолы с ариламидными группами в 2,6-положениях по отношению к гидроксилу
CN103588754B (zh) * 2013-11-04 2015-05-27 遵义医学院 伊马替尼的制备方法
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Also Published As

Publication number Publication date
HK1070893A1 (da) 2005-06-30
KR101027044B1 (ko) 2011-04-11
IL163158A (en) 2010-11-30
US20060142580A1 (en) 2006-06-29
RU2370493C2 (ru) 2009-10-20
ECSP045220A (es) 2004-09-28
IL189657A0 (en) 2008-06-05
US7825247B2 (en) 2010-11-02
US20150018552A1 (en) 2015-01-15
JP2005528340A (ja) 2005-09-22
RU2007148217A (ru) 2009-07-10
US20070293504A1 (en) 2007-12-20
AU2003244444B2 (en) 2007-08-09
AU2003244444A1 (en) 2003-09-02
US7456283B2 (en) 2008-11-25
IL189658A0 (en) 2008-06-05
JP2010138194A (ja) 2010-06-24
KR20040081154A (ko) 2004-09-20
CA2474738C (en) 2011-10-04
ECSP095220A (es) 2009-08-28
RU2004126941A (ru) 2005-10-10
CY1114351T1 (el) 2016-08-31
NZ569731A (en) 2009-11-27
CN1630648A (zh) 2005-06-22
JP4653954B2 (ja) 2011-03-16
NO20091976L (no) 2004-11-05
EP1474408B1 (en) 2012-05-23
NO20043685L (no) 2004-11-05
ES2384872T3 (es) 2012-07-13
CA2474738A1 (en) 2003-08-14
ZA200405970B (en) 2006-05-31
US20070293673A1 (en) 2007-12-20
NO327366B1 (no) 2009-06-15
US20120226039A1 (en) 2012-09-06
SG160195A1 (en) 2010-04-29
BRPI0307529B1 (pt) 2018-01-30
PT2248807E (pt) 2013-09-02
GB0202873D0 (en) 2002-03-27
PT1474408E (pt) 2012-07-25
NZ534315A (en) 2007-06-29
IL189657A (en) 2010-12-30
US7816359B2 (en) 2010-10-19
US7579467B2 (en) 2009-08-25
CA2737565A1 (en) 2003-08-14
CA2737565C (en) 2013-04-09
CY1112938T1 (el) 2016-04-13
CN101016262A (zh) 2007-08-15
US20070293672A1 (en) 2007-12-20
IL189658A (en) 2011-05-31
ES2425980T3 (es) 2013-10-18
NZ554430A (en) 2008-08-29
HK1145322A1 (da) 2011-04-15
EP2248807A1 (en) 2010-11-10
US9573928B2 (en) 2017-02-21
PL209475B1 (pl) 2011-09-30
PL371197A1 (en) 2005-06-13
US20090137805A1 (en) 2009-05-28
DK1474408T3 (da) 2012-06-25
SI2248807T1 (sl) 2013-10-30
SI1474408T1 (sl) 2012-07-31
AU2003244444B9 (en) 2003-09-02
CO5601018A2 (es) 2006-01-31
CN100347162C (zh) 2007-11-07
BR0307529A (pt) 2004-12-21
EP1474408A1 (en) 2004-11-10
EP2248807B1 (en) 2013-07-03
MXPA04007642A (es) 2004-11-10
US20070293683A1 (en) 2007-12-20
WO2003066613A1 (en) 2003-08-14

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