DK171990B1 - 1-Heteroaryl-4-((2,5-pyrrolidindion-1-yl)-alkyl)piperazin-derivater, fremgangsmåder til deres fremstilling samt farmaceutiske midler omfattende disse derivater - Google Patents

1-Heteroaryl-4-((2,5-pyrrolidindion-1-yl)-alkyl)piperazin-derivater, fremgangsmåder til deres fremstilling samt farmaceutiske midler omfattende disse derivater Download PDF

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Publication number
DK171990B1
DK171990B1 DK433884A DK433884A DK171990B1 DK 171990 B1 DK171990 B1 DK 171990B1 DK 433884 A DK433884 A DK 433884A DK 433884 A DK433884 A DK 433884A DK 171990 B1 DK171990 B1 DK 171990B1
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formula
compound
acceptable acid
compound according
pyrimidinyl
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DK433884A
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Danish (da)
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DK433884A (da
DK433884D0 (da
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James Stewart New
Joseph P Yevich
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Squibb Bristol Myers Co
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/54—Preparation of carboxylic acid anhydrides
    • C07C51/56—Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/39—Unsaturated compounds containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK433884A 1983-09-12 1984-09-12 1-Heteroaryl-4-((2,5-pyrrolidindion-1-yl)-alkyl)piperazin-derivater, fremgangsmåder til deres fremstilling samt farmaceutiske midler omfattende disse derivater DK171990B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/531,519 US4524206A (en) 1983-09-12 1983-09-12 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US53151983 1983-09-12

Publications (3)

Publication Number Publication Date
DK433884D0 DK433884D0 (da) 1984-09-12
DK433884A DK433884A (da) 1985-03-13
DK171990B1 true DK171990B1 (da) 1997-09-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK433884A DK171990B1 (da) 1983-09-12 1984-09-12 1-Heteroaryl-4-((2,5-pyrrolidindion-1-yl)-alkyl)piperazin-derivater, fremgangsmåder til deres fremstilling samt farmaceutiske midler omfattende disse derivater

Country Status (33)

Country Link
US (1) US4524206A (fr)
JP (1) JPH0647586B2 (fr)
KR (1) KR890000566B1 (fr)
AR (1) AR241910A1 (fr)
AU (1) AU581858B2 (fr)
BE (1) BE900555A (fr)
CA (1) CA1285564C (fr)
CH (1) CH660484A5 (fr)
CS (1) CS258119B2 (fr)
CY (1) CY1538A (fr)
DD (1) DD224593A5 (fr)
DE (1) DE3433327C2 (fr)
DK (1) DK171990B1 (fr)
ES (1) ES8605797A1 (fr)
FI (1) FI83515C (fr)
FR (1) FR2555585B1 (fr)
GB (1) GB2146333B (fr)
GR (1) GR80320B (fr)
HK (1) HK84590A (fr)
HU (1) HU192439B (fr)
IE (1) IE58020B1 (fr)
IL (1) IL72854A (fr)
IT (1) IT1196250B (fr)
LU (1) LU85537A1 (fr)
NL (1) NL8402769A (fr)
NO (1) NO162384B (fr)
NZ (1) NZ209480A (fr)
OA (1) OA07809A (fr)
PT (1) PT79187B (fr)
SE (1) SE463368B (fr)
SU (1) SU1384199A3 (fr)
YU (2) YU45655B (fr)
ZA (1) ZA847065B (fr)

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WO1990002552A1 (fr) * 1988-09-16 1990-03-22 Pfizer Inc. Imides bicycliques polynucleaires de 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butyle a usage antipsychotique
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EP3896058A3 (fr) 2011-10-03 2022-01-12 Syngenta Participations Ag Procédés énantiosélectifs pour des insecticides de pyrrolidines 3-aryl-3-trifluorométhyl-substituées
EP3601275A1 (fr) 2017-03-23 2020-02-05 Syngenta Participations AG Composés insecticides
WO2018172480A1 (fr) 2017-03-23 2018-09-27 Syngenta Participations Ag Composés insecticides
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Also Published As

Publication number Publication date
FR2555585A1 (fr) 1985-05-31
HU192439B (en) 1987-06-29
SE463368B (sv) 1990-11-12
KR890000566B1 (ko) 1989-03-21
YU45809B (sh) 1992-07-20
GB2146333B (en) 1987-04-01
LU85537A1 (fr) 1985-04-29
BE900555A (fr) 1985-03-11
CS258119B2 (en) 1988-07-15
IL72854A (en) 1988-03-31
NZ209480A (en) 1988-01-08
CA1285564C (fr) 1991-07-02
FI83515C (fi) 1991-07-25
DD224593A5 (de) 1985-07-10
FI843522A0 (fi) 1984-09-07
YU45655B (sh) 1992-07-20
JPH0647586B2 (ja) 1994-06-22
US4524206A (en) 1985-06-18
NO162384B (no) 1989-09-11
IE58020B1 (en) 1993-06-30
DE3433327A1 (de) 1985-03-28
IL72854A0 (en) 1984-12-31
YU156384A (en) 1987-02-28
AU3287084A (en) 1985-05-30
ES8605797A1 (es) 1986-04-01
ZA847065B (en) 1985-04-24
IE842311L (en) 1985-03-12
PT79187A (en) 1984-10-01
AU581858B2 (en) 1989-03-09
SE8404552D0 (sv) 1984-09-11
DK433884A (da) 1985-03-13
PT79187B (en) 1986-11-24
ES535780A0 (es) 1986-04-01
NL8402769A (nl) 1985-04-01
HUT36116A (en) 1985-08-28
JPS6084282A (ja) 1985-05-13
IT1196250B (it) 1988-11-16
FI83515B (fi) 1991-04-15
KR850002483A (ko) 1985-05-13
FI843522L (fi) 1985-03-13
FR2555585B1 (fr) 1989-01-06
DK433884D0 (da) 1984-09-12
CS672184A2 (en) 1987-12-17
NO843579L (no) 1985-03-13
HK84590A (en) 1990-10-25
GR80320B (en) 1985-01-14
SE8404552L (sv) 1985-03-13
SU1384199A3 (ru) 1988-03-23
GB2146333A (en) 1985-04-17
DE3433327C2 (de) 1998-07-16
GB8422860D0 (en) 1984-10-17
YU210386A (en) 1987-12-31
OA07809A (fr) 1986-11-20
AR241910A1 (es) 1993-01-29
CY1538A (en) 1990-11-16
IT8422621A0 (it) 1984-09-11
CH660484A5 (de) 1987-04-30

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