DK1206274T3 - Anvendelse af interleukin-18-inhibitorer til hæmning af tumormetastase - Google Patents

Anvendelse af interleukin-18-inhibitorer til hæmning af tumormetastase

Info

Publication number
DK1206274T3
DK1206274T3 DK00944201T DK00944201T DK1206274T3 DK 1206274 T3 DK1206274 T3 DK 1206274T3 DK 00944201 T DK00944201 T DK 00944201T DK 00944201 T DK00944201 T DK 00944201T DK 1206274 T3 DK1206274 T3 DK 1206274T3
Authority
DK
Denmark
Prior art keywords
interleukin
inhibitors
tumor metastasis
inhibit tumor
inhibit
Prior art date
Application number
DK00944201T
Other languages
Danish (da)
English (en)
Inventor
Charles Dinarello
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of DK1206274T3 publication Critical patent/DK1206274T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK00944201T 1999-07-22 2000-07-17 Anvendelse af interleukin-18-inhibitorer til hæmning af tumormetastase DK1206274T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13104799A IL131047A0 (en) 1999-07-22 1999-07-22 Use of il-18 inhibitors
PCT/IL2000/000419 WO2001007480A2 (en) 1999-07-22 2000-07-17 Use of interleukin-18 inhibitors to inhibit tumor metastasis

Publications (1)

Publication Number Publication Date
DK1206274T3 true DK1206274T3 (da) 2007-08-13

Family

ID=11073044

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00944201T DK1206274T3 (da) 1999-07-22 2000-07-17 Anvendelse af interleukin-18-inhibitorer til hæmning af tumormetastase

Country Status (31)

Country Link
US (1) US7741276B2 (sk)
EP (1) EP1206274B1 (sk)
JP (1) JP4827352B2 (sk)
KR (1) KR100682219B1 (sk)
CN (1) CN1173736C (sk)
AR (1) AR024907A1 (sk)
AT (1) ATE363288T1 (sk)
AU (1) AU782478B2 (sk)
BG (1) BG65800B1 (sk)
BR (1) BR0012675A (sk)
CA (1) CA2380216C (sk)
CY (1) CY1107932T1 (sk)
CZ (1) CZ302114B6 (sk)
DE (2) DE1206274T1 (sk)
DK (1) DK1206274T3 (sk)
EA (1) EA005419B1 (sk)
EE (1) EE04838B1 (sk)
ES (1) ES2186596T3 (sk)
HK (1) HK1048248B (sk)
HU (1) HU228780B1 (sk)
IL (2) IL131047A0 (sk)
MX (1) MXPA02000838A (sk)
NO (1) NO329827B1 (sk)
NZ (1) NZ516535A (sk)
PL (1) PL202477B1 (sk)
PT (1) PT1206274E (sk)
SK (1) SK287522B6 (sk)
TR (1) TR200200169T2 (sk)
UA (1) UA73745C2 (sk)
WO (1) WO2001007480A2 (sk)
ZA (1) ZA200200390B (sk)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201305214A (zh) 2000-02-10 2013-02-01 Abbott Gmbh & Co Kg 與人類間白素-18結合之抗體,及其製法及用途
EP1331943A4 (en) 2000-10-11 2005-01-26 Viron Therapeutics Inc NUCLEIC ACID MOLECULES AND POLYPEPTIDES FOR IMMUNOMODULATION
US7718368B2 (en) 2000-12-04 2010-05-18 Viron Therapeutics Inc. Immunomodulatory protein and useful embodiments thereof
KR101015682B1 (ko) * 2002-10-08 2011-02-22 아레스 트레이딩 에스.에이. Il-18bp에 결합할 수 있고 제 2 사이토킨의 활성을저해할 수 있는 사이토킨의 용도
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
PT1885753E (pt) 2005-06-03 2011-10-06 Ares Trading Sa Produção de proteína recombinante de ligação a il-18
CA2610804C (en) 2005-06-10 2013-11-19 Ares Trading S.A. Process for the purification of il-18 binding protein
CL2008002153A1 (es) 2007-07-24 2009-06-05 Amgen Inc Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
US9812033B2 (en) * 2013-03-06 2017-11-07 Venkatesh R. Chari Tactile graphic display
WO2023178192A1 (en) 2022-03-15 2023-09-21 Compugen Ltd. Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ299210A (en) * 1992-09-02 2000-08-25 Isis Pharmaceuticals Inc Treating diseases characterised by changes in intercellular adhesion molecules using coding sequences hybridizable with those encoding proteins involved in synthesis of such molecules
US7141393B2 (en) * 1996-12-26 2006-11-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18-receptor proteins
BR9810409A (pt) * 1997-03-18 2000-08-22 Basf Ag Métodos e composições para a modulação de responsividade a corticosteróides
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use

Also Published As

Publication number Publication date
BRPI0012675B1 (pt) 2001-02-01
CA2380216A1 (en) 2001-02-01
EP1206274A2 (en) 2002-05-22
BG65800B1 (bg) 2009-12-31
DE1206274T1 (de) 2002-11-14
KR100682219B1 (ko) 2007-02-12
ATE363288T1 (de) 2007-06-15
US7741276B2 (en) 2010-06-22
JP4827352B2 (ja) 2011-11-30
ES2186596T3 (es) 2007-11-16
CN1364086A (zh) 2002-08-14
WO2001007480A2 (en) 2001-02-01
HK1048248A1 (en) 2003-03-28
UA73745C2 (en) 2005-09-15
BG106311A (en) 2002-08-30
CY1107932T1 (el) 2013-09-04
HUP0202107A3 (en) 2005-01-28
WO2001007480A3 (en) 2001-05-10
NO20020153D0 (no) 2002-01-11
AR024907A1 (es) 2002-10-30
EA005419B1 (ru) 2005-02-24
HU228780B1 (en) 2013-05-28
AU5843200A (en) 2001-02-13
CZ2002195A3 (cs) 2002-06-12
SK882002A3 (en) 2002-07-02
PT1206274E (pt) 2007-07-06
HK1048248B (zh) 2005-04-22
JP2003505472A (ja) 2003-02-12
KR20020027493A (ko) 2002-04-13
US20080003216A1 (en) 2008-01-03
PL202477B1 (pl) 2009-06-30
NZ516535A (en) 2004-04-30
ZA200200390B (en) 2003-04-30
CA2380216C (en) 2012-01-31
HUP0202107A2 (en) 2002-10-28
MXPA02000838A (es) 2002-07-30
ES2186596T1 (es) 2003-05-16
CZ302114B6 (cs) 2010-10-20
CN1173736C (zh) 2004-11-03
DE60035049D1 (de) 2007-07-12
DE60035049T2 (de) 2007-09-27
IL131047A0 (en) 2001-01-28
EP1206274B1 (en) 2007-05-30
EE04838B1 (et) 2007-06-15
IL147675A (en) 2009-05-04
BRPI0012675B8 (sk) 2021-05-25
EE200200032A (et) 2003-02-17
EA200200189A1 (ru) 2002-12-26
AU782478B2 (en) 2005-08-04
SK287522B6 (sk) 2011-01-04
PL353732A1 (en) 2003-12-01
NO20020153L (no) 2002-03-11
NO329827B1 (no) 2011-01-03
BR0012675A (pt) 2002-04-09
TR200200169T2 (tr) 2002-06-21

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