IL89378A - Pharmaceutical granulate having improved flow properties - Google Patents
Pharmaceutical granulate having improved flow propertiesInfo
- Publication number
- IL89378A IL89378A IL89378A IL8937889A IL89378A IL 89378 A IL89378 A IL 89378A IL 89378 A IL89378 A IL 89378A IL 8937889 A IL8937889 A IL 8937889A IL 89378 A IL89378 A IL 89378A
- Authority
- IL
- Israel
- Prior art keywords
- granulate
- flow properties
- improved flow
- pharmaceutical granulate
- wet
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88200346 | 1988-02-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL89378A0 IL89378A0 (en) | 1989-09-10 |
IL89378A true IL89378A (en) | 1993-01-31 |
Family
ID=8199757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL89378A IL89378A (en) | 1988-02-25 | 1989-02-22 | Pharmaceutical granulate having improved flow properties |
Country Status (17)
Country | Link |
---|---|
US (1) | US5085869A (xx) |
EP (1) | EP0330284B1 (xx) |
JP (1) | JP2939262B2 (xx) |
KR (1) | KR0135289B1 (xx) |
CN (1) | CN1048395C (xx) |
AT (1) | ATE108996T1 (xx) |
AU (1) | AU611999B2 (xx) |
CA (1) | CA1338553C (xx) |
DE (1) | DE68916983T2 (xx) |
DK (1) | DK175306B1 (xx) |
ES (1) | ES2060737T3 (xx) |
FI (1) | FI100219B (xx) |
IE (1) | IE69366B1 (xx) |
IL (1) | IL89378A (xx) |
NO (1) | NO178485C (xx) |
NZ (1) | NZ228122A (xx) |
PT (1) | PT89823B (xx) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1246188B (it) * | 1990-07-27 | 1994-11-16 | Resa Farma | Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute. |
PL169106B1 (pl) * | 1991-01-30 | 1996-06-28 | Wellcome Found | Sposób wytwarzania dyspergowalnej w wodzie tabletki PL PL PL PL PL PL PL |
US5629016A (en) * | 1991-01-30 | 1997-05-13 | Glaxo Wellcome Inc. | Water-dispersible tablets |
DE69331839T2 (de) * | 1992-01-29 | 2002-12-12 | Takeda Chemical Industries, Ltd. | Schnellösliche Tablette und ihre Herstellung |
ES2111659T3 (es) * | 1992-03-11 | 1998-03-16 | Asta Medica Ag | Comprimidos, granulados y nodulos con alto contenido en sustancias activas para formas de administracion solidas de alta concentracion. |
JP2964195B2 (ja) * | 1992-04-28 | 1999-10-18 | エスエス製薬株式会社 | ピロキシカム錠及びその製造法 |
GB9215908D0 (en) * | 1992-07-27 | 1992-09-09 | Wellcome Found | Water dispersible tablets |
US5698226A (en) * | 1993-07-13 | 1997-12-16 | Glaxo Wellcome Inc. | Water-dispersible tablets |
IL115445A (en) * | 1994-10-17 | 1999-08-17 | Akzo Nobel Nv | Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation |
SE504902C2 (sv) * | 1994-11-02 | 1997-05-26 | Diabact Ab | Beredning för påvisande av Helicobacter pylori i magsäcken |
EA003736B1 (ru) * | 1995-02-08 | 2003-08-28 | Яманучи Юроп Б.В. | Лекарственная форма для перорального введения, содержащая бета-лактамный антибиотик |
TWI225402B (en) * | 1996-03-13 | 2004-12-21 | Biochemie Gmbh | Auxiliary-free agglomerates |
US5837292A (en) * | 1996-07-03 | 1998-11-17 | Yamanouchi Europe B.V. | Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug |
CN1225583A (zh) * | 1996-07-16 | 1999-08-11 | 吉斯特-布罗卡迪斯有限公司 | 无有机溶剂的β-内酰胺颗粒 |
DE69728290T2 (de) * | 1996-08-14 | 2004-08-05 | Yamanouchi Europe B.V. | Eine wasserlösliche verbindung und cellulose enhaltende granulate |
AU1970797A (en) * | 1997-02-25 | 1998-09-09 | Procter & Gamble Company, The | Wet granulating method |
US5785995A (en) * | 1997-04-11 | 1998-07-28 | Upsher-Smith Laboratories, Inc. | Pharmaceutical tablet of amiodarone salt |
GB9720061D0 (en) | 1997-09-19 | 1997-11-19 | Crosfield Joseph & Sons | Metal compounds as phosphate binders |
WO1999018965A1 (en) * | 1997-10-10 | 1999-04-22 | Yamanouchi Europe B.V. | Oral compositions containing a cephalosporin antibiotic |
FR2772617B1 (fr) * | 1997-12-19 | 2001-03-09 | Besins Iscovesco Lab | Comprime de progesterone et son procede de preparation |
JP2002533390A (ja) * | 1998-12-23 | 2002-10-08 | ノバルティス アクチエンゲゼルシャフト | At−1またはat−2レセプターの増加に関連する疾患の処置のための、at−1レセプターアンタゴニストまたはat−2レセプターモジュレーターの使用 |
EA003052B1 (ru) | 1999-07-27 | 2002-12-26 | Балканфарма Холдинг АД | Антиаритмическое лекарственное средство |
AR028253A1 (es) * | 2000-03-16 | 2003-04-30 | Pfizer Prod Inc | Inhibidores de la glucogeno fosforilasa |
CA2437375A1 (en) * | 2001-02-05 | 2002-08-15 | R.P. Scherer Technologies, Inc. | Methods and compositions for reducing the taste of pharmaceutically active agents |
WO2003063831A2 (en) * | 2002-02-01 | 2003-08-07 | Pfizer Products Inc. | Immediate release dosage forms containing solid drug dispersions |
US6958161B2 (en) * | 2002-04-12 | 2005-10-25 | F H Faulding & Co Limited | Modified release coated drug preparation |
US20050008691A1 (en) * | 2003-05-14 | 2005-01-13 | Arturo Siles Ortega | Bicalutamide compositions |
MY157620A (en) * | 2006-01-31 | 2016-06-30 | Cytochroma Dev Inc | A granular material of a solid water-soluble mixed metal compound capable of binding phosphate |
US8617597B2 (en) | 2006-07-06 | 2013-12-31 | Bayer Intellectual Property Gmbh | Pharmaceutical composition containing a tetrahydrofolic acid |
GB0714670D0 (en) * | 2007-07-27 | 2007-09-05 | Ineos Healthcare Ltd | Use |
GB0720220D0 (en) * | 2007-10-16 | 2007-11-28 | Ineos Healthcare Ltd | Compound |
GB0913525D0 (en) | 2009-08-03 | 2009-09-16 | Ineos Healthcare Ltd | Method |
GB201001779D0 (en) | 2010-02-04 | 2010-03-24 | Ineos Healthcare Ltd | Composition |
FR2991179B1 (fr) | 2012-06-01 | 2016-11-11 | Ceva Sante Animale | Compositions veterinaires orales appetentes |
WO2018011672A1 (en) * | 2016-07-13 | 2018-01-18 | Gangwal Chemicals Private Limited | Process for directly compressible co-processed excipient for modified release application |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5438167B2 (xx) * | 1974-04-27 | 1979-11-19 | ||
JPS5562012A (en) * | 1978-11-06 | 1980-05-10 | Teijin Ltd | Slow-releasing preparation |
GB2058565B (en) * | 1979-09-21 | 1983-12-07 | Leo Pharm Prod Ltd | Layer tablets |
NZ198241A (en) * | 1980-09-27 | 1983-12-16 | Beecham Group Ltd | Tablet containing amoxycillin and potassium clavulanate |
NZ199931A (en) * | 1981-03-13 | 1985-02-28 | Lilly Co Eli | Method for formulating medicated animal feed premix comprising a synthetic drug |
JPS5839618A (ja) * | 1981-09-04 | 1983-03-08 | Chugai Pharmaceut Co Ltd | 持続性積層錠剤 |
DE3266580D1 (en) * | 1981-12-02 | 1985-10-31 | Beecham Group Plc | Pharmaceutical formulation comprising beta-lactam antibiotics |
JPS59101423A (ja) * | 1982-12-02 | 1984-06-12 | Takada Seiyaku Kk | 新規なニフエジピン固形製剤 |
JPS6097919A (ja) * | 1983-11-01 | 1985-05-31 | Furointo Sangyo Kk | 圧縮成形用賦形剤の製造方法 |
NL8400911A (nl) * | 1984-03-22 | 1985-10-16 | Dagra Nv | Werkwijze ter bereiding van een farmaceutische toedieningsvorm die tetracycline of doxycyclinezouten bevat. |
DE3681348D1 (de) * | 1985-06-11 | 1991-10-17 | Teijin Ltd | Oral-arzneizubereitung mit retardwirkung. |
US4753801A (en) * | 1985-10-25 | 1988-06-28 | Eli Lilly And Company | Sustained release tablets |
GB8618811D0 (en) * | 1986-08-01 | 1986-09-10 | Approved Prescription Services | Sustained release ibuprofen formulation |
DE3887179T2 (de) * | 1987-03-02 | 1994-06-16 | Brocades Pharma Bv | Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung. |
US4837031A (en) * | 1987-09-17 | 1989-06-06 | Mallinckrodt, Inc. | Compositions containing ibuprofen |
US4837030A (en) * | 1987-10-06 | 1989-06-06 | American Cyanamid Company | Novel controlled release formulations of tetracycline compounds |
-
1989
- 1989-02-20 ES ES89200430T patent/ES2060737T3/es not_active Expired - Lifetime
- 1989-02-20 EP EP89200430A patent/EP0330284B1/en not_active Expired - Lifetime
- 1989-02-20 DE DE68916983T patent/DE68916983T2/de not_active Expired - Lifetime
- 1989-02-20 AT AT89200430T patent/ATE108996T1/de not_active IP Right Cessation
- 1989-02-21 CA CA000591676A patent/CA1338553C/en not_active Expired - Lifetime
- 1989-02-21 IE IE54589A patent/IE69366B1/en not_active IP Right Cessation
- 1989-02-21 AU AU30158/89A patent/AU611999B2/en not_active Expired
- 1989-02-22 IL IL89378A patent/IL89378A/xx unknown
- 1989-02-24 US US07/315,268 patent/US5085869A/en not_active Expired - Lifetime
- 1989-02-24 NO NO890789A patent/NO178485C/no not_active IP Right Cessation
- 1989-02-24 NZ NZ228122A patent/NZ228122A/xx unknown
- 1989-02-24 DK DK198900863A patent/DK175306B1/da not_active IP Right Cessation
- 1989-02-24 KR KR1019890002201A patent/KR0135289B1/ko not_active IP Right Cessation
- 1989-02-24 PT PT89823A patent/PT89823B/pt not_active IP Right Cessation
- 1989-02-24 FI FI890884A patent/FI100219B/fi not_active IP Right Cessation
- 1989-02-25 CN CN89101157A patent/CN1048395C/zh not_active Expired - Lifetime
- 1989-02-27 JP JP1046330A patent/JP2939262B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5085869A (en) | 1992-02-04 |
KR0135289B1 (ko) | 1998-04-23 |
FI890884A0 (fi) | 1989-02-24 |
KR900012603A (ko) | 1990-09-01 |
JP2939262B2 (ja) | 1999-08-25 |
DE68916983T2 (de) | 1995-01-19 |
NO178485B (no) | 1996-01-02 |
FI890884A (fi) | 1989-08-26 |
AU3015889A (en) | 1989-08-31 |
DE68916983D1 (de) | 1994-09-01 |
CN1048395C (zh) | 2000-01-19 |
AU611999B2 (en) | 1991-06-27 |
NO178485C (no) | 1996-04-10 |
IE69366B1 (en) | 1996-09-04 |
ATE108996T1 (de) | 1994-08-15 |
PT89823B (pt) | 1994-04-29 |
EP0330284B1 (en) | 1994-07-27 |
IE890545L (en) | 1989-08-25 |
DK86389A (da) | 1989-08-26 |
EP0330284A3 (en) | 1990-11-07 |
NO890789L (no) | 1989-08-28 |
DK175306B1 (da) | 2004-08-16 |
EP0330284A2 (en) | 1989-08-30 |
CA1338553C (en) | 1996-08-27 |
NZ228122A (en) | 1991-04-26 |
NO890789D0 (no) | 1989-02-24 |
FI100219B (fi) | 1997-10-31 |
IL89378A0 (en) | 1989-09-10 |
DK86389D0 (da) | 1989-02-24 |
CN1035433A (zh) | 1989-09-13 |
PT89823A (pt) | 1989-10-04 |
ES2060737T3 (es) | 1994-12-01 |
JPH023606A (ja) | 1990-01-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed |