DK158727C - 5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem - Google Patents

5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem

Info

Publication number
DK158727C
DK158727C DK340685A DK340685A DK158727C DK 158727 C DK158727 C DK 158727C DK 340685 A DK340685 A DK 340685A DK 340685 A DK340685 A DK 340685A DK 158727 C DK158727 C DK 158727C
Authority
DK
Denmark
Prior art keywords
procedures
preparing
pharmaceutical preparations
preparations containing
benzodiazepine derivatives
Prior art date
Application number
DK340685A
Other languages
English (en)
Other versions
DK340685D0 (da
DK340685A (da
DK158727B (da
Inventor
Tibor Lang
Jeno Koroesi
Ferenc Andrasi
Peter Botka
Tamas Hamori
Pal Berzsenyi
Katalin Goldschmidt
Gabor Zolyomi
Istvan Elekes
Zsuzsanna Lang
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of DK340685D0 publication Critical patent/DK340685D0/da
Publication of DK340685A publication Critical patent/DK340685A/da
Publication of DK158727B publication Critical patent/DK158727B/da
Application granted granted Critical
Publication of DK158727C publication Critical patent/DK158727C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK340685A 1984-07-27 1985-07-26 5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem DK158727C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU288284 1984-07-27
HU842882A HU191698B (en) 1984-07-27 1984-07-27 Process for producing new 1-aryl-5h-2beta-benzodiazepines

Publications (4)

Publication Number Publication Date
DK340685D0 DK340685D0 (da) 1985-07-26
DK340685A DK340685A (da) 1986-01-28
DK158727B DK158727B (da) 1990-07-09
DK158727C true DK158727C (da) 1990-12-10

Family

ID=10961503

Family Applications (1)

Application Number Title Priority Date Filing Date
DK340685A DK158727C (da) 1984-07-27 1985-07-26 5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem

Country Status (23)

Country Link
US (1) US4614740A (da)
JP (1) JPS6143174A (da)
AT (1) AT393123B (da)
BE (1) BE902953A (da)
CA (1) CA1277660C (da)
CH (1) CH667090A5 (da)
CS (1) CS251795B2 (da)
DD (1) DD236527A5 (da)
DE (1) DE3527117C2 (da)
DK (1) DK158727C (da)
ES (1) ES8608494A1 (da)
FI (1) FI84821C (da)
FR (1) FR2568252B1 (da)
GB (1) GB2162184B (da)
GR (1) GR851853B (da)
HU (1) HU191698B (da)
IT (1) IT1187712B (da)
NL (1) NL8502141A (da)
NO (1) NO162115C (da)
PH (1) PH22420A (da)
PL (1) PL145089B1 (da)
PT (1) PT80870B (da)
SE (1) SE465777B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU195788B (en) * 1986-05-21 1988-07-28 Gyogyszerkutato Intezet Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them
HU198494B (en) * 1986-08-15 1989-10-30 Gyogyszerkutato Intezet Process for producing new 3,4-dihydro-5h-2,3-benzodiazepine derivative and acid addition salts thereof, as well as pharmaceutical compositions comprising same
HU207055B (en) * 1990-10-17 1993-03-01 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivative and pharmaceutical compositions comprising same
US5639751A (en) * 1990-12-21 1997-06-17 Cyogyszerkutato Intezet Kft N-acyl-2,3-benzodiazepine derivatives for treating acute and chronic neurodegenerative disorders
US5521174A (en) * 1990-12-21 1996-05-28 Gyogyszerkutato Intezet Kv. N-acyl-2,3-benzodiazepine derivatives and a method of treating spasms of the skeletal musculature therewith
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
TR199501071A2 (tr) * 1994-08-31 1996-06-21 Lilly Co Eli Dihidro-2,3-benzodiazepin türevlerinin üretilmesi icin stereoselektif islem.
US6288057B1 (en) * 1994-08-31 2001-09-11 Eli Lilly And Company Physical form of dihydro-2,3-benzodiazepine derivative
DE19604920A1 (de) * 1996-02-01 1997-08-07 Schering Ag Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
US5891871A (en) * 1996-03-21 1999-04-06 Cocensys, Inc. Substituted 2,3-benzodiazepin-4-ones and the use thereof
UA67749C2 (uk) * 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
WO2001098280A2 (en) * 2000-06-16 2001-12-27 Annovis, Inc. 5h-2,3-benzodiazepine antagonists of excitatory amino acid receptors
HU225100B1 (hu) * 2000-12-21 2006-06-28 Egyt Gyogyszervegyeszeti Gyar 2,3-Benzodiazepinszármazékok, ilyen hatóanyagot tartalmazó gyógyászati készítmények és alkalmazásuk
US6649607B2 (en) * 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
US6638928B1 (en) 2002-12-03 2003-10-28 Vela Pharmaceuticals, Inc. Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines
AU2003293405A1 (en) * 2002-12-03 2004-06-23 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5h-2,3-benzodiazepine and uses thereof
US6864251B2 (en) * 2002-12-03 2005-03-08 Vela Pharmaceuticals, Inc. Treatment of LTB4-mediated inflammatory disorders with optically-pure (R)-2,3-benzodiazepines
AU2003303312A1 (en) * 2002-12-03 2004-08-30 Vela Pharmaceuticals, Inc. Pharmaceutical composition of 1-(3-hydroxy-4-methoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5h-2,3-benzodiazepine and uses therof
US7022700B2 (en) * 2002-12-03 2006-04-04 Vela Pharmaceuticals, Inc. Method of increasing neutrophil production using optically-pure (R)-2,3-benzodiazepines
US6858605B2 (en) * 2003-02-04 2005-02-22 Ivax Drug Research Institute, Ltd. Substituted 2,3-benzodiazepine derivatives
US20040162284A1 (en) * 2003-02-19 2004-08-19 Harris Herbert W. Method of lowering body temperature with (S) tofisopam
US20040224943A1 (en) * 2003-02-19 2004-11-11 Leventer Steven M. Method of lowering body temperature with (R) - 2,3-benzodiazepines
EP1624875A4 (en) * 2003-05-16 2010-01-20 Vela Acquisition Corp TREATMENT OF GASTROINTESTINAL DYSFUNCTION AND RELATED LOADS WITH ENANTIOMERIC PURE (R) 2,3-BENZODIAZEPINE
US20070021412A1 (en) * 2003-05-16 2007-01-25 Vela Pharmaceuticals, Inc. Treatment of gastrointestinal dysfunction and related stress with an enantiomerically-pure (S) 2,3-benzodiazepine
US20040254173A1 (en) * 2003-06-13 2004-12-16 Leventer Steven M. Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines
HUP0302449A3 (en) * 2003-08-04 2005-06-28 Egis Gyogyszergyar Nyilvanosan 8-chloro-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for producing them
JP4855838B2 (ja) * 2006-02-07 2012-01-18 道夫 本郷 錠剤容器
TW200902024A (en) * 2007-04-02 2009-01-16 Teva Pharma Novel 2,3-benzodiazepine derivatives and their use as antipsychotic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US30014A (en) * 1860-09-11 Bailboad-joint
USRE30014E (en) 1966-12-09 1979-05-29 Egyesult Gyogyazer-es Tapozergyar 1-(3,4-Dimethoxy-phenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine
DK118660B (da) * 1966-12-09 1970-09-21 Egyt Gyogyszervegyeszeti Gyar Analogifremgangsmåde til fremstilling af 1-(3',4'-dimethoxyphenyl)-3-methyl-4-ethyl-6,7-dimethoxy-isoquinolin-N-imid.
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU186760B (en) * 1981-03-12 1985-09-30 Gyogyszerkutato Intezet Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives

Also Published As

Publication number Publication date
GB2162184A (en) 1986-01-29
NL8502141A (nl) 1986-02-17
HUT38324A (en) 1986-05-28
DE3527117C2 (de) 1996-08-08
PL145089B1 (en) 1988-08-31
NO162115B (no) 1989-07-31
DK340685D0 (da) 1985-07-26
ES8608494A1 (es) 1986-07-16
DK340685A (da) 1986-01-28
ES545559A0 (es) 1986-07-16
CA1277660C (en) 1990-12-11
SE8503613D0 (sv) 1985-07-26
CH667090A5 (de) 1988-09-15
AT393123B (de) 1991-08-26
PL254701A1 (en) 1986-09-09
PT80870B (pt) 1987-09-18
FR2568252A1 (fr) 1986-01-31
GB2162184B (en) 1987-12-31
HU191698B (en) 1987-03-30
ATA220185A (de) 1991-01-15
GR851853B (da) 1985-12-02
JPS6143174A (ja) 1986-03-01
SE8503613L (sv) 1986-01-28
DD236527A5 (de) 1986-06-11
IT1187712B (it) 1987-12-23
FI84821C (fi) 1992-01-27
IT8521725A0 (it) 1985-07-26
PH22420A (en) 1988-09-12
FI852906L (fi) 1986-01-28
NO852973L (no) 1986-01-28
DE3527117A1 (de) 1986-01-30
FR2568252B1 (fr) 1987-03-20
GB8518971D0 (en) 1985-09-04
BE902953A (fr) 1986-01-22
JPH0413347B2 (da) 1992-03-09
FI84821B (fi) 1991-10-15
SE465777B (sv) 1991-10-28
NO162115C (no) 1989-11-08
PT80870A (en) 1985-08-01
FI852906A0 (fi) 1985-07-26
CS251795B2 (en) 1987-08-13
DK158727B (da) 1990-07-09
US4614740A (en) 1986-09-30

Similar Documents

Publication Publication Date Title
DK158727C (da) 5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem
DK340785A (da) Quinonderivater, fremgangsmaade til fremstilling af dem og farmaceutisk praeparat indeholdende dem
DK328586D0 (da) Phenylethanolaminotetraliner og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende dem
DK539789D0 (da) Carbostyrilderivater, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant carbostyrilderivat
DK56086D0 (da) 11beta-phenylgonaner, deres fremstilling og farmaceutiske praeparaterindeholdende dem
DK164907C (da) Piperazinderivater, deres fremstilling og farmaceutiske praeparater indeholdende dem
DK218985A (da) Aminocyklopentylaetere, farmaceutiske praeparater indeholdende dem og fremgangsmaade til fremstilling af dem
DK258187A (da) 1-(hydroxystyryl)-5h-2,3-benzodiazepinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem
DK438788A (da) Alkylaminoalkoxyphenylderivater, fremgangsmaade til deres fremstilling og midler indeholdende dem
DK504986D0 (da) 7-acylbenzoxazinoner og deres derivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
DK183986D0 (da) Cyklopentylaetere, fremgangsmaade til fremstilling deraf og laegemiddelpraeparat indeholdende saadanne forbindelser
DK425384D0 (da) Acylindol-derivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater som indeholder dem
DK265788A (da) Hydrazinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater der indeholder dem
DK251888D0 (da) Makrolidderivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
NO871745D0 (no) Benzotiazinonderivater, fremgangsmaate til deres fremstilling, legemidler inneholdende dem og deres anvendelse.
DK123488A (da) 2-oxa-isocephemforbindelser, praeparater indeholdende dem, og fremgangsmaader til fremstilling af dem
DK5785D0 (da) Tricycliske forbindelser, fremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende en saadan forbindelse
DK347789A (da) Cysteinderivater, fremgangsmaade til fremstilling af dem og farmaceutiske praeparater indeholdende saadanne forbindelser
DK258287D0 (da) 3-(hydroxymetyl)-isoquinolinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem
DK165115C (da) Bicycliske catechol-derivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende saadanne derivater
DK110785D0 (da) Carboxyalkyldipeptidderivater, fremgangsmaade til deres fremstilling, midler indeholdende dem og deres anvendelse
DK163826C (da) 1,4-dihydro-3-carboxy-6,8-difluor-4-oxoquinolin-derivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende saadanne derivater
DK465585A (da) Nukleosidderivater, farmaceutiske praeparater indeholdende dem og fremgangsmaade til fremstilling af dem
DK647488D0 (da) 19,11beta-bro-steroider, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater, der indeholder dem
DK612888A (da) Octahydro-indenofuranderivater, fremgangsmaade til fremstilling heraf og farmaceutiske praeparater indeholdende saadanne forbindelser

Legal Events

Date Code Title Description
PBP Patent lapsed