DK175306B1 - Fremgangsmåde til fremstilling af et farmaceutisk granulat - Google Patents

Fremgangsmåde til fremstilling af et farmaceutisk granulat Download PDF

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Publication number
DK175306B1
DK175306B1 DK198900863A DK86389A DK175306B1 DK 175306 B1 DK175306 B1 DK 175306B1 DK 198900863 A DK198900863 A DK 198900863A DK 86389 A DK86389 A DK 86389A DK 175306 B1 DK175306 B1 DK 175306B1
Authority
DK
Denmark
Prior art keywords
therapeutically useful
granulate
useful substance
weight
cellulose
Prior art date
Application number
DK198900863A
Other languages
Danish (da)
English (en)
Other versions
DK86389D0 (da
DK86389A (da
Inventor
Bernardus Leonardus Dijkgraaf
Margaretha Olthoff
Piet Johannes Akkerboom
Original Assignee
Yamanouchi Europ Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv
Publication of DK86389D0 publication Critical patent/DK86389D0/da
Publication of DK86389A publication Critical patent/DK86389A/da
Application granted granted Critical
Publication of DK175306B1 publication Critical patent/DK175306B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK198900863A 1988-02-25 1989-02-24 Fremgangsmåde til fremstilling af et farmaceutisk granulat DK175306B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88200346 1988-02-25
EP88200346 1988-02-25

Publications (3)

Publication Number Publication Date
DK86389D0 DK86389D0 (da) 1989-02-24
DK86389A DK86389A (da) 1989-08-26
DK175306B1 true DK175306B1 (da) 2004-08-16

Family

ID=8199757

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900863A DK175306B1 (da) 1988-02-25 1989-02-24 Fremgangsmåde til fremstilling af et farmaceutisk granulat

Country Status (17)

Country Link
US (1) US5085869A (fr)
EP (1) EP0330284B1 (fr)
JP (1) JP2939262B2 (fr)
KR (1) KR0135289B1 (fr)
CN (1) CN1048395C (fr)
AT (1) ATE108996T1 (fr)
AU (1) AU611999B2 (fr)
CA (1) CA1338553C (fr)
DE (1) DE68916983T2 (fr)
DK (1) DK175306B1 (fr)
ES (1) ES2060737T3 (fr)
FI (1) FI100219B (fr)
IE (1) IE69366B1 (fr)
IL (1) IL89378A (fr)
NO (1) NO178485C (fr)
NZ (1) NZ228122A (fr)
PT (1) PT89823B (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1246188B (it) * 1990-07-27 1994-11-16 Resa Farma Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
GB2257363B (en) * 1991-01-30 1994-09-28 Wellcome Found Water dispersible tablets containing acyclovir
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
JP3069458B2 (ja) * 1992-01-29 2000-07-24 武田薬品工業株式会社 口腔内崩壊型錠剤およびその製造法
ES2111659T3 (es) * 1992-03-11 1998-03-16 Asta Medica Ag Comprimidos, granulados y nodulos con alto contenido en sustancias activas para formas de administracion solidas de alta concentracion.
JP2964195B2 (ja) * 1992-04-28 1999-10-18 エスエス製薬株式会社 ピロキシカム錠及びその製造法
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
IL115445A (en) * 1994-10-17 1999-08-17 Akzo Nobel Nv Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation
SE504902C2 (sv) * 1994-11-02 1997-05-26 Diabact Ab Beredning för påvisande av Helicobacter pylori i magsäcken
ZA961018B (en) * 1995-02-08 1997-08-08 Yamanouchi Europ Bv Oral dosage-forms containing a beta-lactam antibiotic.
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
US5837292A (en) * 1996-07-03 1998-11-17 Yamanouchi Europe B.V. Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug
SK3999A3 (en) * 1996-07-16 1999-07-12 Gist Brocades Nv 'beta'-lactam granules free of organic solvents
PT948318E (pt) * 1996-08-14 2004-06-30 Yamanouchi Europ Bv Granulados compreendendo um composto soluvel em agua e celulose
WO1998036737A1 (fr) * 1997-02-25 1998-08-27 The Procter & Gamble Company Procede de granulation par voie humide
US5785995A (en) * 1997-04-11 1998-07-28 Upsher-Smith Laboratories, Inc. Pharmaceutical tablet of amiodarone salt
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
AU1150799A (en) * 1997-10-10 1999-05-03 Yamanouchi Europe B.V. Oral compositions containing a cephalosporin antibiotic
FR2772617B1 (fr) * 1997-12-19 2001-03-09 Besins Iscovesco Lab Comprime de progesterone et son procede de preparation
ATE354364T1 (de) * 1998-12-23 2007-03-15 Novartis Pharma Gmbh Verwendung von at-1 rezeptorantagonisten oder at- 2 rezeptormodulatoren zur behandlung von erkrankungen, die mit einer erhöhung an at-1 oder at-2 rezeptoren verbunden sind
EA003052B1 (ru) 1999-07-27 2002-12-26 Балканфарма Холдинг АД Антиаритмическое лекарственное средство
GT200100039A (es) * 2000-03-16 2001-12-31 Pfizer Inhibidor de la glucogeno fosforilasa.
HUP0303178A3 (en) * 2001-02-05 2008-03-28 R P Scherer Technologies Methods and compositions for reducing the taste of pharmaceutically active agents
KR20040079967A (ko) * 2002-02-01 2004-09-16 화이자 프로덕츠 인크. 고체 약물 분산액을 함유하는 속방형 제형
US6958161B2 (en) * 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
US20050008691A1 (en) * 2003-05-14 2005-01-13 Arturo Siles Ortega Bicalutamide compositions
MY157620A (en) * 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
GB0714670D0 (en) * 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) * 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
FR2991179B1 (fr) 2012-06-01 2016-11-11 Ceva Sante Animale Compositions veterinaires orales appetentes
US20190167592A1 (en) * 2016-07-13 2019-06-06 Gangwal Chemicals Private Limited Process for directly compressible co-processed excipient for modified release application

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5438167B2 (fr) * 1974-04-27 1979-11-19
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
GB2058565B (en) * 1979-09-21 1983-12-07 Leo Pharm Prod Ltd Layer tablets
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
NZ199931A (en) * 1981-03-13 1985-02-28 Lilly Co Eli Method for formulating medicated animal feed premix comprising a synthetic drug
JPS5839618A (ja) * 1981-09-04 1983-03-08 Chugai Pharmaceut Co Ltd 持続性積層錠剤
EP0080862B1 (fr) * 1981-12-02 1985-09-25 Beecham Group Plc Préparation pharmaceutique contenant des antibiotiques béta-lactame
JPS59101423A (ja) * 1982-12-02 1984-06-12 Takada Seiyaku Kk 新規なニフエジピン固形製剤
JPS6097919A (ja) * 1983-11-01 1985-05-31 Furointo Sangyo Kk 圧縮成形用賦形剤の製造方法
NL8400911A (nl) * 1984-03-22 1985-10-16 Dagra Nv Werkwijze ter bereiding van een farmaceutische toedieningsvorm die tetracycline of doxycyclinezouten bevat.
EP0205336B1 (fr) * 1985-06-11 1991-09-11 Teijin Limited Préparation pharmaceutique orale à effet entretenn
US4753801A (en) * 1985-10-25 1988-06-28 Eli Lilly And Company Sustained release tablets
GB8618811D0 (en) * 1986-08-01 1986-09-10 Approved Prescription Services Sustained release ibuprofen formulation
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds

Also Published As

Publication number Publication date
JPH023606A (ja) 1990-01-09
EP0330284A2 (fr) 1989-08-30
DE68916983T2 (de) 1995-01-19
IE890545L (en) 1989-08-25
FI100219B (fi) 1997-10-31
IL89378A (en) 1993-01-31
NZ228122A (en) 1991-04-26
PT89823A (pt) 1989-10-04
IL89378A0 (en) 1989-09-10
FI890884A (fi) 1989-08-26
KR0135289B1 (ko) 1998-04-23
NO890789D0 (no) 1989-02-24
DK86389D0 (da) 1989-02-24
AU3015889A (en) 1989-08-31
EP0330284B1 (fr) 1994-07-27
NO890789L (no) 1989-08-28
IE69366B1 (en) 1996-09-04
DE68916983D1 (de) 1994-09-01
ATE108996T1 (de) 1994-08-15
KR900012603A (ko) 1990-09-01
NO178485C (no) 1996-04-10
US5085869A (en) 1992-02-04
FI890884A0 (fi) 1989-02-24
ES2060737T3 (es) 1994-12-01
CN1035433A (zh) 1989-09-13
EP0330284A3 (en) 1990-11-07
NO178485B (no) 1996-01-02
PT89823B (pt) 1994-04-29
DK86389A (da) 1989-08-26
AU611999B2 (en) 1991-06-27
CN1048395C (zh) 2000-01-19
CA1338553C (fr) 1996-08-27
JP2939262B2 (ja) 1999-08-25

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