PT89823A - Processo para a preparacao de um granulado farmaceutico com propriedades de fluidez melhoradas - Google Patents

Processo para a preparacao de um granulado farmaceutico com propriedades de fluidez melhoradas

Info

Publication number
PT89823A
PT89823A PT89823A PT8982389A PT89823A PT 89823 A PT89823 A PT 89823A PT 89823 A PT89823 A PT 89823A PT 8982389 A PT8982389 A PT 8982389A PT 89823 A PT89823 A PT 89823A
Authority
PT
Portugal
Prior art keywords
preparing
granulate
improved fluidity
fluidity properties
pharmaceutical granulate
Prior art date
Application number
PT89823A
Other languages
English (en)
Other versions
PT89823B (pt
Inventor
Margaretha Olthoff
Bernardus Leonardus Dijkgraaf
Piet Johannes Akkerboom
Original Assignee
Brocades Pharma Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brocades Pharma Bv filed Critical Brocades Pharma Bv
Publication of PT89823A publication Critical patent/PT89823A/pt
Publication of PT89823B publication Critical patent/PT89823B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT89823A 1988-02-25 1989-02-24 Processo para a preparacao de um granulado farmaceutico com propriedades de fluidez melhoradas PT89823B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88200346 1988-02-25

Publications (2)

Publication Number Publication Date
PT89823A true PT89823A (pt) 1989-10-04
PT89823B PT89823B (pt) 1994-04-29

Family

ID=8199757

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89823A PT89823B (pt) 1988-02-25 1989-02-24 Processo para a preparacao de um granulado farmaceutico com propriedades de fluidez melhoradas

Country Status (17)

Country Link
US (1) US5085869A (pt)
EP (1) EP0330284B1 (pt)
JP (1) JP2939262B2 (pt)
KR (1) KR0135289B1 (pt)
CN (1) CN1048395C (pt)
AT (1) ATE108996T1 (pt)
AU (1) AU611999B2 (pt)
CA (1) CA1338553C (pt)
DE (1) DE68916983T2 (pt)
DK (1) DK175306B1 (pt)
ES (1) ES2060737T3 (pt)
FI (1) FI100219B (pt)
IE (1) IE69366B1 (pt)
IL (1) IL89378A (pt)
NO (1) NO178485C (pt)
NZ (1) NZ228122A (pt)
PT (1) PT89823B (pt)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1246188B (it) * 1990-07-27 1994-11-16 Resa Farma Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composizioni ottenute.
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
EP0522128B1 (en) * 1991-01-30 1996-01-17 The Wellcome Foundation Limited Water-dispersible tablets
JP3069458B2 (ja) * 1992-01-29 2000-07-24 武田薬品工業株式会社 口腔内崩壊型錠剤およびその製造法
DE9321574U1 (de) * 1992-03-11 2000-06-29 Asta Medica Ag Tabletten, Granulate und Pellets mit hohem Gehalt an Wirkstoffen für hochkonzentrierte, feste Darreichungsformen
JP2964195B2 (ja) * 1992-04-28 1999-10-18 エスエス製薬株式会社 ピロキシカム錠及びその製造法
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
IL115445A (en) * 1994-10-17 1999-08-17 Akzo Nobel Nv Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation
SE504902C2 (sv) * 1994-11-02 1997-05-26 Diabact Ab Beredning för påvisande av Helicobacter pylori i magsäcken
PL186386B1 (pl) * 1995-02-08 2004-01-30 Yamanouchi Europ Bv Sposób wytwarzania granulatu zawierającego aktywny przy podawaniu drogą doustną antybiotyk beta-laktamowy oraz sposób wytwarzania szybko rozpadającejsię postaci dawkowania zawierającej aktywny przy podawaniu drogą doustną antybiotyk beta-laktamowy
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
US5837292A (en) * 1996-07-03 1998-11-17 Yamanouchi Europe B.V. Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug
SK3999A3 (en) * 1996-07-16 1999-07-12 Gist Brocades Nv 'beta'-lactam granules free of organic solvents
TR199900296T2 (xx) * 1996-08-14 1999-06-21 Yamanouchi Europe B.V. Suda ��z�n�r bir bile�ik ve sel�loz i�eren gran�ler �r�nler
WO1998036737A1 (en) * 1997-02-25 1998-08-27 The Procter & Gamble Company Wet granulating method
US5785995A (en) * 1997-04-11 1998-07-28 Upsher-Smith Laboratories, Inc. Pharmaceutical tablet of amiodarone salt
GB9720061D0 (en) * 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
AU1150799A (en) * 1997-10-10 1999-05-03 Yamanouchi Europe B.V. Oral compositions containing a cephalosporin antibiotic
FR2772617B1 (fr) * 1997-12-19 2001-03-09 Besins Iscovesco Lab Comprime de progesterone et son procede de preparation
SK9132001A3 (en) * 1998-12-23 2002-01-07 Novartis Ag Use of at-1 receptor antagonist or at-2 receptor modulator for treating diseases associated with an increase of at-1 or at-2 receptors
EA003052B1 (ru) 1999-07-27 2002-12-26 Балканфарма Холдинг АД Антиаритмическое лекарственное средство
GT200100039A (es) * 2000-03-16 2001-12-31 Pfizer Inhibidor de la glucogeno fosforilasa.
JP2004522752A (ja) * 2001-02-05 2004-07-29 アール．ピー． シェーラー テクノロジーズ インコーポレイテッド 薬学的活性剤の味を軽減するための方法および組成物
JP2005517690A (ja) * 2002-02-01 2005-06-16 ファイザー・プロダクツ・インク 固体薬物分散物を含有する即時放出剤形
US6958161B2 (en) * 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
US20050008691A1 (en) * 2003-05-14 2005-01-13 Arturo Siles Ortega Bicalutamide compositions
MY157620A (en) * 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
GB0714670D0 (en) * 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) * 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
FR2991179B1 (fr) * 2012-06-01 2016-11-11 Ceva Sante Animale Compositions veterinaires orales appetentes
US20190167592A1 (en) * 2016-07-13 2019-06-06 Gangwal Chemicals Private Limited Process for directly compressible co-processed excipient for modified release application

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5438167B2 (pt) * 1974-04-27 1979-11-19
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
GB2058565B (en) * 1979-09-21 1983-12-07 Leo Pharm Prod Ltd Layer tablets
NZ198241A (en) * 1980-09-27 1983-12-16 Beecham Group Ltd Tablet containing amoxycillin and potassium clavulanate
NZ199931A (en) * 1981-03-13 1985-02-28 Lilly Co Eli Method for formulating medicated animal feed premix comprising a synthetic drug
JPS5839618A (ja) * 1981-09-04 1983-03-08 Chugai Pharmaceut Co Ltd 持続性積層錠剤
DE3266580D1 (en) * 1981-12-02 1985-10-31 Beecham Group Plc Pharmaceutical formulation comprising beta-lactam antibiotics
JPS59101423A (ja) * 1982-12-02 1984-06-12 Takada Seiyaku Kk 新規なニフエジピン固形製剤
JPS6097919A (ja) * 1983-11-01 1985-05-31 Furointo Sangyo Kk 圧縮成形用賦形剤の製造方法
NL8400911A (nl) * 1984-03-22 1985-10-16 Dagra Nv Werkwijze ter bereiding van een farmaceutische toedieningsvorm die tetracycline of doxycyclinezouten bevat.
EP0205336B1 (en) * 1985-06-11 1991-09-11 Teijin Limited Oral sustained release pharmaceutical preparation
US4753801A (en) * 1985-10-25 1988-06-28 Eli Lilly And Company Sustained release tablets
GB8618811D0 (en) * 1986-08-01 1986-09-10 Approved Prescription Services Sustained release ibuprofen formulation
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds

Also Published As

Publication number Publication date
IL89378A (en) 1993-01-31
DK86389D0 (da) 1989-02-24
NO890789L (no) 1989-08-28
EP0330284A3 (en) 1990-11-07
ATE108996T1 (de) 1994-08-15
JP2939262B2 (ja) 1999-08-25
NO178485C (no) 1996-04-10
CN1048395C (zh) 2000-01-19
FI890884A (fi) 1989-08-26
CN1035433A (zh) 1989-09-13
IE890545L (en) 1989-08-25
DE68916983T2 (de) 1995-01-19
KR0135289B1 (ko) 1998-04-23
CA1338553C (en) 1996-08-27
NO890789D0 (no) 1989-02-24
ES2060737T3 (es) 1994-12-01
KR900012603A (ko) 1990-09-01
EP0330284A2 (en) 1989-08-30
AU611999B2 (en) 1991-06-27
PT89823B (pt) 1994-04-29
DK175306B1 (da) 2004-08-16
IL89378A0 (en) 1989-09-10
DE68916983D1 (de) 1994-09-01
IE69366B1 (en) 1996-09-04
FI100219B (fi) 1997-10-31
US5085869A (en) 1992-02-04
DK86389A (da) 1989-08-26
NO178485B (no) 1996-01-02
AU3015889A (en) 1989-08-31
NZ228122A (en) 1991-04-26
EP0330284B1 (en) 1994-07-27
JPH023606A (ja) 1990-01-09
FI890884A0 (fi) 1989-02-24

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19931008

PD3A Change of proprietorship
MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20090224